Diagnosis and management of xerostomia and hyposalivation

References

• HopcraftMSTanCXerostomia: an update for cliniciansAust Dent J2010553238244 quiz 35320887509
   PubMed Web of Science ®Google Scholar
• van der PuttenGJBrandHSScholsJMde BaatCThe diagnostic suitability of a xerostomia questionnaire and the association between xerostomia, hyposalivation and medication use in a group of nursing home residentsClin Oral Investig2011152185192
   PubMed Web of Science ®Google Scholar
• FoxPCvan der VenPFSoniesBCWeiffenbachJMBaumBJXerostomia: evaluation of a symptom with increasing significanceJ Am Dent Assoc198511045195253858368
   PubMed Web of Science ®Google Scholar
• HumphreySPWilliamsonRTA review of saliva: normal composition, flow, and functionJ Prosthet Dent200185216216911208206
   PubMed Web of Science ®Google Scholar
• PedersenAMBardowAJensenSBNauntofteBSaliva and gastrointestinal functions of taste, mastication, swallowing and digestionOral Dis20028311712912108756
   PubMed Web of Science ®Google Scholar
• HeintzeUBirkhedDBjörnHSecretion rate and buffer effect of resting and stimulated whole saliva as a function of age and sexSwed Dent J1983762272386583873
   PubMedGoogle Scholar
• SreebnyLMVissinkADry Mouth: the malevolent symptom A clinical guideAmesWiley-Blackwell2010
   Google Scholar
• DawesCHow much saliva is enough for avoidance of xerostomia?Caries Res200438323624015153694
   PubMed Web of Science ®Google Scholar
• CassolatoSFTurnbullRSXerostomia: clinical aspects and treatmentGerodontology2003202647714697016
   PubMedGoogle Scholar
• VillaAPolimeniAStrohmengerLCicciùDGherloneEAbatiSDental patients’ self-reports of xerostomia and associated risk factorsJ Am Dent Assoc2011142781181621719803
   PubMed Web of Science ®Google Scholar
• EkströmJKhosravaniNCastagnolaMMessanaISaliva and the control of its secretionEkbergODysphagia: Diagnosis and TreatmentBerlinSpringer-Verlag20121947
   Google Scholar
• ThomsonWMIssues in the epidemiological investigation of dry mouthGerodontology2005222657615934347
   PubMedGoogle Scholar
• BergdahlMBergdahlJLow unstimulated salivary flow and subjective oral dryness: association with medication, anxiety, depression, and stressJ Dent Res20007991652165811023259
   PubMed Web of Science ®Google Scholar
• LealSCBittarJPortugalAFalcãoDPFaberJZanottaPMedication in elderly people: its influence on salivary pattern, signs and symptoms of dry mouthGerodontology201027212913320337727
   PubMed Web of Science ®Google Scholar
• AstorFCHanftKLCioconJOXerostomia: a prevalent condition in the elderlyEar Nose Throat J199978747647910429321
   PubMedGoogle Scholar
• LiuBDionMRJurasicMMGibsonGJonesJAXerostomia and salivary hypofunction in vulnerable elders: prevalence and etiologyOral Surg Oral Med Oral Pathol Oral Radiol20121141526022727092
   PubMed Web of Science ®Google Scholar
• LockerDSubjective reports of oral dryness in an older adult populationCommunity Dent Oral Epidemiol19932131651688348792
   PubMed Web of Science ®Google Scholar
• ThorseliusIEmilsonCGOsterbergTSalivary conditions and drug consumption in older age groups of elderly Swedish individualsGerodontics19884266703209028
   PubMedGoogle Scholar
• NaglerRMSalivary glands and the aging process: mechanistic aspects, health-status and medicinal-efficacy monitoringBiogerontology20045422323315314272
   PubMed Web of Science ®Google Scholar
• ValdezIHFoxPCDiagnosis and management of salivary dysfunctionCrit Rev Oral Biol Med199343–42712778373984
   PubMedGoogle Scholar
• FoxPCBuschKABaumBJSubjective reports of xerostomia and objective measures of salivary gland performanceJ Am Dent Assoc198711545815843477595
   PubMed Web of Science ®Google Scholar
• ThomsonWMChalmersJMSpencerAJWilliamsSMThe Xerostomia Inventory: a multi-item approach to measuring dry mouthCommunity Dent Health1999161121710697349
