Association of Retinal Neurovascular Impairment with Disease Severity in Patients with Major Depressive Disorder: An Optical Coherence Tomography Angiography Study

References

• Malhi GS, Mann JJ. Depression. Lancet. 2018;392(10161):2299–2312. doi:10.1016/S0140-6736(18)31948-2
   PubMed Web of Science ®Google Scholar
• Lu J, Xu X, Huang Y, et al. Prevalence of depressive disorders and treatment in China: a cross-sectional epidemiological study. Lancet Psychiatry. 2021;8(11):981–990. doi:10.1016/S2215-0366(21)00251-0
   PubMed Web of Science ®Google Scholar
• McCarron RM, Shapiro B, Rawles J, Luo J. Depression. Ann Intern Med. 2021;174(5):ITC65–ITC80. doi:10.7326/AITC202105180
   PubMed Web of Science ®Google Scholar
• Zhang FF, Peng W, Sweeney JA, Jia ZY, Gong QY. Brain structure alterations in depression: psychoradiological evidence. CNS Neurosci Ther. 2018;24(11):994–1003. doi:10.1111/cns.12835
   PubMed Web of Science ®Google Scholar
• London A, Benhar I, Schwartz M. The retina as a window to the brain-from eye research to CNS disorders. Nat Rev Neurol. 2013;9(1):44–53. doi:10.1038/nrneurol.2012.227
   PubMed Web of Science ®Google Scholar
• Spaide RF, Fujimoto JG, Waheed NK, Sadda SR, Staurenghi G. Optical coherence tomography angiography. Prog Retin Eye Res. 2018;64:1–55. doi:10.1016/j.preteyeres.2017.11.003
   PubMed Web of Science ®Google Scholar
• Kalenderoglu A, Çelik M, Sevgi-Karadag A, Egilmez OB. Optic coherence tomography shows inflammation and degeneration in major depressive disorder patients correlated with disease severity. J Affect Disord. 2016;204:159–165. doi:10.1016/j.jad.2016.06.039
   PubMed Web of Science ®Google Scholar
• Liu Y, Chen J, Huang L, Yan S, Gao D, Yang F. Association between changes in the retina with major depressive disorder and sleep quality. J Affect Disord. 2022;311:548–553. doi:10.1016/j.jad.2022.05.074
   PubMed Web of Science ®Google Scholar
• LeGates TA, Altimus CM, Wang H, et al. Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 2012;491:594–598. doi:10.1038/nature11673
   PubMed Web of Science ®Google Scholar
• LeGates TA, Fernandez DC, Hattar S. Light as a central modulator of circadian rhythms, sleep and affect. Nat Rev Neurosci. 2014;15(7):443–454. doi:10.1038/nrn3743
   PubMed Web of Science ®Google Scholar
• Fernandez DC, Fogerson PM, Lazzerini Ospri L, et al. Light affects mood and learning through distinct retina-brain pathways. Cell. 2018;175(1):71–84.e18. doi:10.1016/j.cell.2018.08.004
   PubMed Web of Science ®Google Scholar
• Huang L, Xi Y, Peng Y, et al. A visual circuit related to habenula underlies the antidepressive effects of light therapy. Neuron. 2019;102(1):128–142.e8. doi:10.1016/j.neuron.2019.01.037
   PubMed Web of Science ®Google Scholar
• Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol. 1967;6(4):278–296. doi:10.1111/j.2044-8260.1967.tb00530.x
   PubMedGoogle Scholar
• Zimmerman M, Thompson JS, Diehl JM, Balling C, Kiefer R. Is the DSM-5 anxious distress specifier interview a valid measure of anxiety in patients with generalized anxiety disorder: a comparison to the Hamilton anxiety scale. Psychiatry Res. 2020;286:112859. doi:10.1016/j.psychres.2020.112859
   PubMed Web of Science ®Google Scholar
• Nasreddine ZS, Phillips NA, Bédirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53(4):695–699. doi:10.1111/j.1532-5415.2005.53221.x
   PubMed Web of Science ®Google Scholar
• Bastien CH, Vallières A, Morin CM. Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med. 2001;2(4):297–307. doi:10.1016/s1389-9457(00)00065-4
   PubMed Web of Science ®Google Scholar
• Jia Y, Tan O, Tokayer J, et al. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express. 2012;20(4):4710–4725. doi:10.1364/OE.20.004710
   PubMed Web of Science ®Google Scholar
• Liu X, Lai S, Ma S, et al. Development of a novel retina−based diagnostic score for early detection of major depressive disorder: an interdisciplinary view. Front Psychiatry. 2022;13:897759. doi:10.3389/fpsyt.2022.897759
   PubMed Web of Science ®Google Scholar
• Schönfeldt-Lecuona C, Schmidt A, Kregel T, et al. Retinal changes in patients with major depressive disorder - A controlled optical coherence tomography study. J Affect Disord. 2018;227:665–671. doi:10.1016/j.jad.2017.11.077
   PubMed Web of Science ®Google Scholar
• Greaney JL, Saunders EFH, Santhanam L, Alexander LM. Oxidative stress contributes to microvascular endothelial dysfunction in men and women with major depressive disorder. Circ Res. 2019;124(4):564–574. doi:10.1161/CIRCRESAHA.118.313764
   PubMed Web of Science ®Google Scholar
