140
Views
6
CrossRef citations to date
0
Altmetric
Review

Personalized therapeutics for levofloxacin: a focus on pharmacokinetic concerns

, , , &
Pages 217-227 | Published online: 27 Mar 2014

References

  • International Pharmaceutical FederationTowards a future vision for complex patients Available from: http://www.fip.org/dublin2013/Dublin/2041/ProGramme/Accessed December 4, 2013
  • MorelloCMHirschJDLeeKCNavigating complex patients using an innovative tool: the MTM Spider WebJ Am Pharm Assoc (2003)20135353053824030131
  • Joint Commission InternationalJCI accreditation standards for hospitalsOak Brook, IL, USAJoint Commission International2010 Available from: http://www.jointcommissioninternational.org/common/pdfs/jcia/IAS400_Standards_Lists_Only.pdfAccessed March 20, 2013
  • LiWZhouQPatient diagnosis on electronic prescription orders: a key element for appropriateness review by pharmacistsRes Social Adm Pharm2013949349423890197
  • ZhuLLZhouQIntervention for improving the appropriateness of physician orders for oral medications in geriatric VIP patients during the journey to JCI accreditationTher Clin Risk Manag2013927327523761971
  • McGregorJCAllenGPBeardenDTLevofloxacin in the treatment of complicated urinary tract infections and acute pyelonephritisTher Clin Risk Manag2008484385319209267
  • GiordanoPWeberKGesinGKubertJSkin and skin structure infections: treatment with newer generation fluoroquinolonesTher Clin Risk Manag2007330931718360639
  • PrajapatiAGangulyBAppropriateness of drug dose and frequency in patients with renal dysfunction in a tertiary care hospital: a cross-sectional study20135136140
  • NicolauDPPredicting antibacterial response from pharmacodynamic and pharmacokinetic profilesInfection200129Suppl 2111511785851
  • LabrecheMJFreiCRDeclining susceptibilities of Gram-negative bacteria to the fluoroquinolones: effects on pharmacokinetics, pharmacodynamics, and clinical outcomesAm J Health Syst Pharm2012691863187023111670
  • DrusanoGLPrestonSLFowlerCCorradoMWeisingerBKahnJRelationship between fluoroquinolone area under the curve: minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumoniaJ Infect Dis20041891590159715116294
  • DefifeRScheetzMHFeinglassJMPostelnickMJScarsiKKEffect of differences in MIC values on clinical outcomes in patients with bloodstream infections caused by Gram-negative organisms treated with levofloxacinAntimicrob Agents Chemother2009531074107919075047
  • AndersonVRPerryCMLevofloxacin: a review of its use as a high-dose, short-course treatment for bacterial infectionDrugs20086853556518318569
  • NoreddinAMElkhatibWFCunnionKMZhanelGGCumulative clinical experience from over a decade of use of levofloxacin in community-acquired pneumonia: critical appraisal and role in therapyDrug Healthc Patient Saf20113596822046107
  • CookAMMartinCAdamsVRMoreheadRSPharmacokinetics of intravenous levofloxacin administered at 750 milligrams in obese adultsAntimicrob Agents Chemother2011553240324321576432
  • PaiMPAllenSEAmsdenGWAltered steady state pharmacokinetics of levofloxacin in adult cystic fibrosis patients receiving calcium carbonateJ Cyst Fibros2006515315716481224
  • OverholserBRKaysMBLagvankarSGoldmanMMuellerBASowinskiKMPharmacokinetics of intravenously administered levofloxacin in men and womenPharmacotherapy2005251310131816185174
  • ChienSWellsTGBlumerJLLevofloxacin pharmacokinetics in childrenJ Clin Pharmacol20054515316015647407
  • NoreddinAMHobanDJZhanelGGComparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoniaeInt J Antimicrob Agents20052612012516046101
  • PeaFDi QualECusenzaABrolloLBaldassarreMFurlanutMPharmacokinetics and pharmacodynamics of intravenous levofloxacin in patients with early-onset ventilator-associated pneumoniaClin Pharmacokinet20034258959812793843
