314
Views
11
CrossRef citations to date
0
Altmetric
Original Research

Non-Adherence to Pharmacotherapy: A Prospective Multicentre Study About Its Incidence and Its Causes Perceived by Chronic Pain Patients

ORCID Icon, ORCID Icon, & ORCID Icon
Pages 321-332 | Published online: 19 Feb 2020

References

  • World Health Organization. Adherence to Long-Term Therapies. Evidence for Action. Geneva, Switzerland: World Health Organization. 199; 2003.
  • Sampaio R, Pereira MG, Winck JC. A new characterization of adherence patterns to auto-adjusting positive airway pressure in severe obstructive sleep apnea syndrome: clinical and psychological determinants. Sleep Breath. 2013;17(4):1145–1158. doi:10.1007/s11325-013-0814-7
  • Dunbar-Jacob J, Mortimer-Stephens MK. Treatment adherence in chronic disease. J Clin Epidemiol. 2001;54(Suppl 1):S57–60. doi:10.1016/S0895-4356(01)00457-7
  • Timmerman L, Stronks DL, Groeneweg JG, Huygen FJ. Prevalence and determinants of medication non-adherence in chronic pain patients: a systematic review. Acta Anaesthesiol Scand. 2016;60(4):416–431.
  • Lehmann A, Aslani P, Ahmed R, et al. Assessing medication adherence: options to consider. Int J Clin Pharm. 2014;36(1):55–69. doi:10.1007/s11096-013-9865-x
  • Bond WS, Hussar DA. Detection methods and strategies for improving medication compliance. Am J Hosp Pharm. 1991;48(9):1978–1988.
  • Rosser BA, McCracken LM, Velleman SC, et al. Concerns about medication and medication adherence in patients with chronic pain recruited from general practice. Pain. 2011;152(5):1201–1205. doi:10.1016/j.pain.2011.01.053
  • Azevedo LF, Costa-Pereira A, Mendonça L, et al. Epidemiology of chronic pain: a population-based nationwide study on its prevalence, characteristics and associated disability in Portugal. Med Care. 2013;51(10):859–869. doi:10.1097/MLR.0b013e3182a53e4e
  • Vrijens B, De Geest S, Hughes DA, et al. A new taxonomy for describing and defining adherence to medications. Br J Clin Pharmacol. 2012;73(5):691–705. doi:10.1111/bcp.2012.73.issue-5
  • De Geest S, Zullig LL, Dunbar-Jacob J, et al. ESPACOMP Medication Adherence Reporting Guideline (EMERGE). Ann Intern Med. 2018;169(1):30–35. doi:10.7326/M18-0543
  • Lehane E, McCarthy G. Intentional and unintentional medication non-adherence: a comprehensive framework for clinical research and practice? A discussion paper. Int J Nurs Stud. 2007;44(8):1468–1477. doi:10.1016/j.ijnurstu.2006.07.010
  • Mukhtar O, Weinman J, Jackson SH. Intentional non-adherence to medications by older adults. Drugs Aging. 2014;31(3):149–157. doi:10.1007/s40266-014-0153-9
  • Gadkari AS, McHorney CA. Unintentional non-adherence to chronic prescription medications: how unintentional is it really? BMC Health Serv Res. 2012;12:98. doi:10.1186/1472-6963-12-98
  • Horne R, Chapman SCE, Parham R, et al. Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the Necessity-Concerns Framework. PLoS One. 2013;8(12):e80633. doi:10.1371/journal.pone.0080633
  • Leventhal H, Zimmerman R, Gutmann M. Compliance: a self-regulation perspective. In: Gentry D, editor. Handbook of Behaviour Medicine. New York: Pergamon Press; 1984:369–434.
  • Bardin L. Análise De Conteúdo. Lisboa: Edic¸ões; 1977:70.
  • International Association for the study of Pain. Revision of the International Classification of Diseases (ICD-11). [ cited 2017]; Available from: http://www.iasp-pain.org/Advocacy/icd.aspx?ItemNumber=5234&navItemNumber=5236. Accessed January 29, 2020.
  • Azevedo LF, Dias C, Agualusa L, Lemos L, Romão J. Translation, cultural adaptation and multicentric validation study of chronic pain screening and impact assessment instruments [Tradução, adaptação cultural e estudo multicêntrico de validação de instrumentos para rastreio e avaliação do impacto da dor crónica]. Dor. 2007;15(4):6–56.
  • Caraceni A, Cherny N, Fainsinger R, et al. Pain measurement tools and methods in clinical research in palliative care: recommendations of an Expert Working Group of the European Association of Palliative Care. J Pain Symptom Manage. 2002;23(3):239–255. doi:10.1016/S0885-3924(01)00409-2
  • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–370. doi:10.1111/acp.1983.67.issue-6
  • Mora PA, Berkowitz A, Contrada RJ, et al. Factor structure and longitudinal invariance of the medical adherence report scale-asthma. Psychol Health. 2011;26(6):713–727. doi:10.1080/08870446.2010.490585
  • Sampaio R, Azevedo LF, Dias CC, Horne R, Castro Lopes JM. Portuguese version of the Medication Adherence Report Scale (MARS-9): validation in a population of chronic pain patients. J Eval Clin Pract. 2019;25(2):346–352.
