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Review

The role of Hippo signal pathway in breast cancer metastasis

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Pages 2185-2193 | Published online: 17 Apr 2018

References

  • AltobelliERapacchiettaLAngelettiPBreast cancer screening programmes across the WHO European region: differences among countries based on national income levelInt J Environ Res Public Health2017144E45228441745
  • SiegelRLMillerKDJemalACancer statistics, 2018CA Cancer J Clin201868173029313949
  • GinsburgOBrayFColemanMPThe global burden of women’s cancers: a grand challenge in global healthLancet20163891007184786027814965
  • LiXDangXSunXExpression of survivin and VEGF-C in breast cancer tissue and its relation to lymphatic metastasisEur J Gynaecol Oncol201233217818222611959
  • TalmadgeJEFidlerIJAACR centennial series: the biology of cancer metastasis: historical perspectiveCancer Res201070145649566920610625
  • FuVPlouffeSWGuanKLThe Hippo pathway in organ development, homeostasis, and regenerationCurr Opin Cell Biol20184999107
  • MengZMoroishiTGuanKLMechanisms of Hippo pathway regulationGenes Dev201630111726728553
  • JusticeRWZilianOWoodsDFNollMBryantPJThe Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferationGenes Dev1995955345467698644
  • ZhaoBLiLGuanKLHippo signalling at a glanceCell Sci20101232340014006
  • BarryERCamargoFDThe Hippo superhighway: signalling cross roads converging on the Hippo/Yap pathway in stem cells and developmentCurr Opin Cell Biol20132524725323312716
  • VarelasXThe Hippo pathway effectors TAZ and YAP in development, homeostasis and diseaseDevelopment201414181614162624715453
  • YuFXMengZPlouffeSWGuanKLHippo pathway regulation of gastrointestinal tissuesAnnu Rev Physiol20147720122725293527
  • MoroishiTHansenCGGuanKLThe emerging roles of YAP and TAZ in cancerNat Rev Cancer2015152737925592648
  • PiccoloSDupontSCordenonsiMThe biology of YAP/TAZ: hippo signalling and beyondPhysiol Rev20149441287131225287865
  • AtkinsMPotierDRomanelliLAn ectopic network of transcription factors regulated by hippo signaling drives growth and invasion of a malignant tumor modelCurr Biol201626162101211327476594
  • ZhaoBWeiXMLiWQInactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth controlGenes Dev200721212747276117974916
  • HarveyKTaponNThe Salvador-Warts-Hippo pathway an emerging tumour-suppressor networkNat Rev Cancer20077318219117318211
  • ZhaoBLiLLeiQYGuanKLThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionGenes Dev201024986287420439427
  • HoaLKulaberogluYGundogduRThe characterisation of LATS2 kinase regulation in Hippo-YAP signallingCell Signal201628548849726898830
  • LiuCYLvXBLiTTPP1 cooperates with ASPP2 to dephosphorylate and activate TAZJ Biol Chem201128675558556621189257
  • YuFXZhaoBGuanKLHippo pathway in organ size control, tissue homeostasis, and cancerCell2015163481182826544935
  • LiQLiSXMana-CapelliSThe conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in DrosophilaDev Cell201431329130425453828
  • MengZPMoroishiTMottier-PavieVMAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathwayNat Commun20156835726437443
  • ZhengYGWangWLiuBDengHUsterEPanDIdentification of happyhour/MAP4K as alternative Hpo/Mst-like kinases in the hippo kinase cascadeDev Cell201534664265526364751
  • HuangWLvXBLiuCYThe N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibitionJ Biol Chem201228731262452625322692215
  • LeiQYZhangHZhaoBTAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathwayMol Cell Biol20082872426243618227151
  • SchlegelmilchKMohseniMKirakOYAP1 acts downstream of α-catenin to control epidermal proliferationCell2011144578279521376238
  • KimMKimTJohnsonRLLimDSTranscriptional co-repressor function of the hippo pathway transducers YAP and TAZCell Rep201511227028225843714
  • ImajoMMiyatakeKIimuraAMiyamotoANishidaEA molecular mechanism that links Hippo signalling to the inhibition of Wnt/beta-catenin signallingEMBO J20123151109112222234184
  • FujiiMToyodaTNakanishiHTGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growthJ Exp Med2012209347949422329991
  • UrtasunRLatasaMUDemartisMIConnective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activationHepatology20115462149215821800344
  • BritschgiADussSKimSThe Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERαNature2017541763854154528068668
  • ZhouXWangSYWangZEstrogen regulates Hippo signalling via GPERin breast cancerClin Invest2015125521232135
  • SorrentinoGRuggeriNSpecchiaVMetabolic control of YAP and TAZ by the mevalonate pathwayNat Cell Biol201416435736624658687
  • Van RensbergHJJAzadTLingMThe Hippo pathway component TAZ promotes immune evasion in human cancer through PD-L1Cancer Res20187861457147029339539
  • DethlefsenCHansenLSLillelundCExercise-induced catecholamines activate the Hippo tumor suppressor pathway to reduce risks of breast cancer developmentCancer Res201777184894490428887324
  • SorrentinoGRuggeriNZanniniAGlucocorticoid receptor signalling activates YAP in breast cancerNat Commun201781407328102225
  • BosPDZhangXHFNadalCGenes that mediate breast cancer metastasis to the brainNature200945972491005100919421193
  • ChenQZhangNGrayRSA temporal requirement for Hippo signalling in mammary gland differentiation, growth and tumorigenesisGenes Dev201428543243724589775
  • RashidianJLe ScolanEJiXSki regulates Hippo and TAZ signalling to suppress breast cancer progressionSci Signal20158363ra1425670202
  • LiCWangSXingZA ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasisNat Cell Biol201719210611928114269
