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Original Research

RASSF1A hypermethylation is associated with ASXL1 mutation and indicates an adverse outcome in non-M3 acute myeloid leukemia

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Pages 4143-4151 | Published online: 22 Aug 2017

References

  • FerraraFSchifferCAAcute myeloid leukaemia in adultsLancet2013381986548449523399072
  • LevineRLMolecular pathogenesis of AML: translating insights to the clinicBest Pract Res Clin Haematol201326324524824309525
  • KhaledSAl MalkiMMarcucciGAcute myeloid leukemia: biologic, prognostic and therapeutic insightsOncology (Williston Park)201630431832927085330
  • JabbourECortesJRavandiFO’BrienSKantarjianHTargeted therapies in hematology and their impact on patient care: chronic and acute myeloid leukemiaSemin Hematol201350427128324246694
  • PastoreFLevineRLEpigenetic regulators and their impact on therapy in acute myeloid leukemiaHaematologica2016101326927826928248
  • Conway O’BrienEPrideauxSChevassutTThe epigenetic landscape of acute myeloid leukemiaAdv Hematol2014201410317524778653
  • HennessyBTGarcia-ManeroGKantarjianHMGilesFJDNA methylation in haematological malignancies: the role of decitabineExpert Opin Investig Drugs2003121219851993
  • SchoofsTMüller-TidowCDNA methylation as a pathogenic event and as a therapeutic target in AMLCancer Treat Rev201137Suppl 1S13S1821612874
  • LiMGaoLLiZCTNNA1 hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcomeOncotarget2016721314543146527129146
  • GaoLLiuFZhangHSunJMaYCHFR hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcomeGenes Chromosomes Cancer201655215816826542416
  • LiYGaoLLuoXEpigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathwayBlood2013121349950923223432
  • van der WeydenLAdamsDJThe Ras-association domain family (RASSF) members and their role in human tumourigenesisBiochim Biophys Acta200717761588517692468
  • DonningerHVosMDClarkGJThe RASSF1A tumor suppressorJ Cell Sci2007120Pt 183163317217878233
  • HessonLBCooperWNLatifFThe role of RASSF1A methylation in cancerDis Markers2007231–2738717325427
  • SimonsAShafferLGHastingsRJCytogenetic nomenclature: changes in the ISCN 2013 compared to the 2009 editionCytogenet Genome Res201314111623817294
  • SlovakMLKopeckyKJCassilethPAKaryotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group StudyBlood200096134075408311110676
  • LiuFGaoLJingYDetection and clinical significance of gene rearrangements in Chinese patients with adult acute lymphoblastic leukemiaLeuk Lymphoma20135471521152623210573
  • ShenYZhuYMFanXGene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemiaBlood2011118205593560321881046
  • GuanLGaoLWangLThe frequency and clinical significance of IDH1 mutations in Chinese acute myeloid leukemia patientsPLoS One2013812e8333424376688
  • ChenTCHouHAChouWCDynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndromeBlood Cancer J201441e17724442206
  • HaferlachTNagataYGrossmannVLandscape of genetic lesions in 944 patients with myelodysplastic syndromesLeukemia201428224124724220272
  • ItzyksonRKosmiderORennevilleAPrognostic score including gene mutations in chronic myelomonocytic leukemiaJ Clin Oncol201331192428243623690417
  • YangJSchifferCAGenetic biomarkers in acute myeloid leukemia: will the promise of improving treatment outcomes be realized?Expert Rev Hematol20125439540722992234
  • MuratiABrecquevilleMDevillierRMozziconacciMJGelsi-BoyerVBirnbaumDMyeloid malignancies: mutations, models and managementBMC Cancer20121230422823977
  • ShihAHAbdel-WahabOPatelJPLevineRLThe role of mutations in epigenetic regulators in myeloid malignanciesNat Rev Cancer201212959961222898539
  • JasielecJSalouraVGodleyLAThe mechanistic role of DNA methylation in myeloid leukemogenesisLeukemia20142891765177324913729
  • SmithBDBeachCLMahmoudDWeberLHenkHJSurvival and hospitalization among patients with acute myeloid leukemia treated with azacitidine or decitabine in a large managed care population: a real-world, retrospective, claims-based, comparative analysisExp Hematol Oncol2014311024666795
  • YunSVinceletteNDAbrahamIRobertsonKDFernandez-ZapicoMEPatnaikMMTargeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trialsClin Epigenetics201686827307795
  • DingKFuRLiuHNachnaniDAShaoZHEffects of decitabine on megakaryocyte maturation in patients with myelodysplastic syndromesOncol Lett20161142347235227073478
  • GriffithsEAGoreSDHookerCAcute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylationLeuk Lymphoma20105191711171920795789
  • JohanMFBowenDTFrewMEGoodeveACReillyJTAberrant methylation of the negative regulators RASSFIA, SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemiaBr J Haematol20051291606515801956
  • AvramouliATsochasSMandalaEMethylation status of RASSF1A in patients with chronic myeloid leukemiaLeuk Res20093381130113219193434
  • PaschkaPSchlenkRFGaidzikVIASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study GroupHaematologica2015100332433025596267
  • ShivarovVGueorguievaRIvanovaMTiuRVASXL1 mutations define a subgroup of patients with acute myeloid leukemia with distinct gene expression profile and poor prognosis: a meta-analysis of 3311 adult patients with acute myeloid leukemiaLeuk Lymphoma20155661881188325308295
  • SchnittgerSEderCJerominSASXL1 exon 12 mutations are frequent in AML with intermediate risk karyotype and are independently associated with an adverse outcomeLeukemia2013271829123018865
  • OdenikeOThirmanMJArtzASGodleyLALarsonRAStockWGene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?Semin Oncol201138219621421421110
  • TakahashiSCurrent findings for recurring mutations in acute myeloid leukemiaJ Hematol Oncol201143621917154
  • GillHLeungAYKwongYLMolecular targeted therapy in acute myeloid leukemiaFuture Oncol201612682783826828965