References
- LadewigJKochPBrüstleOLeveling Waddington: the emergence of direct programming and the loss of cell fate hierarchiesNat Rev Mol Cell Biol2013144225236
- PatelMYangSAdvances in reprogramming somatic cells to induced pluripotent stem cellsStem Cell Rev20106336738020336395
- BoianiMSchölerHRRegulatory networks in embryo-derived pluripotent stem cellsNat Rev Mol Cell Biol200561187288416227977
- GepsteinLDerivation and potential applications of human embryonic stem cellsCirc Res2002911086687612433831
- NakagamiHNakagawaNTakeyaYModel of vasculogenesis from embryonic stem cells for vascular research and regenerative medicineHypertension200648111211916754788
- BruntKRWeiselRDLiRKStem cells and regenerative medicine – future perspectivesCan J Physiol Pharmacol201290332733522401558
- AtalaARegenerative medicine strategiesJ Pediatr Surg2012471172822244387
- KellerGEmbryonic stem cell differentiation: emergence of a new era in biology and medicineGenes Dev200519101129115515905405
- PillaiRGStem cells for ocular tissue engineering and regenerationCurr Top Med Chem201111131606162021446913
- PappaKIAnagnouNPNovel sources of fetal stem cells: where do they fit on the developmental continuum?Regen Med20094342343319438317
- YenBLYenMLHsuPJMultipotent human mesenchymal stromal cells mediate expansion of myeloid-derived suppressor cells via hepatocyte growth factor/c-Met and STAT3Stem Cell Reports20131213915124052949
- LengnerCJiPS cell technology in regenerative medicineAnn NY Acad Sci20101192384420392216
- TakahashiKYamanakaSInduction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factorsCell2006126466367616904174
- ChinMHMasonMJXieWInduced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signaturesCell Stem Cell20095111112319570518
- SaricTHeschelerJStem cells and nuclear reprogrammingMinim Invasive Ther Allied Technol2008172647818465442
- BilicJIzpisua BelmonteJCConcise review: Induced pluripotent stem cells versus embryonic stem cells: close enough or yet too far apart?Stem Cells2012301334122213481
- YuJThomsonJAPluripotent stem cell linesGenes Dev200822151987199718676805
- RufaihahAJHuangNFKimJHuman induced pluripotent stem cell-derived endothelial cells exhibit functional heterogeneityAm J Transl Res201351213523390563
- HuBYWeickJPYuJNeural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potencyProc Natl Acad Sci U S A201010794335434020160098
- ZhangJWilsonGFSoerensAGFunctional cardiomyocytes derived from human induced pluripotent stem cellsCirc Res20091044e30e4119213953
- AzhdariMBaghaban-EslaminejadMBaharvandHAghdamiNTherapeutic potential of human-induced pluripotent stem cell-derived endothelial cells in a bleomycin-induced scleroderma mouse modelStem Cell Res201310328830023396195
- JuopperiTASongHMingGLModeling neurological diseases using patient-derived induced pluripotent stem cellsFuture Neurol20116336337321731471
- ColladoMBlascoMASerranoMCellular senescence in cancer and agingCell2007130222323317662938
- OkanoHNakamuraMYoshidaKSteps toward safe cell therapy using induced pluripotent stem cellsCirc Res2013112352353323371901
- SolterDMammalian cloning: advances and limitationsNat Rev Genet20001319920711252749
- VierbuchenTOstermeierAPangZPKokubuYSüdhofTCWernigMDirect conversion of fibroblasts to functional neurons by defined factorsNature201046372841035104120107439
- IedaMFuJDDelgado-OlguinPDirect reprogramming of fibroblasts into functional cardiomyocytes by defined factorsCell2010142337538620691899
- SekiyaSSuzukiADirect conversion of mouse fibroblasts to hepatocyte-like cells by defined factorsNature2011475735639039321716291
- NamYJSongKLuoXReprogramming of human fibroblasts toward a cardiac fateProc Natl Acad Sci U S A2013110145588559323487791
- QianLHuangYSpencerCIIn vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytesNature2012485740059359822522929
- GehringWJThe master control gene for morphogenesis and evolution of the eyeGenes Cells19961111159078363
- SchneuwlySKlemenzRGehringWJRedesigning the body plan of Drosophila by ectopic expression of the homoeotic gene AntennapediaNature198732561078168183821869
- YamanakaSBlauHMNuclear reprogramming to a pluripotent state by three approachesNature2010465729970471220535199
- DavisRLWeintraubHLassarABExpression of a single transfected cDNA converts fibroblasts to myoblastsCell198751698710003690668
- GurdonJBAdult frogs derived from the nuclei of single somatic cellsDev Biol1962425627313903027
