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Review

Efficacy versus safety: the dilemma of using novel platelet inhibitors for the treatment of patients with ischemic stroke and coronary artery disease

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Pages 321-329 | Published online: 02 May 2014

References

  • HeuschmannPUDi CarloABejotYEuropean Registers of Stroke (EROS) InvestigatorsIncidence of stroke in Europe at the beginning of the 21st centuryStroke20094051557156319325154
  • NicholsMTownsendNLuengo-FernandezREuropean Cardiovascular Disease Statistics 2012BrusselsEuropean Heart Network and European Society of Cardiology2012 Available from: http://www.escardio.org/about/documents/eu-cardiovascular-disease-statistics-2012.pdfAccessed February 22, 2014
  • RogerVLGoASLloyd-JonesDMHeart disease and stroke statistics – 2012 update: a report from the American Heart AssociationCirculation20121251e2e22022179539
  • DucroqGAmarencoPLabreucheJA history of stroke/ transient ischemic attack indicates high risks of cardiovascular event and hemorrhagic stroke in patients with coronary artery diseaseStroke20131276730738
  • MukherjeeDEagleKAKline-RogersEGRACE InvestigatorsImpact of prior peripheral arterial disease and stroke on outcomes of acute coronary syndromes and effect of evidence-based therapies (from the Global Registry of Acute Coronary Events)Am J Cardiol200710011617599431
  • BhattDLPetersonEDHarringtonRACRUSADE InvestigatorsPrior polyvascular disease: risk factor for adverse ischaemic outcomes in acute coronary syndromesEur Heart J200930101195120219339264
  • BrilakisESHernandezAFDaiDQuality of care for acute coronary syndrome patients with known atherosclerotic disease: results from the Get With the Guidelines ProgramCirculation2009120756056719652090
  • JensenJKMedinaHMNorgaardBLAssociation of ischemic stroke to coronary artery disease using computed tomography coronary angiographyInt J Cardiol2012160317117421543126
  • SubherwalSBachRGChenAYBaseline risk of major bleeding in non-ST-segment-elevation myocardial infarction: the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) bleeding scoreCirculation2009119141873188219332461
  • LiaoJKSecondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?Circulation2007115121615162117389280
  • WiviottSDBraunwaldEMcCabeCHPrasugrel versus clopidogrel in patients with acute coronary syndromesN Eng J Med20073572020012015
  • WallentinLBeckerRCBudajATicagrelor versus clopidogrel in patients with acute coronary syndromesN Engl J Med2009361111045105719717846
  • TricociPHuangZHeldCThrombin-receptor antagonist vorapaxar in acute coronary syndromesN Engl J Med20123661203322077816
  • MorrowDABraunwaldEBonacaMPVorapaxar in the secondary prevention of atherothrombotic eventsN Engl J Med2012366151404141322443427
  • International Stroke Trial Collaborative GroupThe International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19,435 patients with acute ischaemic strokeLancet19973499065156915819174558
  • JauchECSaverJLAdamsHPJrGuidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/ American Stroke AssociationStroke201344387094723370205
  • JohnsonESLanesSFWentworthCE3rdSatterfieldMHAbebeBLDickerLWA meta-regression analysis of the dose–response effect of aspirin on strokeArch Intern Med1999159111248125310371234
  • FurieKLKasnerSEAdamsRJGuidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/ American Stroke AssociationStroke201142122727620966421
  • HerbertJMSaviPP2Y12, a new platelet ADP receptor, target of clopidogrelSemin Vasc Med20033211312215199474
  • SaviPPereilloJMUzabiagaMFIdentification and biological activity of the active metabolite of clopidogrelThromb Haemost200084589189611127873
  • CAPRIE Steering CommitteeA randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)Lancet19963489038132913398918275
  • DienerHCSaccoRLYusufSEffects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active, and placebo-controlled studyLancet Neurol200871087588418757238
