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ORIGINAL RESEARCH

Factors Related to Treatment Non-Adherence Among Caregivers of Pediatric and Adolescent Growth Hormone Deficiency Patients in Japan

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 607-622 | Received 26 Oct 2023, Accepted 06 Feb 2024, Published online: 07 Mar 2024

References

  • Tanaka T. Growth hormone treatment in Japan: past, present, and future. Pediatr Endocrinol Rev. 2012;10(Suppl 1):89–97.
  • Yokoya S, Tanaka T. The history of growth hormone treatment for GHD in Japan. Pediatr Endocrinol Rev. 2017;14(Suppl 1):201–208. doi:10.17458/per.vol14.2017.yt.historygrowthhormone
  • Ministry of Health, Labor and Welfare. Research on the practical infrastructure for the promotion of measures against chronic specific diseases in children. Policy research project on intractable diseases (policy research project on intractable diseases. study report. ministry of, health, labor and welfare, FY2008-–2010; 2024. Avaiable from: https://www.shouman.jp/research/pdf/23_2830/2830_18.pdf.Accessed February 15, 2024.
  • Lackner L, Jh Q, Witt S. Caregiving burden and special needs of parents in the care of their short-statured children – a qualitative approach. Front Endocrinol. 2023;14:1093983. doi:10.3389/fendo.2023.1093983
  • Tanaka T, Sato T, Yuasa A, et al. Patient preference for growth hormone treatment in Japanese children. Pediatr Int. 2021;63(10):1185–1191. doi:10.1111/ped.14760
  • Graham S, Neo S, Auyeung V, et al. What potentially modifiable factors are associated with treatment nonadherence in pediatric growth hormone deficiency? A quantitative study. Endocr Pract. 2021;27(2):146–151. doi:10.4158/EP-2020-0543
  • Nishinaga H, Kishimoto S, Nishi Y. Survey of growth hormone treatment in clinical practice and patient choice of device. Prog Med. 2015;35:1348–1352.
  • Kapoor R, Burke S, Sparrow S, et al. Monitoring of concordance in growth hormone therapy. Arch Dis Child. 2008;93:147–148. doi:10.1136/adc.2006.114249
  • Cutfield W, Derraik J, Gunn A, et al. Non-compliance with growth hormone treatment in children is common and impairs linear growth. PLoS One. 2011;6:e16223. doi:10.1371/journal.pone.0016223
  • Hartmann K, Ittner J, Müller-Rossberg E, et al. Growth hormone treatment adherence in prepubertal and pubertal children with different growth disorders. Horm Res Paediatr. 2013;80(1):1–5. doi:10.1159/000351800
  • Foo J, Maghnie M, Colao A, et al. Cost-consequence analysis of human recombinant growth hormone (r-hGH) treatment administered via different devices in children with growth hormone deficiency in Italy. Clinicoecon Outcomes Res. 2019;11:525–537. doi:10.2147/CEOR.S195265
  • Horne R. Compliance, adherence, and concordance: implications for asthma treatment. Chest. 2006;130(1):65S–72S. doi:10.1378/chest.130.1_suppl.65S
  • National Institutes for Health and Care Excellence. Medicines Adherence: Involving Patients in Decisions About Prescribed Medicines and Supporting Adherence. London: National Institutes for Health and Care Excellence; 2009.
  • Norgren S. Adherence remains a challenge for patients receiving growth hormone therapy. Pediatr Endocrinol Rev. 2009;6(Suppl 4):545–548.
  • Mohseni S, Heydari Z, Qorbani M, et al. Adherence to growth hormone therapy in children and its potential barriers. J Pediatr Endocrinol Metab. 2018;31(1):13–20. doi:10.1515/jpem-2017-0157
  • Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353(5):487–497. doi:10.1056/NEJMra050100
  • Graham S, Weinman J, Auyeung V. Identifying potentially modifiable factors associated with treatment non-adherence in paediatric growth hormone deficiency: a systematic review. Horm Res Paediatr. 2018;90(4):221–228. doi:10.1159/000493211
  • Manabu A, Daisuke S, Takahiro S, et al. Perception of adherence to daily human growth hormone treatments among pediatric and adolescent patients in japan: a cross-sectional survey of physicians and caregivers. Patient Prefer Adherence. 2022;10(16):3081–3094.
