Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations

References

• StevensLCDevelopment of resistance to teratocarcinogenesis by primordial germ cells in miceJ Natl Cancer Inst19663768598676005945
   PubMedGoogle Scholar
• AndrewsPWTeratocarcinomas and human embryology: pluripotent human EC cell lines. Review articleApmis199810611581679524574
   PubMed Web of Science ®Google Scholar
• StevensLCOrigin of testicular teratomas from primordial germ cells in miceJ Natl Cancer Inst19673845495526025005
   PubMedGoogle Scholar
• YuJThomsonJAPluripotent stem cell linesGenes Dev200822151987199718676805
   PubMed Web of Science ®Google Scholar
• EguizabalCShovlinTCDurcova-HillsGSuraniAMcLarenAGeneration of primordial germ cells from pluripotent stem cellsDifferentiation2009782–311612319683852
   PubMed Web of Science ®Google Scholar
• YuZJiPCaoJDazl promotes germ cell differentiation from embryonic stem cellsJ Mol Cell Biol2009129310319783541
   PubMed Web of Science ®Google Scholar
• HastonKMTungJYReijo PeraRADazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitroPLoS One200945e565419468308
   PubMed Web of Science ®Google Scholar
• GeijsenNHoroschakMKimKGribnauJEgganKDaleyGQDerivation of embryonic germ cells and male gametes from embryonic stem cellsNature2004427697014815414668819
   PubMed Web of Science ®Google Scholar
• HubnerKFuhrmannGChristensonLKDerivation of oocytes from mouse embryonic stem cellsScience200330056231251125612730498
   PubMed Web of Science ®Google Scholar
• NayerniaKNolteJMichelmannHWIn vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring miceDev Cell200611112513216824959
   PubMed Web of Science ®Google Scholar
• ToyookaYTsunekawaNAkasuRNoceTEmbryonic stem cells can form germ cells in vitroProc Natl Acad Sci U S A200310020114571146214504407
   PubMed Web of Science ®Google Scholar
• Lacham-KaplanOChyHTrounsonATesticular cell conditioned medium supports differentiation of embryonic stem cells into ovarian structures containing oocytesStem Cells200624226627316109761
   PubMed Web of Science ®Google Scholar
• KerkisAFonsecaSASerafimRCIn vitro differentiation of male mouse embryonic stem cells into both presumptive sperm cells and oocytesCloning Stem Cells20079453554818154514
   PubMedGoogle Scholar
• ClarkATBodnarMSFoxMSpontaneous differentiation of germ cells from human embryonic stem cells In vitroHum Mol Genet200413772773914962983
   PubMed Web of Science ®Google Scholar
• AflatoonianBMooreHHuman primordial germ cells and embryonic germ cells, and their use in cell therapyCurr Opin Biotechnol200516553053516154336
   PubMed Web of Science ®Google Scholar
• KeeKGonsalvesJMClarkATPeraRABone morphogenetic proteins induce germ cell differentiation from human embryonic stem cellsStem Cells Dev200615683183717253946
   PubMed Web of Science ®Google Scholar
• TilgnerKAtkinsonSPGolebiewskaAStojkovicMLakoMArmstrongLIsolation of primordial germ cells from differentiating human embryonic stem cellsStem Cells200826123075308518802037
   PubMed Web of Science ®Google Scholar
• ParkTSGalicZConwayAEDerivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cellsStem Cells200927478379519350678
   PubMed Web of Science ®Google Scholar
• WestFDMachacekDWBoydNLPandiyanKRobbinsKRSticeSLEnrichment and differentiation of human germ-like cells mediated by feeder cells and basic fibroblast growth factor signalingStem Cells200826112768277618719225
   PubMed Web of Science ®Google Scholar
• BucayNYebraMCirulliVA novel approach for the derivation of putative primordial germ cells and sertoli cells from human embryonic stem cellsStem Cells2009271687718845765
   PubMed Web of Science ®Google Scholar
• ZhaoXYLiWLvZiPS cells produce viable mice through tetraploid complementationNature20094617260869019672241
   PubMed Web of Science ®Google Scholar
• NagyAGoczaEDiazEMEmbryonic stem cells alone are able to support fetal development in the mouseDevelopment199011038158212088722
   PubMed Web of Science ®Google Scholar
• ThomsonJAEmbryonic stem cell lines derived from human blastocysts [comment][erratum appears in Science 1998 4;282(5395):1827]Science19982825391114511479804556
   PubMed Web of Science ®Google Scholar
• ShamblottMJAxelmanJWangSDerivation of pluripotent stem cells from cultured human primordial germ cellsProc Natl Acad Sci U S A1998952313726137319811868
