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ORIGINAL RESEARCH

Clinical Profiles of Cardiovascular Diseases and Predictors of Outcome of Hospitalization in a Tertiary Teaching Hospital, Ethiopia: A Prospective Observational Study

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Pages 69-83 | Received 07 Jul 2023, Accepted 19 Sep 2023, Published online: 29 Sep 2023

References

  • Gersh BJ, Sliwa K, Mayosi BM, Yusuf S. Novel therapeutic concepts: the epidemic of cardiovascular disease in the developing world: global implications. Eur Heart J. 2010;31(6):642–648. doi:10.1093/eurheartj/ehq030
  • Roth GA, Mensah GA, Johnson CO, et al. Global burden of cardiovascular diseases and risk factors, 1990–2019: update from the GBD 2019 study. J Am Coll Cardiol. 2020;76(25):2982–3021. doi:10.1016/j.jacc.2020.11.010
  • Zühlke L, Sliwa K, Naidoo P, et al. Cardiovascular medicine and research. Nat Rev Cardiol. 2019;16(11):642–644. doi:10.1038/s41569-019-0269-z
  • Keates AK, Mocumbi AO, Ntsekhe M, Sliwa K, Stewart S. Cardiovascular disease in Africa: epidemiological profile and challenges. Nat Publ Gr. 2017;14(5):273–293. doi:
  • Brodmann M, Cahill TJ, Hil DP, et al. Global burden of cardiovascular diseases. J Am Coll Cardiol. 2020;76(25):2982–3021.
  • Nyirenda MJ. Non-communicable diseases in sub-Saharan Africa: understanding the drivers of the epidemic to inform intervention strategies. Int Health. 2016;8(3):157–158. doi:10.1093/inthealth/ihw021
  • Mensah GA, Roth GA, Sampson UKA, et al. Mortality from cardiovascular diseases in sub-Saharan Africa, 1990–2013: a systematic analysis of data from the Global Burden of Disease Study 2013. Cardiovasc J Afr. 2015;26(2):S6–S10. doi:10.5830/CVJA-2015-036
  • Ntusi NAB, Mayosi BM. Epidemiology of heart failure in sub-Saharan Africa. Expert Rev Cardiovasc Ther. 2009;7(2):160–180. doi:10.1586/14779072.7.2.169
  • World Health Organization. International statistical classification of diseases and related health problems, 10th revision ICD-10: tabular list. World Health Organization; 2016:332–345. Available from: http://www.who.int/classifications/icd/icdonlineversions/en/. Accessed September 26, 2023.
  • Damasceno A, Mayosi BM, Sani M, et al. The causes, treatment, and outcome of acute heart failure in 1006 Africans from 9 countries. Arch Intern Med. 2012;172(18):1386–1394. doi:10.1001/archinternmed.2012.3310
  • Woldeyes E, Zewdu H, Abera H, et al. Clinical characteristics and in hospital outcome of acute heart failure: a five-year experience at a tertiary care hospital in Ethiopia. Ethiopian Med J. 2020;58(1):21–28.
  • Araya Giday EW, Weldeyes E. Trends in cardiovascular disease over time: a 30-year retrospective analysis of medical-ICU admissions. Ethiop Med J. 2015;53(3):133–139.
  • Kariuki JK, Stuart-shor EM, Leveille SG, Hayman LL, Israel B, Medical D. Methodological challenges in estimating trends and burden of cardiovascular disease in Sub-Saharan Africa. Cardiol Res Pract. 2015;2015. doi:10.1155/2015/921021
  • Yadeta D, Guteta S, Alemayehu B, et al. Spectrum of cardiovascular diseases in six main referral hospitals of Ethiopia. Heart Asia. 2017;9(1):1–5. doi:10.1136/heartasia-2016-010766
  • Abdissa SG, Oli K, Feleke Y, Goshu DY, Begna DM, Tafese A. Spectrum of cardiovascular diseases among Ethiopian patients at Tikur Anbessa Specialized University Teaching Hospital, Addis Ababa. Ethiop Med J. 2014;52(1):9–17.
  • Fenta EH, Sisay BG, Gebreyesus SH, Endris BS. Trends and causes of adult mortality from 2007 to 2017 using verbal autopsy method, Addis Ababa, Ethiopia. BMJ Open. 2021;11(11):1–8. doi:10.1136/bmjopen-2020-047095
  • Maru M. The changing pattern of cardiovascular diseases in Ethiopia. East Afr Med J. 1993;70(12):772–776.
  • Abraham G. Pattern of cardiovascular diseases among adult hospitalized Ethiopians. Ethiop Med J. 1982;20:63–68.