  • Azevedo LF, Costa-Pereira A, Mendonça L, et al. Epidemiology of chronic pain: a population-based nationwide study on its prevalence, characteristics and associated disability in Portugal. J Pain. 2012;13(8):773–783. doi:10.1016/j.jpain.2012.05.012
  • MacPherson RD. New directions in pain management. Drugs Today (Barc). 2002;38(2):135–145. doi:10.1358/dot.2002.38.2.668325
  • Broekmans S, Dobbels F, Milisen K, et al. Medication adherence in patients with chronic non-malignant pain: is there a problem? Eur J Pain. 2009;13(2):115–123. doi:10.1016/j.ejpain.2008.02.010
  • Kardas P, Lewek P, Matyjaszczyk M. Determinants of patient adherence: a review of systematic reviews. Front Pharmacol. 2013;4:91. doi:10.3389/fphar.2013.00091
  • Alsalman AJ, Smith WR. Expanding the framework of assessing adherence and medication-taking behavior. J Pain Palliat Care Pharmacother. 2013;27(2):114–124. doi:10.3109/15360288.2013.765532
  • Butow P, Sharpe L. The impact of communication on adherence in pain management. Pain. 2013;154(Suppl 1):S101–7. doi:10.1016/j.pain.2013.07.048
  • Cramer J, Mattson R. Monitoring compliance with antiepileptic drug therapy,In: Cramer J, Spilker B, editors. Patient Compliance in Medical Practice and Clinical Trials. New York: Raven Press; 1991.
  • Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet. 1996;348(9024):383–386. doi:10.1016/S0140-6736(96)01073-2
  • Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care. 2004;27(5):1218–1224. doi:10.2337/diacare.27.5.1218
  • Abughosh SM, Wang X, Serna O, et al. A pharmacist telephone intervention to identify adherence barriers and improve adherence among nonadherent patients with comorbid hypertension and diabetes in a medicare advantage plan. J Manag Care Spec Pharm. 2016;22(1):63–73. doi:10.18553/jmcp.2016.22.1.63
  • Benner JS, Glynn RJ, Mogun H, et al. Long-term persistence in use of statin therapy in elderly patients. JAMA. 2002;288(4):455–461. doi:10.1001/jama.288.4.455
  • Salt E, Hall L, Peden AR, et al. Psychometric properties of three medication adherence scales in patients with rheumatoid arthritis. J Nurs Meas. 2012;20(1):59–72. doi:10.1891/1061-3749.20.1.59
  • Woo AKM. Depression and anxiety in pain. Reviews in Pain. 2010;4(1):8–12. doi:10.1177/204946371000400103
  • Mardby AC, Akerlind I, Jorgensen T. Beliefs about medicines and self-reported adherence among pharmacy clients. Patient Educ Couns. 2007;69(1–3):158–164. doi:10.1016/j.pec.2007.08.011
  • Clifford S, Barber N, Horne R. Understanding different beliefs held by adherers, unintentional nonadherers, and intentional nonadherers: application of the necessity-concerns framework. J Psychosom Res. 2008;64(1):41–46. doi:10.1016/j.jpsychores.2007.05.004
  • Choudhry NK, Krumme AA, Ercole PM, et al. Effect of reminder devices on medication adherence: the REMIND randomized clinical trial. JAMA Intern Med. 2017;177(5):624–631.
  • Azevedo LF, Costa-Pereira A, Mendonça L, et al. A population-based study on chronic pain and the use of opioids in Portugal. PAIN®. 2013;154(12):2844–2852. doi:10.1016/j.pain.2013.08.022
  • Lin CC, Chou P-L, Wu S-L, et al. Long-term effectiveness of a patient and family pain education program on overcoming barriers to management of cancer pain. Pain. 2006;122(3):271–281. doi:10.1016/j.pain.2006.01.039
  • Mika J, Zychowska M, Makuch W, Rojewska E, Przewlocka B. Neuronal and immunological basis of action of antidepressants in chronic pain - clinical and experimental studies. Pharmacol Rep. 2013;65(6):1611–1621. doi:10.1016/S1734-1140(13)71522-6
  • Trouvin AP, Perrot S, Lloret-Linares C. Efficacy of venlafaxine in neuropathic pain: a narrative review of optimized treatment. Clin Ther. 2017;39(6):1104–1122. doi:10.1016/j.clinthera.2017.05.347
  • Uceyler N, Sommer C, Walitt B, Häuser W. WITHDRAWN: anticonvulsants for fibromyalgia. Cochrane Database Syst Rev. 2017;10:Cd010782.
  • Wehling M. Non-steroidal anti-inflammatory drug use in chronic pain conditions with special emphasis on the elderly and patients with relevant comorbidities: management and mitigation of risks and adverse effects. Eur J Clin Pharmacol. 2014;70(10):1159–1172. doi:10.1007/s00228-014-1734-6
  • Millan-Millan MJ, Reinoso-Barbero F, Díaz-Miguel MP, et al. [Clinical characteristics of children with chronic pain in a pediatric pain unit: oncologic pain versus non-oncologic pain]. An Pediatr (Barc). 2003;58(4):296–301. doi:10.1016/s1695-4033(03)78061-8
  • Gouvinhas C, Veiga D, Mendonça L, et al. Interventional pain management in multidisciplinary chronic pain clinics: a prospective multicenter cohort study with one-year follow-up. Pain Res Treat. 2017;2017:8402413.
  • Basch E. The missing voice of patients in drug-safety reporting. N Engl J Med. 2010;362(10):865–869. doi:10.1056/NEJMp0911494