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Original Research

Treatment of Chronic Spinal Cord Injury in Dogs Using Amniotic Membrane-Derived Stem Cells: Preliminary Results

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Pages 39-49 | Published online: 18 Oct 2021

References

  • Brisson BA. Intervertebral disc disease in dogs. Vet Clin North Am Small Anim Pract. 2010;40(5):829–858. doi:10.1016/j.cvsm.2010.06.001
  • Hansen H. A pathologic-anatomical study on disc degeneration in dog, with special reference to the so-called enchondrosis intervertebralis. Acta Orthop Scand Suppl. 1952;11:1–117. doi:10.3109/ort.1952.23.suppl-11.01
  • Fenn J, Olby NJ. Classification of intervertebral disc disease. Front Vet Sci. 2020;7. doi:10.3389/fvets.2020.579025
  • Olby NJ, De Risio L, Muñana KR, et al. Development of a functional scoring system in dogs with acute spinal cord injuries. Am J Vet Res. 2001;62(10):1624–1628. doi:10.2460/ajvr.2001.62.1624
  • Bezerra CH, Lopes RS, Franco A, et al. Levantamento de casos de janeiro a junho de 2012 atendidos na FisioCare Pet. Rev Educ Contin Med Vet Zoot CRMV-SP. 2013;11(2):71.
  • Caplan AI. Mesenchymal stem cells. J Orthop Res. 1991;9(5):641–650. doi:10.1002/jor.1100090504
  • Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement. Cytotherapy. 2006;8(4):315–317. doi:10.1080/14653240600855905
  • Nishida H, Nakayama M, Tanaka H, et al. Safety of autologous bone marrow stromal cell transplantation in dogs with acute spinal cord injury. Vet Surg. 2012;41(4):437–442. doi:10.1111/j.1532-950X.2011.00959.x
  • Bydlowski SP, Debes AA, Maselli LMF, Janz FL. Características biológicas das células-tronco mesenquimais. Rev Bras Hematol Hemoter. 2009;31:25–35. doi:10.1590/S1516-84842009005000038
  • Sarmento C, Rodrigues M, Bocabello R, Mess A, Miglino M. Pilot study: bone marrow stem cells as a treatment for dogs with chronic spinal cord injury. Regen Med Res. 2014;2(1):9. doi:10.1186/2050-490X-2-9
  • Lee SH, Kim Y, Rhew D, et al. Effect of the combination of mesenchymal stromal cells and chondroitinase ABC on chronic spinal cord injury. Cytotherapy. 2015;17(10):1374–1383. doi:10.1016/j.jcyt.2015.05.012
  • Hoffman AM, Dow SW. Concise review: stem cell trials using companion animal disease models. Stem Cells. 2016;34(7):1709–1729. doi:10.1002/stem.2377
  • Feitosa MLT, Sarmento CAP, Bocabello RZ, et al. Transplantation of human immature dental pulp stem cell in dogs with chronic spinal cord injury. Acta Cir Bras. 2017;32(7):540–549. doi:10.1590/s0102-865020170070000005
  • Escalhão CCM, Ramos IP, Hochman-Mendez C, et al. Safety of allogeneic canine adipose tissue-derived mesenchymal stem cell intraspinal transplantation in dogs with chronic spinal cord injury. Stem Cells Int. 2017;2017:1–11. doi:10.1155/2017/3053759
  • Ambrosio CE, Orlandin JR, Oliveira VC, et al. Potential application of aminiotic stem cells in veterinary medicine. Anim Reprod. 2018;16:24–30. Colegio Brasileiro de Reproducao Animal. doi:10.21451/1984-3143-AR2018-0124
  • Bach FS, Rebelatto CLK, Fracaro L, et al. Comparison of the efficacy of surgical decompression alone and combined with canine adipose tissue-derived stem cell transplantation in dogs with acute thoracolumbar disk disease and spinal cord injury. Front Vet Sci. 2019;6. doi:10.3389/fvets.2019.00383
  • Wu GH, Shi HJ, Che MT, et al. Recovery of paralyzed limb motor function in canine with complete spinal cord injury following implantation of MSC-derived neural network tissue. Biomaterials. 2018;181:15–34. doi:10.1016/j.biomaterials.2018.07.010
  • Bhat IA, Sivanarayanan TB, Somal A, et al. An allogenic therapeutic strategy for canine spinal cord injury using mesenchymal stem cells. J Cell Physiol. 2019;234(3):2705–2718. doi:10.1002/jcp.27086