   PubMed Web of Science ®Google Scholar
• EvansMJKaufmanMHEstablishment in culture of pluripotential cells from mouse embryosNature198129258191541567242681
   PubMed Web of Science ®Google Scholar
• MartinGRIsolation of a pluripotent cell line from early mouse embryos cultured in media conditioned by teratocarcinoma stem cellsProc Natl Acad Sci U S A198178763476386950406
   PubMed Web of Science ®Google Scholar
• SmithAGEmbryo-derived stem cells: of mice and menAnnu Rev Cell Dev Biol20011743546211687496
   PubMed Web of Science ®Google Scholar
• AmitMItskovitz-EldorJDerivation and maintenance of human embryonic stem cellsTurksenTMethods in Molecular Biology, Volume 331: Human Embryonic Stem Cell ProtocolsNew YorkHumana Press20064353
   Google Scholar
• SullivanSCowanCAEgganKHuman Embryonic Stem Cells: The Practical HandbookWest SussexJohn Wiley and Sons, Ltd2007
   Google Scholar
• KlimanskayaILanzaRMethods in Enzymology, Volume 418: Embryonic Stem CellsSan DiegoAcademic Press2006
   Google Scholar
• LerouPHYabuuchiAHuoHDerivation, growth and applications of human embryonic stem cells from poor-quality in vitro fertilization embryosReproduction2004128325926715333777
   PubMed Web of Science ®Google Scholar
• LerouPHYabuuchiAHuoHDerivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryosReprod Biomed Online200835923933
   Google Scholar
• BavisterBOxygen concentration and preimplantation developmentReprod Biomed Online20049548448615588462
   PubMed Web of Science ®Google Scholar
• EzashiTDasPRobertsRMLow O2 tensions and the prevention of differentiation of hES cellsProc Natl Acad Sci U S A2005102134783478815772165
   PubMed Web of Science ®Google Scholar
• ForsythNRMusioAVezzoniPSimpsonAHNobleBSMcWhirJPhysiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalitiesCloning Stem Cells200681162316571074
   PubMedGoogle Scholar
• YoshidaYTakahashiKOkitaKIchisakaTYamanakaSHypoxia enhances the generation of induced pluripotent stem cellsCell Stem Cell20095323724119716359
   PubMed Web of Science ®Google Scholar
• LerouPHYabuuchiAHuoHDerivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryosNat Protoc20083592393318451800
   PubMed Web of Science ®Google Scholar
• CowanCAVSvetlakovAVPolstianoyAMDerivation of a novel human embryonic stem-cell line under serum-free and feeder-free conditionsDokl Biol Sci20043501313531356
   Google Scholar
• LudwigTEBergendahlVLevensteinMEYuJProbascoMDThomsonJAFeeder-independent culture of human embryonic stem cellsNat Methods20063863764616862139
   PubMed Web of Science ®Google Scholar
• LudwigTELevensteinMEJonesJMDerivation of human embryonic stem cells in defined conditionsNat Biotechnol200624218518716388305
   PubMed Web of Science ®Google Scholar
• KimCAmanoTParkJCarterMGTianXYangXImprovement of embryonic stem cell line derivation efficiency with novel medium, glucose concentration, and epigenetic modificationsCloning Stem Cells20091118910019226216
   PubMedGoogle Scholar
• Tsuji-TakayamaKInoueTIjiriYDemethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cellsBiochem Biophys Res Commun20043231869015351705
   PubMed Web of Science ®Google Scholar
• LeeJHHartSRSkalnikDGHistone deacetylase activity is required for embryonic stem cell differentiationGenesis2004381323814755802
   PubMed Web of Science ®Google Scholar
• FengBNgJHHengJCNgHHMolecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cellsCell Stem Cell20094430131219341620
   PubMed Web of Science ®Google Scholar
• LeeHParkJForgetBGGainesPInduced pluripotent stem cells in regenerative medicine: an argument for continued research on human embryonic stem cellsRegen Med20094575976919761400
   PubMed Web of Science ®Google Scholar
• AmabileGMeissnerAInduced pluripotent stem cells: current progress and potential for regenerative medicineTrends Mol Med2009152596819162546
   PubMed Web of Science ®Google Scholar
• KiuruMBoyerJLO’ConnorTPCrystalRGGenetic control of wayward pluripotent stem cells and their progeny after transplantationCell Stem Cell20094428930019341619
   PubMed Web of Science ®Google Scholar
• FengBJiangJKrausPReprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor EsrrbNat Cell Biol200911219720319136965
   PubMed Web of Science ®Google Scholar
• HuangfuDOsafuneKMaehrRInduction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2Nat Biotechnol200826111269127518849973
