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Original Research

Prognostic value of IGF-1R expression in bone and soft tissue sarcomas: a meta-analysis

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Pages 1949-1955 | Published online: 29 Jul 2015

References

  • BiermannJSAdkinsDRBenjaminRSBone cancerJ Natl Compr Canc Netw201086688712
  • SunLLiYZhangJLiHLiBYeZPrognostic value of pathologic fracture in patients with high grade localized osteosarcoma: a systemic review and meta-analysis of cohort studiesJ Orthop Res201533113113925231396
  • McKinseyELParrishJKIrwinAEA novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAsOncogene201130494910492021643012
  • BorinsteinSCBarkauskasDAKrailoMInvestigation of the insulin-like growth factor-1 signaling pathway in localized Ewing sarcoma: a report from the Children’s Oncology GroupCancer2011117214966497621480204
  • PappoASVassalGCrowleyJJA phase 2 trial of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF-1R), in patients with recurrent or refractory rhabdomyosarcoma, osteosarcoma, synovial sarcoma, and other soft tissue sarcomas: results of a Sarcoma Alliance for Research Through Collaboration studyCancer20141201624482456
  • ChughRGriffithKADavisEJDoxorubicin plus the IGF-1R antibody cixutumumab in soft tissue sarcoma: a phase I study using the TITE-CRM modelAnn Oncol201526714591464
  • ScotlandiKPicciPTargeting insulin-like growth factor 1 receptor in sarcomasCurr Opin Oncol2008204419427
  • RikhofBde JongSSuurmeijerAJMeijerCvan der GraafWTThe insulin-like growth factor system and sarcomasJ Pathol2009217446948219148905
  • AsmaneIWatkinEAlbertiLInsulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomasEur J Cancer201248163027303522682017
  • XieYSkyttingBNilssonGBrodinBLarssonOExpression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotypeCancer Res199959153588359110446966
  • WangYHHanXDQiuYIncreased expression of insulin-like growth factor-1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcomaJ Surg Oncol2012105323524321866554
  • van de LuijtgaardenACRoeffenMHLeusMAIGF signaling pathway analysis of osteosarcomas reveals the prognostic value of pAKT localizationFuture Oncol20139111733174024156333
  • WangYLipariPWangXA fully human insulin-like growth factor-I receptor antibody SCH 717454 (Robatumumab) has antitumor activity as a single agent and in combination with cytotoxics in pediatric tumor xenograftsMol Cancer Ther20109241041820124453
  • DuanZChoyEHarmonDInsulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell linesMol Cancer Ther2009882122213019638450
  • ScotlandiKManaraMCSerraMExpression of insulin-like growth factor system components in Ewing’s sarcoma and their association with survivalEur J Cancer20114781258126621345666
  • van de LuijtgaardenACVersleijen-JonkersYMRoeffenMHSchreuderHWFluckeUEvan der GraafWTPrognostic and therapeutic relevance of the IGF pathway in Ewing’s sarcoma patientsTarget Oncol20138425326023292309
  • PalmeriniEBenassiMSQuattriniIPrognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response?Orphanet J Rare Dis201510625613038
  • ChengHDodgeJMehlEValidation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarraysHum Pathol20094091244125119368956
  • van GaalJCRoeffenMHFluckeUESimultaneous targeting of insulin-like growth factor-1 receptor and anaplastic lymphoma kinase in embryonal and alveolar rhabdomyosarcoma: a rational choiceEur J Cancer201349163462347023867124
  • AhlénJWejdeJBrosjöOInsulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcomaClin Cancer Res200511120621615671548
  • TierneyJFStewartLAGhersiDBurdettSSydesMRPractical methods for incorporating summary time-to-event data into meta-analysisTrials200781617555582
  • KimWYJinQOhSHElevated epithelial insulin-like growth factor expression is a risk factor for lung cancer developmentCancer Res200969187439744819738076
  • Sheen-ChenSMChouFFHsuWHuangCCEngHLTangRPLack of prognostic value of insulin-like growth factor-1 in patients with breast cancer: analysis with tissue microarrayAnticancer Res2007275B3541354417972515
  • KodaMReszecJSulkowskaMKanczuga-KodaLSulkowskiSExpression of the insulin-like growth factor-I receptor and proapoptotic Bax and Bak proteins in human colorectal cancerAnn N Y Acad Sci2004103037738315659820
  • HeideggerIKernJOferPKlockerHMassonerPOncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesisOncotarget2014592723273524809298
  • ManiscalcoLIussichSMorelloEIncreased expression of insulin-like growth factor-1 receptor is correlated with worse survival in canine appendicular osteosarcomaVet J Epub 2014 Sep 10
  • MacEwenEGPastorJKutzkeJIGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcomaJ Cell Biochem2004921779115095405
  • KalekoMRutterWJMillerADOverexpression of the human insu-linlike growth factor I receptor promotes ligand-dependent neoplastic transformationMol Cell Biol19901024644732153917
  • FahrenholtzCDGreeneAMBeltranPJBurnsteinKLA novel calcium-dependent mechanism of acquired resistance to IGF-1 receptor inhibition in prostate cancer cellsOncotarget20145199007902125344862
  • KangZYuYZhuYJDownregulation of IGFBP2 is associated with resistance to IGF1R therapy in rhabdomyosarcomaOncogene201433505697570524292683
  • WagnerLMFouladiMAhmedAPhase II study of cixutumumab in combination with temsirolimus in pediatric patients and young adults with recurrent or refractory sarcoma: a report from the Children’s Oncology GroupPediatr Blood Cancer201562344044425446280
  • SchwartzGKTapWDQinLXCixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trialLancet Oncol201314437138223477833
  • CaoYRothMPiperdiSInsulin-like growth factor 1 receptor and response to anti-IGF1R antibody therapy in osteosarcomaPLoS One201498e10624925170759
  • MoraJRodríguezEde TorresCActivated growth signaling pathway expression in Ewing sarcoma and clinical outcomePediatr Blood Cancer201258453253821994054