Surgical Treatment of Clavicular Fractures, Refractures, Delayed and Non-Unions Using a Resorbable, Gentamicin-Eluting Calcium Sulphate/Hydroxyapatite Biocomposite

References

• Matthes G, Müller-Mai CM. Clavicula. In: Müller-Mai C, Ekkernkamp A, editors. Frakturen: Klassifikationen Und Behandlungsoptionen[Fractures: Classifications and treatment options]. Heidelberg: Springer; 2010:417–426.
   Google Scholar
• Nordqvist A, Petersson C. The incidence of fractures of the clavicle. Clin Orthop Relat Res. 1994;300:127–132. doi:10.1097/00003086-199403000-00016
   PubMed Web of Science ®Google Scholar
• van der Meijden OA, Gaskill TR, Millett PJ. Treatment of clavicle fractures: current concepts review. J Shoulder Elbow Surg. 2012;21(3):423–429. doi:10.1016/j.jse.2011.08.053
   PubMed Web of Science ®Google Scholar
• Khan LA, Bradnock TJ, Scott C, Robinson CM. Fractures of the clavicle. J Bone Joint Surg Am. 2009;91(2):447–460. doi:10.2106/JBJS.H.00034
   PubMed Web of Science ®Google Scholar
• Allman FL Jr. Fractures and ligamentous injuries of the clavicle and its articulation. J Bone Joint Surg Am. 1967;49(4):774–784. doi:10.2106/00004623-196749040-00024
   PubMed Web of Science ®Google Scholar
• Neer CS 2nd. Fractures of the distal third of the clavicle. Clin Orthop Relat Res. 1968;58:43–50. doi:10.1097/00003086-196805000-00007
   PubMedGoogle Scholar
• Jäger M, Breitner S. Therapiebezogene Klassifikation der lateralen Claviculafraktur [Therapy related classification of lateral clavicular fracture]. Unfallheilkunde. 1984;87(11):467–473.
   PubMedGoogle Scholar
• Postacchini F, Gumina S, De Santis P, Albo F. Epidemiology of clavicle fractures. J Shoulder Elbow Surg. 2002;11(5):452–456. doi:10.1067/mse.2002.126613
   PubMed Web of Science ®Google Scholar
• Robinson CM. Fractures of the clavicle in the adult. Epidemiology and classification. J Bone Joint Surg Br. 1998;80(3):476–484. doi:10.1302/0301-620X.80B3.0800476
   PubMed Web of Science ®Google Scholar
• Bakir MS, Merschin D, Unterkofler J, et al. Injuries of the medial clavicle: a cohort analysis in a level-I-trauma-center. concomitant injuries. management. classification. Chirurgia. 2017;112(5):594. doi:10.21614/chirurgia.112.5.586
   PubMed Web of Science ®Google Scholar
• Zlowodzki M, Zelle BA, Cole PA, Jeray K, McKee MD; Evidence-Based Orthopaedic Trauma Working Group. Treatment of acute midshaft clavicle fractures: systematic review of 2144 fractures: on behalf of the evidence-based orthopaedic trauma working group. J Orthop Trauma. 2005;19(7):504–507. doi:10.1097/01.bot.0000172287.44278.ef
   PubMed Web of Science ®Google Scholar
• Jeray KJ, Hill AD. Complications of clavicle fractures—Diagnosis and management. In: Disorders of the Shoulder: Trauma. Vol. 3. Wolters Kluwer Health Adis (ESP); 2013:135–150.
