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Review

A spoonful of sugar helps the medicine go down? A review of strategies for making pills easier to swallow

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Pages 1337-1346 | Published online: 26 Jul 2018

References

  • LiuFGhaffurABainsJHamdySAcceptability of oral solid medicines in older adults with and without dysphagia: a nested pilot validation questionnaire based observational studyInt J Pharm2016512237438126970368
  • LauETLSteadmanKJMakMCicheroJAYNissenLMPrevalence of swallowing difficulties and medication modification in customers of community pharmacistsJ Pharm Pract Res20154511823
  • KellyJWrightDAdministering medication to adult patients with dysphagiaNurs Stand200923296268
  • TahainehLWazaifyMDifficulties in swallowing oral medications in JordanInt J Clin Pharm201739237337928281225
  • PR Newswire40% of American adults report experiencing difficulty swallowing pills – national survey shows many failed to take medication as directed – because of difficulty swallowing pillsNew YorkPR Newswire Association LLC2004 https://jacksonbondenterprises.wordpress.com/2013/09/18/40-of-american-adults-report-experiencing-difficulty-swallowing-pills/Accessed July 11, 2017
  • SchieleJTQuinzlerRKlimmHDPruszydloMGHaefeliWEDifficulties swallowing solid oral dosage forms in a general practice population: prevalence, causes, and relationship to dosage formsEur J Clin Pharmacol201369493794823052416
  • DugganJMShuklaVAkpanudoBGuttersonGEitniearLSahloffEDoc, I just can’t swallow pills: HIV infected patients and pill phago-phobiaJ AIDS Clin Res201459348
  • MarquisJSchneiderMPPayotVSwallowing difficulties with oral drugs among polypharmacy patients attending community pharmaciesInt J Clin Pharm20133561130113623963541
  • StrachanIGreenerMMedication-related swallowing difficulties may be more common than we realisePharm Pract20051510411414
  • WrightDMedication administration in nursing homesNurs Stand200216423338
  • FuscoSCariatiDSchepisiRManagement of oral drug therapy in elderly patients with dysphagiaJ Gerontol Geriatr2016641920
  • ForoughASWongSYMLauETLNurse experiences of medication administration to people with swallowing difficulties living in aged care facilities: a systematic review of qualitative evidenceJBI Database System Rev Implement Rep20181617186
  • NissenLMHaywoodASteadmanKJSolid medication dosage form modification at the bedside and in the pharmacy of Queensland hospitalsJ Pharm Pract Res2009392129134
  • MercovichNKyleGJNauntonMSafe to crush? A pilot study into solid dosage form modification in aged careAustralas J Ageing201433318018424521076
  • SchierJGHowlandMAHoffmanRSNelsonLSFatality from administration of labetalol and crushed extended-release nifedipineAnn Pharmacother200337101420142314519033
  • TerréRMearinFEffectiveness of chin-down posture to prevent tracheal aspiration in dysphagia secondary to acquired brain injury. A video-fluoroscopy studyNeurogastroenterol Motil201224541441922309385
  • SchieleJTSchneiderHQuinzlerRReichGHaefeliWETwo techniques to make swallowing pills easierAnn Fam Med201412655055225384817
  • KaplanBJSteigerRAPopeJMarshASharpMCrawfordSGSuccessful treatment of pill-swallowing difficulties with head posture practicePaediatr Child Health2010155e1e521532781
  • LogemannJAGenslerGRobbinsJA randomized study of three interventions for aspiration of thin liquids in patients with dementia or Parkinson’s diseaseJ Speech Lang Hear Res200851117318318230864
  • BülowMOlssonREkbergOVideomanometric analysis of supraglottic swallow, effortful swallow, and chin tuck in patients with pharyngeal dysfunctionDysphagia200116319019511453566
  • YetzerEBlakeKGoetschNShookMPaulMStSAFE medication management for patients with physical impairments of stroke, part oneRehabil Nurs201540426026625447351
  • MediStraw [homepage on the Internet]Pill taking made E-Z 2006 [cited December 2, 2016]. Available from: http://www.medistraw.com/Accessed March 29, 2017