   PubMed Web of Science ®Google Scholar
• MaliPYeZHommondHHImproved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblastsStem Cells20082681998200518511599
   PubMed Web of Science ®Google Scholar
• StadtfeldMNagayaMUtikalJWeirGHochedlingerKInduced pluripotent stem cells generated without viral integrationScience2008322590394594918818365
   PubMed Web of Science ®Google Scholar
• OkitaKNakagawaMHyenjongHIchisakaTYamanakaSGeneration of mouse induced pluripotent stem cells without viral vectorsScience2008322590394995318845712
   PubMed Web of Science ®Google Scholar
• KajiKNorrbyKPacaAMileikovskyMMohseniPWoltjenKVirus-free induction of pluripotency and subsequent excision of reprogramming factorsNature2009458723977177519252477
   PubMed Web of Science ®Google Scholar
• WoltjenKMichaelIPMohseniPpiggyBac transposition reprograms fibroblasts to induced pluripotent stem cellsNature2009458723976677019252478
   PubMed Web of Science ®Google Scholar
• KimDKimCHMoonJIGeneration of human induced pluripotent stem cells by direct delivery of reprogramming proteinsCell Stem Cell20094647247619481515
   PubMed Web of Science ®Google Scholar
• MikkelsenTSHannaJZhangXDissecting direct reprogramming through integrative genomic analysisNature20084547200495518509334
   PubMed Web of Science ®Google Scholar
• ShiYDoJTDespontsCHahmHSScholerHRDingSA combined chemical and genetic approach for the generation of induced pluripotent stem cellsCell Stem Cell20082652552818522845
   PubMed Web of Science ®Google Scholar
• MarsonAForemanRChevalierBWnt signaling promotes reprogramming of somatic cells to pluripotencyCell Stem Cell20083213213518682236
   PubMed Web of Science ®Google Scholar
• SilvaJBarrandonONicholsJKawaguchiJTheunissenTWSmithAPromotion of reprogramming to ground state pluripotency by signal inhibitionPLoS Biol2008610e25318942890
   PubMed Web of Science ®Google Scholar
• LiWWeiWZhuSGeneration of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitorsCell Stem Cell200941161919097958
   PubMed Web of Science ®Google Scholar
• PaliiSSVan EmburghBOSankpalUTBrownKDRobertsonKDDNA methylation inhibitor 5-Aza-2’-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3BMol Cell Biol200828275277117991895
   PubMed Web of Science ®Google Scholar
• BrockesJPKumarAPlasticity and reprogramming of differentiated cells in amphibian regenerationNat Rev Mol Cell Biol20023856657412154368
   PubMed Web of Science ®Google Scholar
• ByrneJANguyenHNReijo PeraRAEnhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblastsPLoS One200949e711819774082
   PubMed Web of Science ®Google Scholar
• YamanakaSElite and stochastic models for induced pluripotent stem cell generationNature20094607251495219571877
   PubMed Web of Science ®Google Scholar
• HongHTakahashiKIchisakaTSuppression of induced pluripotent stem cell generation by the p53-p21 pathwayNature200946072591132113519668191
   PubMed Web of Science ®Google Scholar
• BanitoARashidSTAcostaJCSenescence impairs successful reprogramming to pluripotent stem cellsGenes Dev200923182134213919696146
   PubMed Web of Science ®Google Scholar
• EguchiGOkadaTSDifferentiation of lens tissue from the progeny of chick retinal pigment cells cultured in vitro: a demonstration of a switch of cell types in clonal cell cultureProc Natl Acad Sci U S A1973705149514994576021
   PubMed Web of Science ®Google Scholar
• XieHYeMFengRGrafTStepwise reprogramming of B cells into macrophagesCell2004117566367615163413
   PubMed Web of Science ®Google Scholar
• ZhouQBrownJKanarekARajagopalJMeltonDAIn vivo reprogramming of adult pancreatic exocrine cells to beta-cellsNature2008455721362763218754011
   PubMed Web of Science ®Google Scholar
• BakerTGFranchiLLThe fine structure of oogonia and oocytes in human ovariesJ Cell Sci1967222132244933750
   PubMed Web of Science ®Google Scholar
• SunELGondosBSquash preparation studies of germ cells in human fetal testesJ Androl19849553343386542097
   PubMedGoogle Scholar
• MakabeSNaguroTMottaPMA new approach to the study of ovarian follicles by scanning electron microscopy and ODO macerationArch Histol Cytol199255Suppl1831901283951
   PubMedGoogle Scholar
• HeynRMakabeSMottaPMUltrastructural dynamics of human testicular cords from 6 to 16 weeks of embryonic development. Study by transmission and high resolution scanning electron microscopyItal J Anat Embryol19981034 Suppl 1172911315948
