References
- MedinaMAMarquezJde CastroINInterchange of amino acids between tumor and hostBiochem Med Metab Biol1992481171524866
- GieseCLepthienSMetznerLBrandschMBudisaNLilieHIntracellular uptake and inhibitory activity of aromatic fluorinated amino acids in human breast cancer cellsChem Med Chem2008391449145618752223
- ShikanoNOguraMOkudairaHUptake of 3-[125I]iodo-alpha-methyl-L-tyrosine into colon cancer DLD-1 cells: characterization and inhibitory effect of natural amino acids and amino acid-like drugsNucl Med Biol201037219720420152719
- CascinoAMuscaritoliMCangianoCPlasma amino acid imbalance in patients with lung and breast cancerAnticancer Res19951525075107763031
- NishihiraTTakagiTKawarabayashiYAnti-cancer therapy with valine-depleted amino acid imbalance solutionTohoku J Exp Med198815632592703150873
- LambRFAmino acid sensing mechanisms: an Achilles heel in cancer?FEBS J2012279152624263122686629
- GoberdhanDCIntracellular amino acid sensing and mTORC1-regulated growth: new ways to block an old target?Curr Opin Investig Drugs2010111213601367
- HurdleJGO’NeillAJChopraIProspects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agentsAntimicrob Agents Chemother200549124821483316304142
- LeeSWKangYSKimSMultifunctional proteins in tumorigenesis: aminoacyl-tRNA synthetases and translational componentsCurr Proteom200634233247
- ParkSGSchimmelPKimSAminoacyl tRNA synthetases and their connections to diseaseProc Natl Acad Sci U S A200810532110431104918682559
- GallinettiJHarputlugilEMitchellJRAmino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TORBiochem J2013449111023216249
- ShinSHKimHSJungSHXuHDJeongYBChungYJImplication of leucyl-tRNA synthetase 1 (LARS1) over-expression in growth and migration of lung cancer cells detected by siRNA targeted knock-down analysisExp Mol Med200840222923618446061
- GaoJAksoyBADogrusozUIntegrative analysis of complex cancer genomics and clinical profiles using the cBioPortalSci Signal20136269pl123550210
- CeramiEGaoJDogrusozUThe cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics dataCancer Discov2012240140410.1158/2159-8290.CD-12-009522588877
- ParkHDavidsonEKingMPOverexpressed mitochondrial leucyl-tRNA synthetase suppresses the A3243G mutation in the mitochondrial tRNA(Leu(UUR)) geneRNA200814112407241618796578
- MayrJAMeierhoferDZimmermannFLoss of complex I due to mitochondrial DNA mutations in renal oncocytomaClin Cancer Res20081482270227518413815
- BakerSJZhangYKAkamaTDiscovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690), for the potential treatment of onychomycosisJ Med Chem2006494447445016854048
- ZhaoYWangQMengQIdentification of Trypanosoma brucei leucyl-tRNA synthetase inhibitors by pharmacophore- and docking-based virtual screening and synthesisBioorg Med Chem20122031240125022249121
- GaoGYaoYDingDYeLZhouHLiDThe establishement of an anti-Trypanosoma drug screening system with leucyl-tRNA synthetase as an inhibition targetChina Biotechnol200929121317
- MosmannTRapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assaysJ Immunol Methods1983651–255636606682
- TaoJSchimmelPInhibitors of aminoacyl-tRNA synthetases as novel anti-infectivesExpert Opin Investig Drugs20009817671775
- SchwartzGJCentral leucine sensing in the control of energy homeostasisEndocrinol Metab Clin North Am2013421818723391241
- KawamuraTLiuDTowleMJAnti-angiogenesis effects of borrelidin are mediated through distinct pathways: threonyl-tRNA synthetase and caspases are independently involved in suppression of proliferation and induction of apoptosis in endothelial cellsJ Antibiot (Tokyo)200356870971514563161
- AntonellisAGreenEDThe role of aminoacyl-tRNA synthetases in genetic diseasesAnnu Rev Genomics Hum Genet200898710718767960
- RockFLMaoWYaremchukAAn antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing siteScience200731658321759176117588934
- KimSYouSHwangDAminoacyl-tRNA synthetases and tumorigenesis: more than housekeepingNat Rev Cancer2011111070871821941282
- HanJMParkBJParkSGAIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stress via p53Proc Natl Acad Sci U S A200810532112061121118695251
- ParkBJKangJWLeeSWThe haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATRCell2005120220922115680327
- WaldmanTKinzlerKWVogelsteinBp21 is necessary for the p53-mediated G1 arrest in human cancer cellsCancer Res19955522518751907585571
- RoninsonIBOncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblastsCancer Lett2002179111411880176