• Smith PJ, Blumenthal JA, Hinderliter AL, Watkins LL, Hoffman BM, Sherwood A. Microvascular endothelial function and neurocognition among adults with major depressive disorder. Am J Geriatr Psychiatry. 2018;26(10):1061–1069. doi:10.1016/j.jagp.2018.06.011
   PubMed Web of Science ®Google Scholar
• Nishimura Y, Hara H, Kondo M, Hong S, Matsugi T. Oxidative stress in retinal diseases. Oxid Med Cell Longev. 2017;2017:4076518. doi:10.1155/2017/4076518
   PubMed Web of Science ®Google Scholar
• Masuda T, Shimazawa M, Hara H. retinal diseases associated with oxidative stress and the effects of a free radical scavenger (Edaravone). Oxid Med Cell Longev. 2017;2017:9208489. doi:10.1155/2017/9208489
   PubMed Web of Science ®Google Scholar
• Castelli V, Paladini A, d’Angelo M, et al. Taurine and oxidative stress in retinal health and disease. CNS Neurosci Ther. 2021;27(4):403–412. doi:10.1111/cns.13610
   PubMed Web of Science ®Google Scholar
• Wu H, Lu B, Zhang Y, Li T. Differences in prefrontal cortex activation in Chinese college students with different severities of depressive symptoms: a large sample of functional near-infrared spectroscopy (fNIRS) findings. J Affect Disord. 2024;350:521–530. doi:10.1016/j.jad.2024.01.044
   PubMed Web of Science ®Google Scholar
• Rensma SP, van Sloten TT, Launer LJ, Stehouwer CDA. Cerebral small vessel disease and risk of incident stroke, dementia and depression, and all-cause mortality: a systematic review and meta-analysis. Neurosci Biobehav Rev. 2018;90:164–173. doi:10.1016/j.neubiorev.2018.04.003
   PubMed Web of Science ®Google Scholar
• Geerling CF, Terheyden JH, Langner SM, et al. Changes of the retinal and choroidal vasculature in cerebral small vessel disease. Sci Rep. 2022;12(1):3660. doi:10.1038/s41598-022-07638-x
   PubMed Web of Science ®Google Scholar
• Cabrera DeBuc D, Somfai GM, Koller A. Retinal microvascular network alterations: potential biomarkers of cerebrovascular and neural diseases. Am J Physiol Heart Circ Physiol. 2017;312(2):H201–H212. doi:10.1152/ajpheart.00201.2016
   PubMed Web of Science ®Google Scholar
• Han LKM, Dinga R, Hahn T, et al. Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group. Mol Psychiatry. 2021;26(9):5124–5139. doi:10.1038/s41380-020-0754-0
   PubMed Web of Science ®Google Scholar
• Labaka A, Goñi-Balentziaga O, Lebeña A, Pérez-Tejada J. Biological sex differences in depression: a systematic review. Biol Res Nurs. 2018;20(4):383–392. doi:10.1177/1099800418776082
   PubMed Web of Science ®Google Scholar
• Birur B, Amrock EM, Shelton RC, Li L. Sex differences in the peripheral immune system in patients with depression. Front Psychiatry. 2017;8:108. doi:10.3389/fpsyt.2017.00108
   PubMed Web of Science ®Google Scholar
• Myoraku A, Lang A, Taylor CT, et al. Age-dependent brain morphometry in major depressive disorder. Neuroimage Clin. 2022;33:102924. doi:10.1016/j.nicl.2021.102924
   PubMed Web of Science ®Google Scholar
• van der Heide FCT, Steens ILM, Geraets AFJ, et al. Association of retinal nerve fiber layer thickness, an index of neurodegeneration, with depressive symptoms over time. JAMA Network Open. 2021;4(11):e2134753. doi:10.1001/jamanetworkopen.2021.34753
   PubMed Web of Science ®Google Scholar
• Zhang X, Olson DJ, Le P, Lin FC, Fleischman D, Davis RM. The association between glaucoma, anxiety, and depression in a large population. Am J Ophthalmol. 2017;183:37–41. doi:10.1016/j.ajo.2017.07.021
   PubMed Web of Science ®Google Scholar
• Berchuck S, Jammal A, Mukherjee S, Somers T, Medeiros FA. Impact of anxiety and depression on progression to glaucoma among glaucoma suspects. Br J Ophthalmol. 2021;105(9):1244–1249. doi:10.1136/bjophthalmol-2020-316617
   PubMed Web of Science ®Google Scholar
• Jain NS, Ruan CW, Dhanji SR, Symes RJ. Psychotropic drug-induced glaucoma: a practical guide to diagnosis and management. CNS Drugs. 2021;35(3):283–289. doi:10.1007/s40263-020-00790-w
   PubMed Web of Science ®Google Scholar
• Palagini L, Cipollone G, Masci I, et al. Insomnia symptoms predict emotional dysregulation, impulsivity and suicidality in depressive bipolar II patients with mixed features. Compr Psychiatry. 2019;89:46–51. doi:10.1016/j.comppsych.2018.12.009
   PubMed Web of Science ®Google Scholar
• Yildiz M, Alim S, Batmaz S, et al. Duration of the depressive episode is correlated with ganglion cell inner plexifrom layer and nasal retinal fiber layer thicknesses: optical coherence tomography findings in major depression. Psychiatry Res Neuroim. 2016;251:60–66. doi:10.1016/j.pscychresns.2016.04.011
   PubMed Web of Science ®Google Scholar