   PubMed Web of Science ®Google Scholar
• SreebnyLMValdiniAXerostomia. Part I: Relationship to other oral symptoms and salivary gland hypofunctionOral Surg Oral Med Oral Pathol19886644514583186220
   PubMedGoogle Scholar
• EisbruchARhodusNRosenthalDHow should we measure and report radiotherapy-induced xerostomia?Semin Radiat Oncol200313322623412903012
   PubMed Web of Science ®Google Scholar
• PaiSGhezziEMShipJADevelopment of a Visual Analogue Scale questionnaire for subjective assessment of salivary dysfunctionOral Surg Oral Med Oral Pathol Oral Radiol Endod200191331131611250628
   PubMed Web of Science ®Google Scholar
• SinghMLPapasAOral Implications of Polypharmacy in the ElderlyDent Clin North Am201458478379625201542
   PubMedGoogle Scholar
• SmidtDTorpetLANauntofteBHeegaardKMPedersenAMAssociations between labial and whole salivary flow rates, systemic diseases and medications in a sample of older peopleCommunity Dent Oral Epidemiol201038542243520545715
   PubMed Web of Science ®Google Scholar
• OsailanSPramanikRShirodariaSChallacombeSJProctorGBInvestigating the relationship between hyposalivation and mucosal wetnessOral Dis201117110911421029258
   PubMed Web of Science ®Google Scholar
• LöfgrenCDWickströmCSonessonMLagunasPTChristerssonCA systematic review of methods to diagnose oral dryness and salivary gland functionBMC Oral Health2012122922870895
   PubMed Web of Science ®Google Scholar
• NavazeshMMethods for collecting salivaAnn N Y Acad Sci199369472778215087
   PubMed Web of Science ®Google Scholar
• ChenAWaiYLeeLLakeSWooSBUsing the modified Schirmer test to measure mouth dryness: a preliminary studyJ Am Dent Assoc20051362164170 quiz 229–23015782519
   PubMed Web of Science ®Google Scholar
• NavazeshMKumarSKUniversity of Southern California School of DentistryMeasuring salivary flow: challenges and opportunitiesJ Am Dent Assoc2008139Suppl35S40S18460678
   PubMedGoogle Scholar
• LashleyKSReflex secretion of the human parotid glandJ Exp Psychol191616461493
   Google Scholar
• SchneyerLHMethod for the collection of separate submaxillary and sublingual salivas in manJ Dent Res195534225726114367622
   PubMedGoogle Scholar
• WolffABegleiterAMoskonaDA novel system of human submandibular/sublingual saliva collectionJ Dent Res19977611178217869372796
   PubMed Web of Science ®Google Scholar
• EliassonLCarlénAAn update on minor salivary gland secretionsEur J Oral Sci2010118543544220831576
   PubMed Web of Science ®Google Scholar
• SmidtDTorpetLANauntofteBHeegaardKMPedersenAMAssociations between oral and ocular dryness, labial and whole salivary flow rates, systemic diseases and medications in a sample of older peopleCommunity Dent Oral Epidemiol201139327628821070322
   PubMed Web of Science ®Google Scholar
• VisvanathanVNixPManaging the patient presenting with xerostomia: a reviewInt J Clin Pract201064340440719817913
   PubMed Web of Science ®Google Scholar
• TakakuraACMoreiraTSLaitanoSCDe Luca JúniorLARenziAMenaniJVCentral muscarinic receptors signal pilocarpine-induced salivationJ Dent Res2003821299399714630901
   PubMed Web of Science ®Google Scholar
• WisemanLRFauldsDOral pilocarpine: a review of its pharmacological properties and clinical potential in xerostomiaDrugs19954911431557705213
   PubMed Web of Science ®Google Scholar
• IwabuchiYMasuharaTSialogogic activities of SNI-2011 compared with those of pilocarpine and McN-A-343 in rat salivary glands: identification of a potential therapeutic agent for treatment of Sjorgen’s syndromeGen Pharmacol19942511231297517901
   PubMedGoogle Scholar
• IwabuchiYKatagiriMMasuharaTSalivary secretion and histopathological effects after single administration of the muscarinic agonist SNI-2011 in MRL/lpr miceArch Int Pharmacodyn Ther199432833153257542865
