Ranolazine versus placebo in patients with ischemic cardiomyopathy and persistent chest pain or dyspnea despite optimal medical and revascularization therapy: randomized, double-blind crossover pilot study

Nicolas W Shammas1 Midwest Cardiovascular Research Foundation, Davenport, IA, USACorrespondence[email protected]

Gail A Shammas1 Midwest Cardiovascular Research Foundation, Davenport, IA, USA

Kathleen Keyes2 Cardiovascular Medicine, Private Corporation, Davenport, IA, USA

Shawna Duske1 Midwest Cardiovascular Research Foundation, Davenport, IA, USA

Ryan Kelly1 Midwest Cardiovascular Research Foundation, Davenport, IA, USA

Michael Jerin3 St Ambrose University, Davenport, IA, USA

Pages 469-474 | Published online: 23 Mar 2015

Cite this article
CrossMark

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

References

MentzRJFiuzatMShawLKComparison of clinical characteristics and long-term outcomes of patients with ischemic cardiomyopathy with versus without angina pectoris (from the Duke Databank for Cardiovascular Disease)Am J Cardiol201210991272127722325975
PubMed Web of Science ®Google Scholar
LevineTBLevineABVincenziAKeteyianSJBillingsJLeschMResponse of symptomatic myocardial ischemia in ischemic cardiomyopathy to intensive vasodilator therapyAm J Cardiol19978022122149230164
PubMed Web of Science ®Google Scholar
PasternacANobleJStreulensYElieRHenschkeCBourassaMGPathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteriesCirculation19826547787897199403
PubMedGoogle Scholar
ChaitmanBRSkettinoSLParkerJOMARISA InvestigatorsAnti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe anginaJ Am Coll Cardiol20044381375138215093870
PubMed Web of Science ®Google Scholar
ChaitmanBRPepineCJParkerJOCombination Assessment of Ranolazine In Stable Angina (CARISA) InvestigatorsEffects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trialJAMA2004291330931614734593
PubMed Web of Science ®Google Scholar
MorrowDASciricaBMKarwatowska-ProkopczukESkeneAMcCabeCHBraunwaldEMERLIN-TIMI 36 InvestigatorsEvaluation of a novel anti-ischemic agent in acute coronary syndromes: design and rationale for the Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-elevation acute coronary syndromes (MERLIN)-TIMI 36 trialAm Heart J200615161186.e11186.e916781216
PubMed Web of Science ®Google Scholar
SpertusJAJonesPMcDonellMFanVFihnSDHealth status predicts long-term outcome in outpatients with coronary diseaseCirculation20021061434912093768
PubMed Web of Science ®Google Scholar
RoseGABlackburnHCardiovascular survey methodsMonogr Ser World Health Organ1968561188
PubMedGoogle Scholar
BelardinelliLAntzelevitchCFraserHInhibition of late (sustained/persistent) sodium current: a potential drug target to reduce intracellular sodium-dependent calcium overload and its detrimental effects on car-diomyocyte functionEur Heart J Suppl20046Suppl IS13S17
Web of Science ®Google Scholar
PieskeBMaierLSPiacentinoVWeisserJHasenfussGHouserSRate dependence of [Na+]i and contractility in nonfailing and failing human myocardiumCirculation2002106444745312135944
PubMed Web of Science ®Google Scholar
WagnerSDybkovaNRasenackECCa2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channelsJ Clin Invest2006116123127313817124532
PubMed Web of Science ®Google Scholar
FihnSDGardinJMAbramsJAmerican College of Cardiology Foundation/American Heart Association Task Force2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic SurgeonsCirculation201212625e354e47123166211
PubMed Web of Science ®Google Scholar

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Ranolazine versus placebo in patients with ischemic cardiomyopathy and persistent chest pain or dyspnea despite optimal medical and revascularization therapy: randomized, double-blind crossover pilot study

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Ranolazine versus placebo in patients with ischemic cardiomyopathy and persistent chest pain or dyspnea despite optimal medical and revascularization therapy: randomized, double-blind crossover pilot study

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date