  • Fumio O, Takahashi Y, Tahara S, Ogawa Y, Højby Rasmussen M, Takano K. Similar safety and efficacy in previously treated adults with growth hormone deficiency randomized to once-weekly somapacitan or daily growth hormone. Clin Endocrinol. 2020;93(5):620–628. doi:10.1111/cen.14273
  • Tanaka T, Susumu Y, Hoshino Y, et al. Long-term safety and efficacy of daily recombinant human growth hormone treatment in Japanese short children born small for gestational age: final report from an open and multi-center study. Clin Pediatr Endocrinol. 2018;27(3):145–157. doi:10.1297/cpe.27.145
  • Gomez R, Ahmed SF, Maghnie M, et al. Treatment adherence to injectable treatments in pediatric growth hormone deficiency compared with injectable treatments in other chronic pediatric conditions: a systematic literature Review. Front Endocrinol. 2022;13:795224. doi:10.3389/fendo.2022.795224
  • Orso M, Polistena B, Granato S, et al. Pediatric growth hormone treatment in Italy: a systematic review of epidemiology, quality of life, treatment adherence, and economic impact. PLoS One. 2022;17(2):e0264403. doi:10.1371/journal.pone.0264403
  • Suka M, Yamauchi T, Sugimori H. Relationship between individual characteristics, neighbourhood contexts and help-seeking intentions for mental illness. BMJ Open. 2015;5(8):e008261. doi:10.1136/bmjopen-2015-008261
  • Ishikawa H, Takeuchi T, Yano E. Measuring functional, communicative, and critical health literacy among diabetic patients. Diabetes Care. 2008;31(5):874–879. doi:10.2337/dc07-1932
  • Goto E, Ishikawa H, Okuhara T, Kiuchi T. Relationship of health literacy with utilization of health-care services in a general Japanese population. Preven Med Rep. 2019;14:100811. doi:10.1016/j.pmedr.2019.01.015
  • Suka M, Odajima T, Kasai M, et al. The 14-item health literacy scale for Japanese adults (HLS-14). Environ Health Prev Med. 2013;18(5):407–415. doi:10.1007/s12199-013-0340-z
  • Giavoli C, Profka E, Giancola N, et al. Growth hormone therapy at the time of Covid-19 pandemic: adherence and drug supply issues. Eur J Endocrinol. 2020;183:L13–L15.
  • Tanaka M, Kawakami A, Maeda S, et al. Validity and reliability of the Japanese version of the morisky medication adherence scale-8 in patients with ulcerative colitis. Gastro Nur. 2021;44(1):31–38. doi:10.1097/SGA.0000000000000533
  • Furue M, Takeuchi S, Murota H. Poor adherence to oral and topical medication in 3096 dermatological patients as assessed by the morisky medication adherence scale-8. Br J Dermatol. 2015;172(1):272–275. doi:10.1111/bjd.13377
  • Ichiyama S, Ito M, Funasaka Y. Assessment of medication adherence and treatment satisfaction in Japanese patients with psoriasis of various severities. J Dermatol. 2018;45(6):727–731. doi:10.1111/1346-8138.14225
  • Ikeda N, Kono A. The relationship between health habits, medication adherence, kidney function, and QOL among kidney transplant patients. J Jpn Acad Nurs Sci. 2018;38(1):365–373. doi:10.5630/jans.38.365
  • Miyazaki M, Nakashima A, Nakamura Y, et al. Association between medication adherence and illness perceptions in atrial fibrillation patients treated with direct oral anticoagulants: an observational cross-sectional pilot study. PLoS One. 2018;13(9):e0204814. doi:10.1371/journal.pone.0204814
  • Sultan S, El-Hourani M, Rondeau E, et al. Categorizing factors of adherence to parenteral treatment in growth hormone deficiencies and hemophilia: what should be the targets for future research? Patient Prefer Adherence. 2018;12:2039–2063. doi:10.2147/PPA.S177624
  • Maggio M, Vergara B, Porcelli P, et al. Improvement of treatment adherence with growth hormone by easypod™ device experience of an Italian centre. Ital J Pediatr. 2018;44(1):113–121. doi:10.1186/s13052-018-0548-z
  • Morisky DE, Ang A, Krousel-Wood M, et al. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens. 2008;10(5):348–354. doi:10.1111/j.1751-7176.2008.07572.x
  • Beriowitz DR, Foy CG, Kazis LE, et al. Impact of intensive bIood pressure therapy on patient- reported outcomes. outcomes results from the SPRINT study (for the SPRINT study research group). N Engl J Med. 2017;377(8):733–744. doi:10.1056/NEJMoa1611179
  • Bress AP, Bellows BK, King J, et al. Cost-effectiveness of intensive versus standard bIood pressure control. N Engl J Med. 2017;377(8):745–755. doi:10.1056/NEJMsa1616035
  • Orimo H, Sato M, Kimur S, et al. Understanding the factors associated with initiation and adherence of osteoporosis medication in Japan: an analysis of patient perceptions. Osteoporos Sarcopenia. 2017;3:174–184. doi:10.1016/j.afos.2017.10.002
  • Levin JB, Aebi ME, Howland M, et al. The relationship between medication attitudes and medication adherence behavior in adults with bipolar disorder. J Nerv Ment Dis. 2020;208(2):87–93. doi:10.1097/NMD.0000000000001083
  • Axelsson M, Cliffordson C, Lunbach B, et al. The function of medication beliefs as mediators between personality traits and adherence behavior in people with asthma. Patient Prefer Adherence. 2013;7:1101–1109. doi:10.2147/PPA.S49725
  • Klinovszky A, Kiss IM, Papp-Zipernovszky O, et al. Associations of different adherences in patients with type 2 diabetes mellitus. Patient Prefer Adherence. 2019;13:395–407. doi:10.2147/PPA.S187080
  • Boateng GO, Neilands TB, Frongillo EA, et al. Best practices for developing and validating scales for health, social, and behavioral research: a primer. Front Public Health. 2018;11(6):149. doi:10.3389/fpubh.2018.00149
  • Columbia University – mailman School of Public Health. Exploratory Factor Analysis. Columbia University; 2023. Available from: https://www.publichealth.columbia.edu/research/population-health-methods/exploratory-factor-analysis.Accessed June 28, 2023.
