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Original Research

Mediating Effect Of The Motivation For Medication Use On Disease Management And Medication Adherence Among Community-Dwelling Patients With Schizophrenia

, , ORCID Icon, , & ORCID Icon
Pages 1877-1887 | Published online: 05 Nov 2019

References

  • National Institute of Mental Health. Mental health information. 2018 Available from: https://www.nimh.nih.gov/health/statistics/schizophrenia.shtml Accessed 39, 2019.
  • Ministry of Health and Welfare. The numbers of individuals with disabilities. 2016 Available from: http://www.mohw.gov.tw/cht/DOS/Statistic.aspx?f_list_no=312&fod_list_no=4198 Accessed 410, 2017.
  • Leucht S, Corves C, Arbter D, Engel RR, Li C, Davis JM. Second-generation versus first- generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet. 2009;373(9657):31–41. doi:10.1016/S0140-6736(08)61764-X19058842
  • Miller BJ, Bodenheimer C, Crittenden K. Second-generation antipsychotic discontinuation in first episode psychosis: an updated review. Clin Psychopharmacol Neurosci. 2011;9(2):45–53. doi:10.9758/cpn.2011.9.2.4523429653
  • Sendt KV, Tracy DK, Bhattacharyya S. A systematic review of factors influencing adherence to antipsychotic medication in schizophrenia-spectrum disorders. Psychiatry Res. 2015;225(1):14–30. doi:10.1016/j.psychres.2014.11.00225466227
  • Rong JR, Yang TY, Laiu WI, Hung TM, Hung FF, Shiau SJ. Exploring essential competences and credentialing model of community psychiatric mental health nursing. J Psychiatr Ment Health Nurs. 2008;3(2):1–9.
  • Huang JY, Chen HM. Concept analysis of medication adherence in patients with chronic disease. J Nurs. 2014;61(3):112–118. doi:10.6224/JN.61.3.112.
  • World Health Organization. Adherence to long-term therapies: policy for action. 2001 Available from: http://www.who.int/chp/knowledge/publications/adherencerep.pdf Accessed 410, 2017.
  • Xiao J, Mi W, Li L, Shi Y, Zhang H. High relapse rate and poor medication adherence in the Chinese population with schizophrenia: results from an observational survey in the people’s republic of China. Neuropsychiatr Dis Treat. 2015;11:1161–1167. doi:10.2147/NDT.S7236726056450
  • Emsley R, Oosthuizen PP, Koen L, Niehaus DJ, Martinez G. Symptom recurrence following intermittent treatment in first-episode schizophrenia successfully treated for two years: a 3-year open-label clinical study. J Clin Psychiatry. 2012;73(4):541–547. doi:10.4088/JCP.11m07138
  • Zipursky RB, Menezes NM, Streiner DL. Risk of symptom recurrence with medication dis- continuation in first-episode psychosis: a systematic review. Schizophr Res. 2014;152:408–414. doi:10.1016/j.schres.2013.08.00123972821
  • Dilla T, Ciudad A, Alvarez M. Systematic review of the economic aspects of nonadherence to antipsychotic medication in patients with schizophrenia. Patient Prefer Adherence. 2013;7:275–284. doi:10.2147/PPA.S4160923589681
  • Lindenmayer JP, Liu-Seifert H, Kulkarni PM, et al. Medication nonadherence and treatment outcome in patients with schizophrenia or schizoaffective disorder with a suboptimal prior response. J Clin Psychiatry. 2009;70(7):990–996. doi:10.4088/JCP.08m0422119497244
  • Leclerc E, Noto C, Bressan RA, Brietzke E. Determinants of adhe- rence to treatment in first-episode psychosis: a comprehensive review. Rev Bras Psiquiatr. 2015;37(2):168–176. doi:10.1590/1516-4446-2014-153925946398
  • Novick D, Montgomery W, Treuer T, Aguado J, Kraemer S, Haro JM. Relationship of insight with medication adherence and the impact on outcomes in patients with schizophrenia and bipolar disorder: results from a 1-year European outpatient observational study. BMC Psychiatry. 2015;15(1):1–8. doi:10.1186/s12888-015-0560-425609320
  • Shuler KM. Approaches to improve adherence to pharmacotherapy in patients with schizo phrenia. Patient Prefer Adherence. 2014;8:701–714. doi:10.2147/PPA.S5937124868149
  • Higashi K, Medic G, Littlewood KJ, Diez T, Granstrom O, De Hert M. Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review. Ther Adv Psychopharmacol. 2013;3(4):200–218. doi:10.1177/204512531247401924167693
  • Eticha T, Teklu A, Ali D, Solomon G, Alemayehu A. Factors associated with medication adherence among patients with schizophrenia in Mekelle, Northern Ethiopia. PLoS One. 2015;10(3):1–11. doi:10.1371/journal.pone.0120560
  • Velligan DI, Sajatovic M, Hatch A, Kramata P, Docherty JP. Why do psychiatric patients stop antipsychotic medication? a systematic review of reasons for nonadherence to medication in patients with severe mental illness. Patient Prefer Adherence. 2017;11:449–468. doi:10.2147/PPA.S12465828424542
  • Ramachandran AS, Ramanathan R, Praharaj SK, Kanradi H, Sharma PSVN. A cross- sectional, comparative study of insight in schizophrenia and bipolar patients in remission. Indian J Psychol Med. 2016;38(3):207–212. doi:10.4103/0253-717627335515
  • Mekonnen M, Boru B, Yohannis Z, Abebaw D, Birhanu A. Level of perceived social support and associated factors among people with schizophrenia attending outpatient department at amanuel mental specialized hospital. J Psychopharmacol. 2019;22:1–7. doi:10.4172/2378-5756.1000461
  • National Academy for Educational Reasearch. Theories of motivation. 2000 Available from: http://terms.naer.edu.tw/detail/1309154/ Accessed 410, 2017.
