207
Views
1
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

The Value of Anticoagulation Management Combining Telemedicine and Self-Testing in Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials

ORCID Icon, , &
Pages 279-290 | Received 01 Nov 2022, Accepted 02 Mar 2023, Published online: 14 Mar 2023

References

  • Coffey S, Roberts-Thomson R, Brown A, et al. Global epidemiology of valvular heart disease. Nat Rev Cardiol. 2021;18(12):853–864. doi:10.1038/s41569-021-00570-z
  • Benjamin EJ, Muntner P, Alonso A, et al. Heart disease and stroke statistics-2019 update: a report from the American Heart Association. Circulation. 2019;139:e56–528.
  • Steinberg BA, Hellkamp AS, Lokhnygina Y, et al. Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial. Eur Heart J. 2015;36:288–296.
  • Schnabel RB, Yin X, Gona P, et al. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, mortality in the Framingham Heart Study: a cohort study. Lancet. 2015;386:154–162.
  • Nishimura RA, Otto CM, Bonow RO, et al. 2017AHA/ACC Focused update of the 2014 AHA/ACC Guideline for the Management of Patients with Valvular Heart Disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017;135:e1159–e1195.
  • Goldhaber SZ, Bounameaux H. Embolism in pulmonary embolism. Lancet. 2012;379:1835–1846.
  • Li B, Liu R, Wang C, et al. Impact of genetic and clinical factors on warfarin therapy in patients early after heart valve replacement surgery. Eur J Clin Pharmacol. 2019;75:1685–1693.
  • Zhang H, Dong Y, Ao X, et al. Optimal oral anticoagulant therapy in Chinese patients with mechanical heart valves. Eur J Pharm Sci. 2020;144:105–202.
  • Lee MTM, Klein TE. Pharmacogenetics of warfarin: challenges and opportunities. J Hum Genet. 2013;58:334–338.
  • Zhang J, Lu Y. Biocomputing for portable, resettable, and quantitative point-of-care diagnostics: making the glucose meter a logic-gate responsive device for measuring many clinically relevant targets. Angew Chem Int Ed Engl. 2018;57:9702–9706.
  • Soffe R, Nock V, Chase JG. Towards point-of-care insulin detection. ACS Sens. 2019;4:3–19.
  • Peterson LF, Gooding JJ. The application of personal glucose meters as universal point-of-care diagnostic tools. Biosens Bioelectron. 2020;148:111835.
  • Deeken F, Rezo A, Hinz M, Discher R, Rapp MA. Evaluation of technology-based interventions for informal caregivers of patients with dementia - A meta-analysis of randomized controlled trials. Am J Geriatr Psychiatr. 2019;27:426–445.
  • Nichol MB, Knight TK, Dow T, et al. Quality of anticoagulation monitoring in nonvalvular atrial fibrillation patients: comparison of anticoagulation clinic versus usual care. Ann Pharmacother. 2008;42:62–70.
  • Viswanathan M, Golin CE, Jones CD, et al. Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review. Ann Intern Med. 2012;157:785–795.
  • Barcellona D, Fenu L, Marongiu F. Point-of-care testing INR: an overview. Clin Chem Lab Med. 2017;55:800–805.
  • Tait RC, Hung A, Gardner RS. Performance of the LumiraDx platform INR test in an anticoagulation clinic point-of-care setting compared with an established laboratory reference method. Clin Appl Thromb Hemost. 2019;25:1076029619890423.
  • Sobieraj-Teague M, Daniel D, Farrelly B, Coghlan D, Gallus A. Accuracy and clinical usefulness of the CoaguChek S and XS Point of Care devices when starting warfarin in a hospital outreach setting. Thromb Res. 2009;123:909–913.
  • Nelson R. Telemedicine and telehealth: the potential to improve rural access to care. Am J Nurs. 2017;117:17–18.
  • Kane JM. Evidence-based interventions in health care. Epidemiol Psychiatr Sci. 2014;23:323–326.
  • Zeolla MM, Brodeur MR, Dominelli A, Haines ST, Allie ND. Development and validation of an instrument to determine patient knowledge: the oral Anticoagulation Knowledge Test. Ann Pharmacother. 2006;40:633–638.
  • Tuckson RV, Edmunds M, Hodgkins ML. Telehealth. N Engl J Med. 2017;377:1585–1592.
