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Original Research

The Significance of HOXC11 and LSH in Survival Prediction in Gastric Adenocarcinoma

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Pages 1517-1529 | Published online: 01 Mar 2021

References

  • Ajani JA, Lee J, Sano T, Janjigian YY, Fan D, Song S. Gastric adenocarcinoma. Nat Rev Dis Primers. 2017;3:17036.
  • Olsen S, Jin L, Fields RC, Yan Y, Nalbantoglu I. Tumor budding in intestinal-type gastric adenocarcinoma is associated with nodal metastasis and recurrence. Hum Pathol. 2017;68:26–33. doi:10.1016/j.humpath.2017.03.021
  • Torre LA, Siegel RL, Ward EM, Jemal A. Global cancer incidence and mortality rates and trends—an update. Cancer Epidemiol Biomarkers Prevent. 2016;25(1):16–27. doi:10.1158/1055-9965.EPI-15-0578
  • Corso S, Giordano S. How can gastric cancer molecular profiling guide future therapies? Trends Mol Med. 2016;22(7):534–544. doi:10.1016/j.molmed.2016.05.004
  • Sung H, Yang HH, Zhang H, et al. Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers. Int J Epidemiol. 2015;44(4):1341–1352. doi:10.1093/ije/dyv050
  • Burglin TR, Affolter M. Homeodomain proteins: an update. Chromosoma. 2016;125(3):497–521.
  • Fongang B, Kong F, Negi S, Braun W, Kudlicki A. A conserved structural signature of the homeobox coding DNA in HOX genes. Sci Rep. 2016;6(1):35415. doi:10.1038/srep35415
  • Procino A, Cillo C. The HOX genes network in metabolic diseases.. Cell Biol Int. 2013;37(11):1145–1148. doi:10.1002/cbin.10145
  • McIlroy M, McCartan D, Early S, et al. Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected]. Cancer Res. 2010;70(4):1585–1594. doi:10.1158/0008-5472.CAN-09-3713
  • Liu Y-J, Zhu Y, Yuan H-X, Zhang J-P, Guo J-M, Lin Z-M. Overexpression of HOXC11 homeobox gene in clear cell renal cell carcinoma induces cellular proliferation and is associated with poor prognosis. Tumour Biol. 2015;36(4):2821–2829. doi:10.1007/s13277-014-2909-6
  • Saha SS, Chowdhury RR, Mondal NR, Roy S, Sengupta S. Expression signatures of HOX cluster genes in cervical cancer pathogenesis: impact of human papillomavirus type 16 oncoprotein E7. Oncotarget. 2017;8(22):36591–36602. doi:10.18632/oncotarget.16619
  • Lungu C, Muegge K, Jeltsch A, Jurkowska RZ. An ATPase-deficient variant of the SNF2 family member HELLS shows altered dynamics at pericentromeric heterochromatin. J Mol Biol. 2015;427(10):1903–1915. doi:10.1016/j.jmb.2015.03.014
  • Huang J, et al. Lsh, an epigenetic guardian of repetitive elements. Nucleic Acids Res. 2004;32(17):5019–5028. doi:10.1093/nar/gkh821
  • Choi YJ, Yoo NJ, Lee SH. Mutation of HELLS, a chromatin remodeling gene, gastric and colorectal cancers. Pathol Oncol Res. 2015;21(3):851–852. doi:10.1007/s12253-014-9862-y
  • Termanis A, Torrea N, Culley J, Kerr A, Ramsahoye B, Stancheva I. The SNF2 family ATPase LSH promotes cell-autonomous de novo DNA methylation in somatic cells. Nucleic Acids Res. 2016;44(16):7592–7604. doi:10.1093/nar/gkw424
  • Geiman TM, Durum SK, Muegge K. Characterization of gene expression, genomic structure, and chromosomal localization ofhells (Lsh). Genomics. 1998;54(3):477–483. doi:10.1006/geno.1998.5557
  • Mjelle R, Hegre SA, Aas PA, et al. Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair (Amst). 2015;30:53–67. doi:10.1016/j.dnarep.2015.03.007
  • Burrage J, Termanis A, Geissner A, Myant K, Gordon K, Stancheva I. The SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells. J Cell Sci. 2012;125(22):5524–5534. doi:10.1242/jcs.111252
  • Jiang Y, Mao C, Yang R, et al. EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes. Theranostics. 2017;7(13):3293–3305. doi:10.7150/thno.19988
  • Wang K, Yuen ST, Xu J, et al. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Nat Genet. 2014;46(6):573–582. doi:10.1038/ng.2983
  • Jia J, Shi Y, Chen L, et al. Decrease in lymphoid specific helicase and 5-hydroxymethylcytosine is associated with metastasis and genome instability. Theranostics. 2017;7(16):3920–3932. doi:10.7150/thno.21389
