Medicine possession ratio as proxy for adherence to antiepileptic drugs: prevalence, associations, and cost implications

References

• WHO (World Health Organization)EpilepsyGenevaWorld Health Organization2015 Available from: http://www.who.int/mediacentre/factsheets/fs999/en/index.htmlAccessed August 19, 2015
   Google Scholar
• ChristainsonALZwaneMEMangaPRosenEVenterAKrombergJGEpilepsy in rural South African children: prevalence, associated disability and managementS Afr Med J200090326226610853404
   PubMed Web of Science ®Google Scholar
• WagnerRGNgugiAKTwineRPrevalence and risk factors for active convulsive epilepsy in rural northeast South AfricaEpilepsy Res2014108478279124582322
   PubMed Web of Science ®Google Scholar
• BirbeckGLHaysRDCuiXVickreyBGSeizure reduction and quality of life improvements in people with epilepsyEpilepsia200243553553812027916
   PubMed Web of Science ®Google Scholar
• TiamkaoSKaewkiowNPranbulSfor Integrated Epilepsy Research GroupValidation of a seizure-related injury modelJ Neurol Sci20143361–211311524209899
   PubMed Web of Science ®Google Scholar
• NeiMBaglaRSeizure-related injury and deathCurr Neurol Neurosci Rep20077433534117618541
   PubMed Web of Science ®Google Scholar
• BellonMWalkerCPetersonCSeizure-related injuries and hospitalizations: self-report data from the 2010 Australian Epilepsy Longitudinal SurveyEpilepsy Behav201326171023201608
   PubMed Web of Science ®Google Scholar
• CamfieldCCamfieldPInjuries from seizures are a serious, persistent problem in childhood onset epilepsy: a population-based studySeizure201527808325891933
   PubMed Web of Science ®Google Scholar
• SabatéEAdherence to Long-term Therapies: Evidence for ActionGenevaWorld Health Organization2003
   Google Scholar
• VrijensBDe GeestSHughesDAfor ABC Project TeamA new taxonomy for describing and defining adherence to medicationsBr J Clin Pharmacol201273569170522486599
   PubMed Web of Science ®Google Scholar
• HugtenburgJGTimmersLEldersPJVervloetMvan DijkLDefinitions, variants, and causes of nonadherence with medication: a challenge for tailored interventionsPatient Prefer Adherence2013767568223874088
   PubMed Web of Science ®Google Scholar
• HednaKHäggSAndersson SundellKPetzoldMHakkarainenKMRefill adherence and self-reported adverse drug reactions and sub-therapeutic effects: a population-based studyPharmacoepidemiol Drug Saf201322121317132524127242
   PubMed Web of Science ®Google Scholar
• HovingaCAAsatoMRManjunathRAssociation of non-adherence to antiepileptic drugs and seizures, quality of life, and productivity: survey of patients with epilepsy and physiciansEpilepsy Behav200813231632218472303
   PubMed Web of Science ®Google Scholar
• JonesRMButlerJAThomasVAPevelerRCPrevettMAdherence to treatment in patients with epilepsy: associations with seizure control and illness beliefsSeizure200615750450816861012
   PubMed Web of Science ®Google Scholar
• CramerJAGlassmanMGRienziVThe relationship between poor medication compliance and seizuresEpilepsy Behav20023433834212609331
   PubMed Web of Science ®Google Scholar
• SamsonsenCReimersABråthenGHeldeGBrodtkorbENonadherence to treatment causing acute hospitalizations in people with epilepsy: an observational, prospective studyEpilepsia20145511e125e12825252007
   PubMed Web of Science ®Google Scholar
• LadnerTRMorganCDPomerantzDJDoes adherence to epilepsy quality measures correlate with reduced epilepsy-related adverse hospitalization: a retrospective experienceEpilepsia2015565e63e6725809720
   PubMed Web of Science ®Google Scholar