  • Rosendaal FR, Cannegieter SC, van der Meer FJ, Briët E. A method to determine the optimal intensity of oral anticoagulant therapy. Thromb Haemost. 1993;69(3):236–239.
  • Vestergaard AS, Skjøth F, Larsen TB, Ehlers LH. The importance of mean time in therapeutic range for complication rates in warfarin therapy of patients with atrial fibrillation: a systematic review and meta-regression analysis. PLoS One. 2017;12(11):e0188482.
  • Kirchhof P, Benussi S, Kotecha D, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J. 2016;37(38):2893–2962. doi:10.1093/eurheartj/ehw210
  • Lip GYH, Banerjee A, Boriani G, et al. Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report. Chest. 2018;154(5):1121–1201. doi:10.1016/j.chest.2018.07.040
  • Fitzmaurice DA, Murray ET, Gee KM, Allan TF, Hobbs FDR. A randomised controlled trial of patient self-management of oral anticoagulation treatment compared with primary care management. J Clin Pathol. 2002;55:845–849.
  • Staresinic AG, Sorkness CA, Goodman BM. Comparison of outcomes using 2 delivery models of anticoagulation care. Arch Intern Med. 2006;166:997–1002.
  • Lalonde L, Martineau J, Blais N, et al. Is long-term pharmacist-managed anticoagulation service efficient? A pragmatic randomized controlled trial. Am Heart J. 2008;156:148–154.
  • Schillig J, Kaatz S, Hudson M, Krol GD, Szandzik EG, Kalus JS. Clinical and safety impact of an inpatient pharmacist-directed anticoagulation service. J Hosp Med. 2011;6:322–328.
  • Liang JB, Lao CK, Tian L, et al. Impact of a pharmacist-led education and follow-up service on anticoagulation control and safety outcomes of a tertiary hospital in China: a randomised controlled trial. Int J Pharm Pract. 2020;28:97–106.
  • van Zyl M, Wysokinski WE, Jaeger TM, Casanegra AI, Gersh BJ. In-home compared with in-clinic warfarin therapy monitoring in mechanical heart valves: a population-based study. Mayo Clin Proc Innov Qual Outcomes. 2020;4:511–520.
  • Lee M, Wang M, Liu J, Holbrook A. Do telehealth interventions improve oral anticoagulation management? A systematic review and meta-analysis. J Thromb Thrombolysis. 2018;45:325–336.
  • (EPOC), Cochrane EPOC Data Collection Form. EPOC Resources for review authors; 2013. Available from http://epoc.cochrane.org/epoc-resources-review-authors. Accessed March 6, 2023.
  • Ryan F, Byrne S, O’Shea S. Randomized controlled trial of supervised patient self-testing of warfarin therapy using an internet-based expert system. J Thromb Haemost. 2009;7:1284–1290.
  • Gallagher J, McCarthy S, Woods N, Ryan F, O’Shea S, Byrne S. Economic evaluation of a randomized controlled trial of pharmacist-supervised patient self-testing of warfarin therapy. J Clin Pharm Ther. 2015;40(1):14–19.
  • Christensen H, Lauterlein JJ, Sørensen PD, Petersen ER, Madsen JS, Brandslund I. Home management of oral anticoagulation via telemedicine versus conventional hospital-based treatment. Telemed J E Health. 2011;17:169–176.
  • Beyth RJ, Quinn L, Landefeld CS. A multicomponent intervention to prevent major bleeding complications in older patients receiving warfarin. A randomized, controlled trial. Ann Intern Med. 2000;133:687–695.
  • Verret L, Couturier J, Rozon A, et al. Impact of a pharmacist-led warfarin self-management program on quality of life and anticoagulation control: a randomized trial. Pharmacotherapy. 2012;32:871–879.
  • Chan FW, Wong RS, Lau WH, Chan TY, Cheng G, You JH. Management of Chinese patients on warfarin therapy in two models of anticoagulation service - A prospective randomized trial. Br J Clin Pharmacol. 2006;62(5):601–609. doi:10.1111/j.1365-2125.2006.02693.x
  • Soliman HMA, van Eekelen E, van Agt T, van Straten AH. Self-management program improves anticoagulation control and quality of life: a prospective randomized study. Eur J Cardiothorac Surg. 2009;35:265–269.
  • Matchar DB, Jacobson A, Dolor R, et al. Effect of home testing on international normalized ratio in clinical events. N Engl J Med. 2010;363:1608–1620.
