Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene

References

• Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol. 2006;24(14):2137–2150. doi:10.1200/JCO.2005.05.2308
   PubMed Web of Science ®Google Scholar
• Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69–90. doi:10.3322/caac.20107
   PubMed Web of Science ®Google Scholar
• Sitarz R, Skierucha M, Mielko J, Offerhaus J, Maciejewski R, Polkowski W. Gastric cancer: epidemiology, prevention, classification, and treatment. Cancer Manag Res. 2018;10:239–248. doi:10.2147/CMAR.S149619
   PubMed Web of Science ®Google Scholar
• Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74–108. doi:10.3322/canjclin.55.2.74
   PubMed Web of Science ®Google Scholar
• Cunningham D, Allum WH, Stenning SP, et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med. 2006;355:11–20. doi:10.1056/NEJMoa055531
   PubMed Web of Science ®Google Scholar
• Yano H, Mizoguchi A, Fukuda K, et al. The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase. Cancer Res. 1994;54:448–454.
   PubMed Web of Science ®Google Scholar
• Chia J-S, Du J-L, Hsu W-B, Sun A, Chiang C-P, Wang W-B. Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail tien-hsien liquid. BMC Cancer. 2010;10(1):175. doi:10.1186/1471-2407-10-175
   PubMedGoogle Scholar
• Ji Q, Liu X, Fu X, et al. Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/β-catenin signal pathway. PLoS One. 2013;8(11):e78700. doi:10.1371/journal.pone.0078700
   PubMed Web of Science ®Google Scholar
• Khazal K, Simon L, Odemuyiwa S, Hill D, Grubbs C. Abstract P6-09-08: withania somnifera extract inhibits invasion and metastasis of MDA-MB-231 cells by inhibiting CCL2 and CD44 high/CD24low stem cells. Am Assoc Cancer Res. 2013;P6-09-08-P6-09–08. doi:10.1158/0008-5472.SABCS13-P6-09-08
   Google Scholar
• Wang Z, Ravula R, Cao M, Chow M, Huang Y. Transporter-mediated multidrug resistance and its modulation by chinese medicines and other herbal products. Curr Drug Discov Technol. 2010;999(999):1–13. doi:10.2174/1570210201561361638
   Google Scholar
• Lee I-A, Lee JH, Baek N-I, Kim D-H. Antihyperlipidemic Effect of crocin isolated from the fructus of gardenia jasminoides and its metabolite crocetin. Biol Pharm Bull. 2005;28:2106–2110. doi:10.1248/bpb.28.2106
   PubMed Web of Science ®Google Scholar
• Li J, Lei H, Cao L, Mi Y-N, Li S, Cao Y-X. Crocin alleviates coronary atherosclerosis via inhibiting lipid synthesis and inducing M2 macrophage polarization. Int Immunopharmacol. 2018;55:120–127. doi:10.1016/j.intimp.2017.11.037
   PubMed Web of Science ®Google Scholar
• Yosri H, Elkashef WF, Said E, Gameil NM. Crocin modulates IL-4/IL-13 signaling and ameliorates experimentally induced allergic airway asthma in a murine model. Int Immunopharmacol. 2017;50:305–312. doi:10.1016/j.intimp.2017.07.012
   PubMed Web of Science ®Google Scholar
• Abou-Hany HO, Atef H, Said E, Elkashef HA, Salem HA. Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic rats. Chem Biol Interact. 2018;284:90–100. doi:10.1016/j.cbi.2018.02.001
   PubMed Web of Science ®Google Scholar
• Noureini SK, Wink M. Antiproliferative effects of crocin in HepG2 cells by telomerase inhibition and hTERT down-regulation. Asian Pac J Cancer Prev. 2012;13:2305–2309. doi:10.7314/APJCP.2012.13.5.2305
   PubMedGoogle Scholar
• Puthanveettil S, Kandel E. Molecular mechanisms for the initiation and maintenance of long-term memory storage. In: Two Faces of Evil: Cancer and Neurodegeneration. Berlin, Heidelberg: Springer; 2011:143–160. doi:10.1007/978-3-642-16602-0_13
   Google Scholar
• Garc-Olmo DC, Riese HH, Escribano J, et al. Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron (Crocus sativus L.): an Experimental Study in the Rat. Nutr Cancer. 1999;35:120–126. doi:10.1207/S15327914NC352_4
   PubMed Web of Science ®Google Scholar
• Sajjadi M, Bathaie Z. Comparative study on the preventive effect of saffron carotenoids, crocin and crocetin, in NMU-induced breast cancer in rats. Cell J. 2017;19:94–101. doi:10.22074/CELLJ.2016.3901
   PubMed Web of Science ®Google Scholar
• Luo YS, Yu P, Zhao J, et al. Analysis of the pathogenesisi and anti-proliferation mechanisms of crocin in human gastric carcinoma cell. Int J Clin Exp Pathol. 2020;13(5):912.
