DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion

References

• KehletHJensenTSWoolfCJPersistent postsurgical pain: risk factors and preventionLancet200636795221618162516698416
   PubMed Web of Science ®Google Scholar
• GanTJHabibASMillerTEWhiteWApfelbaumJLIncidence, patient satisfaction, and perceptions of post-surgical pain: results from a US national surveyCurr Med Res Opin201430114916024237004
   PubMed Web of Science ®Google Scholar
• PolkkiTPietilaAMVehvilainen-JulkunenKHospitalized children’s descriptions of their experiences with postsurgical pain relieving methodsInt J Nurs Stud2003401334412550148
   PubMed Web of Science ®Google Scholar
• MacraeWAChronic post-surgical pain: 10 years onBr J Anaesth20081011778618434337
   PubMed Web of Science ®Google Scholar
• LandmanZOswaldTSandersJDiabMSpinal Deformity Study GroupPrevalence and predictors of pain in surgical treatment of adolescent idiopathic scoliosisSpine (Phila Pa 1976)2011361082582921192302
   PubMed Web of Science ®Google Scholar
• PageMGStinsonJCampbellFIsaacLKatzJIdentification of pain-related psychological risk factors for the development and maintenance of pediatric chronic postsurgical painJ Pain Res2013616718023503375
   PubMed Web of Science ®Google Scholar
• KainZNMayesLCO’ConnorTZCicchettiDVPreoperative anxiety in children. Predictors and outcomesArch Pediatr Adolesc Med199615012123812458953995
   PubMedGoogle Scholar
• LaCroix-FralishMLAustinJSZhengFYLevitinDJMogilJSPatterns of pain: meta-analysis of microarray studies of painPain201115281888189821561713
   PubMed Web of Science ®Google Scholar
• De GregoriMDiatchenkoLIngelmoPMHuman genetic variability contributes to postoperative morphine consumptionJ Pain201617562863626902643
   PubMed Web of Science ®Google Scholar
• SadhasivamSChidambaranVPharmacogenomics of opioids and perioperative pain managementPharmacogenomics201213151719174023171337
   PubMed Web of Science ®Google Scholar
• SadhasivamSChidambaranVOlbrechtVAGenetics of pain perception, COMT and postoperative pain management in childrenPharmacogenomics201415327728424533707
   PubMed Web of Science ®Google Scholar
• ClarkeHKatzJFlorHRietschelMDiehlSRSeltzerZGenetics of chronic post-surgical pain: a crucial step toward personal pain medicineCan J Anaesth201562329430325471684
   PubMed Web of Science ®Google Scholar
• UhlGRSoraIWangZThe mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responsesProc Natl Acad Sci U S A199996147752775510393893
   PubMed Web of Science ®Google Scholar
• BranfordRDroneyJRossJROpioid genetics: the key to personalized pain control?Clin Genet201282430131022780883
   PubMed Web of Science ®Google Scholar
• LeeMGKimHJLeeKHChoiYSThe influence of genotype polymorphism on morphine analgesic effect for postoperative pain in childrenKorean J Pain2016291343926839669
   PubMed Web of Science ®Google Scholar
• WalterCLotschJMeta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatmentPain2009146327027519683391
   PubMed Web of Science ®Google Scholar
• BeyerAKochTSchroderHSchulzSHolltVEffect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptorJ Neurochem200489355356015086512
   PubMed Web of Science ®Google Scholar
• MogilJSPain genetics: past, present and futureTrends Genet201228625826622464640
   PubMed Web of Science ®Google Scholar
• BirdAPerceptions of epigeneticsNature2007447714339639817522671
   PubMed Web of Science ®Google Scholar
• BuchheitTVan de VenTShawAEpigenetics and the transition from acute to chronic painPain Med201213111474149022978429
   PubMed Web of Science ®Google Scholar
• CrowMDenkFMcMahonSBGenes and epigenetic processes as prospective pain targetsGenome Med2013521223409739