  • BartucciMDattiloRMoriconiCTAZ is required for metastatic activity and chemoresistance of breast cancer stem cellsOncogene201534668169024531710
  • XiangLGilkesDMHuHHIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cellsOncotarget2015614117681177826059435
  • BendinelliPMaroniPMatteucciEHypoxia inducible factor-1is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WW domain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancerEur J Cancer201349112608261823566416
  • MaroniPMatteucciEDragoLHypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1 stabilization/nuclear translocation in bone metastasis from breast carcinomaExp Cell Res2015330228729925447306
  • WangJRouseCJasperJSPendergastAMABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signallingSci Signal20169413ra1226838548
  • LaiDHoKCHaoYYangXTaxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGFCancer Res20117172728273821349946
  • LehnSTobinNPSimsAHDecreased expression of YAP is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen responseBMC Cancer20141411924559095
  • Heidary ArashEShibanASongSAttisanoLMARK4 inhibits Hippo signalling to promote proliferation and migration of breast cancer cellsEMBO Rep201718342043628183853
  • HayBAGuoMCoupling cell growth, proliferation, and death. Hippo weighs inDev Cell20035336136312967554
  • VisserSYangXLATS tumor suppressor: a new governor of cellular homeostasisCell Cycle20109193892390320935475
  • CooperJGiancottiFGCancer: a new role for non-canonical Hippo signallingCell Res201727445946028244491
  • LuoX-LLiZ-MYanQEffects of MST1 on cell proliferation and apoptosis of human breast carcinoma cell line MCF-7Tumor20082810852854
  • OverholtzerMZhangJMSmolenGATransforming properties of YAP, a candidate oncogene on the chromosome 11q22 ampliconProc Natl Acad Sci U S A200610333124051241016894141
  • SharifGMSchmidtMOYiCCell growth density modulates cancer cell vascular invasion via Hippo pathway activity and CXCR2 signalingOncogene201534485879588925772246
  • LeiQYZhangHZhaoBTAZ promotes cell proliferation and epithelial mesenchymal transition and is inhibited by the hippo pathwayMol Cell Biol20082872426243618227151
  • MiWLinQChildressCGeranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migrationOncogene201534243095310625109332
  • ChanSWLimCJGuoKA role for TAZ in migration, invasion and tumorigenesis of breast cancer cellsCancer Res20086882592259818413727
  • WangYLiuJYingXLinPCZhouBPTwist-mediated epithelial-mesenchymal transition promotes breast tumor cell invasion via inhibition of Hippo pathwaySci Rep201662460627094683
  • WangHDuYCZhouXJLiuHTangSCThe dual functions of YAP-1 to promote and inhibit cell growth in human malignancyCancer Metastasis Rev201433117318224346160
  • YuanMTomlinsonVLaraRYes-associated protein (YAP) functions as a tumor suppressor in breastCell Death Differ200815111752175918617895
  • Jaramillo-RodriguezYCerda-FloresRMRuiz-RamosRYAP expression in normal and neoplastic breast tissue: an immunohistochemical studyArch Med Res201445322322824606817
  • TufailRJordaMZhaoWReisINawazZLoss of yes-associated protein (YAP) expression is associated with estrogen and progesterone receptors negativity in invasive breast carcinomasBreast Cancer Res Treat2012313743750
  • MatallanasDRomanoDYeeKRASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor proteinMol Cell200727696297517889669
  • WangXDSuLOuQYes-associated protein promotes tumour development in luminal epithelial derived breast cancerEur J Cancer20124881227123422056638
  • KimSKJungWHKooJSYes-associated protein (YAP) is differentially expressed in tumor and stroma according to the molecular subtype of breast cancerInt J Clin Exp Pathol201473224323425031743
  • ViciPMottoleseMPizzutiLThe Hippo transducer TAZ as a biomarker of pathological complete response in HER2-positive breast cancer patients treated with trastuzumab-based neoadjuvant therapyOncotarget20145209619962525294813
  • LehnSTobinNPSimsAHDecreased expression of yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen responseBMC Cancer20141411924559095
  • Min KimHKimSKJungWHKooJSMetaplastic carcinoma show different expression pattern of YAP compared to triple-negative breast cancerTumor Biol201436212071212
  • Díaz-MartínJLópez-GarcíaMÁRomero-PérezLNuclear TAZ expression associateswith the triple-negative phenotype in breast cancerEndocr Relat Cancer201522344345425870251
  • ErcolaniCDi BenedettoATerrenatoIExpression of phosphorylated Hippo pathway kinases (MST1/2 and LATS1/2) in HER2-positive and triple-negative breast cancer patients treated with neoadjuvant therapyCancer Biol Ther201718533934628387539
  • Di BenedettoAMottoleseMSperatiFAssociation between AXL, Hippo transducers, and survival outcomes in male breast cancerJ Cell Physiol201723282246225227987320
  • WangCZhuXFengWVerteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasmAm J Cancer Res201561273727073720
  • OkuYNishiyaNShitoTSmall molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancersFEBS Open Bio201551542549
  • JiaoSWangHShiZA peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancerCancer Cell201425216618024525233
  • MoroishiTHayashiTPanWWThe Hippo Pathway Kinases LATS1/2 Suppress Cancer ImmunityCell201616761525.e171539.e1727912060
  • MittendorfEAPhilipsAVMericbernstamFPD-L1 Expression in Triple-Negative Breast CancerCancer Immunol Res20142436137024764583
  • SchmidPCruzCBraitehFSAbstract 2986: atezolizumab in metastatic TNBC (mTNBC): long-term clinical outcomes and biomarker analysesCancer Res20177713 Suppl29862986
  • YeSEisinger-MathasonTSTargeting the Hippo pathway: clinical implications and therapeuticsPharmacol Res201510327027826678601