  • SchieleJTPennerHSchneiderHSwallowing tablets and capsules increases the risk of penetration and aspiration in patients with stroke-induced dysphagiaDysphagia201530557158226205435
  • Carnaby-MannGCraryMPill swallowing by adults with dysphagiaArch Otolaryngol Head Neck Surg20051311197097516301368
  • González-FernándezMDanielsSKDysphagia in stroke and neurologic diseasePhys Med Rehabil Clin N Am2008194867888x18940646
  • CrinoLManrique-TorresYJCicheroJASteadmanKJCharacterization of Gloup: is it suitable for medication delivery in dysphagic patients?APSA-ASCEPT Joint Scientific MeetingNovember 29–December 2, 2015Hobart, Tasmania
  • UlozaVUlozieneIGradauskieneEA randomized cross-over study to evaluate the swallow-enhancing and taste-masking properties of a novel coating for oral tabletsPharm World Sci201032442042320524068
  • DiamondSLavalleeDCExperience with a pill-swallowing enhancement aidClin Pediatr (Phila)201049439139320118076
  • CzyzewskiDICallesNRRunyanRDLopezMATeaching and maintaining pill swallowing in HIV-infected childrenAIDS Read20001028895
  • BeckMHCataldoMSliferKJPulbrookVGuhmanJKTeaching children with attention deficit hyperactivity disorder (ADHD) and autistic disorder (AD) how to swallow pillsClin Pediatr (Phila)200544651552616015399
  • GarviePALensingSRaiSNEfficacy of a pill-swallowing training intervention to improve antiretroviral medication adherence in pediatric patients with HIV/AIDSPediatrics20071194e893e89917353298
  • HansenDLTuliniusDHansenEHAdolescents’ struggles with swallowing tablets: barriers, strategies and learningPharm World Sci2008301656917594531
  • HawCStubbsJAdministration of medicines in food and drink: a study of older inpatients with severe mental illnessInt Psychogeriatr201022340941620078907
  • KaurTGillBKumarSGuptaGDMouth dissolving tablets: a novel approach to drug deliveryInt J Curr Pharm Res20113117
  • FalconerJRSteadmanKJExtemporaneously compounded medicinesAust Prescr2017401528246428
  • LugoRAKernSEThe pharmacokinetics of oxycodoneJ Pain Palliat Care Pharmacother20051841730
  • KellyJD’CruzGWrightDA qualitative study of the problems surrounding medicine administration to patients with dysphagiaDysphagia2009241495618688675
  • WrightDSwallowing difficulties protocol: medication administrationNurs Stand20021714–154345
  • McLachlanAJRamzanIMisuse of formulations in the aged care settingKochSGlothFMNayRMedication Management in Older Adults: A Concise Guide for CliniciansLondonSpringer201095104
  • BurridgeNDeidunDAustralian Don’t Rush to Crush Handbook: Therapeutic Options for People Unable to Swallow Solid Oral Medicines1st edCollingwood, VICSociety of Hospital Pharmacists of Australia2011
  • ParadisoLMRougheadEEGilbertALCrushing or altering medications: what’s happening in residential aged-care facilities?Australas J Ageing2002213123127
  • StubbsJHawCDickensGDose form modification — a common but potentially hazardous practice. A literature review and study of medication administration to older psychiatric inpatientsInt Psychogeriatr200820361662717711606
  • ThongMYManriqueYJSteadmanKJDrug loss while crushing tablets: comparison of 24 tablet crushing devicesPLoS One2018133e019368329494695
  • Mc GillicuddyACreanAMSahmLJOlder adults with difficulty swallowing oral medicines: a systematic review of the literatureEur J Clin Pharmacol201672214115126573594
  • ValanisBVollmerWMSteelePOccupational exposure to antineoplastic agents: self-reported miscarriages and stillbirths among nurses and pharmacistsJ Occup Environ Med199941863263810457505
  • SchmidtLEDalhoffKFood-drug interactionsDrugs200262101481150212093316
  • ManriqueYJLeeDJIslamFCrushed tablets: does the administration of food vehicles and thickened fluids to aid medication swallowing alter drug release?J Pharm Pharm Sci201417220721924934549
  • McCabe-SellersBFrankelEHWolfeJJHandbook of Food-Drug InteractionsBoca Raton, FLCRC Press2003
  • ShragerL webpage on the InternetIt can be a hard pill to swallow 2011 [cited January 15, 2018]. Available from: https://www.everyday-health.com/columns/lynda-shrager-the-organized-caregiver/it-can-be-a-hard-pill-to-swallow/Accessed January 20, 2018