Age estimation of skeletal remains: principal methods

References

• Cunha E, Baccino E, Martrille L, et al. The problem of aging human remains and living individuals: a review. Forensic Sci Int. 2009;193(1–3):1–13.
   PubMed Web of Science ®Google Scholar
• Mays S. The Archaeology of Human Bones. London: Routledge; 1998.
   Google Scholar
• Buikstra JE, Ubelaker DH. Standards for Data Collection from Human Skeletal Remains. Arkansas Archaeological Survey Research Series 44. Detroit: Wayne State University Press; 1984.
   Google Scholar
• Ubelaker DH. Human Skeletal Remains: Excavation, Analysis, Interpretation. Chicago: Aldine; 1978.
   Google Scholar
• Krogman WM, Iscan MY. The Human Skeleton in Forensic Medicine. Springfield: Charles C Thomas; 1986.
   Google Scholar
• Stewart TD. Essentials of Forensic Anthropology, Especially as Developed in the United States. Springfield: Charles C Thomas; 1979.
   Google Scholar
• Ferembach D, Schwidetzky I, Stoukal M. Recommendations for age and sex diagnoses of skeletons, “Workshop of European anthropologists”. J Hum Evol. 1980;9:517–549.
   Web of Science ®Google Scholar
• Hoffmann JM. Age estimations from diaphyseal lengths: two months to twelve years. J Forensic Sci. 1979;24(2):461–469.
   Web of Science ®Google Scholar
• Scheuer L, Black S. Developmental Juvenile Osteology. New York: Imprint Academic; 2000.
   Google Scholar
• Todd TW, Lyon DW. Cranial suture closure, its progress and age relationship. I. Adult males of white stock. Am J Phys Anthropol. 1924;7(3):325–384.
   Google Scholar
• Perizonius WRK. Closing and Non-closing Sutures in 256 Crania of Known Age and Sex from Amsterdam (ad 1883–1909). J Hum Evol. 1984;13(2):201–216.
   Web of Science ®Google Scholar
• Meindl RS, Lovejoy CO. Ectocranial suture closure: a revised method for the determination of skeletal age at death based on the lateral-anterior sutures. Am J Phys Anthropol. 1985;68(1):57–66.
   PubMed Web of Science ®Google Scholar
• Key CA, Aiello LC, Molleson T. Cranial suture closure and its implications for age estimation. Int J Osteoarch. 1994;4(3):193–207.
   Google Scholar
• Hauser G, Manzi G, Vienna A, De Stefano GF. Size and shape of human cranial sutures A new scoring method. Am J Anat. 1991;190(3):231–244.
   Google Scholar
• Acsadi G, Nemeskeri J. History of Human Lifespan and Mortality. Budapest: Academiai; 1970.
   Google Scholar
• Galera V, Ubelaker DH, Hayek LA. Comparison of macroscopic cranial methods of age estimation applied to skeletons from the Terry Collection. J Forensic Sci. 1998;43(5):933–939.
   Web of Science ®Google Scholar
• Dorandeu A, Coulibaly B, Piercecchi-Marti MD, et al. Age-at-death estimation based on the study of frontosphenoidal sutures. Forensic Sci Int. 2008;177(1):47–51.
   Web of Science ®Google Scholar
• Dorandeu A, Lorin de la Grandmaison G, Coulibaly B, et al. Value of histologicval study in the fronto-sphenoidal suture for the age estimation at the time of death. Forensic Sci Int. 2009;191(1–3):64–69.
   Web of Science ®Google Scholar
• Alesbury HS, Ubelaker DH, Berstein R. Utility of the frontonasal suture for estimating age at death in human skeletal remains. J Forensic Sci. 2013;58(1):104–108.
   Web of Science ®Google Scholar
• Wehrbein H, Yildizhan F. The mid-palatal suture in young adults. A radiological-histological investigation. Eur J Orthod. 2001;23:105–114.
   Web of Science ®Google Scholar
• Sejrsen B, Kjaer I, Jakobsen J. The human incisal suture and premaxillary area studied on archaeologic material. Acta Odontol Scand. 1993;51(3):143–151.
   PubMed Web of Science ®Google Scholar
• Todd TW. Age changes in the pubic bone. I. The male white pubis. Am J Phys Anthropol. 1920;3:285–334.