- BlauHMPavlathGKHardemanECPlasticity of the differentiated stateScience198523047277587662414846
- BriggsRKingTJTransplantation of living nuclei from blastula cells into enucleated frogs’ eggsProc Natl Acad Sci U S A195238545546316589125
- ChoiJCostaMLMermelsteinCSChagasCHoltzerSHoltzerHMyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubesProc Natl Acad Sci U S A19908720798879922172969
- SchäferBWBlakelyBTDarlingtonGJBlauHMEffect of cell history on response to helix-loop-helix family of myogenic regulatorsNature199034462654544582157160
- KulessaHFramptonJGrafTGATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblastsGenes Dev1995910125012627758949
- XieHYeMFengRGrafTStepwise reprogramming of B cells into macrophagesCell2004117566367615163413
- NuttSLHeaveyBRolinkAGBusslingerMCommitment to the B-lymphoid lineage depends on the transcription factor Pax5Nature1999401675355656210524622
- CobaledaCJochumWBusslingerMConversion of mature B cells into T cells by dedifferentiation to uncommitted progenitorsNature2007449716147347717851532
- ZhouQBrownJKanarekARajagopalJMeltonDAIn vivo reprogramming of adult pancreatic exocrine cells to beta-cellsNature2008455721362763218754011
- SongKNamYJLuoXHeart repair by reprogramming non-myocytes with cardiac transcription factorsNature2012485740059960422660318
- ProtzeSKhattakSPouletCLindemannDTanakaEMRavensUA new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cellsJ Mol Cell Cardiol201253332333222575762
- AddisRCEpsteinJAInduced regeneration – the progress and promise of direct reprogramming for heart repairNat Med201319782983623836233
- InagawaKMiyamotoKYamakawaHInduction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5Circ Res201211191147115622931955
- MathisonMGerschRPNasserAIn vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factorJ Am Heart Assoc201216e00565223316332
- MummeryCWard-van OostwaardDDoevendansPDifferentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cellsCirculation2003107212733274012742992
- NarazakiGUosakiHTeranishiMDirected and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cellsCirculation2008118549850618625891
- ChenJXKraneMDeutschMAInefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5Circ Res20121111505522581928
- YiBAMummeryCLChienKRDirect cardiomyocyte reprogramming: a new direction for cardiovascular regenerative medicineCold Spring Harb Perspect Med201339a01405024003244
- JayawardenaTMEgemnazarovBFinchEAMicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytesCirc Res2012110111465147322539765
- MargaritiAWinklerBKaramaritiEDirect reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vesselsProc Natl Acad Sci U S A201210934137931379822869753
- GrafTEnverTForcing cells to change lineagesNature2009462727358759419956253
- HoLCrabtreeGRChromatin remodelling during developmentNature2010463728047448420110991
- TakahashiKOkitaKNakagawaMYamanakaSInduction of pluripotent stem cells from fibroblast culturesNat Protoc20072123081308918079707
- CherryABDaleyGQReprogramming cellular identity for regenerative medicineCell201214861110112222424223
- SheridanWSDuffyGPMurphyBPMechanical characterization of a customized decellularized scaffold for vascular tissue engineeringJ Mech Behav Biomed Mater20128587022402154
- NovoselECKleinhansCKlugerPJVascularization is the key challenge in tissue engineeringAdv Drug Deliv Rev2011634–530031121396416
- LiJHuangNFZouJConversion of human fibroblasts to functional endothelial cells by defined factorsArterioscler Thromb Vasc Biol20133361366137523520160
- KaramaritiEMargaritiAWinklerBSmooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular graftsCirc Res2013112111433144323529184
- GinsbergMJamesDDingBSEfficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppressionCell2012151355957523084400
- IgnarroLJBalestrieriMLNapoliCNutrition, physical activity, and cardiovascular disease: an updateCardiovasc Res200773232634016945357
- RasmussenTLRaveendranGZhangJGarryDJGetting to the heart of myocardial stem cells and cell therapyCirculation2011123161771177921518990
- CinesDBPollakESBuckCAEndothelial cells in physiology and in the pathophysiology of vascular disordersBlood19989110352735619572988
- DavignonJGanzPRole of endothelial dysfunction in atherosclerosisCirculation200410923 Suppl 1III27III3215198963
- WeberCNoelsHAtherosclerosis: current pathogenesis and therapeutic optionsNat Med201117111410142222064431