   PubMedGoogle Scholar
• WeberJKeatingGMCevimelineDrugs200868121691169818681491
   PubMed Web of Science ®Google Scholar
• ChambersMSJonesCUBielMAOpen-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomiaInt J Radiat Oncol Biol Phys20076951369137617855005
   PubMed Web of Science ®Google Scholar
• BragaMATarziaOBergamaschiCCSantosFAAndradeEDGroppoFCComparison of the effects of pilocarpine and cevimeline on salivary flowInt J Dent Hyg20097212613019416095
   PubMed Web of Science ®Google Scholar
• AframianDJHelcerMLivniDRobinsonSDMarkitziuANadlerCPilocarpine treatment in a mixed cohort of xerostomic patientsOral Dis2007131889217241436
   PubMed Web of Science ®Google Scholar
• HamadaTNakaneTKimuraTTreatment of xerostomia with the bile secretion-stimulating drug anethole trithione: a clinical trialAm J Med Sci1999318314615110487404
   PubMed Web of Science ®Google Scholar
• BagheriHSchmittLBerlanMMontastrucJLA comparative study of the effects of yohimbine and anetholtrithione on salivary secretion in depressed patients treated with psychotropic drugsEur J Clin Pharmacol19975253393429272401
   PubMed Web of Science ®Google Scholar
• Gómez-MorenoGGuardiaJAguilar-SalvatierraACabrera-AyalaMMaté-Sánchez de-ValJECalvo-GuiradoJLEffectiveness of malic acid 1% in patients with xerostomia induced by antihypertensive drugsMed Oral Patol Oral Cir Bucal2013181e49e5522926481
   PubMed Web of Science ®Google Scholar
• Gómez-MorenoGAguilar-SalvatierraAGuardiaJThe efficacy of a topical sialogogue spray containing 1% malic acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trialDepress Anxiety201330213714223124914
   PubMed Web of Science ®Google Scholar
• FurnessSWorthingtonHVBryanGBirchenoughSMcMillanRInterventions for the management of dry mouth: topical therapiesCochrane Database Syst Rev201112CD00893422161442
   PubMed Web of Science ®Google Scholar
• OlssonHSpakCJAxéllTThe effect of a chewing gum on salivary secretion, oral mucosal friction, and the feeling of dry mouth in xerostomic patientsActa Odontol Scand19914952732791803848
   PubMed Web of Science ®Google Scholar
• MoulySJOrlerJBTilletYEfficacy of a new oral lubricant solution in the management of psychotropic drug-induced xerostomia: a randomized controlled trialJ Clin Psychopharmacol200727543744317873673
   PubMed Web of Science ®Google Scholar
• van der ReijdenWAVissinkAVeermanECAmerongenAVTreatment of oral dryness related complaints (xerostomia) in Sjögren’s syndromeAnn Rheum Dis199958846547410419864
   PubMed Web of Science ®Google Scholar
• AframianDJMizrahiBGranotIDombAJEvaluation of a mucoadhesive lipid-based bioerodable tablet compared with Biotène mouthwash for dry mouth relief – a pilot studyQuintessence Int2010413e36e4220213013
   PubMed Web of Science ®Google Scholar
• Blixt-JohansenGEkACGanowiakWImprovement of oral mucosa with mucin containing artificial saliva in geriatric patientsArch Gerontol Geriatr199214219320115374404
   PubMed Web of Science ®Google Scholar
• DuxburyAJThakkerNSWastellDGA double-blind cross-over trial of a mucin-containing artificial salivaBr Dent J198916641151202465774
   PubMed Web of Science ®Google Scholar
• van der ReijdenWAvan der KwaakHVissinkAVeermanECAmerongenAVTreatment of xerostomia with polymer-based saliva substitutes in patients with Sjögren’s syndromeArthritis Rheum199639157638546739
   PubMedGoogle Scholar
• SweeneyMPBaggJBaxterWPAitchisonTCClinical trial of a mucin-containing oral spray for treatment of xerostomia in hospice patientsPalliat Med19971132252329205656
   PubMed Web of Science ®Google Scholar
• GravenmadeEJVissinkAMucin-containing lozenges in the treatment of intraoral problems associated with Sjögren’s syndrome. A double-blind crossover study in 42 patientsOral Surg Oral Med Oral Pathol19937544664718464611
