References
- NavariRMManagement of chemotherapy-induced nausea and vomitingDrugs20137324926223404093
- GrunbergSMSlusherBRugoHSEmerging treatments in chemotherapy-induced nausea and vomitingClin Adv Hematol Oncol2013112 Suppl 111823598819
- RojasCSlusherBSPharmacological mechanisms of 5-HT3 and tachykinin NK1 receptor antagonism to prevent chemotherapy-induced nausea and vomitingEur J Pharmacol20126841–31722425650
- PopovicMWarrDGDeangelisCEfficacy and safety of palonosetron for the prophylaxis of chemotherapy-induced nausea and vomiting (CINV): a systematic review and meta-analysis of randomized controlled trialsSupport Care Cancer20142261685169724590374
- GaoHFLiangYZhouNNZhangDSWuHYAprepitant plus palonosetron and dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients receiving multiple-day cisplatin chemotherapyIntern Med J2013431737622141732
- RojasCRajeMTsukamotoTSlusherBSMolecular mechanisms of 5-HT3 and NK1 receptor antagonists in prevention of emesisEur J Pharmocol20147222637
- AzizFNeurokinin-1 receptor antagonists for chemotherapy-induced nausea and vomitingAnn Palliat Med20121213013625841473
- NavariRMRole of neurokinin-1 receptor antagonists in chemotherapy-induced emesis: summary of clinical trialsCancer Invest200422456957615565815
- Di RenzoNMontaniniAManninaDSingle-dose palonosetron for prevention of chemotherapy-induced nausea and vomiting in patients with aggressive non-Hodgkin’s lymphoma receiving moderately emetogenic chemotherapy containing steroids: results of a phase II study from the Gruppo Italiano per lo Studio dei Linfomi (GISL)Support Care Cancer2011191505151020694798
- Product Monograph. Aloxi®Missisauga, ONEisai Limited2012
- RojasCLiYZhangJThe antiemetic 5-HT3 receptor antagonist Palonosetron inhibits substance P-mediated responses in vitro and in vivoJ Pharmacol Exp Ther2010335236236820724484
- StoltzRCyongJCShahAParisiSPharmacokinetic and safety evaluation of palonosetron, a 5-hydroxytryptamine-3 receptor antagonist, in U.S. and Japanese healthy subjectsJ Clin Pharmacol200444552053115102873
- EisenbergPMackintoshFRRitchPCornettPAMacciocchiAEfficacy, safety and pharmacokinetics of palonosetron in patients receiving highly emetogenic cisplatin-based chemotherapy: a dose-ranging clinical studyAnn Oncol200415233033714760130
- IkariYOgataKNakashimaYSafety and pharmacokinetic evaluation of repeated intravenous administration of palonosetron 0.75 mg in patients receiving highly or moderately emetogenic chemotherapySupport Care Cancer20142271959196424590375
- ShahADeGrootTApseloffGPharmacokinetic evaluation and safety profile of a 15-minute versus 30-second infusion of palonosetron in healthy subjectsJ Clin Pharmacol200646101139114516988202
- HuntTLGallagherSCCullenMTJrShahAKEvaluation of safety and pharmacokinetics of consecutive multiple-day dosing of palonosetron in healthy subjectsJ Clin Pharmacol200545558959615831783
- SadabaBdel BarrioACampaneroMARandomized pharmacokinetic study comparing subcutaneous and intravenous palonosetron in cancer patients treated with platinum based chemotherapyPLoS One201492e8974724587006
- HeskethPJMorrowGKomorowskiAWAhmedRCoxDEfficacy and safety of palonosetron as salvage treatment in the prevention of chemotherapy-induced nausea and vomiting in patients receiving low emetogenic chemotherapy (LEC)Support Care Cancer20122012633267722733373
- BocciaRGrunbergSFranco-GonzalesEEfficacy of oral palonosetron compared to intravenous palonosetron for the prevention of chemotherapy-induced nausea and vomiting associated with moderately emetogenic chemotherapy: a phase 3 trialSupport Care Cancer2013211453146023354552
- EisenbergPFigueroa-VadilloJZamoraRImproved prevention of moderately emetogenic chemotherapy-induced nausea and vomiting with palonosetron, a pharmacologically novel 5-HT3 receptor antagonist: results of a phase III, single-dose trial versus dolasetronCancer200398112473248214635083
- GrallaRLichinitserMVan Der VegtSPalonosetron improves prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetronAnn Oncol200314101570157714504060
- ChoiBSBorsaruGPBallinariGVoisinDDi RenzoNMulticenter phase IV study of palonosetron in the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients with non-Hodgkin lymphomas undergoing repeated cycles of moderately emetogenic chemotherapyLeuk Lymphoma201455354455023772665
- MattiuzziGNCortesJEBlambleDADaily palonosetron is superior to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting in patients with acute myelogenous leukemiaCancer2010116245659566621218459
- DongXHuangJCaoRLiuLPalonosetron for prevention of acute and delayed nausea and vomiting in non-small-cell lung carcinoma patientsMed Oncol2011281425142920602263