   PubMedGoogle Scholar
• BendsenEByskovAGLaursenSBLarsenHPAndersenCYWestergaardLGNumber of germ cells and somatic cells in human fetal testes during the first weeks after sex differentiationHum Reprod2003181131812525434
   PubMed Web of Science ®Google Scholar
• FrancavillaSCordeschiGProperziGConcordiaNCappaFPozziVUltrastructure of fetal human gonad before sexual differentiation and during early testicular and ovarian developmentJ Submicrosc Cytol Pathol19902233894002390761
   PubMedGoogle Scholar
• WitschiEEmbryology of the OvaryGradyHGSmithDEThe OvaryBaltimoreWilliams and Wilkins1963110
   Google Scholar
• WartenbergHDevelopment of the early human ovary and role of the mesonephros in the differentiation of the cortexAnat Embryol (Berl)198216522532807158813
   PubMedGoogle Scholar
• GondosBHobelCJUltrastructure of germ cell development in the human fetal testisZ Zellforsch Mikrosk Anat197111911204327535
   PubMedGoogle Scholar
• LaboskyPAHoganBLMouse primordial germ cells: isolation and in vitro cultureMethods Mol Biol200846118719919030797
   PubMedGoogle Scholar
• DolciSPesceMDe FeliciMCombined action of stem cell factor, leukemia inhibitory factor, and cAMP on in vitro proliferation of mouse primordial germ cellsMol Reprod Dev19933521341397686377
   PubMed Web of Science ®Google Scholar
• HuaJYuHLiuSDerivation and characterization of human embryonic germ cells: serum-free culture and differentiation potentialReprod Biomed Online200919223824919712561
   PubMed Web of Science ®Google Scholar
• GodinIWylieCCTGF beta 1 inhibits proliferation and has a chemotropic effect on mouse primordial germ cells in cultureDevelopment19911134145114571811953
   PubMed Web of Science ®Google Scholar
• MatsuiYToksozDNishikawaSEffect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in cultureNature199135363467507521719421
   PubMed Web of Science ®Google Scholar
• DolciSWilliamsDEErnstMKRequirement for mast cell growth factor for primordial germ cell survival in cultureNature199135263388098111715518
   PubMed Web of Science ®Google Scholar
• LaboskyPABarlowDPHoganBLEmbryonic germ cell lines and their derivation from mouse primordial germ cellsCiba Found Symp19941821571687835148
   PubMedGoogle Scholar
• NiwaHBurdonTChambersISmithASelf-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Genes Dev19981213204820609649508
   PubMed Web of Science ®Google Scholar
• ShamblottMJKerrCLAxelmanJDerivation and Differentiation of Human Embryonic Germ CellsLanzaRHoganBMeltonDPedersenRThomsonJWestMHandbook of Stem Cells1New YorkElsevier Academic Press2004459469
   Google Scholar
• De FeliciMDolciSPesceMProliferation of mouse primordial germ cells in vitro: a key role for cAMPDev Biol199315712772808387035
   PubMed Web of Science ®Google Scholar
• ResnickJLBixlerLSChengLDonovanPJLong-term proliferation of mouse primordial germ cells in cultureNature199235963955505511383830
   PubMed Web of Science ®Google Scholar
• MatsuiYZseboKHoganBLDerivation of pluripotential embryonic stem cells from murine primordial germ cells in cultureCell19927058418471381289
   PubMed Web of Science ®Google Scholar
• GuanKNayerniaKMaierLSPluripotency of spermatogonial stem cells from adult mouse testisNature200644070881199120316565704
   PubMed Web of Science ®Google Scholar
• IzadyarFPauFMarhJGeneration of multipotent cell lines from a distinct population of male germ line stem cellsReproduction2008135677178418502893
   PubMed Web of Science ®Google Scholar
• Kanatsu-ShinoharaMInoueKLeeJGeneration of pluripotent stem cells from neonatal mouse testisCell200411971001101215620358
   PubMed Web of Science ®Google Scholar
• ConradSRenningerMHennenlotterJGeneration of pluripotent stem cells from adult human testisNature2008456722034434918849962
   PubMed Web of Science ®Google Scholar
• KossackNMenesesJShefiSIsolation and characterization of pluripotent human spermatogonial stem cell-derived cellsStem Cells200927113814918927477
   PubMed Web of Science ®Google Scholar
• KoKTapiaNWuGInduction of pluripotency in adult unipotent germline stem cellsCell Stem Cell200951879619570517
   PubMed Web of Science ®Google Scholar
