Polo-like kinase 2 acting as a promoter in human tumor cells with an abundance of TAp73

References

• DuWJiangPMancusoATAp73 enhances the pentose phosphate pathway and supports cell proliferationNat Cell Biol2013158991100023811687
   PubMed Web of Science ®Google Scholar
• LlamazaresSMoreiraATavaresAPolo encodes a protein kinase homolog required for mitosis in DrosophilaGenes Dev1991512A215321651660828
   PubMed Web of Science ®Google Scholar
• ZitouniSNabaisCJanaSCGuerreroABettencourt-DiasMPolo-like kinases: structural variations lead to multiple functionsNat Rev Mol Cell Biol201415743345224954208
   PubMed Web of Science ®Google Scholar
• RaabMKrämerAHehlgansSMitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1Mol Oncol20159114015425169932
   PubMed Web of Science ®Google Scholar
• SanhajiMRitterABelshamHRPolo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosisOncotarget20145103130314424931513
   PubMedGoogle Scholar
• BowersSTruongAPYeMDesign and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitorsBioorg Med Chem Lett20132392743274923522834
   PubMed Web of Science ®Google Scholar
• LiJMaWWangPYHurleyPJBunzFHwangPMPolo-like kinase 2 activates an antioxidant pathway to promote the survival of cells with mitochondrial dysfunctionFree Radic Biol Med20147327027724887096
   PubMed Web of Science ®Google Scholar
• SeetBTDikicIZhouMMPawsonTReading protein modifications with interaction domainsNat Rev Mol Cell Biol20067747348316829979
   PubMed Web of Science ®Google Scholar
• UbersaxJAFerrellJEMechanisms of specificity in protein phosphorylationNat Rev Mol Cell Biol20078753054117585314
   PubMed Web of Science ®Google Scholar
• ManningGWhyteDBMartinezRHunterTSudarsanamSThe protein kinase complement of the human genomeScience200229856001912193412471243
   PubMed Web of Science ®Google Scholar
• LuHYanCQuanXXCK2 phosphorylates and inhibits TAp73 tumor suppressor function to promote expression of cancer stem cell genes and phenotype in head and neck cancerNeoplasia2014161078980025379016
   PubMed Web of Science ®Google Scholar
• SongyangZLuKPKwonYTA structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1Mol Cell Biol19961611648664938887677
   PubMed Web of Science ®Google Scholar
• MbefoMKPaleologouKEBoucharabaAPhosphorylation of synucleins by members of the Polo-like kinase familyJ Biol Chem201028542807282219889641
   PubMed Web of Science ®Google Scholar
• SchreursSGerardMDeruaRIn vitro phosphorylation does not influence the aggregation kinetics of WT α-synuclein in contrast to its phosphorylation mutantsInt J Mol Sci20141511040106724434619
   PubMed Web of Science ®Google Scholar
• ObenauerJCCantleyLCYaffeMBScansite 2.0: proteome-wide prediction of cell signaling interactions using short sequence motifsNucleic Acids Res200331133635364112824383
   PubMed Web of Science ®Google Scholar
• LiuZRenJCaoJSystematic analysis of the Plk-mediated phosphoregulation in eukaryotesBrief Bioinform201314334436022851512
   PubMed Web of Science ®Google Scholar
• HornbeckPVZhangBMurrayBKornhauserJMLathamVSkrzypekEPhosphoSitePlus, 2014: mutations, PTMs and recalibrationsNucleic Acids Res201543Database issueD512D52025514926
   PubMed Web of Science ®Google Scholar
• LuHYangXDuggalPTNF-alpha promotes c-REL/DeltaNp63alpha interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancerCancer Res201171216867687721933882
   PubMed Web of Science ®Google Scholar
• ThakurASunYBolligAAnti-invasive and antimetastatic activities of ribosomal protein S6 kinase 4 in breast cancer cellsClin Cancer Res200814144427443618628456
   PubMed Web of Science ®Google Scholar