  • Columbia University – mailman School of Public Health. K-Means Cluster Analysis. Columbia University; 2023. Available from: https://www.publichealth.columbia.edu/research/population-health-methods/k-means-cluster-analysis.Accessed June 28, 2023.
  • Japan marketing research association. ephmra code of conduct (Japanese edition). Japan marketing research association; 2018. Availablre from: https://www.jmra-net.or.jp/LinkClick.aspx?fileticket=L%2F3co0zdIpM%3D&tabid=466.Accessed June 28, 2021.
  • De Pedro S, Murrilo M, Salinas I, et al. Variability in adherence to rhGH treatment: socioeconomic causes and effect on children’s growth. Growth Hormon IGF Res. 2016;26:32–35. doi:10.1016/j.ghir.2015.12.002
  • Arrabal Vela MA, Garcia Gijon CP, Pascual Martin M, et al. Adherence to somatotropin treatment administered with an electronic device. Endocrinol Diabetes Nutr. 2018;65(6):314–318. doi:10.1016/j.endinu.2018.02.003
  • Lass N, Reinehr T. Low treatment adherence in pubertal children treated with thyroxin or growth hormone. Horm Res Paediatr. 2015;84(4):240–247. doi:10.1159/000437305
  • Aydın BK, Aycan Z, Şıklar Z, Berberoğlu M, Öcal G. Çetinkaya S, et al Adherence to growth hormone therapy: results of a multicenter study. Endocr Pract. 2014;20(1):46–51. doi:10.4158/EP13194.OR
  • Rosenfeld RG, Bakker B. Compliance and persistence in pediatric and adult patients receiving growth hormone therapy. Endocr Pract. 2008;14(2):143–154. doi:10.4158/EP.14.2.143
  • Bagnasco F, Di Iorgi N, Roveda A, et al. Prevalence and correlates of adherence in children and adolescents treated with growth hormone: a multicenter Italian study. Endocr Pract. 2017;23(8):929–941. doi:10.4158/EP171786.OR
  • Urakami T. Effectiveness of a smartphone application on medication adherence in children with short stature receiving GH therapy: a multicenter prospective cohort study (GTL-App). Clin Pediatr Endocrinol. 2021;30(2):85–92. doi:10.1297/cpe.30.85
  • Marini MG, Chesi P, Mazzanti L, et al. Stories of experiences of care for growth hormone deficiency: the CRESCERE project. Future Sci OA. 2016;2(1):FSO82. doi:10.4155/fso.15.82
  • Amereller F, Schillbach K, Schopohl J, et al. Adherence, attitudes and beliefs of growth hormone deficient patients – a questionnaire-based cohort study. Exp Clin Endocrinol Diabet. 2019;129(2):112–117. doi:10.1055/a-0956-1919
  • Sudore RL, Schillinger D. Interventions to improve care for patients with limited health literacy. J Clin Outcomes Manag. 2009;16(1):20–29.
  • Graham S, Quirke-McFarlane S, Auyeung V, et al. Interventions designed to improve adherence to growth hormone treatment for pediatric patients and their families: a narrative review. Pharmaceutics. 2022;14(11):2373. doi:10.3390/pharmaceutics14112373
  • Acerini CL, Segal D, Criseno S, et al. Shared decision-making in growth hormone therapy-indications for patient care. Front Endocrinol. 2018;9:1–14. doi:10.3389/fendo.2018.00688