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OncoTargets and Therapy Volume 14, 2021 - Issue
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Original Research

Daam1 Overexpression Promotes Gastric Cancer Progression and Regulates ERK and AKT Signaling Pathways

Yue ZhangDepartment of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence[email protected]
,
Xue BaiDepartment of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China
,
Yi ZhangDepartment of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China
&
Yan LiDepartment of Gerontology and Geriatrics, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China
Pages 4609-4619 | Published online: 27 Aug 2021

References

  • Van Cutsem E, Sagaert X, Topal B, Haustermans K, Prenen H. Gastric cancer. Lancet. 2016;388(10060):2654–2664. doi:10.1016/S0140-6736(16)30354-3
  • Siegel RL, Miller KD, Jemal A. Cancer statistics, 2017. CA Cancer J Clin. 2017;67:7–30. doi:10.3322/caac.21387
  • Yoon C, Cho S-J, Aksoy BA, et al. Chemotherapy resistance in diffuse-type gastric adenocarcinoma is mediated by RhoA activation in cancer stem-like cells. Clin Cancer Res. 2016;22(4):971–983. doi:10.1158/1078-0432.CCR-15-1356
  • Du J, Fu L, Hao J, Lin X, Dong Q. Rab11a is overexpressed in gastric cancer and regulates FAK/AKT signaling. J Oncol. 2020;2020:3494396. doi:10.1155/2020/3494396
  • Aspenstrom P, Richnau N, Johansson AS. The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics. Exp Cell Res. 2006;312:2180–2194. doi:10.1016/j.yexcr.2006.03.013
  • Hoffmann AK, Naj X, Linder S. Daam1 is a regulator of filopodia formation and phagocytic uptake of Borrelia burgdorferi by primary human macrophages. FASEB J. 2014;28:3075–3089. doi:10.1096/fj.13-247049
  • Luo W, Lieu ZZ, Manser E, Bershadsky AD, Sheetz MP. Formin DAAM1 organizes actin filaments in the cytoplasmic nodal actin network. PLoS One. 2016;11:e0163915. doi:10.1371/journal.pone.0163915
  • Nishimura T, Ito S, Saito H, et al. DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility. J Cell Biol. 2016;215:559–573. doi:10.1083/jcb.201603107
  • Mei J, Xu B, Hao L, et al. Overexpressed DAAM1 correlates with metastasis and predicts poor prognosis in breast cancer. Pathol Res Pract. 2020;216:152736. doi:10.1016/j.prp.2019.152736
  • Xiong H, Yan T, Zhang W, et al. miR-613 inhibits cell migration and invasion by downregulating Daam1 in triple-negative breast cancer. Cell Signal. 2018;44:33–42. doi:10.1016/j.cellsig.2018.01.013
  • Liu G, Yan T, Li X, et al. Daam1 activates RhoA to regulate Wnt5ainduced glioblastoma cell invasion. Oncol Rep. 2018;39:465–472.
  • Mei J, Huang Y, Hao L, et al. DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p. Pathol Res Pract. 2019;215:152452. doi:10.1016/j.prp.2019.152452
  • Rodriguez-Hernandez I, Maiques O, Kohlhammer L, et al. WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion. Nat Commun. 2020;11:5315. doi:10.1038/s41467-020-18951-2
  • Guerra F, Arbini AA, Moro L. Mitochondria and cancer chemoresistance. Biochim Biophys Acta. 2017;1858:686–699. doi:10.1016/j.bbabio.2017.01.012
  • Kim JS, Lee JM, Chwae YJ, et al. Cisplatin-induced apoptosis in Hep3B cells: mitochondria-dependent and -independent pathways. Biochem Pharmacol. 2004;67:1459–1468. doi:10.1016/j.bcp.2003.12.013
  • Zhao W, You CC, Zhuang JP, et al. Viability inhibition effect of gambogic acid combined with cisplatin on osteosarcoma cells via mitochondria-independent apoptotic pathway. Mol Cell Biochem. 2013;382(1–2):243–252. doi:10.1007/s11010-013-1740-5
  • Li H, Fu L, Liu B, Lin X, Dong Q, Wang E. Ajuba overexpression regulates mitochondrial potential and glucose uptake through YAP/Bcl-xL/GLUT1 in human gastric cancer. Gene. 2019;693:16–24. doi:10.1016/j.gene.2019.01.018
  • Guo YJ, Pan WW, Liu SB, Shen ZF, Xu Y, Hu LL. ERK/MAPK signalling pathway and tumorigenesis. Exp Ther Med. 2020;19:1997–2007.
  • Dong Q, Fu L, Zhao Y, Tan S, Wang E. Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling. Oncotarget. 2017;8(10):17059–17069. doi:10.18632/oncotarget.15001
  • Ye Q, Cai W, Zheng Y, Evers BM, She QB. ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer. Oncogene. 2014;33:1828–1839. doi:10.1038/onc.2013.122

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