169
Views
42
CrossRef citations to date
0
Altmetric
Expert Opinion

The unsolved case of “bone-impairing analgesics”: the endocrine effects of opioids on bone metabolism

, , &
Pages 515-523 | Published online: 31 Mar 2015

References

  • BreivikHCollettBVentafriddaVCohenRGallacherDSurvey of chronic pain in Europe: prevalence, impact on daily life, and treatmentEur J Pain200610428733316095934
  • LangleyPCThe prevalence, correlates and treatment of pain in the European UnionCurr Med Res Opin201127246348021194390
  • WoolfCJAmerican College of Physicians; American Physiological SocietyPain: moving from symptom control toward mechanism-specific pharmacological managementAnn Intern Med2004140644145115023710
  • VentafriddaVTamburiniMCaraceniADe ConnoFNaldiFA validation study of the WHO method for cancer pain reliefCancer19875948508563802043
  • ColuzziFBertiMChange Pain: changing the approach to chronic painMinerva Med2011102428930721959703
  • PergolizziJAhlbeckKAldingtonDThe chronic pain conundrum: should we CHANGE from relying on past history to assessing prognostic factors?Curr Med Res Opin201228224925622181344
  • MattiaCDi BussoloEColuzziFNon-analgesic effects of opioids: the interaction of opioids with bone and jointsCurr Pharm Des201218376005600922747537
  • BuckeridgeDHuangAHanleyJRisk of injury associated with opioid use in older adultsJ Am Geriatr Soc20105891664167020863326
  • RubensteinLZJosephsonKRFalls and their prevention in elderly people: what does the evidence show?Med Clin North Am200690580782416962843
  • KressHGAhlbeckKAldingtonDManaging chronic pain in elderly patients requires a CHANGE of approachCurr Med Res Opin20143061153116424450746
  • DziechciażMBalicka-AdamikLFilipRThe problem of pain in old ageAnn Agric Environ Med2013;Spec no. 1353825000839
  • EnsrudKEBlackwellTMangioneCMStudy of Osteoporotic Fractures Research GroupCentral nervous system active medications and risk for fractures in older womenArch Intern Med2003163894995712719205
  • VestergaardPRejnmarkLMosekildeLFracture risk associated with the use of morphine and opiatesJ Intern Med20062601768716789982
  • LiLSetoguchiSCabralHJickSOpioid use for noncancer pain and risk of fracture in adults: a nested case-control study using the general practice research databaseAm J Epidemiol2013178455956923639937
  • LandiFOnderGCesariMBarillaroCRussoABernabeiRSilver Network Home Care Study GroupPsychotropic medications and risk for falls among community-dwelling frail older people: an observational studyJ Gerontol A Biol Sci Med Sci200560562262615972615
  • VestergaardPHermannPJensenJEEikenPMosekildeLEffects of paracetemol, non-steroidal anti-inflammatory drugs, acetylsalicylic acid, and opioids on bone mineral density and risk of fracture: results of the Danish Osteoporosis Prevention Study (DOPS)Osteoporos Int20122341255126521710339
  • RussellRGEspinaBHulleyPBone biology and the pathogenesis of osteoporosisCurr Opin Rheumatol200618Suppl 1S3S1016735843
  • RaiszLGPathogenesis of osteoporosis: concepts, conflicts, and prospectsJ Clin Invest2005115123318332516322775
  • DelaisseJMThe reversal phase of the bone-remodeling cycle: cellular prerequisites for coupling resorption and formationBonekey Rep2014356125120911
  • WalshMCChoiYBiology of the RANKL-RANK-OPG system in immunity, bone, and beyondFront Immunol2014551125368616
  • ColuzziFDi BussoloEMandatoriIMattiaCBone metastatic disease: taking aim at new therapeutic targetsCurr Med Chem201118203093311521651483
  • ColuzziFMandatoriIMattiaCEmerging therapies in metastatic bone painExpert Opin Emerg Drugs201116344145821545247
  • PandayKGonaAHumphreyMBMedication-induced osteoporosis: screening and treatment strategiesTher Adv Musculoskelet Dis20146518520225342997
  • DaniellHWOpioid osteoporosisArch Intern Med20041643338 author reply 338.14769633
  • KinjoMSetoguchiSSchneeweissSSolomonDHBone mineral density in subjects using central nervous system-active medicationsAm J Med200511812141416378792
  • NelsonRENebekerJRSauerBCLaFleurJFactors associated with screening or treatment initiation among male United States veterans at risk for osteoporosis fractureBone201250498398822266156
  • Pérez-CastrillónJLOlmosJMGómezJJExpression of opioid receptors in osteoblast-like MG-63 cells, and effects of different opioid agonists on alkaline phosphatase and osteocalcin secretion by these cellsNeuroendocrinology200072318719411025413
  • RosenHBar-ShavitZDual role of osteoblastic proenkephalin derived peptides in skeletal tissuesJ Cell Biochem19945533343397962165
  • RicoHCostalesCCabranesJAEscuderoMLower serum osteocalcin levels in pregnant drug users and their newborns at the time of deliveryObstet Gynecol199075699810002342747