• KossackNMenesesJShefiSIsolation and characterization of pluripotent human spermatogonial stem cell-derived cellsStem Cells200927113814918927477
   PubMed Web of Science ®Google Scholar
• DymMHeZJiangJPantDKokkinakiMSpermatogonial stem cells: unlimited potentialReprod Fertil Dev2009211152119152741
   PubMed Web of Science ®Google Scholar
• OatleyJMBrinsterRLSpermatogonial stem cellsMethods Enzymol200641925928217141059
   PubMed Web of Science ®Google Scholar
• Kanatsu-ShinoharaMTakehashiMShinoharaTBrief history, pitfalls, and prospects of mammalian spermatogonial stem cell researchCold Spring Harb Symp Quant Biol200873l 723
   Google Scholar
• RougierNWerbZMinireview: Parthenogenesis in mammalsMol Reprod Dev200159446847411468784
   PubMed Web of Science ®Google Scholar
• RevazovaESTurovetsNAKochetkovaODPatient-specific stem cell lines derived from human parthenogenetic blastocystsCloning Stem Cells20079343244917594198
   PubMedGoogle Scholar
• CibelliJBCunniffKVranaKEEmbryonic stem cells from parthe-notesMethods Enzymol200641811713517141033
   PubMed Web of Science ®Google Scholar
• SuraniMABartonSCNorrisMLDevelopment of reconstituted mouse eggs suggests imprinting of the genome during gametogenesisNature198430859595485506709062
   PubMed Web of Science ®Google Scholar
• McGrathJSolterDInability of mouse blastomere nuclei transferred to enucleated zygotes to support development in vitroScience19842264680131713196542249
   PubMed Web of Science ®Google Scholar
• KonoTObataYWuQBirth of parthenogenetic mice that can develop to adulthoodNature2004428698586086415103378
   PubMed Web of Science ®Google Scholar
• WuQKumagaiTKawaharaMRegulated expression of two sets of paternally imprinted genes is necessary for mouse parthenogenetic development to termReproduction2006131348148816514191
   PubMed Web of Science ®Google Scholar
• StrainLWarnerJPJohnstonTBonthronDTA human parthenogenetic chimaeraNat Genet19951121641697550344
   PubMed Web of Science ®Google Scholar
• RevazovaESTurovetsNAKochetkovaODHLA Homozygous Stem Cell Lines Derived from Human Parthenogenetic BlastocystsCloning Stem Cells2008101112418092905
   PubMedGoogle Scholar
• HaoJZhuWShengCYuYZhouQHuman parthenogenetic embryonic stem cells: one potential resource for cell therapySci China C Life Sci200952759960219641863
   PubMedGoogle Scholar
• AllenNDBartonSCHiltonKNorrisMLSuraniMAA functional analysis of imprinting in parthenogenetic embryonic stem cellsDevelopment19941206147314828050357
   PubMed Web of Science ®Google Scholar
• KimKLerouPYabuuchiAHistocompatible embryonic stem cells by parthenogenesisScience2007315581148248617170255
   PubMed Web of Science ®Google Scholar
• ThomsonJASolterDThe developmental fate of androgenetic, parthenogenetic, and gynogenetic cells in chimeric gastrulating mouse embryosGenes Dev1988210134413513203909
   PubMed Web of Science ®Google Scholar
• MaiQYuYLiTDerivation of human embryonic stem cell lines from parthenogenetic blastocystsCell Res200717121008101918071366
   PubMed Web of Science ®Google Scholar
• LinGOuYangQZhouXA highly homozygous and parthenogenetic human embryonic stem cell line derived from a onepronuclear oocyte following in vitro fertilization procedureCell Res20071712999100718040289
   PubMed Web of Science ®Google Scholar
• HwangWSRohSILeeBCPatient-specific embryonic stem cells derived from human SCNT blastocystsScience200530857291777178315905366
   PubMed Web of Science ®Google Scholar
• KimKNgKRugg-GunnPJRecombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transferCell Stem Cell20071334635218371368
   PubMed Web of Science ®Google Scholar
• De SousaPAGardnerJSneddonSClinically failed eggs as a source of normal human embryo stem cellsStem Cell Res20092318819719393594
   PubMed Web of Science ®Google Scholar
• LinHLeiJWiningerDMultilineage potential of homozygous stem cells derived from metaphase II oocytesStem Cells200321215216112634411
   PubMed Web of Science ®Google Scholar
• RevazovaESTurovetsNAKochetkovaODHLA homozygous stem cell lines derived from human parthenogenetic blastocystsCloning Stem Cells2008101112418092905
   PubMedGoogle Scholar
• Suss-TobyEGerecht-NirSAmitMManorDItskovitz-EldorJDerivation of a diploid human embryonic stem cell line from a mononuclear zygoteHum Reprod200419367067514998969
   PubMed Web of Science ®Google Scholar
