Prognostic significance of NANOG expression in solid tumors: a meta-analysis

References

• ChambersIColbyDRobertsonMFunctional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cellsCell2003113564365512787505
   PubMed Web of Science ®Google Scholar
• doDVUedaJMesserschmidtDMA genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivoGenes Dev201327121378139023788624
   PubMed Web of Science ®Google Scholar
• VisvaderJECells of origin in cancerNature2011469733031432221248838
   PubMed Web of Science ®Google Scholar
• WangTShigdarSGantierMPCancer stem cell targeted therapy: progress amid controversiesOncotarget2015642441914420626496035
   PubMedGoogle Scholar
• ChangBParkMJChoiSINANOG as an adverse predictive marker in advanced non-small cell lung cancer treated with platinum-based chemotherapyOnco Targets Ther2017104625463329033581
   PubMed Web of Science ®Google Scholar
• NagataTShimadaYSekineSKLF4 and NANOG are prognostic biomarkers for triple-negative breast cancerBreast Cancer201724232633527300169
   PubMed Web of Science ®Google Scholar
• XueYMYaoBWLiuZKExpression and clinical significance of NANOG in hepatocellular carcinomaJournal of Xi’an Jiaotong University2016375684688
   Google Scholar
• WangSFanHXuJZhaoEPrognostic implication of NOTCH1 in early stage oral squamous cell cancer with occult metastasesClin Oral Investig201822311311138
   Web of Science ®Google Scholar
• LiNDengWMaJPrognostic evaluation of Nanog, Oct4, Sox2, PCNA, Ki67 and E-cadherin expression in gastric cancerMedical Oncology201532119
   Web of Science ®Google Scholar
• HwangCCNiehSLaiCHA retrospective review of the prognostic value of ALDH-1, Bmi-1 and Nanog stem cell markers in esophageal squamous cell carcinomaPLoS One201498e10567625148045
   PubMed Web of Science ®Google Scholar
• MengHMZhengPWangXYOver-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancerCancer Biol Ther20109429530220026903
   PubMed Web of Science ®Google Scholar
• GaoSPanYSongLNanog Predicts Poor Prognosis in Human Pancreatic Cancer and Is Downregulated by QingyihuaJi Formula in Pancreatic Cancer Stem CellsEvid Based Complement Alternat Med201620167028289927829864
   PubMed Web of Science ®Google Scholar
• Kenda ŠusterNFrković GrazioSVirant-KlunIVerdenikISmrkoljŠCancer Stem Cell-Related Marker NANOG Expression in Ovarian Serous Tumors: A Clinicopathological Study of 159 CasesInt J Gynecol Cancer20172792006201328906309
   PubMed Web of Science ®Google Scholar
• LuoWLiSPengBEmbryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correference are not relations with Epithelial-Mesenchymal Transition in Nasopharyngeal CarcinomaPlos One201382e5632423424657
   PubMed Web of Science ®Google Scholar
• RavindranGSawantSSHagueAKingsleyKDevarajHAssociation of differential β-catenin expression with Oct-4 and Nanog in oral squamous cell carcinoma and their correlation with clinicopathological factors and prognosisHead Neck201537798299324700702
   PubMed Web of Science ®Google Scholar
• VazMAMartinezJCDevesaJMPrognostic value of stem cell quantification in stage II colon cancerPLoS One201492e8848024586330
   PubMed Web of Science ®Google Scholar
• StangACritical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analysesEur J Epidemiol201025960360520652370
   PubMed Web of Science ®Google Scholar
• TierneyJFStewartLAGhersiDBurdettSSydesMRPractical methods for incorporating summary time-to-event data into meta-analysisTrials200781617555582
   PubMed Web of Science ®Google Scholar
• XuWWangYQiXPrognostic factors of palatal mucoepidermoid carcinoma: a retrospective analysis based on a double-center studySci Rep201774390728262804
   PubMed Web of Science ®Google Scholar
• ElsirTEdqvistPHCarlsonJA study of embryonic stem cell-related proteins in human astrocytomas: identification of Nanog as a predictor of survivalInt J Cancer201413451123113124037901
   PubMed Web of Science ®Google Scholar
• SiuMKWongESKongDSStem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancersOncogene201332303500350922945654
   PubMed Web of Science ®Google Scholar
• LeeMNamEJKimSWPrognostic impact of the cancer stem cell-related marker NANOG in ovarian serous carcinomaInt J Gynecol Cancer20122291489149623095773
   PubMed Web of Science ®Google Scholar
• LiXJZhaoYFLiMXExpression of Nanog and its prognostic significance in esophageal squamous cell carcinomaChinese Journal of Cancer Prevention and Treatment2014212419621965
   Google Scholar
• LuYZhuHShanHKnockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cellsCancer Lett2013340111312323872274
   PubMed Web of Science ®Google Scholar
• YinXLiYWZhangBHCoexpression of stemness factors Oct4 and Nanog predict liver resectionAnn Surg Oncol20121992877288722461131
   PubMed Web of Science ®Google Scholar
• LinTDingYQLiJMOverexpression of Nanog protein is associated with poor prognosis in gastric adenocarcinomaMed Oncol201229287888521336986
   PubMed Web of Science ®Google Scholar