• FitzgeraldKBergeronMWillitsCPharmacological inhibition of Polo like kinase 2 (PLK2) does not cause chromosomal damage or result in the formation of micronucleiToxicol Appl Pharmacol201326911723466428
   PubMed Web of Science ®Google Scholar
• AubeleDLHomRKAdlerMSelective and brain-permeable Polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brainChemMedChem2013881295131323794260
   PubMed Web of Science ®Google Scholar
• KinoshitaEKinoshita-KikutaETakiyamaKKoikeTPhosphate-binding tag, a new tool to visualize phosphorylated proteinsMol Cell Proteomics20065474975716340016
   PubMed Web of Science ®Google Scholar
• GotoHKosakoHTanabeKPhosphorylation of vimentin by rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesisJ Biol Chem19982731911728117369565595
   PubMed Web of Science ®Google Scholar
• MaSLiuMAYuanYLEriksonRLThe serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIBMol Cancer Res20031537638412651910
   PubMed Web of Science ®Google Scholar
• FuLLiuNHanYXieCLiQWangEADAM10 regulates proliferation, invasion, and chemoresistance of bladder cancer cellsTumour Biol20143599263926824935471
   PubMedGoogle Scholar
• FloresERTsaiKYCrowleyDp63 and p73 are required for p53-dependent apoptosis in response to DNA damageNature2002416688056056411932750
   PubMed Web of Science ®Google Scholar
• Shimizu-YoshidaYSugiyamaKRogounovitchTRadiation-inducible hSNK gene is transcriptionally regulated by p53 binding homology element in human thyroid cellsBiochem Biophys Res Commun2001289249149811716500
   PubMed Web of Science ®Google Scholar
• OkadaKKanayaSAsaiKAccurate extraction of functional associations between proteins based on common interaction partners and common domainsBioinformatics20052192043204815699027
   PubMed Web of Science ®Google Scholar
• LogothetiSPavlopoulouAGaltsidisSVojtesekBZoumpourlisVFunctions, divergence and clinical value of TAp73 isoforms in cancerCancer Metastasis Rev2013323–451153423592418
   PubMed Web of Science ®Google Scholar
• BurgeSTeufelDPTownsleyFMFreundSMBycroftMFershtARMolecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylationProc Natl Acad Sci U S A200910693142314719218448
   PubMed Web of Science ®Google Scholar
• KoidaNOzakiTYamamotoHInhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylationJ Biol Chem2008283138555856318174154
   PubMed Web of Science ®Google Scholar
• PaliwalPRadhaVSwarupGRegulation of p73 by Hck through kinase-dependent and independent mechanismsBMC Mol Biol200784517535448
   PubMed Web of Science ®Google Scholar
• GonzalezSPrivesCCordon-CardoCp73alpha regulation by Chk1 in response to DNA damageMol Cell Biol200323228161817114585975
   PubMed Web of Science ®Google Scholar
• BenosmanSMengXVon GrabowieckiYComplex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neuronsJ Biol Chem201128650430134302522002055
   PubMed Web of Science ®Google Scholar
• MerloPFulcoMCostanzoAA role of p73 in mitotic exitJ Biol Chem200528034303543036015985436
   PubMed Web of Science ®Google Scholar
• GaiddonCLokshinMGrossICyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73J Biol Chem200327830274212743112676926
   PubMed Web of Science ®Google Scholar
• NiikuraYOgiHKikuchiKKitagawaKBUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD)Cell Death Differ20101761011102420057499
   PubMed Web of Science ®Google Scholar
• YuanZMShioyaHIshikoTp73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damageNature1999399673881481710391251
   PubMed Web of Science ®Google Scholar
• AgamiRBlandinoGOrenMShaulYInteraction of c-Abl and p73alpha and their collaboration to induce apoptosisNature1999399673880981310391250