  • Aralla M, Groppetti D, Caldarini L, Cremonesi F, Arrighi S. Morphological evaluation of the placenta and fetal membranes during canine pregnancy from early implantation to term. Res Vet Sci. 2013;95(1):15–22. doi:10.1016/j.rvsc.2013.02.003
  • Huo S, Shi P, Pang X. Culture and identification of human amniotic mesenchymal stem cells. Chin Med Sci J. 2010;25(4):211–214. doi:10.1016/S1001-9294(11)60004-7
  • Cremonesi F, Corradetti B, Lange Consiglio A. Fetal adnexa derived stem cells from domestic animal: progress and perspectives. Theriogenology. 2011;75(8):1400–1415. doi:10.1016/j.theriogenology.2010.12.032
  • Filioli Uranio M, Valentini L, Lange-Consiglio A, et al. Isolation, proliferation, cytogenetic, and molecular characterization and in vitro differentiation potency of canine stem cells from foetal adnexa: a comparative study of amniotic fluid, amnion, and umbilical cord matrix. Mol Reprod Dev. 2011;78(5):361–373. doi:10.1002/mrd.21311
  • Fernandes RA, Wenceslau CV, Reginato AL, Kerkis I, Miglino MA. Derivation and characterization of progenitor stem cells from canine allantois and amniotic fluids at the third trimester of gestation. Placenta. 2012;33(8):640–644. doi:10.1016/J.PLACENTA.2012.03.009
  • Lange-Consiglio A, Corradetti B, Bizzaro D, et al. Characterization and potential applications of progenitor-like cells isolated from horse amniotic membrane. J Tissue Eng Regen Med. 2012;6(8):622–635. doi:10.1002/term.465
  • Lange-Consiglio A, Corradetti B, Meucci A, Perego R, Bizzaro D, Cremonesi F. Characteristics of equine mesenchymal stem cells derived from amnion and bone marrow: in vitro proliferative and multilineage potential assessment. Equine Vet J. 2013;45(6):737–744. doi:10.1111/evj.12052
  • Vidane AS, Souza AF, Sampaio RV, et al. Cat amniotic membrane multipotent cells are nontumorigenic and are safe for use in cell transplantation. Stem Cells Cloning. 2014;7:71–78. doi:10.2147/SCCAA.S67790
  • Cardoso M, Pinheiro A, Vidane A, et al. Characterization of teratogenic potential and gene expression in canine and feline amniotic membrane-derived stem cells. Reprod Domest Anim. 2017;52:58–64. doi:10.1111/rda.12832
  • de Oliveira Pinheiro A, Lara VM, Souza AF, et al. Characterization and immunomodulation of canine amniotic membrane stem cells. Stem Cells Cloning Adv Appl. 2020;13:43–55. doi:10.2147/SCCAA.S237686
  • Soncini M, Vertua E, Gibelli L, et al. Isolation and characterization of mesenchymal cells from human fetal membranes. J Tissue Eng Regen Med. 2007;1(4):296–305. doi:10.1002/term.40
  • Lamb CR. Common difficulties with myelographic diagnosis of acute intervertebral disc prolapse in the dog. J Small Anim Pract. 1994;35(11):549–558. doi:10.1111/j.1748-5827.1994.tb03816.x
  • Bagley RS, Harrington ML, Silver GM, Cambridge AJ, Connors RL. Exogenous spinal trauma: clinical assessment and initial management. Compend Contin Educ Vet. 1999;21:1138–1144.
  • Lewis MJ, Cohen EB, Olby NJ. Magnetic resonance imaging features of dogs with incomplete recovery after acute, severe spinal cord injury. Spinal Cord. 2018;56(2):133–141. doi:10.1038/s41393-017-0004-8
  • Rosenblatt AJ, Bottema CDK, Hill PB. Radiographic scoring for intervertebral disc calcification in the dachshund. Vet J. 2014;200(3):355–361. doi:10.1016/j.tvjl.2014.03.023
  • Olby NJ, Dyce J, Houlton JEF. Correlation of plain radiographic and lumbar myelographic findings with surgical findings in thoracolumbar disc disease. J Small Anim Pract. 1994;35(7):345–350. doi:10.1111/j.1748-5827.1994.tb01713.x
  • Neshat Halati F, Vajhi A, Molazem M, Dehghan MM, Ansari F. Are magnetic resonance imaging or radiographic findings correlated with clinical prognosis in spinal cord neuropathy? Vet Res Forum an Int Q J. 2016;7(3):261–266.
