Evaluation of NLRP3 (rs10754558) and PTPN22 (1858C/T) (rs2476601) Functional Polymorphisms in Psoriasis Susceptibility in Egypt

References

• Menter A, Gottlieb A, Feldman SR, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics. J Am Acad Dermatol. 2008;58:826–850. doi:10.1016/j.jaad.2008.02.039
   PubMed Web of Science ®Google Scholar
• Harden JL, Krueger JG, Bowcock AM. The immunogenetics of psoriasis: a comprehensive review. J Autoimmun. 2015;64:66–73. doi:10.1016/j.jaut.2015.07.008
   PubMed Web of Science ®Google Scholar
• Boehncke WH, Schön MP. Psoriasis. Lancet. 2015;386:983–994. doi:10.1016/S0140-6736(14)61909-7
   PubMed Web of Science ®Google Scholar
• Su F, Xia Y, Huang M, Zhang L, Chen L. Expression of NLPR3 in psoriasis is associated with enhancement of Interleukin-1beta and Caspase-1. Med Sci Monit. 2018;24:7909–7913. doi:10.12659/MSM.911347
   PubMed Web of Science ®Google Scholar
• Yu P, Hao S, Zheng H, Zhao X. Association of NLRP1 and NLRP3 polymorphisms with psoriasis vulgaris risk in the chinesehan population. Biomed Res Int. 2018;4:714–836.
   Google Scholar
• Cohen S, Dadi H, Shaoul E, Sharfe N, Roifman CM. Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp. Blood. 1999;93:2013–2024. doi:10.1182/blood.V93.6.2013.406k25_2013_2024
   PubMed Web of Science ®Google Scholar
• Bianco B, Verreschi IT, Oliveira KC, et al. PTPN22 polymorphism is related to autoimmune disease risk in patients with Turner syndrome. Scand J Immunol. 2010;72:256–259. doi:10.1111/j.1365-3083.2010.02438.x
   PubMed Web of Science ®Google Scholar
• Pradhan V, Borse V, Ghosh K. PTPN22 gene polymorphisms in autoimmune diseases with special reference to systemic lupus erythematosus disease susceptibility. J Postgrad Med. 2010;56:239–242. doi:10.4103/0022-3859.68651
   PubMed Web of Science ®Google Scholar
• Fredriksson T, Pettersson U. Severe psoriasis- oral therapy with a new retinoid. Dermatology. 1978;157:238–244. doi:10.1159/000250839
   Web of Science ®Google Scholar
• ipsogen® RT Kit Handbook. QIAGEN GmbH; 2015. Available from: http://rcostoya.com/uploads/galerias/con812/hb-1356-003-1072504-151021522-r3-ipsogen-rt-kit-ce-0315-row.pdf.
   Google Scholar
• Afonina I, Zivarts M, Kutyavin I, Lukhtanov E, Gamper H, Meyer RB. Efficient priming of PCR with short oligonucleotides conjugated to a minor groove binder. Nucleic Acids Res. 1997;25(13):2657–2660. doi:10.1093/nar/25.13.2657
   PubMed Web of Science ®Google Scholar
• Bin Huraib G, Al Harthi F, Arfin M, Rizvi S, Al-Asmari A. The protein tyrosine phosphatase nonreceptor 22 (PTPN22) R620W functional polymorphism in psoriasis. Clin Med Insights Arthritis Musculoskelet Disord. 2017;11:1–6.
   Web of Science ®Google Scholar
• Lowes MA, Suárez-Fariñas M, Krueger JG. Immunology of psoriasis. Ann Rev Immunol. 2014;32:227–255. doi:10.1146/annurev-immunol-032713-120225
   PubMed Web of Science ®Google Scholar
• Chandy S, Song J. Association of NLRP1 and NLRP3 gene polymorphism with psoriasis. Our Dermatol Online. 2020;11(3):275–283. doi:10.7241/ourd.20203.13
   Google Scholar
• Bitto A, Altavilla D, Pizzino G, et al. Inhibition of inflammasome activation improves the impaired pattern of healing in genetically diabetic mice. Br J Pharmacol. 2014;171:2300–2307. doi:10.1111/bph.12557
   Web of Science ®Google Scholar
• Chiazza F, Couturier-Maillard A, Benetti E, et al. Targeting the NLRP3 inflammasome to reduce diet-induced metabolic abnormalities in mice. Mol Med. 2015;21:1025–1037. doi:10.2119/molmed.2015.00104
   Web of Science ®Google Scholar
• Villani A, Lemire M, Fortin G, et al. Common variants in the NLRP3 region contribute to Crohn’s disease susceptibility. Nat Genet. 2009;41(1):71–76. doi:10.1038/ng285
   PubMed Web of Science ®Google Scholar
• Lee YH, Bae SC. Association between functional NLRP3 polymorphisms and susceptibility to autoimmune and inflammatory diseases: a meta-analysis. Lupus. 2016;25:1558–1566.