  • Ajzen I. The theory of planned behavior. Organ Behav Hum Decis Process. 1991;50:179–211. doi:10.1016/0749-5978(91)90020-T
  • Chang YT, Tao SG, Lu CL. Qualitative inquiry into motivators for maintaining medication adherence among Taiwanese with schizophrenia. Int J Ment Health Nurs. 2013;22(3):272–278. doi:10.1111/j.1447-0349.2012.00864.x22882876
  • Rungruangsiripan M, Sitthimongkol Y, Maneesriwongul W, Talley S, Vorapongsathorn T. Mediating role of illness representation among social support, therapeutic alliance, the experience of medication side effects, and medication adherence in persons with schizophrenia. Arch Psychiatr Nurs. 2011;25(4):269–283. doi:10.1016/j.apnu.2010.09.00221784285
  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-5. Washington: Am J Psychiatry; 2013.
  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR. Washington: Am J Psychiatry; 2000.
  • Startup M, Jackson MC, Bendix S. The concurrent validity of the Global Assessment of Functioning (GAF). Br J Clin Psychol. 2002;41(4):417–422. doi:10.1348/01446650276038753312437796
  • Chang TJ, Hwu HG, Wei FW. The inter-rater reliability of brief psychiatric rating scale (BPRS). Chin Soc Neurol Psychiatry Bull. 1986;12(1):29–36.
  • Waddell L, Taylor M. A new self-rating scale for detecting atypical or second-generation antipsychotic side effects. J Psychopharmacol. 2008;22(3):238–243. doi:10.1177/026988110708797618541624
  • Nystazaki M, Tsapakis E, Hadjulis M, Alevizopoulos G. Validation of the Glasgow Antipsychotic Side-Effect Scale (GASS) in Greece. J Child Psychol Psychiatry. 2014;1(4):1–6. doi:10.15406/jpcpy.2014.01.00024
  • Tracey TJ, Kokotovic AM. Factor structure of the working alliance inventory. J Consult Clin Psychol. 1989;1(3):207–210. doi:10.1037/1040-3590.1.3.207
  • Munder T, Wilmers F, Leonhart R, Linster HW, Barth J. Working Alliance Inventory-Short Revised (WAI-SR): psychometric properties in outpatients and inpatients. Clin Psychol Psychother. 2010;17(3):231–239. doi:10.1002/cpp.65820013760
  • Andrusyna TP, Tang TZ, DeRubeis RJ, Luborsky L. The factor structure of the Working Alliance Inventory in cognitive-behavioral therapy. J Psychother Pract Res. 2001;10(3):173–178.11402080
  • Yu DS, Lee DT, Woo J. Psychometric testing of the Chinese version of the Medical Outcomes Study Social Support survey (MOS-SSS-C). Res Nurs Health. 2004;27(2):135–143. doi:10.1002/nur.2000815042639
  • Alonso FA, Montes MA, Menendez VC, Pereira MG. Cultural adaptation and validation of the medical outcomes study social support survey questionnaire (MOS-SSS). Acta Med Port. 2006;20(6):525–534.
  • Yen CF, Yeh ML, Chong MY, Chung HH, Chen CS. A multidimensional assessment of insights in schizophrenic patients. Kaohsiung J Med Sci. 2001;17(5):253–260.11517864
  • Chan SC, Chan CC, Siu AM, Poon PK. Stage of change in self- management of chronic diseases: psychometric properties of the Chinese version of the University of Rhode Island Change Assessment (C-URICA) Scale. Rehabil Psychol. 2007;52(1):103–112. doi:10.1037/0090-5550.52.1.103
  • Thompson K, Kulkarni J, Sergejew AA. Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophr Res. 2000;42(3):241–247. doi:10.1016/S0920-9964(99)00130-910785582
  • Kao YC, Liu YP. Compliance and schizophrenia: the predictive potential of insight into illness, symptoms, and side effects. Compr Psychiatry. 2010;51(6):557–565. doi:10.1016/j.comppsych.2010.03.00720965300
  • Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986;51(6):1173–1182. doi:10.1037/0022-3514.51.6.11733806354
  • Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. New York: Guilford Press; 2013.