  • Kengne AP, Ntyintyane LM, Mayosi BM. Review Article A systematic overview of prospective cohort studies of cardiovascular disease in sub-Saharan Africa. Cardiovasc J Afr. 2012;23(2):103–112. doi:10.5830/CVJA-2011-042
  • Etyang AO, Scott G, Anthony J, et al. Medical causes of admissions to hospital among adults in Africa: a systematic review Anthony. Glob Heal Action. 2013;6(1):19090. doi:10.3402/gha.v6i0.19090
  • Hailu A, Gidey K, Ebrahim MM, et al. Patterns of medical admissions and predictors of mortality in ayder comprehensive Specialized Hospital, Northern Ethiopia: a prospective observational study. Int J Gen Med. 2023;16:243–257. doi:10.2147/IJGM.S385578
  • McKee PA, Castelli WP, McNamara PM, Kannel WB. The natural history of congestive heart failure: the Framingham Study. N Engl J Med. 1971;285(26):1441–1446. doi:10.1056/nejm19711223285260
  • Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American college of cardiology/American heart association task force on practice guidelines. Circulation. 2014;129(23):2440–2492. doi:10.1161/CIR.0000000000000029
  • Moran A, Forouzanfar M, Sampson U, Chugh S, Feigin V, Mensah G. ScienceDirect the epidemiology of cardiovascular diseases in Sub-Saharan Africa: the Global Burden of Diseases, Injuries and Risk Factors 2010 Study. Prog Cardiovasc Dis. 2013;56(3):234–239. doi:10.1016/j.pcad.2013.09.019
  • Habte B, Alemseged F, Tesfaye D. The pattern of cardiac diseases at the Cardiac Clinic of Jimma University Specialised Hospital, South West Ethiopia. Ethiop J Health Sci. 2011;20(2). doi:10.4314/ejhs.v20i2.69435
  • Familoni OB, Olunuga TO, Olufemi BW. A clinical study of pattern and factors affecting outcome in Nigerian patients with advanced heart failure. Cardiovasc J Afr. 2007;18(5):308–311.
  • Zannad F, Mebazaa A, Juillière Y, et al. Clinical profile, contemporary management and one-year mortality in patients with severe acute heart failure syndromes: the EFICA study. Eur J Heart Fail. 2006;8(7):697–705. doi:10.1016/j.ejheart.2006.01.001
  • Amusa GA. Cardiovascular disease: a Global Epidemic extending into Sub-Saharan Africa. A Review of Literature. Jos J Med. 2002;6(2):6–12.
  • Sliwa K, Wilkinson D, Hansen C, et al. Spectrum of heart disease and risk factors in a black urban population in South Africa (the Heart of Soweto Study): a cohort study. Lancet. 2008;371(9616):915–922. doi:10.1016/S0140-6736(08)60417-1
  • Vancheri F, Tate AR, Henein M, et al. Time trends in ischaemic heart disease incidence and mortality over three decades (1990–2019) in 20 Western European countries: systematic analysis of the Global Burden of Disease Study 2019. Eur J Prev Cardiol. 2022;29(2):396–403. doi:10.1093/eurjpc/zwab134
  • Fox CS, Evans JC, Larson MG, Kannel WB, Levy D. Temporal trends in coronary heart disease mortality and sudden cardiac death from 1950 to 1999: the Framingham Heart Study. Circulation. 2004;110(5):522–527. doi:10.1161/01.CIR.0000136993.34344.41
  • Oyoo GO, Ogola EN. Clinical and socio demographic aspects of congestive heart failure patients at Kenyatta National Hospital, Nairobi. East Afr Med J. 1999;76(1):23.
  • Tsega TA, Demissei BG. A systematic review of epidemiology, treatment and prognosis of heart failure in adults in Ethiopia. J Cardiovasc Med. 2018;19(3):91–97. doi:10.2459/JCM.0000000000000617
  • Mendez GF, Cowie MR. The epidemiological features of heart failure in developing countries: a review of the literature. Int J Cardiol. 2001;80(2–3):213–219. doi:10.1016/S0167-5273(01)00497-1
  • Mamo Y, Oli K. Trends of acute myocardial infarction admissions over a decade, Tikur Anbessa Hospital. Ethiop Med J. 2001;39(3):193–202.
  • Adem A, Abebe S, Hailu A, Feleke B, Berhe M, Atsibeha MDV. Heart diseases in North Ethiopia pattern of echocardiographic abnormalities among adult cardiac patients - an experience from Ayder hospital of Mekelle University. Ethiop Med J. 2014;52(4):173–183.
