85
Views
9
CrossRef citations to date
0
Altmetric
Original Research

CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial–mesenchymal transition in osteosarcoma cells

, , , , &
Pages 3159-3166 | Published online: 28 May 2018

References

  • MirabelloLTroisiRJSavageSAOsteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results ProgramCancer200911571531154319197972
  • Kempf-BielackBBielackSSJürgensHOsteosarcoma relapse after combined modality therapy: an analysis of unselected patients in the cooperative Osteosarcoma Study Group (COSS)J Clin Oncol200523355956815659502
  • GoorinAMSchwartzentruberDJDevidasMPresurgical chemotherapy compared with immediate surgery and adjuvant chemotherapy for nonmetastatic osteosarcoma: Pediatric Oncology Group Study POG-8651J Clin Oncol20032181574158012697883
  • MeyersPAHellerGHealeyJChemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experienceJ Clin Oncol19921015151370176
  • MarkoTADiessnerBJSpectorLGPrevalence of metastasis at diagnosis of osteosarcoma: an international comparisonPediatr Blood Cancer20166361006101126929018
  • DuchmanKRGaoYMillerBJPrognostic factors for survival in patients with high-grade osteosarcoma using the Surveillance, Epidemiology, and End Results (SEER) Program databaseCancer Epidemiol201539459359926002013
  • PaxtonRJMooserGPandeHLeeTDShivelyJESequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene familyProc Natl Acad Sci U S A19878449209243469650
  • BlumenthalRDHansenHJGoldenbergDMInhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen)Cancer Res200565198809881716204051
  • CameronSde LongLMHazar-RethinamMFocal overexpression of CEACAM6 contributes to enhanced tumourigenesis in head and neck cancer via suppression of apoptosisMol Cancer2012117423021083
  • ChenJLiQAnYCEACAM6 induces epithelial-mesenchymal transition and mediates invasion and metastasis in pancreatic cancerInt J Oncol201343387788523857344
  • KimKSKimJTLeeSJOverexpression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in colorectal cancerClin Chim Acta2013415121922975528
  • TsangJYKwokYKChanKWExpression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in breast cancersBreast Cancer Res Treat2013142231132224186057
  • LitkouhiBLitkouhiBFlemingEOverexpression of CEACAM6 in borderline and invasive mucinous ovarian neoplasmsGynecol Oncol2008109223423918331757
  • IetaKTanakaFUtsunomiyaTKuwanoHMoriMCEACAM6 gene expression in intrahepatic cholangiocarcinomaBr J Cancer200695453254016868542
  • LiuKHeQLiaoGHanJIdentification of critical genes and gene interaction networks that mediate osteosarcoma metastasis to the lungsExp Ther Med20151051796180626640552
  • LiQYeLGuoWWangMHuangSPengXPHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/beta-catenin signaling pathwayJ Exp Clin Cancer Res20173618528645312
  • LiQYeLZhangXFZD8, a target of p53, promotes bone metastasis in prostate cancer by activating canonical Wnt/beta-catenin signalingCancer Lett201740216617628602974
  • LiQYeLGuoWWangMHuangSPengXOverexpression of TACC3 is correlated with tumor aggressiveness and poor prognosis in prostate cancerBiochem Biophys Res Commun2017486487287828336437
  • NiinakaYHaradaKFujimuroMSilencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasisCancer Res201070229483949320978190
  • KuespertKPilsSHauckCRCEACAMs: their role in physiology and pathophysiologyCurr Opin Cell Biol200618556557116919437
  • YokoyamaSChenCJNguyenTShivelyJERole of CEACAM1 isoforms in an in vivo model of mammary morphogenesis: mutational analysis of the cytoplasmic domain of CEACAM1-4S reveals key residues involved in lumen formationOncogene200726557637764617546042
  • HorstAKItoWDDabelsteinJCarcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivoJ Clin Invest200611661596160516680193
  • SingerBBScheffrahnIKammererRSuttorpNErgunSSlevogtHDeregulation of the CEACAM expression pattern causes undifferentiated cell growth in human lung adenocarcinoma cellsPLoS One201051e874720090913
  • KlaileEMullerMMKannichtCSingerBBLuckaLCEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migrationJ Cell Sci2005118Pt 235513552416291724
  • SingerBBKlaileEScheffrahnICEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytesEur J Immunol20053561949195915909305
  • MuenznerPRohdeMKneitzSHauckCRCEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cellsJ Cell Biol2005170582583616115956
  • JantscheffPTerraccianoLLowyAExpression of CEACAM6 in resectable colorectal cancer: a factor of independent prognostic significanceJ Clin Oncol200321193638364614512395
  • HongKPShinMHYoonSTherapeutic effect of anti CEACAM6 monoclonal antibody against lung adenocarcinoma by enhancing anoikis sensitivityBiomaterials201567324126204223
  • CortesEPChuTMWangJJHolyokeDWallaceHJMurphyGPCarcinoembryonic antigen in osteosarcomaJ Surg Oncol197793257265267237
  • YuHYuJRenYYangYXiaoXSerum CEACAM1 level is associated with diagnosis and prognosis in patients with osteosarcomaPLoS One2016114e015360127074014
  • Lewis-WambiJSCunliffeHEKimHRWillisALJordanVCOverexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cellsEur J Cancer200844121770177918614350
  • DuxburyMSItoHZinnerMJAshleySWWhangEECEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cellsOncogene200423246547314724575
  • HayEDAn overview of epithelio-mesenchymal transformationActa Anat (Basel)199515418208714286
  • KalluriRWeinbergRAThe basics of epithelial-mesenchymal transitionJ Clin Invest200911961420142819487818