References
- KatsoROkkenhaugKAhmadiKWhiteSTimmsJWaterfieldMDCellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancerAnnu Rev Cell Dev Biol20011761567511687500
- WardSGFinanPIsoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agentsCurr Opin Pharmacol20033442643412901953
- SolitDBBassoADOlshenABScherHIRosenNInhibition of heat shock protein 90 function downregulates Akt kinase and sensitizes tumors to TaxolCancer Res20036392139214412727831
- ArboledaMJLyonsJFKabbinavarFFOverexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cellsCancer Res200363119620612517798
- GrilleSJBellacosaAUpsonJThe protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma linesCancer Res20036392172217812727836
- ComerFIHartGWO-Glycosylation of nuclear and cytosolic proteins. Dynamic interplay between O-GlcNAc and O-phosphateJ Biol Chem200027538291792918210924527
- HanoverJAKrauseMWLoveDCThe hexosamine signaling pathway: O-GlcNAc cycling in feast or famineBiochim Biophys Acta201018002809519647043
- HartGWHousleyMPSlawsonCCycling of O-linked β-Nacetylglucosamine on nucleocytoplasmic proteinsNature200744671391017102217460662
- WellsLVossellerKHartGWGlycosylation of nucleocytoplas-mic proteins: signal transduction and O-GlcNAcScience200129155122376237811269319
- HanoverJAGlycan-dependent signaling: O-linked N-acetylglucosamineFASEB J200115111865187611532966
- LazarusBDLoveDCHanoverJAO-GlcNAc cycling: implications for neurodegenerative disordersInt J Biochem Cell Biol200941112134214619782947
- YangWHParkSYNamHWNFκB activation is associated with its O-GlcNAcylation state under hyperglycemic conditionsProc Natl Acad Sci U S A200810545173451735018988733
- CaldwellSAJacksonSRShahriariKSNutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1Oncogene201029192831284220190804
- GuYMiWGeYGlcNAcylation Plays an Essential Role in Breast Cancer MetastasisCancer Res201070156344635120610629
- MiWGuYHanCO-GlcNAcylation is a novel regulator of lung and colon cancer malignancyBiochim Biophys Acta20111812451451921255644
- ChangFLeeJTNavolanicPMInvolvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapyLeukemia200317359060312646949
- LeeSHKimHSParkWSNon-small cell lung cancers frequently express phosphorylated Akt; an immunohistochemical studyAPMIS20021107–858759212390418
- JeongSJPise-MasisonCARadonovichMFParkHUBradyJNActivated AKT regulates NFκB activation, p53 inhibition and cell survival in HTLV-1-transformed cellsOncogene200524446719672816007163
- ZhangRXuYEkmanNEtk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factorinduced angiogenic pathwayJ Biol Chem200327851512675127614532277
- NamiecinskaMMarciniakKNowakJZVEGF as an angiogenic, neurotrophic, and neuroprotective factorPostepy Hig Med Dosw (Online)200559573583 Polish16407796
- TanPHXueSAManuntaMEffect of vectors on human endothelial cell signal transduction. implications for cardiovascular gene therapyArterioscler Thromb Vasc Biol200626346246716357316
- VigliettoGMottiMLBruniPCytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancerNat Med20028101136114412244303
- ZhouZHRaoJWuFSEMA3F prevented metastasis of col-orectal cancer by PI3K/Akt-dependent down-regulation of the ASCL2/CXCR4 AxisJ Pathol Epub2015410
- GuanNHuoXZhangZZhangSLuoJGuoWGinsenoside Rh2 inhibited metastasis of glioblastoma multiforme through Akt-regulated MMP13Tumour Biol Epub201543
- ZhangXShiHTangHFangZWangJCuiSmiR-218 inhibited the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathwayInt J Mol Med20153551301130825760926
- KangXKongFWuXHigh glucose promoted tumor invasion and increased metastasis-associated protein expression in human lung epithelial cells by upregulating heme oxygenase-1 via reactive oxygen species or the TGF-β1/PI3K/Akt signaling pathwayCell Physiol Biochem20153531008102225661467
- HuangXPanQSunDO-GlcNAcylation of cofilin promotes breast cancer cell invasionJ Biol Chem201328851364183642524214978
- AntonelliABocciGFallahiPCLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivoJ Clin Endocrinol Metab2014994E572E58124423321