Magnolol exerts anticancer activity in hepatocellular carcinoma cells through regulating endoplasmic reticulum stress-mediated apoptotic signaling

Ya-Dong Wang1 Department of General Surgery, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, People’s Republic of China, [email protected]

Xue-Jun Sun2 Department of General Surgery, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, People’s Republic of China

Wei-Jun Yang3 Department of General Surgery, The First People’s Hospital of Guiyang, Guiyang 550002, People’s Republic of China

Jing Li1 Department of General Surgery, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, People’s Republic of China, [email protected]

Jia-Jun Yin1 Department of General Surgery, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, People’s Republic of China, [email protected]Correspondence[email protected]

Pages 5219-5226 | Published online: 28 Aug 2018

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AltekruseSFMcGlynnKADickieLAKleinerDEHepatocellular carcinoma confirmation, treatment, and survival in surveillance, epidemiology, and end results registries, 1992–2008Hepatology201255247648221953588
PubMed Web of Science ®Google Scholar
ScudellariMDrug development: try and try againNature20145167529S4S625470198
PubMed Web of Science ®Google Scholar
MaYHendershotLMThe unfolding tale of the unfolded protein responseCell2001107782783011779459
PubMed Web of Science ®Google Scholar
BhatTAChaudharyAKKumarSEndoplasmic reticulummediated unfolded protein response and mitochondrial apoptosis in cancerBiochim Biophys Acta201718671586627988298
PubMed Web of Science ®Google Scholar
KoehnFECarterGTThe evolving role of natural products in drug discoveryNature Rev Drug Discov20054320622015729362
PubMed Web of Science ®Google Scholar
HuYWangSWuXChinese herbal medicine-derived compounds for cancer therapy: a focus on hepatocellular carcinomaJ Ethnopharmacol2013149360161223916858
PubMed Web of Science ®Google Scholar
LoYCTengCMChenCFChenCCHongCYMagnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidationBiochem Pharmacol19944735495538117323
PubMed Web of Science ®Google Scholar
ZhouYBiYYangCMagnolol induces apoptosis in MCF-7 human breast cancer cells through G2/M phase arrest and caspase-independent pathwayPharmazie201368975576224147344
PubMed Web of Science ®Google Scholar
TsaiJRChongIWChenYHMagnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cellsArch Pharm Res201437454855723943503
PubMed Web of Science ®Google Scholar
LiMZhangFWangXMagnolol inhibits growth of gallbladder cancer cells through the p53 pathwayCancer Sci2015106101341135026250568
PubMed Web of Science ®Google Scholar
KilkennyCBrowneWCuthillICEmersonMAltmanDGNC3Rs Reporting Guidelines Working GroupAnimal research: reporting in vivo experiments: the ARRIVE guidelinesJ Gene Med201012756156320607692
PubMed Web of Science ®Google Scholar
HanahanDWeinbergRAHallmarks of cancer: the next generationCell2011144564667421376230
PubMed Web of Science ®Google Scholar
LinSYLiuJDChangHCYehSDLinCHLeeWSMagnolol suppresses proliferation of cultured human colon and liver cancer cells by inhibiting DNA synthesis and activating apoptosisJ Cell Biochem200284353254411813258
PubMed Web of Science ®Google Scholar
GerlRVauxDLApoptosis in the development and treatment of cancerCarcinogenesis200526226327015375012
PubMed Web of Science ®Google Scholar
ElkholiRRenaultTTSerasingheMNChipukJEPutting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?Cancer Metab201421625621172
PubMedGoogle Scholar
HarrisMHThompsonCBThe role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeabilityCell Death Differ20007121182119111175255
PubMed Web of Science ®Google Scholar
FaitovaJKrekacDHrstkaRVojtesekBEndoplasmic reticulum stress and apoptosisCell Mol Biol Lett200611448850516977377
PubMed Web of Science ®Google Scholar
OyadomariSMoriMRoles of CHOP/GADD153 in endoplasmic reticulum stressCell Death Differ200411438138914685163
PubMed Web of Science ®Google Scholar

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