• ManjunathRDavisKLCandrilliSDEttingerABAssociation of antiepileptic drug nonadherence with risk of seizures in adults with epilepsyEpilepsy Behav200914237237819126436
   PubMed Web of Science ®Google Scholar
• SanderJWBellGSReducing mortality: an important aim of epilepsy managementJ Neurol Neurosurg Psychiatr200475334935114966142
   PubMed Web of Science ®Google Scholar
• FaughtEDuhMSWeinerJRGuérinACunningtonMCNonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM studyNeurology200871201572157818565827
   PubMed Web of Science ®Google Scholar
• FredianiFCannatàAPMagnoniAPeccarisiCBussoneGThe patient with medication overuse: clinical management problemsNeurol Sci200324Suppl 2s108s11112811605
   PubMed Web of Science ®Google Scholar
• StroupeKTMurrayMDStumpTECallahanCMAssociation between medication supplies and healthcare costs in older adults from an urban healthcare systemJ Am Geriatr Soc200048776076810894314
   PubMed Web of Science ®Google Scholar
• KingsmanKMelanderACarlstenAEkedahlANilssonJLRefill non-adherence to repeat prescriptions leads to treatment gaps or to high extra costsPharm World Sci2007291192417268941
   PubMedGoogle Scholar
• DavisKLCandrilliSDEdinHMPrevalence and cost of nonadherence with antiepileptic drugs in an adult managed care populationEpilepsia200849344645418031549
   PubMed Web of Science ®Google Scholar
• EttingerABManjunathRCandrilliSDDavisKLPrevalence and cost of non-adherence to anti-epileptic drugs in elderly patients with epilepsyEpilepsy Behav200914232432919028602
   PubMed Web of Science ®Google Scholar
• IugaAOMcGuireMJAdherence and health care costsRisk Manag Healthc Policy20147354424591853
   PubMedGoogle Scholar
• FaughtREWeinerJRGuérinACunningtonMCDuhMSImpact of nonadherence to antiepileptic drugs on health care utilization and costs: findings from the RANSOM studyEpilepsia200950350150919183224
   PubMed Web of Science ®Google Scholar
• YHEC/School of PharmacyUniversity of London2010Evaluation of the Scale, Causes and Costs of Waste Medicines Available from: http://discovery.ucl.ac.uk/1350234/1/Evaluation_of_NHS_Medicines_Waste_web_publication_version.pdfAccessed January 10, 2016
   Google Scholar
• ChenCCBlankRHChengSHMedication supply, healthcare outcomes and healthcare expenses: longitudinal analysis of patients with type 2 diabetes and hypertensionHealth policy2014117337438124795290
   PubMed Web of Science ®Google Scholar
• BriesacherBAAndradeSEFouayziHChanKAComparison of drug adherence rates among patients with seven different medical conditionsPharmacotherapy200828443744318363527
   PubMed Web of Science ®Google Scholar
• SweilehWMIhbeshehMSJararISSelf-reported medication adherence and treatment satisfaction in patients with epilepsyEpilepsy Behav201121330130521576040
   PubMed Web of Science ®Google Scholar
• LusićITitlićMEterovićDEpileptic patient compliance with prescribed medical treatment [abstract]Acta Med Croatica2005591131815813351
   PubMedGoogle Scholar
• AsawavichienjindaTSitthi-AmornCTanyanontWCompliance with treatment of adult epileptics in a rural district of ThailandJ Med Assoc Thai2003861465112678138
   PubMedGoogle Scholar
• HodgesJCTreadwellJMalphrusADTranXGGiardinoAPIdentification and prevention of antiepileptic drug noncompliance: the collaborative use of state-supplied pharmaceutical dataISRN Pediatr2014201473468924693446
   PubMedGoogle Scholar
• MantriPMedication adherence in adults with epilepsyPract Nurs2015264179184
   Google Scholar
• AndradeSEKahlerKHFrechFChanKAMethods for evaluation of medication adherence and persistence using automated databasesPharmacoepidemiol Drug Saf200615856557416514590
