Medication Adherence in Children with Asthma

References

• Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2163.
   PubMed Web of Science ®Google Scholar
• Warke TJ, Fitch PS, Brown V, et al. Exhaled nitric oxide correlates with airway eosinophils in childhood asthma. Thorax. 2002;57(5):383–387. doi:10.1136/thorax.57.5.383
   PubMed Web of Science ®Google Scholar
• Reddel HK, Bacharier LB, Bateman ED, et al. Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes. Am J Respir Crit Care Med. 2022;205(1):17–35. doi:10.1164/rccm.202109-2205PP
   PubMed Web of Science ®Google Scholar
• Zhang D, Zheng J. The burden of childhood asthma by age group, 1990–2019: a systematic analysis of global burden of disease 2019 data. Front Pediatrics. 2022;10:113.
   Web of Science ®Google Scholar
• Society BT. Scottish intercollegiate guidelines network. Br Guideline Management Asthma. 2016;58.
   Google Scholar
• Asthma. GIf. Global strategy for asthma management and prevention, 2023; 2023. Available from: www.ginasthma.org. Accessed February 15, 2024.
   Google Scholar
• Barnes PJ. Inhaled Corticosteroids. Pharmaceuticals. 2010;3(3):514–540. doi:10.3390/ph3030514
   Google Scholar
• Ducharme FM, Hicks GC. Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database Syst Rev. 2002;3:Cd002314. doi:10.1002/14651858.Cd002314
   Google Scholar
• O’Donoghue DB, Shields MD. A Structured Multidisciplinary Approach to Managing Difficult-to-Treat Asthma in Children. Severe Asthma Children Adolescents. 2020;97–112.
   Google Scholar
• Shields MD, McElnay J. Mobile video directly observed therapy can be used to improve at-home inhaler technique in children with asthma. ERJ Open Res. 2021;7(4):00463–2021. doi:10.1183/23120541.00463-2021
   PubMedGoogle Scholar
• Takaku Y, Kurashima K, Ohta C, et al. How many instructions are required to correct inhalation errors in patients with asthma and chronic obstructive pulmonary disease? Respir Med. 2017;123:110–115. doi:10.1016/j.rmed.2016.12.012
   PubMed Web of Science ®Google Scholar
• Paracha R, Lo DKH, Montgomery U, Ryan L, Varakantam V, Gaillard EA. Asthma medication adherence and exacerbations and lung function in children managed in Leicester primary care. Npj Primary Care Respiratory Med. 2023;33(1):12. doi:10.1038/s41533-022-00323-6
   PubMed Web of Science ®Google Scholar
• Gillette C, Rockich-Winston N, Kuhn JA, Flesher S, Shepherd M. Inhaler technique in children with asthma: a systematic review. Acad Pediatrics. 2016;16(7):605–615. doi:10.1016/j.acap.2016.04.006
   PubMed Web of Science ®Google Scholar
• Rehman N, Morais-Almeida M, Wu AC. Asthma across childhood: improving adherence to asthma management from early childhood to adolescence. j Allergy Clin Immunol Practice. 2020;8(6):1802–1807. e1.
   PubMed Web of Science ®Google Scholar
• Miles C, Arden-Close E, Thomas M, et al. Barriers and facilitators of effective self-management in asthma: systematic review and thematic synthesis of patient and healthcare professional views. Npj Primary Care Respir Med. 2017;27(1):57. doi:10.1038/s41533-017-0056-4
   PubMedGoogle Scholar
• de Groot EP, Kreggemeijer WJ, Brand PL. Getting the basics right resolves most cases of uncontrolled and problematic asthma. Acta Paediatrica. 2015;104(9):916–921. doi:10.1111/apa.13059
   PubMed Web of Science ®Google Scholar
• Engelkes M, Janssens HM, de Jongste JC, Sturkenboom MC, Verhamme KM. Medication adherence and the risk of severe asthma exacerbations: a systematic review. Eur Respir J. 2015;45(2):396–407. doi:10.1183/09031936.00075614
   PubMed Web of Science ®Google Scholar
• Normansell R, Kew KM, Stovold E. Interventions to improve adherence to inhaled steroids for asthma. Cochrane Database Syst Rev. 2017;2017(4). doi:10.1002/14651858.CD012226.pub2
   Web of Science ®Google Scholar
• Tan DJ, Bui DS, Dai X, et al. Does the use of inhaled corticosteroids in asthma benefit lung function in the long-term? A systematic review and meta-analysis. Eur Respir Rev. 2021;30(159):200185. doi:10.1183/16000617.0185-2020
   PubMed Web of Science ®Google Scholar
• Fielding S, Pijnenburg M, de Jongste JC, et al. Change in FEV(1) and Feno Measurements as Predictors of Future Asthma Outcomes in Children. Chest. 2019;155(2):331–341. doi:10.1016/j.chest.2018.10.009
   PubMed Web of Science ®Google Scholar
• Wang Z, Pianosi P, Keogh K, et al. The clinical utility of fractional exhaled nitric oxide (FeNO) in asthma management. Int J Med. 2017.