   Google Scholar
• Leroux T, Wasserstein D, Henry P, et al. Rate of and risk factors for reoperations after open reduction and internal fixation of midshaft clavicle fractures: a population-based study in Ontario, Canada. J Bone Joint Surg Am. 2014;96(13):1119–1125. doi:10.2106/JBJS.M.00607
   PubMed Web of Science ®Google Scholar
• Oh JH, Kim SH, Lee JH, Shin SH, Gong HS. Treatment of distal clavicle fracture: a systematic review of treatment modalities in 425 fractures. Arch Orthop Trauma Surg. 2011;131(4):525–533. doi:10.1007/s00402-010-1196-y
   PubMed Web of Science ®Google Scholar
• Wurm M, Siebenlist S, Zyskowski M, et al. Excellent clinical and radiological outcome following locking compression plate fixation of displaced medial clavicle fractures. BMC Musculoskelet Disord. 2021;22(1):905. doi:10.1186/s12891-021-04775-8
   PubMed Web of Science ®Google Scholar
• Rollo G, Pichierri P, Marsilio A, Filipponi M, Bisaccia M, Meccariello L. The challenge of nonunion after osteosynthesis of the clavicle: is it a biomechanical or infection problem? Clin Cases Miner Bone Metab. 2017;14(3):372–378. doi:10.11138/ccmbm/2017.14.3.372
   PubMedGoogle Scholar
• Martetschläger F, Gaskill TR, Millett PJ. Management of clavicle nonunion and malunion. J Shoulder Elbow Surg. 2013;22(6):862–868. doi:10.1016/j.jse.2013.01.022
   PubMed Web of Science ®Google Scholar
• Stufkens SA, Kloen P. Treatment of midshaft clavicular delayed and non-unions with anteroinferior locking compression plating. Arch Orthop Trauma Surg. 2010;130(2):159–164. doi:10.1007/s00402-009-0864-2
   PubMed Web of Science ®Google Scholar
• Stravinskas M, Horstmann P, Ferguson J, et al. Pharmacokinetics of gentamicin eluted from a regenerating bone graft substitute: in vitro and clinical release studies. Bone Joint Res. 2016;5(9):427–435. doi:10.1302/2046-3758.59.BJR-2016-0108.R1
   PubMed Web of Science ®Google Scholar
• Ferguson J, Athanasou N, Diefenbeck M, McNally M. Radiographic and histological analysis of a synthetic bone graft substitute eluting gentamicin in the treatment of chronic osteomyelitis. J Bone Jt Infect. 2019;4(2):76–84. doi:10.7150/jbji.31592
   PubMedGoogle Scholar
• Amstutz HC, Sew Hoy AL, Clarke IC. UCLA anatomic total shoulder arthroplasty. Clin Orthop Relat Res. 1981;155:7–20. doi:10.1097/00003086-198103000-00002
   PubMed Web of Science ®Google Scholar
• Beaton DE, Wright JG, Katz JN; Upper Extremity Collaborative Group. Development of the QuickDASH: comparison of three item-reduction approaches. J Bone Joint Surg Am. 2005;87(5):1038–1046. doi:10.2106/JBJS.D.02060
   PubMed Web of Science ®Google Scholar
• Ware J Jr, Kosinski M, Keller SD. A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34(3):220–233. doi:10.1097/00005650-199603000-00003
   PubMed Web of Science ®Google Scholar
• Goldberg VM, Powell A, Shaffer JW, Zika J, Bos GD, Heiple KG. Bone grafting: role of histocompatibility in transplantation. J Orthop Res. 1985;3(4):389–404. doi:10.1002/jor.1100030401
   PubMed Web of Science ®Google Scholar
• Choi Y, Yang YH, Kwon YH. Reliability of Goldberg scoring system in the radiographic evaluation of bony union after bone grafting. Clin Orthop Surg. 2021;13(4):549. doi:10.4055/cios19152
   PubMed Web of Science ®Google Scholar
• Aljawadi A, Islam A, Jahangir N, et al. One-stage combined “fix and flap” approach for complex open Gustilo-Anderson IIIB lower limbs fractures: a prospective review of 102 cases. Arch Orthop Trauma Surg. 2021:1–10. doi:10.1007/s00402-020-03392-9
   Web of Science ®Google Scholar
• McNally MA, Ferguson JY, Lau AC, et al. Single-stage treatment of chronic osteomyelitis with a new absorbable, gentamicin-loaded, calcium sulphate/hydroxyapatite biocomposite: a prospective series of 100 cases. Bone Joint J. 2016;98-B(9):1289–1296. doi:10.1302/0301-620X.98B9.38057
   PubMed Web of Science ®Google Scholar
• Freischmidt H, Armbruster J, Reiter G, Grützner PA, Helbig L, Guehring T. Individualized techniques of implant coating with an antibiotic-loaded, hydroxyapatite/calcium sulphate bone graft substitute. Ther Clin Risk Manag. 2020;16:689–694. doi:10.2147/TCRM.S242088
   PubMed Web of Science ®Google Scholar
• Pesch S, Hanschen M, Greve F, et al. Treatment of fracture-related infection of the lower extremity with antibiotic-eluting ceramic bone substitutes: case series of 35 patients and literature review. Infection. 2020;48(3):333–344. doi:10.1007/s15010-020-01418-3
   PubMed Web of Science ®Google Scholar
• Buckup K, Buckup J, Pässler HH. Klinische Tests an Knochen, Gelenken Und Muskeln: Untersuchungen-Zeichen-Phänomene [Clinical Tests on Bones, Joints and Muscles: Examinations-Signs-Phenomena]. Springer; 2012.