• MatsuokaJYashiroMSakuraiKRole of the stemness factors sox2, oct3/4, and nanog in gastric carcinomaJ Surg Res2012174113013521227461
   PubMed Web of Science ®Google Scholar
• LeeHJKangYHLeeJSPositive expression of NANOG, mutant p53, and CD44 is directly associated with clinicopathological features and poor prognosis of oral squamous cell carcinomaBMC Oral Health201515115326626427
   PubMed Web of Science ®Google Scholar
• ChiouSHYuCCHuangCYPositive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinomaClin Cancer Res200814134085409518593985
   PubMed Web of Science ®Google Scholar
• JinCZhangXSunMClinical implications of the coexpression of SRC1 and NANOG in HER-2-overexpressing breast cancersOnco Targets Ther201695483548827660465
   PubMed Web of Science ®Google Scholar
• NagataTShimadaYSekineSPrognostic significance of NANOG and KLF4 for breast cancerBreast Cancer20142119610122528804
   PubMed Web of Science ®Google Scholar
• ParkEParkSYSunPLPrognostic significance of stem cell-related marker expression and its correlation with histologic subtypes in lung adenocarcinomaOncotarget2016727425024251227285762
   PubMedGoogle Scholar
• LuoMQPuQCaoYLRelationship between effect of GP regimen prognostic significance and Nanog expression in advanced lung cancerCancer Research and Clinic2013259609611
   Google Scholar
• LiXQYangXLZhangGNuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancerJ Transl Med201311111423648139
   PubMed Web of Science ®Google Scholar
• RodriguesMXavierFCAAndradeNPPrognostic implications of CD44, NANOG, OCT4, and BMI1 expression in tongue squamous cell carcinomaHead Neck2018115
   Google Scholar
• KimH-MKangY-HByunJ-HMidkine and NANOG Have Similar Immunohistochemical Expression Patterns and Contribute Equally to an Adverse Prognosis of Oral Squamous Cell CarcinomaInt J Mol Sci201718112339
   Web of Science ®Google Scholar
• WangHJyHSwLExpression of stem cell related transcription factors 3, high-mobility groupbox1, and stem cell markers Nanog and their significance in cervical cancerMedical Journal of Wuhan University2018393350355
   Google Scholar
• ZhangYMFanLXCaiYQNanog, Sox2 and TFF3 expression and their relationship with the prognosis of intestinal type gastric cancerOncology Progress201816017376
   Google Scholar
• OuyangXWFengTCZhangSRelationship between expressions of cancer suppressor gene Merlin and stem cell marker Nanog in hepatocellular carcinoma and the significanceChinese Journal of General Surgery2016250710111016
   Google Scholar
• SiegelRLMillerKDJemalACancer statistics, 2018CA: A Cancer Journal for Clinicians201868173029313949
   PubMed Web of Science ®Google Scholar
• HyslopLStojkovicMArmstrongLDownregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineagesStem Cells20052381035104315983365
   PubMed Web of Science ®Google Scholar
• Iv Santaliz-RuizLEXieXOldMTeknosTNPanQEmerging role of nanog in tumorigenesis and cancer stem cellsInt J Cancer2014135122741274824375318
   PubMed Web of Science ®Google Scholar
• Gawlik-RzemieniewskaNBednarekIThe role of NANOG transcriptional factor in the development of malignant phenotype of cancer cellsCancer Biol Ther201617111026618281
   PubMed Web of Science ®Google Scholar
• RobitschekEMaoC-PPengSHungC-FWuTCAbstract 448: The role of the Nanog transcription factor in tumor immune escapeCancer Res20157515448
   Web of Science ®Google Scholar
• HuangCEYuCCHuFWChouMYTsaiLLEnhanced chemosen-sitivity by targeting Nanog in head and neck squamous cell carcinomasInt J Mol Sci2014159149351494825158233
   PubMed Web of Science ®Google Scholar
• TsaiLLYuCCChangYCYuCHChouMYMarkedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinomaJ Oral Pathol Med201140862162821342274
   PubMed Web of Science ®Google Scholar
• YangLZhangXZhangMIncreased Nanog expression promotes tumor development and Cisplatin resistance in human esophageal cancer cellsCell Physiol Biochem201230494395223221432
   PubMedGoogle Scholar
• WongOGCheungANStem cell transcription factor NANOG in cancers – is eternal youth a curse?Expert Opin Ther Targets201620440741726634876
   PubMed Web of Science ®Google Scholar
• RadSMBamdadTSadeghizadehMTranscription factor decoy against stem cells master regulators, Nanog and Oct-4: a possible approach for differentiation therapyTumour Biol20153642621262925464862
   PubMedGoogle Scholar
• DingYYuAQLiCLAqYClLTALEN-mediated Nanog disruption results in less invasiveness, more chemosensitivity and reversal of EMT in Hela cellsOncotarget20145188393840125245189
   PubMedGoogle Scholar
• KawamuraNNimuraKNaganoHCRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cellsOncotarget2015626223612237426087476
   PubMedGoogle Scholar
• MattooARZhangJEspinozaLAJessupJMInhibition of NANOG/NANOGP8 downregulates MCL-1 in colorectal cancer cells and enhances the therapeutic efficacy of BH3 mimeticsClin Cancer Res201420215446545525208882
   PubMed Web of Science ®Google Scholar