   PubMed Web of Science ®Google Scholar
• BunjobpolWDullooIIgarashiKConcinNMatsuoKSabapathyKSuppression of acetylpolyamine oxidase by selected AP-1 members regulates DNp73 abundance: mechanistic insights for overcoming DNp73-mediated resistance to chemotherapeutic drugsCell Death Differ20142181240124924722210
   PubMed Web of Science ®Google Scholar
• YangAWalkerNBronsonRp73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumoursNature200040467739910310716451
   PubMed Web of Science ®Google Scholar
• PozniakCDRadinovicSYangAMcKeonFKaplanDRMillerFDAn anti-apoptotic role for the p53 family member, p73, during developmental neuron deathScience2000289547730430610894779
   PubMed Web of Science ®Google Scholar
• Niklison-ChirouMVSteinertJRAgostiniMTAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptorProc Natl Acad Sci U S A201311047189521895724190996
   PubMed Web of Science ®Google Scholar
• LevineAJTomasiniRMcKeonFDMakTWMelinoGThe p53 family: guardians of maternal reproductionNat Rev Mol Cell Biol201112425926521427767
   PubMed Web of Science ®Google Scholar
• MollUMSladeNp63 and p73: roles in development and tumor formationMol Cancer Res20042737138615280445
   PubMed Web of Science ®Google Scholar
• SyedNColeyHMSehouliJPolo-like kinase Plk2 is an epigenetic determinant of chemosensitivity and clinical outcomes in ovarian cancerCancer Res20117193317332721402713
   PubMed Web of Science ®Google Scholar
• TanLBChenKTYuanYCLiaoPCGuoHRIdentification of urine PLK2 as a marker of bladder tumors by proteomic analysisWorld J Urol201028111712219506885
   PubMed Web of Science ®Google Scholar
• SyedNSmithPSullivanATranscriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignanciesBlood2006107125025616160013
   PubMed Web of Science ®Google Scholar
• EckerdtFYuanJStrebhardtKPolo-like kinases and oncogenesisOncogene200524226727615640842
   PubMed Web of Science ®Google Scholar
• MatsumotoTWangPYMaWSungHJMatobaSHwangPMPolo-like kinases mediate cell survival in mitochondrial dysfunctionProc Natl Acad Sci U S A200910634145421454619706541
   PubMed Web of Science ®Google Scholar
• MatthewEMYenTJDickerDTReplication stress, defective S-phase checkpoint and increased death in Plk2-deficient human cancer cellsCell Cycle20076202571257817912033
   PubMed Web of Science ®Google Scholar
• LiuXEriksonRLPolo-like kinase (Plk)1 depletion induces apoptosis in cancer cellsProc Natl Acad Sci U S A2003100105789579412732729
   PubMed Web of Science ®Google Scholar
• ShenTLiYYangLUpregulation of Polo-like kinase 2 gene expression by GATA-1 acetylation in human osteosarcoma MG-63 cellsInt J Biochem Cell Biol201244242342922138223
   PubMed Web of Science ®Google Scholar
• ZhaoWZhangBGuoXExpression of Ki-67, Bax and p73 in patients with hilar cholangiocarcinomaCancer Biomark201414419720224934361
   PubMed Web of Science ®Google Scholar
• MollUMThe role of p63 and p73 in tumor formation and progression: coming of age toward clinical usefulness. Commentary re: Koga F et al, Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. Clin. Cancer Res. 9: 5501–5507, 2003, and Puig P et al, p73 Expression in human normal and tumor tissues: loss of p73alpha expression is associated with tumor progression in bladder Cancer. Clin. Cancer Res. 9: 5642–5651, 2003Clin Cancer Res20039155437544114654522
   PubMed Web of Science ®Google Scholar
• PhosphoSitePlus: a protein modification resource [webpage on the Internet]Cell Signaling Technology, Inc2013 Available from: www.PhosphoSitePlus.orgAccessed November 10, 2015
   Google Scholar