   Google Scholar
• Katz D, Suchey JM. Age determination of the male os pubis. Am J Phys Anthropol. 1986;69(4):427–435.
   Web of Science ®Google Scholar
• Suchey JM, Wisely DV, Katz D. Instructional material accompanying models of the Suchey–Brooks system. Bellevue, CO: France Casting; 1988.
   Google Scholar
• Lovejoy CO, Meindl RS, Pryzbeck TR, Mensforth RP. Chronological metamorphosis of the auricular surface of the ilium: A new method for the determination of adult skeletal age at death. Am J Phys Anthropol. 1985;68(1):15–28.
   PubMed Web of Science ®Google Scholar
• Buckberry JL, Chamberlain AT. Age estimation from the auricular surface of the ilium: a revised method. Am J Phys Anthropol. 2002;119(3):231–239.
   PubMed Web of Science ®Google Scholar
• Iscan MY, Loth SR, Wright RK. Metamorphosis at the sternal rib end: a new method to estimate age at death in white males. Am J Phys Anthropol. 1984;65(2):147–156.
   PubMed Web of Science ®Google Scholar
• Ican MY, Loth SR. Wright TK. Casts of age phases from the sternal end of the rib for white males and females. Bellevue, CO: France Casting; 1993.
   Google Scholar
• Sokolove J, Lepus CM. Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations. Ther Adv Musculoskelet Dis. 2013;5(2):77–94.
   PubMedGoogle Scholar
• Milner GR, Boldsen JL. Transition analysis: a validation study with known-age modern American skeletons. Am J Phys Anthropol. 2012;148(1):98–110.
   Web of Science ®Google Scholar
• Lynnerup N, Thomsen I, Frøhlich B. A non-invasive method for age at death determination. Med Sci Law. 1990;30(4):317–320.
   Google Scholar
• Dedouit F, Bindel S, Gainza D, et al. Application of the Iscan method to two- and three-dimensional imaging of the sternal end of the right fourth rib. J Forensic Sci. 2008;53(2):288–295.
   Web of Science ®Google Scholar
• Grabherr S, Cooper C, Ulrich-Bochsler S, et al. Estimation of sex and age of “virtual skeletons” – a feasibility study. Eur Radiol. 2009;19:419–429.
   PubMed Web of Science ®Google Scholar
• Telmon N, Gaston A, Chemla P, Blanc A, Joffre F, Rouge D. Application of the Suchey-Brooks method to three-dimensional imaging of the pubic symphysis. J Forensic Sci. 2005;50(3):507–512.
   PubMed Web of Science ®Google Scholar
• Ferrant O, Rouge-Maillart C, Guittet L, et al. Age at death estimation of adult males using coxal bone and CT scan: a preliminary study. Forensic Sci Int. 2009;186(1–3):14–21.
   Web of Science ®Google Scholar
• Barrier P, Dedouit F, Braga J, et al. Age at death estimation using multislice computed tomography reconstructions of the posterior pelvis. J Forensic Sci. 2009;54(4):773–778.
   Web of Science ®Google Scholar
• Pasquier E, De Saint Martin Pernot L, Burdin V, et al. Determination of age at death: assessment of an algorithm of age prediction using numerical three-dimensional CT data from pubic bones. Am J Phys Anthropol. 1999;108(3):261–268.
   Web of Science ®Google Scholar
• Wade A, Nelson A, Garvin G, Holdsworth DW. Preliminary radiological assessment of age-related change in the trabecular structure of the human os pubis. J Forensic Sci. 2011;56(2):312–319.
   Web of Science ®Google Scholar
• Biwasaka H, Sato K, Aoki Y, et al. Three dimensional surface analyses of pubic symphyseal faces of contemporary Japanese reconstructed with 3D digitized scanner. Leg Med (Tokyo). 2013;15(5):264–268.
   Web of Science ®Google Scholar
• Boldsen JL, Milner GR, Konigsberg LW, Wood JW. Transition analysis: a new method for estimating age from skeletons. In: Hoppa R, Vaupel J, editors. Paleodemography: Age Distributions from Skeletal Samples. Cambridge, UK: Cambridge University Press; 2002:73–106.
   Google Scholar
• Kerley ER. The microscopic determination of age in human bone. Am J Phys Anthropol. 1965;23(2):149–163.