  • MacKinnon DP, Lockwood CM, Hoffman JM, West SG, Sheets V. A comparison of methods to test mediation and other intervening variable effects. Psychol Methods. 2002;7(1):83–104. doi:10.1037/1082-989X.7.1.8311928892
  • Preacher KJ, Hayes AF. SPSS and SAS procedures for estimating indirect effects in simple mediation models. Behav Res Methods Instrum Comput. 2004;36(4):717–731. doi:10.3758/BF0320655315641418
  • Sobel ME. Asymptotic confidence intervals for indirect effects in structural equation models. Sociol Methodol. 1982;13:290–312. doi:10.2307/270723
  • Abrar S, Shoka A, Arain N, Widuch-Mert C. Landing on the MARS! BJMP. 2012;5(3):9–14.
  • British Medical Journal. Correlation and regression. 2011 Available from: https://www.bmj.com/about-bmj/resources-readers/publications/statistics-square-one/11-correlation-and-regression Accessed 106, 2018.
  • Hill M, Crumlish N, Whitty P, et al. Nonadherence to medication four years after the first episode of psychosis and associated risk factors. Psychiatric Serv. 2010;61(2):189–192. doi:10.1176/ps.2010.61.2.189
  • Prochaska JO, Redding CA, Evers KE. The transtheoretical model and stages of change In: Glanz K, Barbara KR, Viswanath K, editors. Health Behavior: Theory, Research, and Practice. San Francisco: Jossey-Bass A Wiley Brand; 2015:125–148.
  • Fai EK, Anderson C, Ferreros V. Role of attitudes and intentions in predicting adherence to oral diabetes medications. Endocr Connect. 2017;6(2):63–70. doi:10.1530/EC-16-009328087609
  • Wu P, Liu N. Association between patients’ beliefs and oral antidiabetic medication adherence in a Chinese type 2 diabetic population. Patient Prefer Adherence. 2016;10:1161–1167. doi:10.2147/PPA.S10560027390519
  • Lin CY, Updegraff JA, Pakpour AH. The relationship between the theory of planned behavior and medication adherence in patients with epilepsy. Epilepsy Behav. 2016;61:231–236. doi:10.1016/j.yebeh.2016.05.03027390026
  • Ho CP, Lee TJF. An evaluation of medication adherence in hypertensive patients using the theory of planned behavior. Value Health. 2014;17(7):763. doi:10.1016/j.jval.2014.08.270
  • Jeng KS, Huang HK, Lee CF, Shao WC, Chang YF. The effect of a project to enhance drug compliance of psychiatric patients who live in remote mountainous areas. J Med Health. 2014;3(1):77–78.
  • Lin HH, Kuo YP, Lin ECL, Chen PS, Chen KC. A pilot study of the effect of an illness management group on patients with schizophrenia living in the community. J Nurs Healthcare Res. 2014;10(1):15–22.
  • Chien WT, Mui J, Gray R, Cheung E. Adherence therapy versus routine psychiatric care for people with schizophrenia spectrum disorders: a randomized controlled trial. BMC Psychiatry. 2016;16(1):1–14. doi:10.1186/s12888-016-0744-626739960
  • Cook PF, Emiliozzi S, Waters C, El DH. Effects of telephone counseling on antipsychotic adherence and emergency department utilization. Am J Manag Care. 2008;14(12):841–846.19067501
  • Schulz M, Gray R, Spiekermann A, Abderhalden C, Behrens J, Driessen M. Adherence therapy following an acute episode of schizophrenia: a multi-center randomized controlled trial. Schizophr Res. 2013;146(1):59–63. doi:10.1016/j.schres.2013.01.02823452506
  • Staring A, Van der Gaag M, Koopmans G, et al. Treatment adherence therapy in people with psychotic disorders: randomized controlled trial. Br J Psychiatry. 2010;197(6):448–455. doi:10.1192/bjp.bp.110.07728921119150
  • Chien WT, Mui JH, Cheung EF, Gray R. Effects of motivational interviewing-based adherence therapy for schizophrenia spectrum disorders: a randomized controlled trial. Trials. 2015;16(1):1–14. doi:10.1186/s13063-015-0785-z25971836
  • Stirratt MJ, Dunbar-Jacob J, Crane HM, et al. Self-report measures of medication adherence behavior: recommendations on optimal use. Transl Behav Med. 2015;5(4):470–482. doi:10.1007/s13142-015-0315-226622919
  • Shi L, Liu J, Fonseca V, Walker P, Kalsekar A, Pawaskar M. Correlation between adherence rates measured by MEMS and self-reported questionnaires: a meta-analysis. Health Qual Life Outcomes. 2010;8(1):1–7. doi:10.1186/1477-7525-8-9920053296