- WongWTHuangNFBothamCMSayedNCookeJPEndothelial cells derived from nuclear reprogrammingCirc Res2012111101363137523104878
- PawlowskiMKotterMGeneration of neural cells by direct cellular reprogrammingJ Transplant Stem Cell Biol2013117
- ButelJSViral carcinogenesis: revelation of molecular mechanisms and etiology of human diseaseCarcinogenesis200021340542610688861
- SrivastavaDIedaMCritical factors for cardiac reprogrammingCirc Res201211115822723217
- YanXQinHQuCTuanRSShiSHuangGTiPS cells reprogrammed from human mesenchymal-like stem/progenitor cells of dental tissue originStem Cells Dev201019446948019795982
- AddisRCIfkovitsJLPintoFOptimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of successJ Mol Cell Cardiol2013609710623591016
- ZhangYLiWLaurentTDingSSmall molecules, big roles – the chemical manipulation of stem cell fate and somatic cell reprogrammingJ Cell Sci2012125Pt 235609562023420199
- ShiYDespontsCDoJTHahmHSSchölerHRDingSInduction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compoundsCell Stem Cell20083556857418983970
- SunGFuCShenCShiYHistone deacetylases in neural stem cells and induced pluripotent stem cellsJ Biomed Biotechnol2011201183596821845024
- MikkelsenTSHannaJZhangXDissecting direct reprogramming through integrative genomic analysisNature20084547200495518509334
- HuangfuDOsafuneKMaehrRInduction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2Nat Biotechnol200826111269127518849973
- NiwaHWnt: what’s needed to maintain pluripotency?Nat Cell Biol20111391024102621892143
- LiWZhouHAbujarourRGeneration of human-induced pluripotent stem cells in the absence of exogenous Sox2Stem Cells200927122992300019839055
- LyssiotisCAForemanRKStaerkJReprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4Proc Natl Acad Sci U S A2009106228912891719447925
- XieLLawBKChytilAMBrownKAAakreMEMosesHLActivation of the Erk pathway is required for TGF-beta1-induced EMT in vitroNeoplasia20046560361015548370
- IchidaJKBlanchardJLamKA small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanogCell Stem Cell20095549150319818703
- MaheraliNHochedlingerKTgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMycCurr Biol200919201718172319765992
- LinTAmbasudhanRYuanXA chemical platform for improved induction of human iPSCsNat Methods200961180580819838168
- LiuMLZangTZouYSmall molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neuronsNat Commun20134218323873306
- ZhuSLiWZhouHReprogramming of human primary somatic cells by OCT4 and chemical compoundsCell Stem Cell20107665165521112560
- YoshidaYTakahashiKOkitaKIchisakaTYamanakaSHypoxia enhances the generation of induced pluripotent stem cellsCell Stem Cell20095323724119716359
- SmithAWHoyneJDNguyenPKDirect reprogramming of mouse fibroblasts to cardiomyocyte-like cells using Yamanaka factors on engineered poly(ethylene glycol) (PEG) hydrogelsBiomaterials201334286559657123773820
- SuGZhaoYWeiJDirect conversion of fibroblasts into neural progenitor-like cells by forced growth into 3D spheres on low attachment surfacesBiomaterials201334245897590623680365
- ZhangKLiuGHYiFDirect conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factorsProtein Cell Epub6202013
- YuJVodyanikMASmuga-OttoKInduced pluripotent stem cell lines derived from human somatic cellsScience200731858581917192018029452
- SoldnerFHockemeyerDBeardCParkinson’s disease patient-derived induced pluripotent stem cells free of viral reprogramming factorsCell2009136596497719269371
- WarrenLManosPDAhfeldtTHighly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNACell Stem Cell20107561863020888316
- YakubovERechaviGRozenblattSGivolDReprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factorsBiochem Biophys Res Commun2010394118919320188704
- Anokye-DansoFTrivediCMJuhrDHighly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotencyCell Stem Cell20118437638821474102
- MiyoshiNIshiiHNaganoHReprogramming of mouse and human cells to pluripotency using mature microRNAsCell Stem Cell20118663363821620789
- ZhouHWuSJooJYGeneration of induced pluripotent stem cells using recombinant proteinsCell Stem Cell20094538138419398399
- KimKDoiAWenBEpigenetic memory in induced pluripotent stem cellsNature2010467731328529020644535
- OhiYQinHHongCIncomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cellsNat Cell Biol201113554154921499256
- BlumBBenvenistyNThe tumorigenicity of human embryonic stem cellsAdv Cancer Res200810013315818620095