   PubMed Web of Science ®Google Scholar
• UshijimaTNakajimaTMaekitaTDNA methylation as a marker for the past and futureJ Gastroenterol200641540140716799880
   PubMed Web of Science ®Google Scholar
• HwangCKSongKYKimCSEvidence of endogenous mu opioid receptor regulation by epigenetic control of the promotersMol Cell Biol200727134720473617452465
   PubMed Web of Science ®Google Scholar
• OertelBGDoehringARoskamBGenetic-epigenetic interaction modulates μ-opioid receptor regulationHum Mol Genet201221214751476022875838
   PubMed Web of Science ®Google Scholar
• ChorbovVMTodorovAALynskeyMTCiceroTJElevated levels of DNA methylation at the OPRM1 promoter in blood and sperm from male opioid addictsJ Opioid Manag20117425826421957825
   PubMedGoogle Scholar
• NielsenDAYuferovVHamonSIncreased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addictsNeuropsychopharmacology200934486787318650805
   PubMed Web of Science ®Google Scholar
• von BaeyerCLNumerical rating scale for self-report of pain intensity in children and adolescents: recent progress and further questionsEur J Pain200913101005100719766028
   PubMed Web of Science ®Google Scholar
• BringuierSDadureCRauxODuboisAPicotMCCapdevilaXThe perioperative validity of the visual analog anxiety scale in children: a discriminant and useful instrument in routine clinical practice to optimize postoperative pain managementAnesth Analg2009109373774419690240
   PubMed Web of Science ®Google Scholar
• MacraeWADaviesHTOChronic Postsurgical PainSeattleIASP Press1999
   Google Scholar
• GerbershagenHJRothaugJKalkmanCJMeissnerWDetermination of moderate-to-severe postoperative pain on the numeric rating scale: a cut-off point analysis applying four different methodsBr J Anaesth2011107461962621724620
   PubMed Web of Science ®Google Scholar
• ChidambaranVMooreDSpruanceKPredicting the pain continuum after adolescent idiopathic scoliosis surgery – a prospective cohort studyEur J Pain2017
   Web of Science ®Google Scholar
• BursacZGaussCHWilliamsDKHosmerDWPurposeful selection of variables in logistic regressionSource Code Biol Med200831719087314
   PubMedGoogle Scholar
• ENCODE Project ConsortiumAn integrated encyclopedia of DNA elements in the human genomeNature20124897414577422955616
   PubMed Web of Science ®Google Scholar
• BernsteinBEStamatoyannopoulosJACostelloJFThe NIH Roadmap Epigenomics Mapping ConsortiumNat Biotechnol201028101045104820944595
   PubMed Web of Science ®Google Scholar
• LiuTOrtizJATaingLCistrome: an integrative platform for transcriptional regulation studiesGenome Biol2011128R8321859476
   PubMed Web of Science ®Google Scholar
• GriffonABarbierQDalinoJvan HeldenJSpicugliaSBallesterBIntegrative analysis of public ChIP-seq experiments reveals a complex multi-cell regulatory landscapeNucleic Acids Res2015434e2725477382
   PubMed Web of Science ®Google Scholar
• ErnstJKheradpourPMikkelsenTSMapping and analysis of chromatin state dynamics in nine human cell typesNature20114737345434921441907
   PubMed Web of Science ®Google Scholar
• KochCMAndrewsRMFlicekPThe landscape of histone modifications across 1% of the human genome in five human cell linesGenome Res200717669170717567990
   PubMed Web of Science ®Google Scholar
• BarskiACuddapahSCuiKHigh-resolution profiling of histone methylations in the human genomeCell2007129482383717512414
   PubMed Web of Science ®Google Scholar
• CreyghtonMPChengAWWelsteadGGHistone H3K27ac separates active from poised enhancers and predicts developmental stateProc Natl Acad Sci U S A201010750219312193621106759
   PubMed Web of Science ®Google Scholar
• DenkFMcMahonSBTraceyIPain vulnerability: a neurobiological perspectiveNat Neurosci201417219220024473267