  • Liu S, Tao Y-G. Chromatin remodeling factor LSH affects fumarate hydratase as a cancer driver. Chin J Cancer. 2016;35(1):72. doi:10.1186/s40880-016-0138-7
  • He X, Yan B, Liu S, et al. Chromatin remodeling factor lsh drives cancer progression by suppressing the activity of fumarate hydratase. Cancer Res. 2016;76(19):5743–5755. doi:10.1158/0008-5472.CAN-16-0268
  • Law C-T, Wei L, Tsang FH-C, et al. HELLS regulates chromatin remodeling and epigenetic silencing of multiple tumor suppressor genes in human hepatocellular carcinoma. Hepatology. 2019;69(5):2013–2030. doi:10.1002/hep.30414
  • Wang R, Shi Y, Chen L, et al. The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH. Sci Rep. 2016;5(1):17826. doi:10.1038/srep17826
  • Jiang Y, He Y, Liu S, Tao Y. Chromatin remodeling factor lymphoid-specific helicase inhibits ferroptosis through lipid metabolic genes in lung cancer progression. Chin J Cancer. 2017;36(1):82. doi:10.1186/s40880-017-0248-x
  • Chen D, Maruschke M, Hakenberg O, Zimmermann W, Stief CG, Buchner A. TOP2A, HELLS, ATAD2, and TET3 are novel prognostic markers in renal cell carcinoma. Urology. 2017;102:265.e261-265.e267. doi:10.1016/j.urology.2016.12.050
  • Xiao D, Huang J, Pan Y, et al. Chromatin remodeling factor LSH is upregulated by the LRP6-GSK3β-E2F1 axis linking reversely with survival in gliomas. Theranostics. 2017;7(1):132–143. doi:10.7150/thno.17032
  • Wu SC, Benavente CA. Chromatin remodeling protein HELLS is upregulated by inactivation of the RB-E2F pathway and is nonessential for osteosarcoma tumorigenesis. Oncotarget. 2018;9(66):32580–32592. doi:10.18632/oncotarget.25953
  • Xi S, Zhu H, Xu H, Schmidtmann A, Geiman TM, Muegge K. Lsh controls Hox gene silencing during development. Proc Natl Acad Sci U S A. 2007;104(36):14366–14371. doi:10.1073/pnas.0703669104
  • Deng J, Zhang R, Pan Y, et al. Comparison of the staging of regional lymph nodes using the sixth and seventh editions of the tumor-node-metastasis (TNM) classification system for the evaluation of overall survival in gastric cancer patients: findings of a case-control analysis involving a single institution in China.. Surgery. 2014;156(1):64–74. doi:10.1016/j.surg.2014.03.020
  • Du Y-B, Dong B, Shen L-Y, et al. The survival predictive significance of HOXC6 and HOXC8 in esophageal squamous cell carcinoma. J Surg Res. 2014;188(2):442–450. doi:10.1016/j.jss.2014.01.017
  • Holland PWH. Evolution of homeobox genes. Wiley Interdisciplinary Rev. 2013;2(1):31–45. doi:10.1002/wdev.78
  • Shah N, Sukumar S. The Hox genes and their roles in oncogenesis. Nat Rev Cancer. 2010;10(5):361–371. doi:10.1038/nrc2826
  • Yano M, Ouchida M, Shigematsu H, et al. Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer. Int J Cancer. 2004;112(1):8–13. doi:10.1002/ijc.20407
  • Ren J, Finney R, Ni K, Cam M, Muegge K. The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors. Epigenetics. 2019;14(3):277–293. doi:10.1080/15592294.2019.1582275
  • Yu W, McIntosh C, Lister R, et al. Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways. Genome Res. 2014;24(10):1613–1623. doi:10.1101/gr.172015.114
  • Walsh CA, Bolger JC, Byrne C, et al. Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis. Cancer Res. 2014;74(9):2533–2544. doi:10.1158/0008-5472.CAN-13-2133
  • Bantignies F, Roure V, Comet I, et al. Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila. Cell. 2011;144(2):214–226. doi:10.1016/j.cell.2010.12.026
  • Tao Y, Xi S, Briones V, Muegge K, Freitag M. Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation. PLoS One. 2010;5(2):e9163. doi:10.1371/journal.pone.0009163
  • Joo MK, Park -J-J, Chun HJ. Impact of homeobox genes in gastrointestinal cancer. World J Gastroenterol. 2016;22(37):8247–8256. doi:10.3748/wjg.v22.i37.8247
  • Bhatlekar S, Fields JZ, Boman BM. HOX genes and their role in the development of human cancers. J Mol Med. 2014;92(8):811–823. doi:10.1007/s00109-014-1181-y
  • deBlacam C, Byrne C, Hughes E, et al. HOXC11–SRC-1 regulation of S100beta in cutaneous melanoma: new targets for the kinase inhibitor dasatinib. Br J Cancer. 2011;105(1):118–123. doi:10.1038/bjc.2011.193