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Original Research

Synaptotagmin-7 is overexpressed in hepatocellular carcinoma and regulates hepatocellular carcinoma cell proliferation via Chk1–p53 signaling

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Pages 4283-4293 | Published online: 29 Aug 2017

References

  • El-SeragHBKanwalFEpidemiology of hepatocellular carcinoma in the United States: where are we? Where do we go?Hepatology20146051767177524839253
  • ChenWZhengRBaadePDCancer statistics in China, 2015CA Cancer J Clin201666211513226808342
  • LlovetJMRicciSMazzaferroVSHARP Investigators Study GroupSorafenib in advanced hepatocellular carcinomaN Engl J Med2008359437839018650514
  • WangZQuLDengBSTYK1 promotes epithelial-mesenchymal transition and tumor metastasis in human hepatocellular carcinoma through MEK/ERK and PI3K/AKT signalingSci Rep201663320527628214
  • ChapmanERHow does synaptotagmin trigger neurotransmitter release?Annu Rev Biochem20087761564118275379
  • GustavssonNHanWCalcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretionBiosci Rep200929424525919500075
  • FukudaMKannoESatohMSaegusaCYamamotoASynaptotagmin VII is targeted to dense-core vesicles and regulates their Ca2+ -dependent exocytosis in PC12 cellsJ Biol Chem200427950526775268415456748
  • WeberJPToft-BertelsenTLMohrmannRDelgado-MartinezISorensenJBSynaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23PLoS One2014911e11403325422940
  • GustavssonNWeiSHHoangDNSynaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreasJ Physiol2009587Pt 61169117819171650
  • WuBWeiSPetersenNSynaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from beta-cellsProc Natl Acad Sci U S A20151123299961000126216970
  • GlavanGSeeREZivinMDifferential patterns of synaptotagmin7 mRNA expression in rats with kainate- and pilocarpine-induced seizuresPLoS One201275e3611422567130
  • ColvinRAMeansTKDiefenbachTJSynaptotagmin-mediated vesicle fusion regulates cell migrationNat Immunol201011649550220473299
  • SvecDTichopadANovosadovaVPfafflMWKubistaMHow good is a PCR efficiency estimate: recommendations for precise and robust qPCR efficiency assessmentsBiomol Detect Quantif2015391627077029
  • SunWYaoLJiangBGuoLWangQSpindle and kinetochore-associated protein 1 is overexpressed in gastric cancer and modulates cell growthMol Cell Biochem20143911–216717424627241
  • NabzdykCSChunMPradhan NabzdykLYoshidaSLoGerfoFWDifferential susceptibility of human primary aortic and coronary artery vascular cells to RNA interferenceBiochem Biophys Res Commun2012425226126522842581
  • WangJYuSCuiLRole of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancerBMC Cancer2015159025884313
  • ZhuQGongLWangJmiR-10b exerts oncogenic activity in human hepatocellular carcinoma cells by targeting expression of CUB and sushi multiple domains 1 (CSMD1)BMC Cancer201616180627756250
  • FigarolaJLSinghalJTompkinsJDSR4 uncouples mitochondrial oxidative phosphorylation, modulates AMP-dependent kinase (AMPK)-mammalian target of rapamycin (mTOR) signaling, and inhibits proliferation of HepG2 hepatocarcinoma cellsJ Biol Chem201529051303213034126534958
  • JiangPCaoJBaiWHLentivirus-mediated siRNA targeting ER-alpha inhibits tumorigenesis and induces apoptosis in hepatocarcinoma cellsBioMed Res Int2015201549068126413526
  • QiJLiTBianHSNAI1 promotes the development of HCC through the enhancement of proliferation and inhibition of apoptosisFEBS Open Bio201664326337
  • ShihAMVargheseLBittarAParkSHChungJMShinOHDysregulation of norepinephrine release in the absence of functional synaptotagmin 7J Cell Biochem201611761446145327043247
  • PengXMooreMMathurAPlexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosisFASEB J201630124056407027609773
  • ZhuHWuTCChenWQScreening for differentially expressed genes between left- and right-sided colon carcinoma by microarray analysisOncol Lett20136235335824137329
  • LuMBerglundELarssonCHöögAFarneboLOBränströmRCalmodulin and calmodulin-dependent protein kinase II inhibit hormone secretion in human parathyroid adenomaJ Endocrinol20112081313920974637
  • JunHJJohnsonHBronsonRTde FeraudySWhiteFCharestAThe oncogenic lung cancer fusion kinase CD74-ROS activates a novel invasiveness pathway through E-Syt1 phosphorylationCancer Res201272153764377422659450
  • ZhangYHunterTRoles of Chk1 in cell biology and cancer therapyInt J Cancer201413451013102323613359
  • WuFChenWJYanLMus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathwayCancer Med20165237038526714930
  • HientzKMohrABhakta-GuhaDEfferthTThe role of p53 in cancer drug resistance and targeted chemotherapyOncotarget2017858921894627888811
  • WangZZhangHZhouJEriocitrin from lemon suppresses the proliferation of human hepatocellular carcinoma cells through inducing apoptosis and arresting cell cycleCancer Chemother Pharmacol20167861143115027766389
  • LezinaLPurmessurNAntonovAVmiR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stressCell Death Dis2013412e95324336073
  • LeeHKimYJeongJHRyuJHKimWYATM/CHK/p53 pathway dependent chemopreventive and therapeutic activity on lung cancer by pterostilbenePLoS One2016119e016233527612029