   Web of Science ®Google Scholar
• Ahlqvist J, Damsten O. A modification of Kerley’s method for the microscopic determination of age in human bone. J Forensic Sci. 1969;14(2):205–212.
   Google Scholar
• Bouvier M, Ubelaker DH. A comparison of two methods for the microscopic determiantion of age at death. Am J Phys Anthropol. 1977;46(3):391–394.
   PubMed Web of Science ®Google Scholar
• Kerley ER, Ubelaker DH. Revisions in the microscopic method of estimating age at death in human cortical bone. Am J Phys Anthropol. 1978;49(4):545–546.
   Web of Science ®Google Scholar
• Ericksen MF. Histologic estimation of age at death using the anterior cortex of the femur. Am J Phys Anthropol. 1991;84(2):171–179.
   Web of Science ®Google Scholar
• Lazenby RA. Inherrent deficiencies in cortical bone microstructural age estimation techniques. Ossa. 1984;9–11:95–103.
   Google Scholar
• Martin DL, Goodman AH, Armelagos GJ, Pfeiffer S. On the use of microstructural bone for age identification. Curr Anthropol. 1981;22(4):437–438.
   Web of Science ®Google Scholar
• Pfeiffer S, Lazenby R, Chiang J. Brief Communication: Cortical remodelling data are affected by sampling location. Am J Phys Anthropol. 1995;96:89–92.
   Web of Science ®Google Scholar
• Helfman PM, Bada JL. Aspartic acid racemization in tooth enamel from living humans. Proc Natl Acad Sci U S A. 1975;72(8):2891–2894.
   Web of Science ®Google Scholar
• Helfman PM, Bada JL. Aspartic acid racemization in dentine as a measure of ageing. Nature. 1976;262(5566):279–281.
   Web of Science ®Google Scholar
• Ohtani S, Yamamoto K. Age estimation using the racemization of amino acid in human dentin. J Forensic Sci. 1991;36(3):792–800.
   Web of Science ®Google Scholar
• Mörnstad H, Pfeiffer H, Teivens A. Estimation of dental age using HPLC-technique to determine the degree of aspartic acid racemization. J Forensic Sci. 1994;39(6):1425–1431.
   PubMed Web of Science ®Google Scholar
• Ritz S, Schütz WH. Aspartic acid racemization in intervertebral discs as an aid to postmortem estimation of age at death. J Forensic Sci. 1993;38:633–640.
   Web of Science ®Google Scholar
• Ritz S, Turzynski A, Schütz HW. Estimation of age at death based on aspartic acid racemization in noncollagenous bone protein. Forensic Sci Int. 1994;69(2):149–159.
   Web of Science ®Google Scholar
• Masters PM, Bada JL, Zigler JS Jr. Aspartic acid racemization in the human lens during ageing and in cataract formation. Nature. 1977;268(5615):71–73.
   Web of Science ®Google Scholar
• Zapico S, Ubelaker DH. Applications of physiological bases of ageing to forensic sciences. Estimation of age-at-death. Ageing Res Rev. 2013;12(2):605–617.
   Web of Science ®Google Scholar
• Eyre DR, Dickson IR, Van Ness K. Collagen cross-linking in human bone and articular cartilage. Age-related changes in the content of mature hydroxypyridinium residues. Biochem J. 1988;252(2):495–500.
   PubMed Web of Science ®Google Scholar
• Martin de las Heras S, Valenzuela A, Villanueva E. Deoxypyridinoline crosslinks in human dentin and estimation of age. Int J Legal Med. 1999;112(4):222–226.
   Web of Science ®Google Scholar
• Bank RA, Bayliss MT, Lafeber FP, Maroudas A, Tekoppele JM. Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage. Biochem J. 1998;330(Pt 1):345–351.
   Google Scholar
• Solheim T. A new method for dental age estimation in adults. Forensic Sci Int. 1993;59(2):137–147.
   PubMed Web of Science ®Google Scholar
• Martin de las Heras S, Valenzuela A, Bellini R, Salas C, Rubino M, Garcia JA. Objective measurement of dental color for age estimation by spectroradiometry. Forensic Sci Int. 2003;132:57–62.
   Web of Science ®Google Scholar
• Painter TJ. Lindow man, tollund man and other peat-bog bodies: The preservative and antimicrobial action of Sphagnan, a reactive glycuronogylcan with tanning and sequestering properties. Carbohydr Polym. 1991;15(2):123–142.