- TianWWangZZhouJRandomized, double-blind, crossover study of palonosetron compared with granisetron for the prevention of chemotherapy-induced nausea and vomiting in a Chinese populationMed Oncol201128717820049561
- MaemondoMMasudaNSekineIA phase II study of palonosetron combined with dexamethasone to prevent nausea and vomiting induced by highly emetogenic chemotherapyAnn Oncol200920111860186619561037
- MassaEAstaraGMadedduCPalonosetron plus dexamethasone effectively prevents acute and delayed chemotherapy-induced nausea and vomiting following highly or moderately emetogenic chemotherapy in pre-treated patients who have failed to respond to a previous antiemetic treatment: comparison between elderly and non-elderly patient responseCrit Rev Oncol Hematol2009701839118723369
- AaproMFabiANolèFDouble-blind, randomized, controlled study of the efficacy and tolerability of palonosetron plus dexamethasone for 1 day with or without dexamethasone on days 2 and 3 in the prevention of nausea and vomiting induced by moderately emetogenic chemotherapyAnn Oncol20102151083108820080830
- CelioLFrustaciSDenaroAPalonosetron in combination with 1-day versus 3-day dexamethasone for prevention of nausea and vomiting following moderately emetogenic chemotherapy: a randomized, multicenter, phase III trialSupport Care Cancer20111981217122520574663
- BrugnatelliSGattoniEGrassoDRossettiFPerroneTDanovaMSingle-dose palonosetron and dexamethasone in preventing nausea and vomiting induced by moderately emetogenic chemotherapy in breast and colorectal cancer patientsTumori201197336236621789017
- RozziANardoniCCoronaMPalonosetron for the prevention of chemotherapy-induced nausea and vomiting in glioblastoma patients treated with temozolomide: a phase II studySupport Care Cancer201119569770120467757
- LorussoVGiampagliaMPetrucelliLSaracinoVPerroneTGnoniAAntiemetic efficacy of single-dose palonosetron and dexamethasone in patients receiving multiple cycles of multiple day-based chemotherapySupport Care Cancer201220123241324622534864
- AogiKSakaiHYoshizawaHA phase III open-label study to assess safety and efficacy of palonosetron for preventing chemotherapy-induced nausea and vomiting (CINV) in repeated cycles of emetogenic chemotherapySupport Care Cancer20122071507151421808994
- LorussoVSpedicatoAPetrucelliLSaracinoVGiampagliaMPerroneTSingle dose of palonosetron plus dexamethasone to control nausea, vomiting and to warrant an adequate food intake in patients treated with highly emetogenic chemotherapy (HEC). Preliminary resultsSupport Care Cancer200917121469147319294429
- YavasCDoganUYavasGArazMAtaOYAcute effect of palonosetron on electrocardiographic parameters in cancer patients: a prospective studySupport Care Cancer201220102343234722170340
- DoganUYavasGTekinalpMYavasCAtaOYOzdemirKEvaluation of the acute effect of palonosetron on transmural dispersion of myocardial repolarizationEur Rev Med Pharmacol Sci201216446246822696873
- LongoFMansuetoGLapadulaVPalonosetron plus 3-day aprepitant and dexamethasone to prevent nausea and vomiting in patients receiving highly emetogenic chemotherapySupport Care Cancer20111981159116420552375
- GroteTHajdenbergJCartmellAFergusonSGinkelACharuVCombination therapy for chemotherapy-induced nausea and vomiting in patients receiving moderately emetogenic chemotherapy: palonosetron, dexamethasone, and aprepitantJ Support Oncol20064840340817004515
- HeskethPJSanz-AltamiraPAprepitant, dexamethasone, and palonosetron in the prevention of doxorubicin/cyclophosphamide-induced nausea and vomitingSupport Care Cancer201220365365622089429
- GrunbergSMDuganMMussHEffectiveness of a single-day three-drug regimen of dexamethasone, palonosetron, and aprepitant for the prevention of acute and delayed nausea and vomiting caused by moderately emetogenic chemotherapySupport Care Cancer200917558959419037667
- KimKILeeDEChoIEffectiveness of palonosetron versus other serotonin 5-HT3 receptor antagonists in triple antiemetic regimens during multiday highly emetogenic chemotherapyAnn Pharmacother201246121637164423170032
- AaproMRugoHRossiGA randomized phase III study evaluating the efficacy and safety of NEPA, a fixed-dose combination of netupitant and palonosetron, for prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapyAnn Oncol20142571328133324603643
- HeskethPJRossiGRizziGEfficacy and safety of NEPA, an oral combination of netupitant and palonosetron, for prevention of chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy: a randomized dose-ranging pivotal studyAnn Oncol20142571340134624608196