• McElroySLKeeKTranNMensesJGiudiceLCReijo PeraRADevelopmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transferReprod Biomed Online200816568469318492373
   PubMed Web of Science ®Google Scholar
• XingFFangZQinBLiYHouJChenXParthenogenetic embryonic stem cells derived from cryopreserved newborn mouse ovaries: a new approach to autologous stem cell therapyFertil Steril20099141238124418353322
   PubMed Web of Science ®Google Scholar
• de FriedEPRossPZangGHuman parthenogenetic blastocysts derived from noninseminated cryopreserved human oocytesFertil Steril200889494394717706204
   PubMed Web of Science ®Google Scholar
• MullerRLengerkeCPatient-specific pluripotent stem cells: promises and challengesNat Rev Endocrinol20095419520319352317
   PubMed Web of Science ®Google Scholar
• EckardtSLeuNABradleyHLKatoHBuntingKDMcLaughlinKJHematopoietic reconstitution with androgenetic and gynogenetic stem cellsGenes Dev200721440941917322401
   PubMed Web of Science ®Google Scholar
• KohCJDeloDMLeeJWParthenogenesis-derived multipotent stem cells adapted for tissue engineering applicationsMethods2009472909718799133
   PubMed Web of Science ®Google Scholar
• Sanchez-PernauteRLeeHPattersonMParthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson’s diseaseBrain2008131Pt 82127213918669499
   PubMed Web of Science ®Google Scholar
• BongsoAFongCYGauthamanKTaking stem cells to the clinic: Major challengesJ Cell Biochem200810561352136018980213
   PubMed Web of Science ®Google Scholar
• LoBGaranNHistorical perspective and evolving concerns for human researchCancer Treat Res200713211017305014
   PubMedGoogle Scholar
• ChaerkadyRKerrCLMarimuthuATemporal analysis of neural differentiation using quantitative proteomics (dagger)J Proteome Res2009831315132619173612
   PubMed Web of Science ®Google Scholar
• AasenTRayaABarreroMJEfficient and rapid generation of induced pluripotent stem cells from human keratinocytesNat Biotechnol200826111276128418931654
   PubMed Web of Science ®Google Scholar
• AliSHDeCaprioJACellular transformation by SV40 large T antigen: interaction with host proteinsSemin Cancer Biol2001111152311243895
   PubMed Web of Science ®Google Scholar
• KerrDALladoJShamblottMJHuman embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injuryJ Neurosci200323125131514012832537
   PubMed Web of Science ®Google Scholar
• MuellerDShamblottMJFoxHEGearhartJDMartinLJTransplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damageJ Neurosci Res200582559260816247803
   PubMed Web of Science ®Google Scholar
• FrimbergerDMoralesNShamblottMGearhartJDGearhartJPLakshmananYHuman embryoid body-derived stem cells in bladder regeneration using rodent modelUrology200565482783215833555
   PubMed Web of Science ®Google Scholar
• FurthMEAtalaAStem cell sources to treat diabetesJ Cell Biochem2009106450751119130494
   PubMed Web of Science ®Google Scholar
• LindvallOKokaiaZProspects of stem cell therapy for replacing dopamine neurons in Parkinson’s diseaseTrends Pharmacol Sci200930526026719362379
   PubMed Web of Science ®Google Scholar
• KarussisDKassisIThe potential use of stem cells in multiple sclerosis: an overview of the preclinical experienceClin Neurol Neurosurg2008110988989618375051
   PubMed Web of Science ®Google Scholar
• HwangNSVargheseSLeeHJIn vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cellsProc Natl Acad Sci U S A200810552206412064619095799
   PubMed Web of Science ®Google Scholar
• HwangNSElisseeffJApplication of stem cells for articular cartilage regenerationJ Knee Surg2009221607119216354
   PubMedGoogle Scholar
• KroonEMartinsonLAKadoyaKPancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivoNat Biotechnol200826444345218288110
   PubMed Web of Science ®Google Scholar
• KehatIKhimovichLCaspiOElectromechanical integration of cardiomyocytes derived from human embryonic stem cellsNat Biotechnol200422101282128915448703
   PubMed Web of Science ®Google Scholar
• LafammeMAGoldJXuCFormation of human myocardium in the rat heart from human embryonic stem cellsAm J Pathol2005167366367116127147
   PubMed Web of Science ®Google Scholar
• XueTChoHCAkarFGFunctional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakersCirculation20051111112015611367
   PubMed Web of Science ®Google Scholar
• LeorJGerechtSCohenSHuman embryonic stem cell transplantation to repair the infarcted myocardiumHeart200793101278128417566061