  • Downes CJ, Gemmill TJ, Gibbons SE, McKee WM. Hemilaminectomy and vertebral stabilisation for the treatment of thoracolumbar disc protrusion in 28 dogs. J Small Anim Pract. 2009;50(10):525–535. doi:10.1111/j.1748-5827.2009.00808.x
  • Sankar V, Muthusamy R. Role of human amniotic epithelial cell transplantation in spinal cord injury repair research. Neuroscience. 2003;118(1):11–17. doi:10.1016/S0306-4522(02)00929-6
  • Yazdani SO, Pedram M, Hafizi M, et al. A comparison between neurally induced bone marrow derived mesenchymal stem cells and olfactory ensheathing glial cells to repair spinal cord injuries in rat. Tissue Cell. 2012;44(4):205–213. doi:10.1016/j.tice.2012.03.003
  • Meng X, Li C, Dong Z, et al. Co-transplantation of bFGF-expressing amniotic epithelial cells and neural stem cells promotes functional recovery in spinal cord-injured rats. Cell Biol Int. 2008;32(12):1546–1558. doi:10.1016/j.cellbi.2008.09.001
  • Orlandin JR, Ambrósio CE, Lara VM. Glial scar-modulation as therapeutic tool in spinal cord injury in animal models. Acta Cir Bras. 2017;32(2):168–174. doi:10.1590/s0102-865020170209
  • Wenceslau CV, Miglino MA, Martins DS, et al. Mesenchymal progenitor cells from canine fetal tissues: yolk sac, liver, and bone marrow. Tissue Eng Part A. 2011;17(17–18):2165–2176. doi:10.1089/ten.TEA.2010.0678
  • Park S-B, Seo M-S, Kim H-S, Kang K-S, Bauer JA. Isolation and characterization of canine amniotic membrane-derived multipotent stem cells. Bauer JA, ed. PLoS One. 2012;7(9):e44693. doi:10.1371/journal.pone.0044693
  • Vidane A, Pinheiro A, Casals J, et al. Transplantation of amniotic membrane-derived multipotent cells ameliorates and delays the progression of chronic kidney disease in cats. Reprod Domest Anim. 2017;52(S2):316–326. doi:10.1111/rda.12846
  • Fouad H, Sabry D, Elsetohy K, Fathy N. Therapeutic efficacy of amniotic membrane stem cells and adipose tissue stem cells in rats with chemically induced ovarian failure. J Adv Res. 2016;7(2):233–241. doi:10.1016/j.jare.2015.05.002
  • Kim JS, Kim JC, Hahn TW, Park WC. Amniotic membrane transplantation in infectious corneal ulcer. Cornea. 2001;20(7):720–726. doi:10.1097/00003226-200110000-00010
  • Chen H-C, Tan H-Y, Hsiao C-H, Huang SC-M, Lin -K-K, Ma DH-K. Amniotic membrane transplantation for persistent corneal ulcers and perforations in acute fungal keratitis. Cornea. 2006;25(5):564–572. doi:10.1097/01.ico.0000227885.19124.6f
  • Salehi SH, As’adi K, Mousavi SJ, Shoar S. Evaluation of amniotic membrane effectiveness in skin graft donor site dressing in burn patients. Indian J Surg. 2015;77(S2):427–431. doi:10.1007/s12262-013-0864-x
  • ElHeneidy H, Omran E, Halwagy A, Al-Inany H, Al-Ansary M, Gad A. Amniotic membrane can be a valid source for wound healing. Int J Womens Health. 2016;8:225–231. doi:10.2147/IJWH.S96636
  • Vines J, Aliprantis A, Gomoll A, Farr J. Cryopreserved amniotic suspension for the treatment of knee osteoarthritis. J Knee Surg. 2015;29(06):443–450. doi:10.1055/s-0035-1569481
  • Werber B. Amniotic tissues for the treatment of chronic plantar fasciosis and achilles tendinosis. J Sport Med (Hindawi Publ Corp. 2015;2015:219896. doi:10.1155/2015/219896
  • Lange-Consiglio A, Tassan S, Corradetti B, et al. Investigating the efficacy of amnion-derived compared with bone marrow-derived mesenchymal stromal cells in equine tendon and ligament injuries. Cytotherapy. 2013;15(8):1011–1020. doi:10.1016/j.jcyt.2013.03.002
  • Su C-F, Chang L-H, Kao C-Y, et al. Application of amniotic fluid stem cells in repairing sciatic nerve injury in minipigs. Brain Res. 2018;1678:397–406. doi:10.1016/j.brainres.2017.11.010
  • Winck CP, Amélia S, Lima F, et al. Células-tronco fetais de membrana amniótica: o futuro da medicina regenerativa [Amniotic membrane fetal stem cells: the future of regenerative medicine]. REB. 2014;7(3):321–329. Portuguese.
