References
- BaxevanisCNPerezSAPapamichailMCombinatorial treatments including vaccines, chemotherapy and monoclonal antibodies for cancer therapyCancer Immunol Immunother200958331732418704409
- JenaBDottiGCooperLJRedirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptorBlood201011671035104420439624
- MaudeSLFreyNShawPAChimeric antigen receptor T cells for sustained remissions in leukemiaN Engl J Med2014371161507151725317870
- BrentjensRJDavilaMLRiviereICD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemiaSci Transl Med20135177177ra138
- GruppSAKalosMBarrettDChimeric antigen receptor-modified T cells for acute lymphoid leukemiaN Engl J Med2013368161509151823527958
- PorterDLLevineBLKalosMBaggAJuneCHChimeric antigen receptor-modified T cells in chronic lymphoid leukemiaN Engl J Med2011365872573321830940
- GarfallALMausMVHwangWTChimeric antigen receptor T cells against CD19 for multiple myelomaN Engl J Med2015373111040104726352815
- YangYJacobyEFryTJChallenges and opportunities of allogeneic donor-derived CAR T cellsCurr Opin Hematol201522650951526390167
- BurgosSAChandurkarVTsoukasMAInsulin resistance of protein anabolism accompanies that of glucose metabolism in lean, glucose-tolerant offspring of persons with type 2 diabetesBMJ Open Diabetes Res Care201641e000312
- NascimbeniFDalla SaldaACarubbiFEnergy balance, glucose and lipid metabolism, cardiovascular risk and liver disease burden in adult patients with type 1 Gaucher diseaseBlood Cells Mol Dis201668748027839982
- Martinez-OutschoornUEPeiris-PagesMPestellRGSotgiaFLisantiMPCancer metabolism: a therapeutic perspectiveNat Rev Clin Oncol2017141113127141887
- DimeloeSBurgenerAVGrahlertJHessCT-cell metabolism governing activation, proliferation and differentiation; a modular viewImmunology20171501354427479920
- BaileyCJBiguanides and NIDDMDiabetes Care19921567557721600835
- BaileyCJTurnerRCMetforminN Engl J Med199633495745798569826
- RicoMBaglioniMBondarenkoMMetformin and propranolol combination prevents cancer progression and metastasis in different breast cancer modelsOncotarget2017822874288927926515
- ZhuMZhangQWangXMetformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathwayOncotarget2016751841908420027705937
- ZhangPLiHTanXChenLWangSAssociation of metformin use with cancer incidence and mortality: a meta-analysisCancer Epidemiol201337320721823352629
- CurrieCJPooleCDJenkins-JonesSGaleEAJohnsonJAMorganCLMortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survivalDiabetes Care201235229930422266734
- ChengSCQuintinJCramerRAmTOR- and HIF-1alpha-mediated aerobic glycolysis as metabolic basis for trained immunityScience20143456204125068425258083
- EikawaSNishidaMMizukamiSYamazakiCNakayamaEUdonoHImmune-mediated antitumor effect by type 2 diabetes drug, metforminProc Natl Acad Sci U S A201511261809181425624476
- ChamCMGajewskiTFGlucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cellsJ Immunol200517484670467715814691
- AlmeidaLLochnerMBerodLSparwasserTMetabolic pathways in T cell activation and lineage differentiationSemin Immunol201628551452427825556
- ChiHRegulation and function of mTOR signalling in T cell fate decisionsNat Rev Immunol201212532533822517423
- YangKChiHmTOR and metabolic pathways in T cell quiescence and functional activationSemin Immunol201224642142823375549
- SongHWangHWuWInhibitory role of reactive oxygen species in the differentiation of multipotent vascular stem cells into vascular smooth muscle cells in rats: a novel aspect of traditional culture of rat aortic smooth muscle cellsCell Tissue Res201536219711326022334
- ZhangYMuQZhouZProtective effect of irisin on atherosclerosis via suppressing oxidized low density lipoprotein induced vascular inflammation and endothelial dysfunctionPLoS One2016116e015803827355581
- EvansJMDonnellyLAEmslie-SmithAMAlessiDRMorrisADMetformin and reduced risk of cancer in diabetic patientsBMJ200533075031304130515849206
- DowlingRJGoodwinPJStambolicVUnderstanding the benefit of metformin use in cancer treatmentBMC Med201193321470407
- LanBZhangJZhangPMetformin suppresses CRC growth by inducing apoptosis via ADORA1Front Biosci (Landmark Ed)20172224825727814614
- AlalemMRayARayBKMetformin induces degradation of mTOR protein in breast cancer cellsCancer Med20165113194320427748082
- GaldieriLGatlaHVancurovaIVancuraAActivation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cellsJ Biol Chem201629148251542516627733682
- GongJKelekarGShenJShenJKaurSMitaMThe expanding role of metformin in cancer: an update on antitumor mechanisms and clinical developmentTarget Oncol201611444746726864078
- ChenSCBrooksRHouskeeperJMetformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanismsMol Cell Endocrinol2016440576827856330
- FinlayDKRosenzweigESinclairLVPDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cellsJ Exp Med2012209132441245323183047
- WangRDillonCPShiLZThe transcription factor Myc controls metabolic reprogramming upon T lymphocyte activationImmunity201135687188222195744
- NakamuraHMakinoYOkamotoKTCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cellsJ Immunol2005174127592759915944259