  • Tantchou Tchoumi JC, Ambassa JC, Kingue S, et al. Occurrence, aetiology and challenges in the management of congestive heart failure in sub-Saharan Africa: experience of the Cardiac Centre in Shisong, Cameroon. Pan Afr Med J. 2011;8688:1–7.
  • Stewart S, Wilkinson D, Hansen C, et al. Predominance of heart failure in the heart of Soweto study cohort: emerging challenges for urban African communities. Circulation. 2008;118(23):2360–2367. doi:10.1161/CIRCULATIONAHA.108.786244
  • Appiah LT, Sarfo FS, Agyemang C, et al. Current trends in admissions and outcomes of cardiac diseases in Ghana. Clin Cardiol. 2017;40(10):783–788. doi:10.1002/clc.22753
  • Mandi DG, Bamouni J, Yaméogo RA, et al. Spectrum of heart failure in sub-saharan Africa: data from a tertiary hospital-based registry in the eastern center of Burkina Faso. Pan Afr Med J. 2020;36:1–11. doi:10.11604/pamj.2020.36.30.19321
  • Gemechu T, Mahmoud H, Parry EHO, Phillips DIW, Yacoub MH. Community-based prevalence study of rheumatic heart disease in rural Ethiopia. Eur J Prev Cardiol. 2017;24(7):717–723. doi:10.1177/2047487316687104
  • Zilla P, Yacoub M, Zühlke L, et al. Global unmet needs in cardiac surgery. Glob Heart. 2018;13(4):293–303. doi:10.1016/j.gheart.2018.08.002
  • Bloomfield GS, Barasa FA, Doll JA, Velazquez EJ. Heart failure in Sub-Saharan Africa. Curr Cardiol Rev. 2013;9(2):157–173. doi:10.2174/1573403X11309020008
  • Mocumbi AO. Lack of focus on cardiovascular disease in sub-Saharan Africa. Cardiovasc Diagn Ther. 2012;2(1):74–77. doi:10.3978/j.issn.2223-3652.2012.01.03
  • Opie LH, Mayosi BM, Sa FCP. Cardiovascular Disease in Sub-Saharan Africa. Circulation. 2005;112(23):3536–3540. doi:10.1161/CIRCULATIONAHA.105.597765
  • Mayosi BM. Contemporary trends in the epidemiology and management of cardiomyopathy and pericarditis in sub-Saharan Africa. Heart. 2007;93(10):1176–1183. doi:10.1136/hrt.2007.127746
  • Onwuchekwa AC, Asekomeh GE. Pattern of heart failure in a Nigerian teaching hospital. Vasc Health Risk Manag. 2009;5:745–750. doi:10.2147/vhrm.s6804
  • Ansa VO, Ekott JU, Bassey EO. Profile and outcome of cardiovascular admissions at the University of Uyo Teaching Hospital, Uyo-a five year review. Niger J Clin Pract. 2008;11(1):22–24.
  • Maro E, Kaushik R. The role of echocardiography in the management of patients with congestive heart failure. “Tanzanian experience” Abstract. Cent Afr J Med. 2009;55(5):35–40. doi:10.4314/cajm.v55i5-8.63638
  • Oli K, Asmera J. Rheumatic heart disease in Ethiopia: could it be more malignant? Ethiop Med J. 2004;42(1):1–8.
  • Gebremedhin A, Shamebo M. Deep venous thrombosis in a University Teaching Hospital, Addis Ababa, Ethiopia. East Afr Med J. 1998;75(7):432–435.
  • Danwang C, Temgoua MN, Agbor VN, Tankeu AT, Noubiap JJ. Epidemiology of venous thromboembolism in Africa: a systematic review. J Thromb Haemost. 2017;15(9):1770–1781. doi:10.1111/jth.13769
  • Goldhaber SZ, Morrison RB. Pulmonary embolism and deep vein thrombosis. Lancet. 2012;379(9829):1835–1846. doi:10.1016/S0140-6736(11)61904-1
  • Amare H, Getachew A. Deep vein thrombosis in a tertiary hospital from Ethiopia. Thromb Res. 2021;198:17–18. doi:10.1016/j.thromres.2020.11.019
  • Mensah GA. Ischaemic heart disease in Africa. Heart. 2008;94(7):836–843. doi:10.1136/hrt.2007.136523
  • Fikreyesus Y, Bahta Y. Myocardial infarction in the Tikur Anbessa Teaching Hospital. A five-year review. Ethiop Med J. 1989;27(2):55–61.