   Web of Science ®Google Scholar
• Butler MG, Tilburt J, DeVries A, et al. Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages. Cancer Genet Cytogenet. 1998;105(2):138–144.
   Google Scholar
• Tsuji A, Ishiko A, Takasaki T, Ikeda N. Estimating age of humans based on telomere shortening. Forensic Sci Int. 2002;126:197–199.
   PubMed Web of Science ®Google Scholar
• Takasaki T, Tsuji A, Ikeda N, Ohishi M, 2003. Age estimation in dental pulp DNA based on human telomere shortening. Int J Leg Med. 2003;117(4):232–234.
   PubMed Web of Science ®Google Scholar
• Ren F, Li C, Xi H, Wen Y, Huang K. Estimation of human age according to telomere shortening in peripheral blood leukocytes of Tibetan. Am J Forensic Med Pathol. 2009;30(3):252–255.
   Web of Science ®Google Scholar
• Masters PM. Age at death determinations for autopsied remains based on aspartic acid racemization in tooth dentin: importance of postmortem conditions. Forensic Sci Int. 1986;32(3):179–184.
   Web of Science ®Google Scholar
• Carolan VA, Gardner ML, Lucy D, Pollard AM. Some considerations regarding the use of amino acid racemization in human dentine as an indicator of age at death. J Forensic Sci. 1997;42(1):10–16.
   Web of Science ®Google Scholar
• Spalding KL, Buchholz BA, Bergman LE, Druid H, Frisen J. Age written in teeth by nuclear tests. Nature. 2005;437(7057):333–334.
   Web of Science ®Google Scholar
• De Vries H. Atomic bomb effect: variation of radiocarbon in plants, shells, and snails in the past 4 years. Science. 1985;128(33):250–251.
   Google Scholar
• Levin I, Kromer B. The tropospheric 14CO2 level in mid-latitudes of the Northern Hemisphere (1959–2003). Radiocarbon. 2004;46(3):1261–1272.
   Web of Science ®Google Scholar
• Goodsite ME, Rom W, Heinemeier J, et al. High-resolution AMS (super 14) C dating of post-bomb peat archives of atmospheric pollutants. Radiocarbon. 2001;43(2B):495–515.
   Web of Science ®Google Scholar
• Kueppers L, Southon J, Baer P, Harte J. Dead wood biomass and turnover time, measured by radiocarbon, along a subalpine elevation gradient. Oecologia. 2004;141(4):641–651.
   PubMed Web of Science ®Google Scholar
• Bhardwaj RD, Curtis MA, Spalding KL, et al. Neocortical neurogenesis in humans is restricted to development. Proc Natl Acad Sci U S A. 2006;103(33):12564–12568.
   Web of Science ®Google Scholar
• Lynnerup N, Kjeldsen H, Heegaard S, Jacobsen C, Heinemeier J. Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life. PLoS One. 2008;3(1):e1529.
   Web of Science ®Google Scholar
• Hedges RE, Clement JG, Thomas CD, O’Connell TC. Collagen turnover in the adult femoral mid-shaft: modeled from anthropogenic radiocarbon tracer measurements. Am J Phys Anthropol. 2007;133(2):808–816.
   PubMed Web of Science ®Google Scholar
• Jørkov ML, Heinemeier J, Lynnerup N. The petrous bone – a new sampling site for identifying early dietary patterns in stable isotopic studies. Am J Phys Anthropol. 2009;138(2):199–209.
   Web of Science ®Google Scholar
• Lovejoy CO, Meindl RS, Mensforth RP, Barton TJ. Multifactorial determination of skeletal age at death: a method and blind tests of its accuracy. Am J Phys Anthropol. 1985;68(1):1–14.
   Web of Science ®Google Scholar
• Milner GR, Wood JM, Boldsen J. Paleodemography. In: Katzenberg MA, Saunders SR, editors. Biological Anthropology of the Human Skeleton. New York: Wiley; 2000. pp. 467–498.
   Google Scholar
• Konigsberg LW, Herrmann NP, Wescott DJ, Kimmerle EH. Estimation and evidence in forensic anthropology: age-at-death. J Forensic Sci. 2008;53(3):541–557.
   PubMed Web of Science ®Google Scholar