   PubMed Web of Science ®Google Scholar
• Ben-HurTIdelsonMKhanerHTransplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian ratsStem Cells20042271246125515579643
   PubMed Web of Science ®Google Scholar
• RoyNSClerenCSinghSKYangLBealMFGoldmanSAFunctional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytesNat Med200612111259126817057709
   PubMed Web of Science ®Google Scholar
• LiuSQuYStewartTJEmbryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantationProc Natl Acad Sci U S A200097116126613110823956
   PubMed Web of Science ®Google Scholar
• KeirsteadHSNistorGBernalGHuman embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injuryJ Neurosci200525194694470515888645
   PubMed Web of Science ®Google Scholar
• FaulknerJKeirsteadHSHuman embryonic stem cell-derived oligodendrocyte progenitors for the treatment of spinal cord injuryTranspl Immunol200515213114216412957
   PubMed Web of Science ®Google Scholar
• CloutierFSiegenthalerMMNistorGKeirsteadHSTransplantation of human embryonic stem cell-derived oligodendrocyte progenitors into rat spinal cord injuries does not cause harmRegen Med20061446947917465839
   PubMed Web of Science ®Google Scholar
• DaadiMMMaagALSteinbergGKAdherent self-renewable human embryonic stem cell-derived neural stem cell line: functional engraftment in experimental stroke modelPLoS One200832e164418286199
   PubMed Web of Science ®Google Scholar
• DaadiMMLeeSHAracAFunctional Engraftment of the Medial Ganglionic Eminence Cells in Experimental Stroke ModelCell Transplant200918781582619500468
   PubMed Web of Science ®Google Scholar
• HicksAULappalainenRSNarkilahtiSTransplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional recoveryEur J Neurosci200929356257419175403
   PubMed Web of Science ®Google Scholar
• OyamadaNItohHSoneMTransplantation of vascular cells derived from human embryonic stem cells contributes to vascular regeneration after stroke in miceJ Transl Med200865418823569
   PubMed Web of Science ®Google Scholar
• Soto-GutierrezAKobayashiNRivas-CarrilloJDReversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytesNat Biotechnol200624111412141917086173
   PubMed Web of Science ®Google Scholar
• VuglerACarrAJLawrenceJElucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantationExp Neurol2008214234736118926821
   PubMed Web of Science ®Google Scholar
• NistorGITotoiuMOHaqueNCarpenterMKKeirsteadHSHuman embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantationGlia200549338539615538751
   PubMed Web of Science ®Google Scholar
• AharonowizMEinsteinOFainsteinNNeuroprotective effect of transplanted human embryonic stem cell-derived neural precursors in an animal model of multiple sclerosisPLoS One200839e314518773082
   PubMed Web of Science ®Google Scholar
• CouzinJBiotechnology. Celebration and concern over US trial of embryonic stem cellsScience2009323591456819179496
   PubMed Web of Science ®Google Scholar
• TrounsonANew perspectives in human stem cell therapeutic researchBMC Med200972919519878
   PubMed Web of Science ®Google Scholar
• WernigMZhaoJPPruszakJNeurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson’s diseaseProc Natl Acad Sci U S A2008105155856586118391196
   PubMed Web of Science ®Google Scholar
• NelsonTJMartinez-FernandezAYamadaSPerez-TerzicCIkedaYTerzicARepair of acute myocardial infarction by human stemness factors induced pluripotent stem cellsCirculation2009120540841619620500
   PubMed Web of Science ®Google Scholar
• EbertADYuJRoseFFJrInduced pluripotent stem cells from a spinal muscular atrophy patientNature2009457722727728019098894
   PubMed Web of Science ®Google Scholar
• DimosJTRodolfaKTNiakanKKInduced pluripotent stem cells generated from patients with ALS can be differentiated into motor neuronsScience200832158931218122118669821
   PubMed Web of Science ®Google Scholar
• LeeGPapapetrouEPKimHModelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCsNature2009461726240240619693009
   PubMed Web of Science ®Google Scholar
• MaehrRChenSSnitowMGeneration of pluripotent stem cells from patients with type 1 diabetesProc Natl Acad Sci U S A2009106155231552419805208
   PubMed Web of Science ®Google Scholar
• HannaJWernigMMarkoulakiSTreatment of sickle cell anemia mouse model with iPS cells generated from autologous skinScience200731858581920192318063756