   Google Scholar
• Gummesson C, Ward MM, Atroshi I. The shortened disabilities of the arm, shoulder and hand questionnaire (QuickDASH): validity and reliability based on responses within the full-length DASH. BMC Musculoskelet Disord. 2006;7(1):44. doi:10.1186/1471-2474-7-44
   PubMed Web of Science ®Google Scholar
• Nutton RW, McBirnie JM, Phillips C. Treatment of chronic rotator-cuff impingement by arthroscopic subacromial decompression. J Bone Joint Surg Br. 1997;79(1):73–76. doi:10.1302/0301-620X.79B1.0790073
   PubMedGoogle Scholar
• Strada L, Schmidt CS, Rosenkranz M, et al. Factors associated with health-related quality of life in a large national sample of patients receiving opioid substitution treatment in Germany: a cross-sectional study. Subst Abuse Treat Prev Policy. 2019;14(1):1–14. doi:10.1186/s13011-018-0187-9
   PubMed Web of Science ®Google Scholar
• Beirer M, Siebenlist S, Crönlein M, et al. Clinical and radiological outcome following treatment of displaced lateral clavicle fractures using a locking compression plate with lateral extension: a prospective study. BMC Musculoskelet Disord. 2014;15(1):1–9. doi:10.1186/1471-2474-15-380
   PubMed Web of Science ®Google Scholar
• Pecci M, Kreher JB. Clavicle fractures. Am Fam Physician. 2008;77(1):65–70.
   PubMed Web of Science ®Google Scholar
• Ferran NA, Hodgson P, Vannet N, Williams R, Evans RO. Locked intramedullary fixation vs plating for displaced and shortened mid-shaft clavicle fractures: a randomized clinical trial. J Shoulder Elbow Surg. 2010;19(6):783–789. doi:10.1016/j.jse.2010.05.002
   PubMed Web of Science ®Google Scholar
• Böstman O, Manninen M, Pihlajamäki H. Complications of plate fixation in fresh displaced midclavicular fractures. J Trauma. 1997;43(5):778–783. doi:10.1097/00005373-199711000-00008
   PubMedGoogle Scholar
• Wijdicks FJ, Van der Meijden OA, Millett PJ, Verleisdonk EJ, Houwert RM. Systematic review of the complications of plate fixation of clavicle fractures. Arch Orthop Trauma Surg. 2012;132(5):617–625. doi:10.1007/s00402-011-1456-5
   PubMed Web of Science ®Google Scholar
• Martetschläger F, Gaskill TR, Millett PJ. Management of clavicle nonunion and malunion. J Shoulder Elbow Surg. 2013;22(6):862-8.
   Google Scholar
• Schnetzke M, Morbitzer C, Aytac S, et al. Additional bone graft accelerates healing of clavicle non-unions and improves long-term results after 8.9 years: a retrospective study. J Orthop Surg Res. 2015;10(1):1–9. doi:10.1186/s13018-014-0143-y
   PubMed Web of Science ®Google Scholar