   PubMedGoogle Scholar
• ShipJAMcCutcheonJASpivakovskySKerrARSafety and effectiveness of topical dry mouth products containing olive oil, betaine, and xylitol in reducing xerostomia for polypharmacy-induced dry mouthJ Oral Rehabil2007341072473217824884
   PubMed Web of Science ®Google Scholar
• DonatskyOJohnsenTHolmstrupPBertramUEffect of Saliment on parotid salivary gland secretion and on xerostomia caused by Sjögren’s syndromeScand J Dent Res19829021571627041242
   PubMedGoogle Scholar
• JellemaAPLangendijkHBergenhenegouwenLThe efficacy of Xialine in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot-studyRadiother Oncol200159215716011325444
   PubMed Web of Science ®Google Scholar
• PerssonALingströmPBergdahlMClaessonRvan DijkenJWBuffering effect of a prophylactic gel on dental plaque in institutionalised elderlyGerodontology20072429810417518957
   PubMed Web of Science ®Google Scholar
• StewartCMJonesACBatesRESandowPPinkFStillwellJComparison between saliva stimulants and a saliva substitute in patients with xerostomia and hyposalivationSpec Care Dentist199818414214810218061
   PubMedGoogle Scholar
• RegelinkGVissinkAReintsemaHNautaJMEfficacy of a synthetic polymer saliva substitute in reducing oral complaints of patients suffering from irradiation-induced xerostomiaQuintessence Int19982963833889728149
   PubMed Web of Science ®Google Scholar
• FurumotoEKBarkerGJCarter-HansonCBarkerBFSubjective and clinical evaluation of oral lubricants in xerostomic patientsSpec Care Dentist19981831131189680921
   PubMedGoogle Scholar
• FoxPCCumminsMJCumminsJMUse of orally administered anhydrous crystalline maltose for relief of dry mouthJ Altern Complement Med200171334311246934
   PubMed Web of Science ®Google Scholar
• KhosravaniNBirkhedDEkströmJThe cholinesterase inhibitor physostigmine for the local treatment of dry mouth: a randomized studyEur J Oral Sci200911720921719583746
   PubMed Web of Science ®Google Scholar
• SreebnyLMValdiniAXerostomia. A neglected symptomArch Intern Med19871477133313373300589
   PubMedGoogle Scholar
• AzodoCCEzejaEBOmoaregbaJOJamesBOOral health of psychiatric patients: the nurse’s perspectiveInt J Dent Hyg201210424524922192470
   PubMed Web of Science ®Google Scholar
• TrindadeEMenonDTopferLAColomaCAdverse effects associated with selective serotonin reuptake inhibitors and tricyclic antidepressants: a meta-analysisCMAJ199815910124512529861221
   PubMed Web of Science ®Google Scholar
• StrietzelFPLafaurieGIMendozaGREfficacy and safety of an intraoral electrostimulation device for xerostomia relief: a multicenter, randomized trialArthritis Rheum201163118019020882668
   PubMedGoogle Scholar
• StrietzelFPMartin-GranizoRFedeleSElectrostimulating device in the management of xerostomiaOral Dis200713220621317305624
   PubMed Web of Science ®Google Scholar
• AlajbegIFalcãoDPTranSDIntraoral electrostimulator for xerostomia relief: a long-term, multicenter, open-label, uncontrolled, clinical trialOral Surg Oral Med Oral Pathol Oral Radiol2012113677378122668705
   PubMed Web of Science ®Google Scholar
• BlomMDawidsonIAngmar-MånssonBThe effect of acupuncture on salivary flow rates in patients with xerostomiaOral Surg Oral Med Oral Pathol19927332932981545961
   PubMedGoogle Scholar
• O’SullivanEMHigginsonIJClinical effectiveness and safety of acupuncture in the treatment of irradiation-induced xerostomia in patients with head and neck cancer: a systematic reviewAcupunct Med201028419119921062848
   PubMed Web of Science ®Google Scholar
• GuJZhuSLiXWuHLiYHuaFEffect of amifostine in head and neck cancer patients treated with radiotherapy: a systematic review and meta-analysis based on randomized controlled trialsPLoS One201495e9596824788761
   PubMed Web of Science ®Google Scholar