  • Wu Z, Hui G, Lu Y, Wu X, Guo L. Transplantation of human amniotic epithelial cells improves hindlimb function in rats with spinal cord injury. Chin Med J. 2006;119(24):2101–2107. doi:10.1097/00029330-200612020-00013
  • Fenn J, Laber E, Williams K, et al. Associations between anesthetic variables and functional outcome in dogs with thoracolumbar intervertebral disk extrusion undergoing decompressive hemilaminectomy. J Vet Intern Med. 2017;31:3. doi:10.1111/jvim.14677
  • Forterre F, Konar M, Spreng D, Jaggy A, Lang J. Influence of intervertebral disc fenestration at the herniation site in association with hemilaminectomy on recurrence in chondrodystrophic dogs with thoracolumbar disc disease: a Prospective MRI Study. Vet Surg. 2008;37(4):399–405. doi:10.1111/j.1532-950X.2008.00394.x
  • Brisson BA, Moffatt SL, Swayne SL, Parent JM. Recurrence of thoracolumbar intervertebral disk extrusion in chondrodystrophic dogs after surgical decompression with or without prophylactic fenestration: 265 cases (1995–1999). J Am Vet Med Assoc. 2004;224(11):1808–1814. doi:10.2460/javma.2004.224.1808
  • Scott HW, McKee WM. Laminectomy for 34 dogs with thoracolumbar intervertebral disc disease and loss of deep pain perception. J Small Anim Pract. 1999;40(9):417–422. doi:10.1111/j.1748-5827.1999.tb03114.x
  • Olby N, Levine J, Harris T, Muñana K, Skeen T, Sharp N. Long-term functional outcome of dogs with severe injuries of the thoracolumbar spinal cord: 87 cases (1996–2001). J Am Vet Med Assoc. 2003;222(6):762–769. doi:10.2460/javma.2003.222.762
  • Kazakos G, Polizopoulou ZS, Patsikas MN, Tsimopoulos G, Roubies N, Dessiris A. Duration and severity of clinical signs as prognostic indicators in 30 dogs with thoracolumbar disk disease after surgical decompression. J Vet Med Ser A. 2005;52(3):147–152. doi:10.1111/j.1439-0442.2005.00698.x
  • Arias MVB, Nishioka CM, Garcia CO, Reia AZ, Baraúna Júnior D, Marcasso RA. Avaliação dos resultados clínicos após cirurgia descompressiva em cães com doença de disco intervertebral [Evaluation of clinical results after descompression surgery in dogs with intervertebral disc disease]. Arq Bras Med Vet Zootec. 2007;59(6):1445–1450. Portuguese. doi:10.1590/S0102-09352007000600015
  • Olson L. Medicine: clearing a path for nerve growth. Nature. 2002;416(6881):589–590. doi:10.1038/416589a
  • Bennaim M, Porato M, Jarleton A, et al. Preliminary evaluation of the effects of photobiomodulation therapy and physical rehabilitation on early postoperative recovery of dogs undergoing hemilaminectomy for treatment of thoracolumbar intervertebral disk disease. Am J Vet Res. 2017;78(2):195–206. doi:10.2460/ajvr.78.2.195
  • Lim J-H, Muguet-Chanoit AC, Smith DT, Laber E, Olby NJ. Potassium channel antagonists 4-aminopyridine and the T-butyl carbamate derivative of 4-aminopyridine improve hind limb function in chronically non-ambulatory dogs; A blinded, placebo-controlled trial. Sabaawy HE, ed. PLoS One. 2014;9(12):e116139. doi:10.1371/journal.pone.0116139
  • Tsai L-C, Lin Y-W, Hsieh C-L. Effects of bee venom injections at acupoints on neurologic dysfunction induced by thoracolumbar intervertebral disc disorders in canines: a Randomized, Controlled Prospective Study. Biomed Res Int. 2015;2015:1–7. doi:10.1155/2015/363801
  • Olby NJ, Vaden SL, Williams K, et al. Effect of cranberry extract on the frequency of bacteriuria in dogs with acute thoracolumbar disk herniation: a randomized controlled clinical trial. J Vet Intern Med. 2017;31(1):60–68. doi:10.1111/jvim.14613
  • Prado C, Fratini P, de Sá Schiavo Matias G, et al. Combination of stem cells from deciduous teeth and electroacupuncture for therapy in dogs with chronic spinal cord injury: a pilot study. Res Vet Sci. 2019;123:247–251. doi:10.1016/j.rvsc.2019.01.011
  • Pinto PAF, Pereira VM, Motta LCB, et al. Mammalian yolk sac - an alternative source of stem cells. Braz J Vet Med. 2021;43:e001221. doi:10.29374/2527-2179.bjvm001221