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Original Research

Identification of driver genes associated with chemotherapy resistance of Ewing’s sarcoma

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Pages 6947-6956 | Published online: 15 Oct 2018

References

  • ObataHUedaTKawaiAClinical outcome of patients with Ewing sarcoma family of tumors of bone in Japan: the Japanese Musculoskeletal Oncology Group cooperative studyCancer2007109476777517238190
  • BöllingTHardesJDirksenUManagement of bone tumours in paediatric oncologyClin Oncol20132511926
  • SchaeferKLEisenacherMBraunYMicroarray analysis of Ewing’s sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapyEur J Cancer200844569970918294840
  • BiswasBBakhshiSManagement of Ewing sarcoma family of tumors: Current scenario and unmet needWorld J Orthop20167952753827672565
  • HayashiMChuDMeyerCFHighly personalized detection of minimal Ewing sarcoma disease burden from plasma tumor DNACancer2016122193015302327351911
  • GasparNHawkinsDSDirksenUEwing Sarcoma: Current Management and Future Approaches Through CollaborationJ Clin Oncol201533273036304626304893
  • SubbiahVKurzrockREwing’s sarcoma: overcoming the therapeutic plateauDiscov Med2012137340541522742646
  • PaulussenMAhrensSCraftAWEwing’s tumors with primary lung metastases: survival analysis of 114 (European Intergroup) Cooperative Ewing’s Sarcoma Studies patientsJ Clin Oncol1998169304430529738574
  • BacciGFerrariSLonghiATherapy and survival after recurrence of Ewing’s tumors: the Rizzoli experience in 195 patients treated with adjuvant and neoadjuvant chemotherapy from 1979 to 1997Ann Oncol200314111654165914581274
  • FuJJiangHWuCJiangYXiaoLTianYOvercoming cetuximab resistance in Ewing’s sarcoma by inhibiting lactate dehydrogenase-AMol Med Rep2016141995100127222229
  • ScotlandiKRemondiniDCastellaniGOvercoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcomeJ Clin Oncol200927132209221619307502
  • SavolaSKlamiAMyllykangasSHigh Expression of Complement Component 5 (C5) at Tumor Site Associates with Superior Survival in Ewing’s Sarcoma Family of Tumour PatientsISRN Oncol2011201116871222084725
  • GotterALSuppaCEmanuelBSMammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factorsJ Mol Biol20073661365217141802
  • FuALeadererDZhengTHoffmanAEStevensRGZhuYGenetic and epigenetic associations of circadian gene TIMELESS and breast cancer riskMol Carcinog2012511292392922006848
  • DongHClaffeyKPBrockeSEpsteinPMExpression of phosphodiesterase 6 (PDE6) in human breast cancer cellsSpringerplus2013268024683528
  • YoshidaKSatoMHaseTTIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survivalCancer Sci2013104217117723173913
  • ChiangYTGoutPWCollinsCCWangYProstate cancer metastasis-driving genes: hurdles and potential approaches in their identificationAsian J Androl201416454554824589457
  • ElgoharyNPellegrinoRNeumannOProtumorigenic role of Timeless in hepatocellular carcinomaInt J Oncol201546259760625405317
  • SchepelerTLamyPHvidbergVA high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage responseOncogene201332313577358622926521
  • ChiLZouYQinLTIMELESS contributes to the progression of breast cancer through activation of MYCBreast Cancer Res20171915328464854
  • YoungLMMarzioAPerez-DuranPTIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage ResponseCell Rep201513345145926456830
  • LiuSLLinHXLinCYTIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transitionCancer Lett201740211713028583847
  • YangXWoodPAHrusheskyWJMammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint controlJ Biol Chem201028553030303419996108
  • KosovaAAKhodyrevaSNLavrikOIRole of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in DNA RepairBiochemistry201782664365428601074
  • ColellAGreenDRRicciJENovel roles for GAPDH in cell death and carcinogenesisCell Death Differ200916121573158119779498
  • SheokandNMalhotraHKumarSMoonlighting cell-surface GAPDH recruits apotransferrin to effect iron egress from mammalian cellsJ Cell Sci2014127Pt 194279429125074810
  • ZhengLRoederRGLuoYS phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key componentCell2003114225526612887926
  • KimSLeeJKimJRegulation of oncogenic transcription factor hTAF(II)68-TEC activity by human glyceraldehyde-3-phosphate dehydrogenase (GAPDH)Biochem J2007404219720617302560
  • HaradaNYasunagaRHigashimuraYGlyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cellsJ Biol Chem200728231226512266117553795
  • DemarseNAPonnusamySSpicerEKDirect binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradationJ Mol Biol2009394478980319800890
  • KrynetskiEYKrynetskaiaNFGalloAEMurtiKGEvansWEA novel protein complex distinct from mismatch repair binds thioguanylated DNAMol Pharmacol200159236737411160874
  • AsteritiIAGiubettiniMLaviaPGuarguagliniGAurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forcesMol Cancer20111013122011530
  • BarrARGergelyFAurora-A: the maker and breaker of spindle polesJ Cell Sci2007120Pt 172987299617715155
  • MarumotoTZhangDSayaHAurora-A – a guardian of polesNat Rev Cancer200551425015630414
  • FuJBianMJiangQZhangCRoles of Aurora kinases in mitosis and tumorigenesisMol Cancer Res20075111017259342
  • SchvartzmanJMSotilloRBenezraRMitotic chromosomal instability and cancer: mouse modelling of the human diseaseNat Rev Cancer201010210211520094045
  • TongTZhongYKongJOverexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinomaClin Cancer Res200410217304731015534106
  • LandenCNLinYGImmaneniAOverexpression of the centrosomal protein Aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patientsClin Cancer Res200713144098410417634535
  • LinY-CHourT-CTsaiY-CPreliminary evidence of polymorphisms of cell cycle regulatory genes and their roles in urinary tract urothelial cancer susceptibility and prognosis in a Taiwan populationUrol Oncol2017359543.e7543.e16
  • RoyceMEXiaWSahinAASTK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosisCancer20041001121914692019
  • UmmanniRMannspergerHASonntagJEvaluation of reverse phase protein array (RPPA)-based pathway-activation profiling in 84 non-small cell lung cancer (NSCLC) cell lines as platform for cancer proteomics and biomarker discoveryBiochim Biophys Acta20141844595095924361481
  • ZhengXChiJZhiJAurora-A-mediated phosphorylation of LKB1 compromises LKB1/AMPK signaling axis to facilitate NSCLC growth and migrationOncogene201837450251128967900
  • ChenMWHuaKTKaoHJH3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAMCancer Res201070207830784020940408
  • HsiaoSMChenMWChenCAThe H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial CancerAnn Surg Oncol201522Suppl 315561565
  • WeiLChiuDKTsangFHHistone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3J Hepatol201767475876928532996
  • ZhongXChenXGuanXOverexpression of G9a and MCM7 in oesophageal squamous cell carcinoma is associated with poor prognosisHistopathology201566219220024805087
  • ChenMWHuaKTKaoHJH3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAMCancer Res201070207830784020940408
  • KimYKimYSKimDEBIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species productionAutophagy20139122126213924322755
  • CascielloFWindlochKGannonFLeeJSFunctional Role of G9a Histone Methyltransferase in CancerFront Immunol2015648726441991
  • LinXHuangYZouYChenXMaXDepletion of G9a gene induces cell apoptosis in human gastric carcinomaOncol Rep20163553041304927081761
  • ChaSTTanCTChangCCG9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathwayNat Cell Biol2016189993100527525719
  • LuoCWWangJYHungWCG9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage responseRadiother Oncol2017124339540228351524