   PubMed Web of Science ®Google Scholar
• MarcumZAGurwitzJHColόn-EmericCHanlonJTPills and ills: methodologic issues in pharmacologic researchJ Am Geriatr Soc201563482983025900504
   PubMed Web of Science ®Google Scholar
• ParkHRascatiKLLawsonKABarnerJCRichardsKMMaloneDCAdherence and persistence to prescribed medication therapy among Medicare part D beneficiaries on dialysis: comparisons of benefit type and benefit phasesJ Manag Care Spec Pharm201420886287625062080
   PubMedGoogle Scholar
• ThierSLYu-IsenbergKSLeasBEIn chronic disease, nationwide data show poor adherence by patients to medication and by physicians to guidelinesManag Care2008172485718361259
   PubMedGoogle Scholar
• KarveSClevesMAHelmMHudsonTJWestDSMartinBCProspective validation of eight different adherence measures for use with administrative claims data among patients with schizophreniaValue Health200912698999519402852
   PubMed Web of Science ®Google Scholar
• SikkaRXiaFAubertREEstimating medication persistency using administrative claims dataAm J Manag Care200511744945716044982
   PubMed Web of Science ®Google Scholar
• OsterbergLBlaschkeTAdherence to medicationN Engl J Med2005353548749716079372
   PubMed Web of Science ®Google Scholar
• OANDA Corporationc1996–c2015Currency converter Available from: http://www.oanda.com/currency/converter/Accessed August 27, 2015
   Google Scholar
• Council for Medical Schemes, South Africa2010Prescribed minimum benefits (PMB’s) aim to provide you with continuous care Available from: http://www.medicalschemes.com/ReadNews.aspx?2Accessed February 01, 2015
   Google Scholar
• Council for Medical Schemes, South Africa1998Medical Schemes Act, 131 of 1998 Available from: https://www.medicalschemes.com/Content.aspx?130Accessed February 01, 2015
   Google Scholar
• EllisSMSteynHSPractical significance (effect sizes) versus or in combination with statistical significance (p-values)Manag Dynam20031245153
   Google Scholar
• EgenasiaCSteinbergaWJRaubenheimerJEBeliefs about medication, medication adherence and seizure control among adult epilepsy patients in Kimberley, South AfricaSA Fam Pract2015575326332
   Google Scholar
• KrauseSRVan RooyenFCVan VuurenMVJJenkinsLNon-compliance with treatment by epileptic patients at George Provincial HospitalSA Fam Pract200749914a14d
   Google Scholar
• GarnettWRAntiepileptic drug treatment: outcomes and adherencePharmacotherapy2000208 Pt 2191S199S10937819
   PubMed Web of Science ®Google Scholar
• MbubaCKNguguAKFeganGRisk factors associated with the epilepsy treatment gap in Kilifi, Kenya: a cross-sectional studyLancet Neurol201111868869622770914
   PubMed Web of Science ®Google Scholar
• KeikelameMJSwartzLLost opportunities to improve health literacy: observations in a chronic illness clinic providing care for patients with epilepsy in Cape Town South AfricaEpilepsy Behav2013261364123207515
   PubMed Web of Science ®Google Scholar
• BuckDJacobyABakerGAChadwickDWFactors influencing compliance with antiepileptic drug regimesSeizure19976287939153719
   PubMed Web of Science ®Google Scholar
• PaschalAMRushSESadlerTFactors associated with medication adherence in patients with epilepsy and recommendations for improvementEpilepsy Behav20143134635024257314
   PubMed Web of Science ®Google Scholar
• ShettyJKirkpatrickMGreeneSAdherence to anti-epileptic medication in children with epilepsy from a Scottish population cohortArch Dis Child201297Suppl 1A135
   Google Scholar
• TanXCMakmor-BakryMLauCLTajarudinFWRaymondAAFactors affecting adherence to antiepileptic drugs therapy in MalaysiaNeurol Asia2015203235241