   Google Scholar
• Petsky HL, Kew KM, Chang AB. Exhaled nitric oxide levels to guide treatment for children with asthma. Cochrane Database Syst Rev. 2016.
   Google Scholar
• Zheng S, Yu Q, Zeng X, Sun W, Sun Y, Li M. The influence of inhaled corticosteroid discontinuation in children with well-controlled asthma. Medicine. 2017;96(35):e7848. doi:10.1097/md.0000000000007848
   PubMed Web of Science ®Google Scholar
• Tibble H, Chan A, Mitchell EA, et al. A data-driven typology of asthma medication adherence using cluster analysis. Sci Rep. 2020;10(1):14999. doi:10.1038/s41598-020-72060-0
   PubMed Web of Science ®Google Scholar
• Chan DS, Callahan CW, Sheets SJ, Moreno CN, Malone FJ. An Internet-based store-and-forward video home telehealth system for improving asthma outcomes in children. Am J Health Syst Pharm. 2003;60(19):1976–1981. doi:10.1093/ajhp/60.19.1976
   PubMed Web of Science ®Google Scholar
• Minai BA, Martin JE, Cohn RC. Results of a physician and respiratory therapist collaborative effort to improve long-term metered-dose inhaler technique in a pediatric asthma clinic. Respir Care. 2004;49(6):600–605.
   PubMedGoogle Scholar
• Giraud V, Roche N. Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability. Eur Respir J. 2002;19(2):246–251. doi:10.1183/09031936.02.00218402
   PubMed Web of Science ®Google Scholar
• Hogan AH, Carroll CL, Iverson MG, et al. Risk factors for pediatric asthma readmissions: a systematic review. J Pediatr. 2021;236:219–228. e11. doi:10.1016/j.jpeds.2021.05.015
   PubMed Web of Science ®Google Scholar
• Fassl BA, Nkoy FL, Stone BL, et al. The Joint Commission Children’s Asthma Care Quality Measures and Asthma Readmissions. Pediatrics. 2012;130(3):482–491. doi:10.1542/peds.2011-3318
   PubMed Web of Science ®Google Scholar
• Kennedy L, Gallagher G, Maxwell B, et al. Implementation of a Children’s Safe Asthma Discharge Care Pathway Reduces the Risk of Future Asthma Attacks in Children-A Retrospective Quality Improvement Report. Front Pediatr. 2022;10:865476. doi:10.3389/fped.2022.865476
   PubMed Web of Science ®Google Scholar
• Boushey HA, Sorkness CA, King TS, et al. Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med. 2005;352(15):1519–1528. doi:10.1056/NEJMoa042552
   PubMed Web of Science ®Google Scholar
• Pearce CJ, Chan AH, Jackson T, et al. Features of successful interventions to improve adherence to inhaled corticosteroids in children with asthma: a narrative systematic review. Pediatric Pulmonol. 2022;57(4):822–847. doi:10.1002/ppul.25838
   PubMed Web of Science ®Google Scholar
• Simoni AD, Horne R, Fleming L, Bush A, Griffiths C. What do adolescents with asthma really think about adherence to inhalers? Insights from a qualitative analysis of a UK online forum. BMJ Open. 2017;7(6):e015245. doi:10.1136/bmjopen-2016-015245
   PubMed Web of Science ®Google Scholar
• Gesinde B, Harry S. The use of motivational interviewing in improving medication adherence for individuals with asthma: a systematic review. Perspectives Public Health. 2018;138(6):329–335. doi:10.1177/1757913918786528
   PubMed Web of Science ®Google Scholar
• Kew KM, Malik P, Aniruddhan K, Normansell R. Shared decision‐making for people with asthma. Cochrane Database Syst Rev. 2017. doi:10.1002/14651858.CD012330.pub2
   Web of Science ®Google Scholar
• Volerman A, Balachandran U, Zhu M, et al. Evaluating inhaler education interventions for hospitalized children with asthma: a randomized controlled trial. Ann Allergy Asthma Immunol. 2023;131(2):217–223.e1. doi:10.1016/j.anai.2023.02.023
   PubMed Web of Science ®Google Scholar
• Baba R, Nakachi I, Masaki K, et al. Repetitive instructions at short intervals contribute to the improvement of inhalation technique. Asia Pac Allergy. 2020;10(2):e19. doi:10.5415/apallergy.2020.10.e19
   PubMed Web of Science ®Google Scholar
• Press VG, Arora VM, Trela KC, et al. Effectiveness of Interventions to Teach Metered-Dose and Diskus Inhaler Techniques. A Randomized Trial. Ann Am Thorac Soc. 2016;13(6):816–824. doi:10.1513/AnnalsATS.201509-603OC
   PubMed Web of Science ®Google Scholar