   PubMed Web of Science ®Google Scholar
• Hansen HG, Hansen HG. Celigo-based cell-counting and viability assay for mammalian cells. Protoc Exch. 2016. doi:10.1038/protex.2016.038
   Google Scholar
• Li D-Q, Wang L, Fei F, et al. Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry. Proteomics. 2006;6(11):3352–3368. doi:10.1002/pmic.200500617
   PubMed Web of Science ®Google Scholar
• Lomnytska MI, Becker S, Bodin I, et al. Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value. Br J Cancer. 2011;104:110–119. doi:10.1038/sj.bjc.6605992
   PubMed Web of Science ®Google Scholar
• Yang R, Zheng G, Ren D, et al. The clinical significance and biological function of tropomyosin 4 in colon cancer. Biomed Pharmacother. 2018;101:1–7. doi:10.1016/j.biopha.2018.01.166
   PubMed Web of Science ®Google Scholar
• Mollazadeh H, Emami SA, Hosseinzadeh H. Razi’s Al-Hawi and saffron (Crocus sativus): a review., Iran. J Basic Med Sci. 2015;18:1153–1166.
   Google Scholar
• Imenshahidi M, Hosseinzadeh H, Javadpour Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and Crocin, in normotensive and hypertensive rats. Phyther Res. 2009. doi:10.1002/ptr.3044
   Web of Science ®Google Scholar
• Vahdati Hassani F, Naseri V, Razavi B, Mehri S, Abnous K, Hosseinzadeh H. Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus. DARU J Pharm Sci. 2014;22:16. doi:10.1186/2008-2231-22-16
   Web of Science ®Google Scholar
• Rastgoo M, Hosseinzadeh H, Alavizadeh H, Abbasi A, Ayati Z, Jaafari M. Antitumor activity of PEGylated nanoliposomes containing crocin in mice bearing C26 colon carcinoma. Planta Med. 2013;79:447–451. doi:10.1055/s-0032-1328363
   PubMed Web of Science ®Google Scholar
• Mollaei H, Safaralizadeh R, Babaei E, Abedini MR, Hoshyar R. The anti-proliferative and apoptotic effects of crocin on chemosensitive and chemoresistant cervical cancer cells. Biomed Pharmacother. 2017;94:307–316. doi:10.1016/j.biopha.2017.07.052
   PubMed Web of Science ®Google Scholar
• Hardwick JS, Yang Y, Zhang C, et al. Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling. Mol Cancer Ther. 2005;4:413–425. doi:10.1158/1535-7163.MCT-04-0209
   PubMed Web of Science ®Google Scholar
• Tang H-Y, Beer LA, Tanyi JL, Zhang R, Liu Q, Speicher DW. Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer. J Proteom. 2013;89:165–178. doi:10.1016/j.jprot.2013.06.016
   PubMed Web of Science ®Google Scholar
• Dube DK, Dube S, Abbott L, Alshiekh-Nasany R, Mitschow C, Poiesz BJ. Cloning, sequencing, and the expression of the elusive sarcomeric TPM4 α isoform in humans. Mol Biol Int. 2016;2016:1–11. doi:10.1155/2016/3105478
   Google Scholar
• Guven K, Gunning P, Fath T. TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses. Bioarchitecture. 2011;1(6):284–289. doi:10.4161/bioa.1.6.19336
   PubMedGoogle Scholar
• Lawrence B, Perez-Atayde A, Hibbard MK, et al. TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. Am J Pathol. 2000;157:377–384. doi:10.1016/S0002-9440(10)64550-6
   PubMed Web of Science ®Google Scholar