   PubMed Web of Science ®Google Scholar
• WachmanEMHayesMJLesterBMEpigenetic variation in the mu-opioid receptor gene in infants with neonatal abstinence syndromeJ Pediatr2014165347247824996986
   PubMed Web of Science ®Google Scholar
• HwangCKSongKYKimCSEpigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factorJ Cell Mol Med2009139B3591361519602036
   PubMed Web of Science ®Google Scholar
• KnotheCOertelBGUltschAPharmacoepigenetics of the role of DNA methylation in μ-opioid receptor expression in different human brain regionsEpigenomics20168121583159927685027
   PubMed Web of Science ®Google Scholar
• PorrecaFTangQBBianDRiedlMEldeRLaiJSpinal opioid mu receptor expression in lumbar spinal cord of rats following nerve injuryBrain Res19987951–21972039622629
   PubMed Web of Science ®Google Scholar
• VietCTDangDYeYOnoKCampbellRRSchmidtBLDemethylating drugs as novel analgesics for cancer painClin Cancer Res201420184882489324963050
   PubMed Web of Science ®Google Scholar
• ZhouXLYuLNWangYIncreased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic painMol Pain2014105125118039
   PubMed Web of Science ®Google Scholar
• SunYSahbaiePLiangDDNA methylation modulates nociceptive sensitization after incisionPLoS One20151011e014204626535894
   PubMed Web of Science ®Google Scholar
• DoehringAOertelBGSittlRLotschJChronic opioid use is associated with increased DNA methylation correlating with increased clinical painPain20131541152323273101
   PubMed Web of Science ®Google Scholar
• DenkFMcMahonSBChronic pain: emerging evidence for the involvement of epigeneticsNeuron201273343544422325197
   PubMed Web of Science ®Google Scholar
• FormisanoLNohKMMiyawakiTMashikoTBennettMVZukinRSIschemic insults promote epigenetic reprogramming of mu opioid receptor expression in hippocampal neuronsProc Natl Acad Sci U S A2007104104170417517360495
   PubMed Web of Science ®Google Scholar
• BruceAWDonaldsonIJWoodICGenome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genesProc Natl Acad Sci U S A200410128104581046315240883
   PubMed Web of Science ®Google Scholar
• SchoenherrCJAndersonDJThe neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genesScience19952675202136013637871435
   PubMed Web of Science ®Google Scholar
• BuckleyNJJohnsonRZuccatoCBithellACattaneoEThe role of REST in transcriptional and epigenetic dysregulation in Huntington’s diseaseNeurobiol Dis2010391283920170730
   PubMed Web of Science ®Google Scholar
• UchidaHMaLUedaHEpigenetic gene silencing underlies C-fiber dysfunctions in neuropathic painJ Neurosci201030134806481420357131
   PubMed Web of Science ®Google Scholar
• BanksCJJoshiAMichoelTFunctional transcription factor target discovery via compendia of binding and expression profilesSci Rep201662064926857150
   PubMed Web of Science ®Google Scholar
• FanSZhangXCpG island methylation pattern in different human tissues and its correlation with gene expressionBiochem Biophys Res Commun2009383442142519364493
   PubMed Web of Science ®Google Scholar
• DaviesMNVoltaMPidsleyRFunctional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and bloodGenome Biol2012136R4322703893
   PubMed Web of Science ®Google Scholar
• AndreaeMHAndreaeDARegional anaesthesia to prevent chronic pain after surgery: a Cochrane systematic review and meta-analysisBr J Anaesth2013111571172023811426
   PubMed Web of Science ®Google Scholar
• KiefferBLEvansCJOpioid tolerance-in search of the holy grailCell2002108558759011893329
   PubMed Web of Science ®Google Scholar
• LawPYLohHHWeiLNInsights into the receptor transcription and signaling: implications in opioid tolerance and dependenceNeuropharmacology200447Suppl 130031115464146
   PubMed Web of Science ®Google Scholar