• Ardura‐Garcia C, Stolbrink M, Zaidi S, Cooper PJ, Blakey JD. Predictors of repeated acute hospital attendance for asthma in children: a systematic review and meta‐analysis. Pediatric Pulmonol. 2018;53(9):1179–1192. doi:10.1002/ppul.24068
   PubMed Web of Science ®Google Scholar
• Kew KM, Carr R, Crossingham I. Lay‐led and peer support interventions for adolescents with asthma. Cochrane Database Syst Rev. 2017;2017(4). doi:10.1002/14651858.CD012331.pub2
   Google Scholar
• Drouin O, Smyrnova A, Bétinjané N, Ducharme FM. Adherence to inhaled corticosteroids prescribed once vs twice daily in children with asthma. Ann Allergy Asthma Immunol. 2022;128(4):423–431.e3. doi:10.1016/j.anai.2022.01.018
   PubMed Web of Science ®Google Scholar
• Shimizu Y, Shiobara T, Arai R, Chibana K, Takemasa A. Real-life effectiveness of fluticasone furoate/vilanterol after switching from fluticasone/salmeterol or budesonide/formoterol therapy in patients with symptomatic asthma: relvar Ellipta for Real Asthma Control Study (RERACS study). J Thorac Dis. 2020;12(5):1877–1883. doi:10.21037/jtd-19-3913
   PubMed Web of Science ®Google Scholar
• Langley R, Thompson A, Westwood J, Urquhart D. P90 Once daily inhaled corticosteroid prescribing in paediatric asthma: a single centre retrospective cohort study. Thorax. 2018;73(Suppl 4):A151–A152. doi:10.1136/thorax-2018-212555.248
   PubMedGoogle Scholar
• Bender B, Wamboldt FS, O’Connor SL, et al. Measurement of children’s asthma medication adherence by self report, mother report, canister weight, and Doser CT. Ann Allergy Asthma Immunol. 2000;85(5):416–421. doi:10.1016/s1081-1206(10)62557-4
   PubMed Web of Science ®Google Scholar
• Makhecha S, Chan A, Pearce C, Jamalzadeh A, Fleming L. Novel electronic adherence monitoring devices in children with asthma: a mixed-methods study. BMJ Open Respir Res. 2020;7(1):e000589. doi:10.1136/bmjresp-2020-000589
   PubMed Web of Science ®Google Scholar
• Costello R. INCA. Available from: http://www.incadevice.com. Accessed May 11, 2022.
   Google Scholar
• Lee JR, Leo S, Liao S, et al. Electronic adherence monitoring devices for children with asthma: a systematic review and meta-analysis of randomised controlled trials. Int J Nursing Studies. 2021;122:104037. doi:10.1016/j.ijnurstu.2021.104037
   PubMed Web of Science ®Google Scholar
• Halterman JS, Riekert KA, Fagnano M, et al. Effect of the School-Based Asthma Care for Teens (SB-ACT) program on asthma morbidity: a 3-arm randomized controlled trial. J Asthma. 2022;59(3):494–506. doi:10.1080/02770903.2020.1856869
   PubMed Web of Science ®Google Scholar
• Pertzborn MC, Prabhakaran S, Hardy A, Baker D, Robinson MA, Hendeles L. Direct observed therapy of inhaled corticosteroids for asthma at school or daycare. Pediatr Allergy Immunol Pulmonol. 2018;31(4):226–229. doi:10.1089/ped.2018.0912
   PubMed Web of Science ®Google Scholar
• Shields MD, ALQahtani F, Rivey MP, McElnay JC. Mobile direct observation of therapy (MDOT)-A rapid systematic review and pilot study in children with asthma. PLoS One. 2018;13(2):e0190031. doi:10.1371/journal.pone.0190031
   PubMed Web of Science ®Google Scholar
• McIntire K, Weis B, Litwin Ye L, Krugman S. Feasibility of video observed therapy to support controller inhaler use among children in West Baltimore. J Asthma. 2021;1–12.
   PubMed Web of Science ®Google Scholar
• Ferris K. Optimising Inhaler Technique and Asthma Self-Management in Children and Young People. Royal Belfast Hospital for Sick Children; 2023.
   Google Scholar
• Gayle A, Tebboth A, Pang M, et al. Real-life prescribing of asthmatic treatments in UK general practice over time using 2014 BTS/SIGN steps. Npj Primary Care Respiratory Med. 2019;29(1):25. doi:10.1038/s41533-019-0137-7
   PubMedGoogle Scholar
• Mathioudakis AG, Tsilochristou O, Adcock IM, et al. ERS/EAACI statement on adherence to international adult asthma guidelines. Eur Respir Rev. 2021;30(161):210132. doi:10.1183/16000617.0132-2021
   PubMed Web of Science ®Google Scholar
• Yawn BP, Rank MA, Cabana MD, Wollan PC, Juhn YJ. Adherence to Asthma Guidelines in Children, Tweens, and Adults in Primary Care Settings: a Practice-Based Network Assessment. Mayo Clin Proc. 2016;91(4):411–421. doi:10.1016/j.mayocp.2016.01.010
   PubMed Web of Science ®Google Scholar