  • Shashu BA, Ayele MA. Original article The pattern of coronary artery diseases as diagnosed by coronary angiography and the outcome of Percutaneous Coronary Intervention (PCI) in Ethiopia. Ethiop J Heal Dev. 2007;28:11–16.
  • Beri B, Fanta K, Bekele F, Bedada W. Management, clinical outcomes, and its predictors among heart failure patients admitted to tertiary care hospitals in Ethiopia: prospective observational study. BMC Cardiovasc Disord. 2023;23(1):1–10. doi:10.1186/s12872-022-03008-7
  • Mayosi BM, Wiysonge CS, Ntsekhe M, et al. Clinical characteristics and initial management of patients with tuberculous pericarditis in the HIV era: the Investigation of the Management of Pericarditis in Africa (IMPI Africa) registry. BMC Infect Dis. 2006;9:1–9.
  • Stewart S, Mocumbi AO, Carrington MJ, Pretorius S, Burton R, Sliwa K. A not-so-rare form of heart failure in urban black Africans: pathways to right heart failure in the Heart of Soweto Study cohort. Eur J Heart Fail. 2011;13(10):1070–1077. doi:10.1093/eurjhf/hfr108
  • Sulaiman K, Panduranga P, Al-zakwani I, et al. Clinical characteristics, management, and outcomes of acute heart failure patients: observations from the Gulf acute heart failure registry (Gulf CARE). Eur J Heart Fail. 2015;17(4):374–384. doi:10.1002/ejhf.245
  • Amoah AGB, Kallen C. Aetiology of heart failure as seen from a national cardiac referral centre in Africa. Cardiology. 2000;93(1–2):11–18. doi:10.1159/000006996
  • Cleland JGF, Swedberg K, Follath F, et al. The EuroHeart Failure survey programme - A survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis. Eur Heart J. 2003;24(5):442–463. doi:10.1016/S0195-668X(02)00823-0
  • Yancy CW, Abraham WT, Albert NM, et al. Quality of Care of and Outcomes for African Americans Hospitalized With Heart Failure. Findings From the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) Registry. J Am Coll Cardiol. 2008;51(17):1675–1684. doi:10.1016/j.jacc.2008.01.028
  • Yuyun MF, Sliwa K, Kengne AP, Mocumbi AO, Bukhman G. Cardiovascular diseases in sub-saharan Africa compared to high-income countries: an epidemiological perspective. Glob Heart. 2020;15(1):1–18. doi:10.5334/gh.403
  • Paolo F, Michelle C, Miller A. Cardiovascular disease and hypertension in sub-Saharan Africa: burden, risk and interventions. Intern Emerg Med. 2016;11(3):299–305. doi:10.1007/s11739-016-1423-9
  • Adem A, Demis TFY, Feleke Y. Trend of diabetic admissions in Tikur Anbessa and St. Paul’s University Teaching Hospitals from January 2005-December 2009, Addis Ababa, Ethiopia. Ethiop Med J. 2011;49(3):231–238.
  • Shiferaw F, Letebo M, Misganaw A, et al. Non-communicable Diseases in Ethiopia: disease burden, gaps in health care delivery and strategic directions. Ethiop J Heal Dev. 2018;32(3):1–12.
  • Nalubwama H, Ndagire E, Sarnacki R, et al. Community perspectives on primary prevention of rheumatic heart disease in Uganda. Glob Heart. 2022;17(1):5. doi:10.5334/gh.1094
  • Hailu A, Tsega T, Gebregziabher T, et al. Community awareness of sore throat and rheumatic heart disease in Northern Ethiopia. Sudan Hear J. 2020;7(3):1–25.
  • Sanyahumbi A, Ali S, Benjamin IJ, et al. Penicillin reactions in patients with severe rheumatic heart disease: a presidential advisory from the American Heart Association. J Am Heart Assoc. 2022;11(5):1–9. doi:10.1161/JAHA.121.024517
  • Wyber R, Johnson TD, Patel B. Supply of benzathine penicillin G: the 20-year experience in Australia. Aust N Z J Public Health. 2015;39(6):506–508. doi:10.1111/1753-6405.12415
  • Minja NM, Nakagaayi D, Aliku T, et al. Cardiovascular diseases in Africa in the twenty-first century: gaps and priorities going forward. Front Cardiovasc Med. 2022;9:1–20. doi:10.3389/fcvm.2022.1008335
  • Ataklte F, Erqou S, Kaptoge S, Taye B, Echouffo-Tcheugui JB, Kengne AP. Burden of undiagnosed hypertension in sub-saharan Africa: a systematic review and meta-analysis. Hypertension. 2015;65(2):291–298. doi:10.1161/HYPERTENSIONAHA.114.04394