  • PrestonSLDrusanoGLBermanALLevofloxacin population pharmacokinetics and creation of a demographic model for prediction of individual drug clearance in patients with serious community-acquired infectionAntimicrob Agents Chemother199842109811049593134
  • JansonBThurskyKDosing of antibiotics in obesityCurr Opin Infect Dis20122563464923041773
  • LuqueSGrauSValleMColinoCIFerrerALevofloxacin weight-adjusted dosing and pharmacokinetic disposition in a morbidly obese patientJ Antimicrob Chemother2011661653165421474480
  • KeesMGWeberSKeesFHorbachTPharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patientsJ Antimicrob Chemother2011662330233521729931
  • ReyETréluyerJMPonsGDrug disposition in cystic fibrosisClin Pharmacokinet1998353133299812180
  • HurleyMSmythAFluoroquinolones in the treatment of bronchopulmonary disease in cystic fibrosisTher Adv Respir Dis2012636337322968160
  • LeeCKBoyleMPDiener-WestMBrass-ErnstLNoscheseMZeitlinPLLevofloxacin pharmacokinetics in adult cystic fibrosisChest200713179680217356095
  • GellerDEFlumePAStaabDFischerRLoutitJSConradDJMpex 204 Study GroupLevofloxacin inhalation solution (MP-376) in patients with cystic fibrosis with Pseudomonas aeruginosaAm J Respir Crit Care Med20111831510151621471106
  • AlmeidaSFilipeAAlmeidaAWongHCaparrósNTanguayMComparative bioavailability of two formulations of levofloxacin and effect of sex on bioequivalence analysis. Data from a randomised, 2 × 2 crossover trial in healthy volunteersArzneimittelforschung20055541441916080281
  • ChienSCChowATNatarajanJAbsence of age and gender effects on the pharmacokinetics of a single 500-milligram oral dose of levofloxacin in healthy subjectsAntimicrob Agents Chemother199741156215659210685
  • Food and Drug AdministrationLevaquin medication guide Available from: http://www.fda.gov/downloads/Drugs/.../UCM133684.pdfAccessed December 4, 2013
  • BaileyAMWeantKABakerSNPrevalence and risk factor analysis of resistant Escherichia coli urinary tract infections in the emergency departmentPharm Pract (Granada)2013119610124155856
  • TanigawaraYNomuraHKagimotoNOkumuraKHoriRPremarketing population pharmacokinetic study of levofloxacin in normal subjects and patients with infectious diseasesBiol Pharm Bull1995183153207742805
  • TayabZRHochhausGKaufmannSJägerDBarthJDo intensive care patients need an individualized dosing regimen for levofloxacin?Int J Clin Pharmacol Ther20064426226916800098
  • RebuckJAFishDNAbrahamEPharmacokinetics of intravenous and oral levofloxacin in critically ill adults in a medical intensive care unitPharmacotherapy2002221216122512389872
  • Sánchez NavarroAColino GandarillasCIAlvarez LermaFMenachoYADomínguez-GilAPharmacokinetics and pharmacodynamics of levofloxacin in intensive care patientsClin Pharmacokinet20054462763515910010
  • ChienSCRoggeMCGisclonLGPharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous dosesAntimicrob Agents Chemother199741225622609333057
  • YenYHChenHYWuan-JinLLinYMShenWCChengKJClinical and economic impact of a pharmacist-managed iv-to-po conversion service for levofloxacin in TaiwanInt J Clin Pharmacol Ther20125013614122257579
  • DeguchiTSeikeKYasudaMMatsumotoTEvaluation by Monte Carlo simulation of levofloxacin dosing for complicated urinary tract infections caused by Escherichia coli or Pseudomonas aeruginosaJ Infect Chemother20111772673021409530
  • LeeLJHafkinBLeeIDHohJDixREffects of food and sucralfate on a single oral dose of 500 milligrams of levofloxacin in healthy subjectsAntimicrob Agents Chemother199741219622009333047
