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Original Research

Decreased expression of LKB1 predicts poor prognosis in pancreatic neuroendocrine tumor patients undergoing curative resection

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Pages 1259-1265 | Published online: 06 Mar 2018

References

  • YoungKIyerRMorgansteinDChauICunninghamDStarlingNPancreatic neuroendocrine tumors: a reviewFuture Oncol201511585386425757686
  • SimardEPWardEMSiegelRJemalACancers with increasing incidence trends in the United States: 1999 through 2008CA Cancer J Clin201262211812822281605
  • MinterRMSimeoneDMContemporary management of nonfunctioning pancreatic neuroendocrine tumorsJ Gastrointest Surg201216243544622009463
  • FalconiMErikssonBKaltsasGENETS Consensus guidelines update for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine tumorsNeuroendocrinol20161032153171
  • ChiruvellaAKoobyDASurgical management of pancreatic neuroendocrine tumorsSurg Oncol Clin N Am201625240142127013372
  • SolorzanoCCLeeJEPistersPWNonfunctioning islet cell carcinoma of the pancreas: survival results in a contemporary series of 163 patientsSurgery200113061078108511742342
  • HaynesABDeshpandeVIngkakulTImplications of incidentally discovered, nonfunctioning pancreatic endocrine tumors: short-term and long-term patient outcomesArch Surg2011146553453821576607
  • YaoJCHassanMPhanAOne hundred years after “carcinoid”: epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United StatesJ Clin Oncol200826183063307218565894
  • WeiIHHarmonCMArceritoMChengDFMinterRMSimeoneDMTumor-associated macrophages are a useful biomarker to predict recurrence after surgical resection of nonfunctional pancreatic neuroendocrine tumorsAnn Surg201426061088109425389924
  • FitzgeraldTLMosqueraCVoraHSVohraNAZervosEEIndications for surgical resection in low-grade pancreatic neuroendocrine tumorsAm Surg201682873774227657591
  • HemminkiAMarkieDTomlinsonIA serine/threonine kinase gene defective in Peutz-Jeghers syndromeNature199839166631841879428765
  • JenneDEReimannHNezuJPeutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinaseNat Genet199818138439425897
  • HardieDGNew roles for the LKB1-->AMPK pathwayCurr Opin Cell Biol200517216717315780593
  • MirouseVBillaudMThe LKB1/AMPK polarity pathwayFEBS Lett2011585798198521185289
  • NakanoATakashimaSLKB1 and AMP-activated protein kinase: regulators of cell polarityGenes Cells201217973774722892070
  • UddLMakelaTPLKB1 signaling in advancing cell differentiationFam Cancer201110342543521519908
  • WilliamsTBrenmanJELKB1 and AMPK in cell polarity and divisionTrends Cell Biol200818419319818314332
  • JansenMTen KloosterJPOfferhausGJCleversHLKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolismPhysiol Rev200989377779819584313
  • YangJYJiangSHLiuDJDecreased LKB1 predicts poor prognosis in pancreatic ductal adenocarcinomaSci Rep201551057526015068
  • Linher-MelvilleKZantingeSSinghGLiver kinase B1 expression (LKB1) is repressed by estrogen receptor alpha (ERalpha) in MCF-7 human breast cancer cellsBiochem Biophys Res Commun201241731063106822226967
  • MackHIMungerKThe LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell linesVirology20134461–291624074562
  • TigliHSevenDTuncMLKB1 mutations and their correlation with LKB1 and Rheb expression in bladder cancerMol Carcinog201352866066522457270
  • GrossRWPattiGJMilbrandtJLoss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancerNat Neurosci2014353546553
  • HeTYTsaiLHHuangCCChouMCLeeHLKB1 loss at transcriptional level promotes tumor malignancy and poor patient outcomes in colorectal cancerAnn Surg Oncol201421Suppl 4S703S71024879590
  • LiFHanXLiFLKB1 Inactivation Elicits a redox imbalance to modulate non-small cell lung cancer plasticity and therapeutic responseCancer Cell201527569871125936644
  • HuangYHChenZKHuangKTDecreased expression of LKB1 correlates with poor prognosis in hepatocellular carcinoma patients undergoing hepatectomyAPJCP20131431985198823679304
  • AminRMHiroshimaKIyodaALKB1 protein expression in neuroendocrine tumors of the lungPathol Int2008582848818199157
  • Sanchez-CespedesMA role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndromeOncogene200726577825783217599048
  • KorsseSEPeppelenboschMPvan VeelenWTargeting LKB1 signaling in cancerBiochimi Biophys Acta201318352194210
  • GanRYLiHBRecent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive functionInt J Mol Sci2014159166981671825244018
  • JiHRamseyMRHayesDNLKB1 modulates lung cancer differentiation and metastasisNature2007448715580781017676035
  • KanJYYenMCWangJYNesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancerOncotarget2016721313363134927150059
  • de WildeRFOttenhofNAJansenMAnalysis of LKB1 mutations and other molecular alterations in pancreatic acinar cell carcinomaMod Pathol20112491229123621572398
  • KoneMPullenTJSunGLKB1 and AMPK differentially regulate pancreatic beta-cell identityFASEB J201428114972498525070369
  • NakadaDSaundersTLMorrisonSJLkb1 regulates cell cycle and energy metabolism in haematopoietic stem cellsNature2010468732465365821124450
  • ShellyMPooMMRole of LKB1-SAD/MARK pathway in neuronal polarizationDev Neurobiol201171650852721416623
  • ShawRJBardeesyNManningBDThe LKB1 tumor suppressor negatively regulates mTOR signalingCancer Cell200461919915261145
  • VandammeTPeetersMDoganFWhole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1J Mol Endocrinol201554213714725612765
  • ScarpaAChangDKNonesKWhole-genome landscape of pancreatic neuroendocrine tumoursNature20175437643657128199314
  • MissiagliaEDalaiIBarbiSPancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathwayJ Clin Oncol201028224525519917848