  • BoshraVEvaluation of osteoporosis risk associated with chronic use of morphine, fentanyl and tramadol in adult female ratsCurr Drug Saf20116315916322122391
  • ElliottJAHortonEFibuchEEThe endocrine effects of long-term oral opioid therapy: a case report and review of the literatureJ Opioid Manag20117214515421561038
  • DuarteRVRaphaelJHSouthallJLLabibMHWhallettAJAshfordRLHypogonadism and low bone mineral density in patients on long-term intrathecal opioid delivery therapyBMJ Open201336
  • KatzNMazerNAThe impact of opioids on the endocrine systemClin J Pain200925217017519333165
  • VuongCVan UumSHO’DellLELutfyKFriedmanTCThe effects of opioids and opioid analogs on animal and human endocrine systemsEndocr Rev20103119813219903933
  • DaniellHWOpioid endocrinopathy in women consuming prescribed sustained-action opioids for control of nonmalignant painJ Pain200891283617936076
  • VanderschuerenDLaurentMRClaessensFSex steroid actions in male boneEndocr Rev201435690696025202834
  • SmithHSElliottJAOpioid-induced androgen deficiency (OPIAD)Pain Physician2012153 SupplSE145SE156
  • DaniellHWLentzRMazerNAOpen-label pilot study of testosterone patch therapy in men with opioid-induced androgen deficiencyJ Pain20067320021016516826
  • DaniellHWHypogonadism in men consuming sustained-action oral opioidsJ Pain20023537738414622741
  • DaniellHWDHEAS deficiency during consumption of sustained-action prescribed opioids: evidence for opioid-induced inhibition of adrenal androgen productionJ Pain200671290190717157776
  • VodoSArcelliDFiorenzaniPGonadal ERα/β, AR and TRPV1 gene expression: modulation by pain and morphine treatment in male and female ratsPhysiol Behav2013110–1118086
  • ColamecoSCorenJSOpioid-induced endocrinopathyJ Am Osteopath Assoc20091091202519193821
  • PolicolaCStokesVKaravitakiNGrossmanAAdrenal insufficiency in acute oral opiate therapyEndocrinol Diabetes Metab Case Rep2014201413007124683482
  • KesmatiMRezaieMFathi-MoghaddamHInteraction between glucocorticoids and opioids in nociception in young and adult ratsOpen Access Anim Physiol2010201028792
  • IrwigMSBone health in hypogonadal menCurr Opin Urol201424660861325144148
  • PedrazzoniMVescoviPPManinettiLEffects of chronic heroin abuse on bone and mineral metabolismActa Endocrinol (Copenh)1993129142458351958
  • KimTWAlfordDPMalabananAHolickMFSametJHLow bone density in patients receiving methadone maintenance treatmentDrug Alcohol Depend200685325826216860495
  • GreyARix-TrottKHorneAGambleGBollandMReidIRDecreased bone density in men on methadone maintenance therapyAddiction2011106234935420955216
  • ArnstenJHFreemanRHowardAAFloris-MooreMSantoroNSchoenbaumEEHIV infection and bone mineral density in middle-aged womenClin Infect Dis20064271014102016511769
  • ArnstenJHFreemanRHowardAAFloris-MooreMLoYKleinRSDecreased bone mineral density and increased fracture risk in aging men with or at risk for HIV infectionAIDS200721561762317314524
  • NapoliNFaccioRShresthaVBucchieriSRiniGBArmamento-VillarealREstrogen metabolism modulates bone density in menCalcif Tissue Int200780422723217406768
  • VanderschuerenDVandenputLBoonenSLindbergMKBouillonROhlssonCAndrogens and boneEndocr Rev200425338942515180950
  • GiriMKaufmanJMOpioidergic modulation of in vitro pulsatile gonadotropin-releasing hormone release from the isolated medial basal hypothalamus of the male guinea pigEndocrinology19941355213721437956937
  • FraserLAMorrisonDMorley-ForsterPOral opioids for chronic non-cancer pain: higher prevalence of hypogonadism in men than in womenExp Clin Endocrinol Diabetes20091171384318523930
  • FortinJDBaileyGMVilenskyJADoes opioid use for pain management warrant routine bone mass density screening in men?Pain Physician200811453954118690281
  • De MaddalenaCBelliniMBerraMMeriggiolaMCAloisiAMOpioid-induced hypogonadism: why and how to treat itPain Physician2012153 SupplSE111SE118
  • BrennanMJThe effect of opioid therapy on endocrine functionAm J Med20131263 Suppl 1S12S1823414717
  • CeccarelliIDe PadovaAMFiorenzaniPMassafraCAloisiAMSingle opioid administration modifies gonadal steroids in both the CNS and plasma of male ratsNeuroscience2006140392993716580783
  • AloisiAMAurilioCBachioccoVEndocrine consequences of opioid therapyPsychoneuroendocrinology200934Suppl 1S162S16819540049
  • AurilioCCeccarelliIPotaVEndocrine and behavioural effects of transdermal buprenorphine in pain-suffering women of different reproductive agesEndocr J201158121071107821937837
  • PergolizziJGoehlerKSteigerwaldIEtopolskiMKimMVorsangerGEffects of Tapentadol on level of sexual hormones associated with opioid-induced androgen deficiencyPoster presented at: PainWeek 2012Sept 5–82012Las Vegas, NV
  • MattiaCEditorial: non-analgesic effects of opioids: the dark side of the moonCurr Pharm Des201218375991599322747549