The risk reduction of recurrent periodontal pathogens of local application minocycline HCl 2% gel, used as an adjunct to scaling and root planing for chronic periodontitis treatment

References

• SocranskySHaffajeeADCuginiMASmithCKentRLJrMicrobial complexes in subgingival plaqueJ Clin Periodontol199825Suppl 21341449495612
   PubMed Web of Science ®Google Scholar
• SlotsJSubgingival microflora and periodontal diseaseJ Clin Periodontol19796351356393729
   PubMed Web of Science ®Google Scholar
• RadvarMPourtaghiNKinaneDFComparison of three periodontal local antibiotic therapies in resistant periodontal pocketsJ Periodontol1996678608658884642
   PubMed Web of Science ®Google Scholar
• TimmermanMFWeijdenGASteenbergenTJMantelMSde GraaffJVeldenUEvaluation of the long-term efficacy and safety of locally-applied minocycline in adult periodontitis patientsJ Clin Periodontol1996237077168877655
   PubMed Web of Science ®Google Scholar
• SteenbergheDVBercyPKohlJSubgingival minocycline hydrochloride ointment in moderate to severe chronic adult periodontitis: a randomized, double-blind, vehicle-controlled, multicenter studyJ Periodontol19936476376448396177
   PubMed Web of Science ®Google Scholar
• NakagawaTYamadaSOosukaYClinical and microbiological study of local minocycline delivery (Periocline) following scaling and root planing in recurrent periodontal pocketsBull Tokyo Dent Coll199132263701819445
   PubMedGoogle Scholar
• JonesAAKornmanKSNewboldDAManwellMAClinical and microbiological effects of controlled-release locally delivered minocycline in periodontitisJ Periodontol199465105810667853130
   PubMed Web of Science ®Google Scholar
• GracaMAWattsTLWilsonRFPalmerRMA randomized controlled trial of a 2% minocycline gel as an adjunct to non-surgical periodontal treatment, using a design with multiple matching criteriaJ Clin Periodontol1997242492539144047
   PubMed Web of Science ®Google Scholar
• WilliamsRCPaquetteDWOffenbacherSTreatment of periodontitis by local administration of minocycline microspheres: a controlled trialJ Periodontol2001721535154411759865
   PubMed Web of Science ®Google Scholar
• PaquetteDOringerRLessemJLocally delivered minocycline microspheres for the treatment of periodontitis in smokersJ Clin Periodontol20033078779412956654
   PubMed Web of Science ®Google Scholar
• StabholzAKetteringJAprecioRZimmermanGBakerPJWikesjoUMAntimicrobial properties of human dentin impregnated with tetracycline HCl or chlorhexidine. An in vitro studyJ Clin Periodontol1993205575628408717
   PubMed Web of Science ®Google Scholar
• ChoiDHMoonISChoiBKEffects of sub-antimicrobial dose doxycycline therapy on crevicular fluid MMP-8, and gingival tissue MMP-9, TIMP-1 and IL-6 levels in chronic periodontitisJ Periodontol Res2004392026
   PubMed Web of Science ®Google Scholar
• AbbasSMahendraJAriGMinocycline ointment as a local drug delivery in the treatment of generalized chronic periodontitis – a clinical studyJ Clin Diagn Res2016106ZC15ZC19
   PubMedGoogle Scholar
• PetersilkaGJEhmkeBFlemmigTFAntimicrobial effects of mechanical debridementPeriodontol. 2000200228567112013348
   PubMed Web of Science ®Google Scholar
• PeterEBettinaDTi-SunKAntibiotics in periodontal therapyPERIO200524235251
   Google Scholar
• LöeHThe gingival index, the plaque index and the retention index systemsJ Periodontol1967386 Suppl610616
   Web of Science ®Google Scholar
• MuhlemannHRSonSGingival sulcus bleeding – a leading symptom in initial gingivitisHelv Odontol Acta19711521071135315729
   PubMedGoogle Scholar
• ByrneSJDashperSGDarbyIBAdamsGGHoffmannBReynoldsECProgression of chronic periodontitis can be predicted by the levels of Porphyromonas gingivalis and Treponema denticola in subgingival plaqueOral Microbiol Immunol20092446947719832799
   PubMedGoogle Scholar
• AdriaensPADe BoeverJALoescheWJBacterial invasion in cementum and radicular dentin of periodontally diseased teeth in humansJ Periodontol1988592222303164373
   PubMed Web of Science ®Google Scholar
• MorilloJMLauLSanzMHerreraDSilvaAQuantitative real-time PCR based on single copy gene sequence for detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalisJ Periodontal Res20033851852412941077
   PubMed Web of Science ®Google Scholar
• ShelburneCEPrabhuAGleasonRMMullallyBHCoulterWAQuantitation of Bacteroides forsythus in subgingival plaque comparison of immunoassay and quantitative polymerase chain reactionJ Microbiol Methods2000399710710576699
   PubMed Web of Science ®Google Scholar
• KurataHAwanoSYoshidaAAnsaiTTakeharaTThe prevalence of periodontopathogenic bacteria in saliva is linked to periodontal health status and oral malodourJ Med Microbiol20085763664218436598
   PubMed Web of Science ®Google Scholar
• PiantadosiSSample size and powerPiantadosi Steven Clinical Trials: A Methodologic Perspective2nd edHoboken, NJJohn Wiley and Sons, Inc2005
   Google Scholar
• NakaoRTakigawaSSuganoNImpact of minocycline ointment for periodontal treatment of oral bacteriaJpn J Infect Dis201164215616021519133
   PubMed Web of Science ®Google Scholar
• CortelliJRQueridoSMAquinoDRRicardoLHPallosDLongitudinal clinical evaluation of adjunct minocycline in the treatment of chronic periodontitisJ Periodontol20067716116616460239
   PubMed Web of Science ®Google Scholar
• EickSRenatusAHeinickeMPfisterWStratulSIJentschHHyaluronic acid as an adjunct after scaling and root planing: a prospective randomized clinical trialJ Periodontol201384794194923088524
   PubMed Web of Science ®Google Scholar
• SteenbergheDVRoslingBSoderPOA 15-month evaluation of the effects of repeated subgingival minocycline in chronic adult periodontitisJ Periodontol19997065766710397521
   PubMed Web of Science ®Google Scholar
• SugiNNaruishiKKudoCPrognosis of periodontitis recurrence after intensive periodontal treatment using examination of serum IgG antibody titer against periodontal bacteriaJ Clin Lab Anal201125253221254239
   PubMed Web of Science ®Google Scholar
• Matesanz-PérezPGarcía-GargalloMFigueroEBascones-MartínezASanzMHerreraDA systematic review on the effects of local anti-microbials as adjuncts to subgingival debridement, compared with subgingival debridement alone, in the treatment of chronic periodontitisJ Clin Periodontol20134022724123320860
   PubMed Web of Science ®Google Scholar