  • Khan TI, Kamali F, Kesteven P, Avery P, Wynne H. The value of education and self-monitoring in the management of warfarin therapy in older patients with unstable control of anticoagulation. Br J Haematol. 2004;126:557–564.
  • Brasen CL, Madsen JS, Parkner T, Brandslund I. Home management of warfarin treatment through a real-time supervised telemedicine solution: a randomized controlled trial. Telemed J E Health. 2019;25:109–115.
  • Cao H, Wu J, Zhang J. Outcomes of warfarin therapy managed by pharmacists via hospital anticoagulation clinic versus online. Int J Clin Pharm. 2018;40:1072–1077.
  • Vinding NE, Bonde AN, Rørth R, et al. The importance of time in therapeutic range in switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulants in atrial fibrillation. Europace. 2019;21(4):572–580.
  • Cao H, Jiang S, Lv M, et al. Effectiveness of the Alfalfa app in warfarin therapy management for patients undergoing venous thrombosis prevention and treatment: cohort study. JMIR Mhealth uHealth. 2021;9:e23332.
  • Zandi S, Imani B, Gholamreza S. Self-care training and informational support of patients with a mechanical heart valve on the international normalized ratio and bleeding complications. Kardiochir Torakochirurgia Pol. 2021;18:80–86.
  • Xia X, Wu J, Zhang J. The effect of online versus hospital warfarin management on patient outcomes: a systematic review and meta-analysis. Int J Clin Pharm. 2018;40:1420–1429.
  • Dai H, Zheng C, Lin C, et al. Technology-based interventions in oral anticoagulation management: meta-analysis of randomized controlled trials. J Med Internet Res. 2020;22(7):e18386. doi:10.2196/18386
  • Cryder BT, Felczak MA, Darkwa A, Patel H, Janociak JD, Rihani R. Transition of stable patients from traditional anticoagulation clinic services to telephonic management. Int J Clin Pharm. 2017;39:569–572.
  • Craig JA, Chaplin S, Jenks M. Warfarin monitoring economic evaluation of point of care self-monitoring compared to clinic settings. J Med Econ. 2014;17:184–190.
  • Zhu Z, Li C, Shen J, et al. New internet-based warfarin anticoagulation management approach after mechanical heart valve replacement: prospective, multicenter, randomized controlled trial. J Med Internet Res. 2021;23:E29529.
  • Heneghan C, Ward A, Perera R, et al. Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data. Lancet. 2012;379:322–334.
  • Samsa GP, Matchar DB. Relationship between test frequency and outcomes of anticoagulation: a literature review and commentary with implications for the design of randomized trials of patient self-management. J Biomed Eng. 2000;9:283–292.
  • Jiang S, He Q, Yan J, et al. Evaluation of a pharmacist-led remote warfarin management model using a smartphone application (Yixing) in improving patients’ knowledge and outcomes of anticoagulation therapy. Front Pharmacol. 2021;12:677943.
  • O’Shea SI, Arcasoy MO, Samsa G, et al. Direct-to-patient expert system and home INR monitoring improves control of oral anticoagulation. J Thromb Thrombolysis. 2008;26(1):14–21.
  • Alhmoud EN. Drive-up INR testing and phone-based consultations service during COVID-19 pandemic in a pharmacist-lead anticoagulation clinic in Qatar: monitoring, clinical, resource utilization, and patient-oriented outcomes. J Am Coll Clin Pharm. 2021. doi:10.1002/jac5.1469
  • Yan CH, Naveed M, Alobaidi A, Kopfman M, Nutescu EA, Sharp LK. Association between transportation barriers and anticoagulation control among an inner-city, low-income population: a prospective observational cohort study. Res Pract Thromb Haemost. 2021;5(7):e12605. doi:10.1002/rth2.12605
  • Bussey HI. Transforming oral anticoagulation by combining international normalized ratio (INR) self testing and online automated management. J Thromb Thrombolysis. 2011;31:265–274.
  • Yamamura K, Yano K, Hirooka Y, Hirashiki A, Murohara T, Yamada K. A successful case of a patient undergoing warfarin and S-1 therapy using internet-based control of home-measured PT-INR. Yakugaku Zasshi. 2015;135(7):925–927.
  • Lopez-Villegas A, Bautista-Mesa RJ, Baena-Lopez MA, et al. Economic impact and cost savings of teledermatology units compared to conventional monitoring at hospitals in southern Spain. J Telemed Telecare. 2022;28(6):436–444. doi:10.1177/1357633X20942044