  • AmsdenGWWhitakerAMJohnsonPWLack of bioequivalence of levofloxacin when coadministered with a mineral-fortified breakfast of juice and cerealJ Clin Pharmacol20034399099512971031
  • WallaceAWVictoryJMAmsdenGWLack of bioequivalence when levofloxacin and calcium-fortified orange juice are coadministered to healthy volunteersJ Clin Pharmacol20034353954412751275
  • AltintasROguzFBeyturAEdizCGunesAOzerAComparison of results after flouroquinolones and combination therapies in type IIIA chronic prostatitisActas Urol Esp20133761962423768504
  • QinGDXiaoMZZhouYDTamsulosin alters levofloxacin pharmacokinetics in prostates derived from rats with acute bacterial prostatitisAsian J Androl20131525426023353720
  • CohenKALautenbachEWeinerMGSynnestvedtMGasinkLBCoadministration of oral levofloxacin with agents that impair absorption: impact on antibiotic resistanceInfect Control Hosp Epidemiol20082997597718808343
  • VadlamudiRSSmalliganRDIsmailHMInteraction between warfarin and levofloxacin: case seriesSouth Med J200710072072417639754
  • MoffettBSKimSBomgaarsLRReadmissions for warfarin-related bleeding in pediatric patients after hospital dischargePediatr Blood Cancer2013601503150623606286
  • Mercadal OrfilaGGracia GarcíaBLeiva BadosaEPerayre BadíaMReynaldo MartínezCJodar MasanésRRetrospective assessment of potential interaction between levofloxacin and warfarinPharm World Sci20093122422919067226
  • GhaswallaPKHarpeSETassoneDSlattumPWWarfarin-antibiotic interactions in older adults of an outpatient anticoagulation clinicAm J Geriatr Pharmacother20121035236023089199
  • ClarkNPDelateTRiggsCSWarfarin interactions with antibiotics in the ambulatory care settingJAMA Intern Med201417440941624445404
  • DooseDRWalkerSAChienSCWilliamsRRNayakRKLevofloxacin does not alter cyclosporine dispositionJ Clin Pharmacol19983890939597565
  • FedericoSCarranoRCaponeDGentileAPalmieroGBasileVPharmacokinetic interaction between levofloxacin and ciclosporin or tacrolimus in kidney transplant recipients: ciclosporin, tacrolimus and levofloxacin in renal transplantationClin Pharmacokinet20064516917516485913
  • MulgaonkarAVenitzJSweetDHFluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transportersExpert Opin Drug Metab Toxicol2012855356922435536
  • MaedaTTakahashiKOhtsuNIdentification of influx transporter for the quinolone antibacterial agent levofloxacinMol Pharm20074859417274666
  • NaruhashiKTamaiIInoueNActive intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoproteinJ Pharm Pharmacol20015369970911370709
  • ItoTYanoITanakaKInuiKITransport of quinolone antibacterial drugs by human P-glycoprotein expressed in a kidney epithelial cell line, LLC-PK1J Pharmacol Exp Ther19972829559609262363
  • MulgaonkarAVenitzJGründemannDSweetDHHuman organic cation transporters 1 (SLC22A1), 2 (SLC22A2), and 3 (SLC22A3) as disposition pathways for fluoroquinolone antimicrobialsAntimicrob Agents Chemother2013572705271123545524
  • OhtaKYImamuraYOkudairaNAtsumiRInoueKYuasaHFunctional characterization of multidrug and toxin extrusion protein 1 as a facilitative transporter for fluoroquinolonesJ Pharmacol Exp Ther200932862863419004926
  • FrankeRMScherkenbachLASparreboomAPharmacogenetics of the organic anion transporting polypeptide 1A2Pharmacogenomics20091033934419290786
  • GongIYKimRBImpact of genetic variation in OATP transporters to drug disposition and responseDrug Metab Pharmacokinet20132841823047721
  • ZhouQRuanZRYuanHXuDHZengSABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c> A are determinants of inter-subject variability in rosuvastatin pharmacokineticsPharmazie20136812913423469685
  • ChristensenMMPedersenRSStageTBA gene-gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metforminPharmacogenet Genomics20132352653423873119