   Web of Science ®Google Scholar
• FerrariCMMde SousaRMCastroLHMFactors associated with treatment non-adherence in patients with epilepsy in BrazilSeizure201322538438923478508
   PubMed Web of Science ®Google Scholar
• GurumurthyRChandaKSarmaGAn evaluation of factors affecting adherence to anti-epileptic drugs in patients with epilepsy: a cross-sectional studySingapore Med J Epub2016125
   Web of Science ®Google Scholar
• GabrWMShamsMEAdherence to medication among outpatient adolescents with epilepsySaudi Pharm J2015231334025685041
   PubMed Web of Science ®Google Scholar
• BautistaREDRundle-GonzalezVEffects of antiepileptic drug characteristics on medication adherenceEpilepsy Behav201223443744122405862
   PubMed Web of Science ®Google Scholar
• RolnickSJPawloskiPAHedblomBDAscheSEBruzekRJPatient characteristics associated with medication adherenceClin Med Res2013112546523580788
   PubMedGoogle Scholar
• CooperJKLoveDWRaffoulPRIntentional prescription nonadherence (noncompliance) by the elderlyJ Am Geriatr Soc19823053293337077010
   PubMed Web of Science ®Google Scholar
• ManteuffelMWilliamsSChenWVerbruggeRRPittmanDGSteinkellnerAInfluence of patient sex and gender on medication use, adherence, and prescribing alignment with guidelinesJ Womens Health (Larchmt)201423211211924206025
   PubMed Web of Science ®Google Scholar
• HardenCThomasSVTomsonTEpilepsy in WomenOxfordJohn Wiley & Sons2013
   Google Scholar
• AhmedRAslaniPImpact of gender on adherence to therapyJ Malta College Pharm Pract2014202123
   Google Scholar
• BakerGAJacobyABuckDStalgisCMonnetDQuality of life of people with epilepsy: a European studyEpilepsia19973833533629070599
   PubMed Web of Science ®Google Scholar
• ZeberJECopelandLAPughMJVariation in antiepileptic drug adherence among older patients with new-onset epilepsyAnn Pharmacother201044121896190421045168
   PubMed Web of Science ®Google Scholar
• PeruccaETomsonTThe pharmacological treatment of epilepsy in adultsLancet Neurol201110544645621511198
   PubMed Web of Science ®Google Scholar
• UthmanBMExtended-release antiepilepsy drugs: review of the effects of once-daily dosing on tolerability, effectiveness, adherence, quality of life, and patient preferenceUS Neurol20141013037
   Google Scholar
• Council for Medical Schemes, South AfricaMedical Schemes Act, 1998 (Act 131 of 1998). Regulations made in terms of the Medical Scheme Act, 1998 therapeutic algorithms for chronic conditions. (Notice 1402)Government Gazette20032553753111
   Google Scholar
• JallonPPicardFBodyweight gain and anticonvulsants: a comparative reviewDrug Saf2001241396997811735653
   PubMed Web of Science ®Google Scholar
• MarcumZAGelladWFMedication adherence to multi-drug regimensClin Geriatr Med201228228730022500544
   PubMed Web of Science ®Google Scholar
• SaadatZNikdoustFAerab-SheibaniHAdherence to antihypertensives in patients with comorbid conditionNephrourol Mon20157416
   Google Scholar
• McAuleyJWMcFaddenLSElliottJOShnekerBFAn evaluation of self-management behaviors and medication adherence in patients with epilepsyEpilepsy Behav200813463764118656553
   PubMed Web of Science ®Google Scholar
• WHO (World Health Organization)2016Global Health Expenditure Database Available from: http://apps.who.int/nha/database/ViewData/Indicators/enAccessed January 28, 2016
   Google Scholar
• Council for Medical Schemes, South Africa2013 Available from: https://www.medicalschemes.com/files/Annual%20Reports/f0868c30e186Z.htmlAccessed January 28, 2016
   Google Scholar