   PubMed Web of Science ®Google Scholar
• Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn’s disease. Nature. 2001;411(6837):603–606. doi:10.1038/35079114
   PubMed Web of Science ®Google Scholar
• Roberts RL, Van Rij AM, Phillips LV, et al. Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms. Atherosclerosis. 2011;218(1):123–126. doi:10.1016/j.atherosclerosis.2011.04.043
   Web of Science ®Google Scholar
• Ravimohan S, Nfanyana K, Tamuhla N, Tiemessen CT, Weissma D, Bisson GP. Common variation in NLRP3Is associated with early death and elevated inflammasome biomarkers among advanced HIV/TB co-infected patients in Botswana. Open Forum Infect Dis. 2018;5:75. doi:10.1093/ofid/ofy075
   Web of Science ®Google Scholar
• Irrera N, Vaccaro M, Bitto A, et al. BAY 11-7082 inhibits the NF-κB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis. Clin Sci. 2017;131:487–498. doi:10.1042/CS20160645
   PubMed Web of Science ®Google Scholar
• Paramel GV, Sirsjö A, Fransén K. Role of genetic alterations in the NLRP3 and CARD8 genes in health and disease. Mediators Inflamm. 2015;2015:846782.
   Web of Science ®Google Scholar
• Hitomi Y, Ebisawa M, Tomikawa M, et al. Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. J Allerg Clin Immunol. 2009;124(4):779–785. doi:10.1016/j.jaci.2009.07.044
   PubMed Web of Science ®Google Scholar
• Verma D, Lerm M, Julinder RB, Eriksson P, Söderkvist P, Särndahl E. Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation relation to common inflammatory diseases? Arthritis Rheum. 2008;58(3):888–894. doi:10.1002/art.23286
   PubMed Web of Science ®Google Scholar
• Perera AP, Kunde D, Eri R. NLRP3 inhibitors as potential therapeutic agents for treatment of inflammatory bowel disease. Curr Pharm Des. 2017;23:2321–2327. doi:10.2174/1381612823666170201162414
   Web of Science ®Google Scholar
• Liu L, Dong Y, Ye M, et al. The pathogenic role of NLRP3 inflammasome activation in inflammatory bowel diseases of both mice and humans. J Crohns Colitis. 2017;11:737–750. doi:10.1093/ecco-jcc/jjw219
   PubMed Web of Science ®Google Scholar
• Verma D, Fekri SZ, Sigurdardottir G, Eding CB, Sandin C, Enerbäck C. Enhanced inflammasome activity in patients with psoriasis promotes systemic inflammation. J Invest Dermatol. 2020;141:586–595.e5. doi:10.1016/j.jid.2020.07.012
   Web of Science ®Google Scholar
• Loft ND, Skov L, Iversen L, et al. Associations between functional polymorphisms and response to biological treatment in Danish patients with psoriasis. Pharmacogenomics J. 2018;18:494–500. doi:10.1038/tpj.2017.31
   PubMed Web of Science ®Google Scholar
• Spalinger M, Lang S, Gottier C, et al. PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner. Autophagy. 2017;13:1590–1601. doi:10.1080/15548627.2017.1341453
   PubMed Web of Science ®Google Scholar
• Vang T, Congia M, Macis MD, et al. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat Genet. 2005;37(12):1317–1319. doi:10.1038/ng1673
   PubMed Web of Science ®Google Scholar
• Loft N, Skov L, Rasmussen M, et al. Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis. PLoS One. 2018;13:e0192010. doi:10.1371/journal.pone.0192010
   PubMed Web of Science ®Google Scholar
• Stuart PE, Nair RP, Tsoi LC, et al. Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture. Am J Hum Genet. 2015;97(6):816. doi:10.1016/j.ajhg.2015.10.019
   PubMed Web of Science ®Google Scholar
• Bowes J, Loehr S, Budu-Aggrey A, et al. PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus. Ann Rheum Dis. 2015;74(10):1882–1885. doi:10.1136/annrheumdis-2014-207187 PMID: 25923216; PubMed Central PMCID: PMCPMC4602265.
   PubMed Web of Science ®Google Scholar
• Zheng J, Ibrahim S, Petersen F, Yu X. Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue. Genes Immun. 2012;13:641–652. doi:10.1038/gene.2012.46
   PubMed Web of Science ®Google Scholar
• Chen YF, Chang JS. PTPN22 C1858T and the risk of psoriasis: a meta-analysis. Mol Biol Rep. 2012;39(8):7861–7870. doi:10.1007/s11033-012-1630-z
   Web of Science ®Google Scholar
• Al-Awadhi A, Haider M, Sukumaran J, Mohammed A, Hasan E, Bartella Y. Role of Protein Tyrosine Phosphatase (PTPN22) gene [C1858T] functional variant in genetic susceptibility of psoriatic arthritis in Kuwaiti Arabs. Open Rheumatol J. 2020;14:15–21. doi:10.2174/1874312902014010015
   Google Scholar