  • DienerHCBogousslavskyJBrassLMAspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trialLancet2004364943133133715276392
  • BhattDLFoxKAHackeWClopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic eventsN Engl J Med2006354161706171716531616
  • GUSTO InvestigatorsAn international randomized trial comparing four thrombolytic strategies for acute myocardial infarctionN Engl J Med1993329106736828204123
  • WardlawJMWhat causes lacunar stroke?J Neurol Neurosurg Psychiatry200576561761915834013
  • BenaventeORWhiteCLPearceLThe Secondary Prevention of Small Subcortical Strokes (SPS3) studyInt J Stroke20116216417521371282
  • KennedyJHillMDRyckborstKJEliasziwMDemchukAMBuchanAMFASTER InvestigatorsFast assessment of stroke and transient ischemic attack to prevent early recurrence (FASTER): a randomized controlled pilot trialLancet Neurol200761196196917931979
  • HankeyGJJohnstonSCEatonJDEffect of clopidogrel plus ASA vs ASA early after TIA and ischaemic stroke: a substudy of the CHARISMA trialInt J Stroke2011613921205234
  • WangYWangYZhaoXClopidogrel with aspirin in acute minor stroke or transient ischemic attackN Engl J Med20133691111923803136
  • JohnstonSCEastonJDFarrantMPlatelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and designInt J Stroke20138647948323879752
  • JakubowskiJAWintersKJNaganumaHWallentinLPrasugrel: a novel thienopyridine antiplatelet agent: a review of preclinical and clinical studies and the mechanicistic basis for its distinct antiplatelet profileCardiovasc Drug Rev200725435737418078435
  • AngiolilloDJCapranzanoPPharmacology of emerging novel platelet inhibitorsAm Heart Journal2008156Suppl 2S10S1518657681
  • WiviottSDAntmanEMGibsonCMEvaluation of prasugrel compared with clopidogrel in patients with acute coronary syndromes: design and rationale for the TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet inhibitioN with prasugrel Thrombolysis In Myocardial Infarction 38 (TRITON-TIMI 38)Am Heart J2006152462763516996826
  • RoeMTArmstrongPWFoxKAPrasugrel versus clopidogrel for acute coronary syndromes without revascularizationN Engl J Med2012367141297130922920930
  • US Food and Drug AdministrationCardiovascular and Renal Drug Advisory Committee Briefing Document: Prasugrel for ACSSilver Spring, MDFood and Drug Administration2009 Available from: http://www.fda.gov/ohrms/dockets/ac/09/briefing/2009-4412b1-01-FDA.pdfAccessed December 11, 2013
  • HustedSvan GiezenJTicagrelor: the first reversibly binding oral P2Y12 receptor antagonistCardiovasc Ther200927425927419604248
  • TengRButlerKPharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y12 receptor antagonist, in healthy subjectsEur J Clin Pharmacol201066548749620091161
  • JamesSKStoreyRFKhurmiNSTicagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attackCirculation2012125232914292122572911
  • AngiolilloDJCapodannoDGotoSPlatelet thrombin receptor antagonism and atherothrombosisEur Heart J2010311172819948715
  • MorrowDAAlbertsMJMohrJPEfficacy and safety of vorapaxar in patients with prior ischemic strokeStroke201344369169823396280
  • LimMJEagleKAGoreJMTreating patients with acute coronary syndromes with aggressive antiplatelet therapy (from the Global Registry of Acute Coronary Events)Am J Cardiol200596791792116188516
  • PalmeriniTBiondi-ZoccaiGDella RivaDStent thrombosis with drug eluting stents: is the paradigm shifting?J Am Coll Cardiol201362211915192124036025
  • KolandaiveluKSwaminathanRGibsonWJStent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer–drug coatingsCirculation2011123131400140921422389
  • PalmeriniTBiondi-ZoccaiGDella RivaDStent thrombosis with drug-eluting stent and bare-metal stents: evidence from a comprehensive network meta-analysisLancet201237998241393140222445239
  • FlynnRWMacDonaldTMMurrayGDMacWalterRSDoneyASPrescribing antiplatelet medicine and subsequent events after intracerebral hemorrhageStroke201041112606261120947854
  • ViswanathanARakichSMEngelCAntiplatelet use after intracerebral hemorrhageNeurology200666220620916434655