   PubMed Web of Science ®Google Scholar
• WangYJiangYLiuSSunXGaoSGeneration of induced pluripotent stem cells from human beta-thalassemia fibroblast cellsCell Res20091991120112319690515
   PubMed Web of Science ®Google Scholar
• CondicMLRaoMRegulatory issues for personalized pluripotent cellsStem Cells200826112753275818669906
   PubMed Web of Science ®Google Scholar
• FadenRRDawsonLBateman-HouseASPublic stem cell banks: considerations of justice in stem cell research and therapyHastings Cent Rep2003336132714983554
   PubMed Web of Science ®Google Scholar
• NakajimaFTokunagaKNakatsujiNHuman leukocyte antigen matching estimations in a hypothetical bank of human embryonic stem cell lines in the Japanese population for use in cell transplantation therapyStem Cells200725498398517185611
   PubMed Web of Science ®Google Scholar
• TaylorCJBoltonEMPocockSSharplesLDPedersenRABradleyJABanking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matchingLancet200536695022019202516338451
   PubMed Web of Science ®Google Scholar
• StruloviciYLeopoldPLO’ConnorTPPergolizziRGCrystalRGHuman embryonic stem cells and gene therapyMol Ther200715585086617356540
   PubMed Web of Science ®Google Scholar
• HarrisonNJBakerDAndrewsPWCulture adaptation of embryonic stem cells echoes germ cell malignancyInt J Androl200730427528117488340
   PubMedGoogle Scholar
• DraperJSSmithKGokhalePRecurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cellsNat Biotechnol2004221535414661028
   PubMed Web of Science ®Google Scholar
• BlumBBenvenistyNThe tumorigenicity of human embryonic stem cellsAdv Cancer Res200810013315818620095
   PubMed Web of Science ®Google Scholar
• SpitsCMateizelIGeensMRecurrent chromosomal abnormalities in human embryonic stem cellsNat Biotechnol200826121361136319029912
   PubMed Web of Science ®Google Scholar
• GreavesMFCord blood donor cell leukemia in recipientsLeukemia20062091633163416791267
   PubMed Web of Science ®Google Scholar
• BarozziPLuppiMFacchettiFPost-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitorsNat Med20039555456112692543
   PubMed Web of Science ®Google Scholar
• AvitalIMoreiraALKlimstraDSDonor-derived human bone marrow cells contribute to solid organ cancers developing after bone marrow transplantationStem Cells200725112903290917690178
   PubMed Web of Science ®Google Scholar
• GolfinopoulosVPentheroudakisGKamakariSMetaxa-MariatouVPavlidisNDonor-derived breast cancer in a bone marrow transplantation recipientBreast Cancer Res Treat2009113221121318264757
   PubMed Web of Science ®Google Scholar
• DubernardGAractingiSOsterMBreast cancer stroma frequently recruits fetal derived cells during pregnancyBreast Cancer Res2008101R1418271969
   PubMed Web of Science ®Google Scholar
• RoordaBDter ElstAKampsWAde BontESBone marrow-derived cells and tumor growth: contribution of bone marrow-derived cells to tumor micro-environments with special focus on mesenchymal stem cellsCrit Rev Oncol Hematol200969318719818675551
   PubMed Web of Science ®Google Scholar
• JohnsonKLBianchiDWFetal cells in maternal tissue following pregnancy: what are the consequences?Hum Reprod Update200410649750215319378
   PubMed Web of Science ®Google Scholar
• ChaDKhosrotehraniKKimYStrohHBianchiDWJohnsonKLCervical cancer and microchimerismObstet Gynecol2003102477478114551008
   PubMed Web of Science ®Google Scholar
• AmariglioNHirshbergAScheithauerBWDonor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patientPLoS Med200962e100002919226183
   PubMed Web of Science ®Google Scholar
• StilleyCSRyanCMKondziolkaDBenderADeCesareSWechslerLChanges in cognitive function after neuronal cell transplantation for basal ganglia strokeNeurology20046371320132215477565
   PubMed Web of Science ®Google Scholar
• WatsonDJLonghiLLeeEBGenetically modified NT2N human neuronal cells mediate long-term gene expression as CNS grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injuryJ Neuropathol Exp Neurol200362436838012722829
   PubMed Web of Science ®Google Scholar
• KondziolkaDWechslerLGoldsteinSTransplantation of cultured human neuronal cells for patients with strokeNeurology200055456556910953194
   PubMed Web of Science ®Google Scholar
• WechslerLRClinical trials of stroke therapy: which cells, which patients?Stroke2009403 SupplS149S15119064792
   PubMed Web of Science ®Google Scholar