Managing opioid-induced constipation in advanced illness: focus on methylnaltrexone bromide

References

• ManciniIBrueraEConstipation in advanced cancer patientsSupport Care Cancer199863563649695203
   PubMed Web of Science ®Google Scholar
• VainioAAuvinenAPrevalence of symptoms among patients with advanced cancer: an international collaborative studyJ Pain Symptom Manage1996123108718910
   PubMed Web of Science ®Google Scholar
• FallonMTConstipation in cancer patients: prevalence, pathogenesis, and cost-related issuesEur J Pain19993suppl37
   Google Scholar
• GoodmanMLWilkinsonSLaxatives for the management of constipation in palliative care patientsThe Cochrane Library2004111
   Google Scholar
• BrueraESuarez-AlmazorMVelascoAThe assessment of constipation in terminal cancer patients admitted to a palliative care unit: a retrospective reviewJ Pain Symptom Manage199495155197531736
   PubMed Web of Science ®Google Scholar
• GoodmanMLowJWilkinsonSConstipation management in palliative care: a survey of practices in the United KingdomJ Pain Symptom Manage20052923824415781174
   PubMed Web of Science ®Google Scholar
• LarkinPJSykesNPCentenoCEuropean Consensus Group on Constipation in Palliative CareThe management of constipation in palliative care: clinical practice recommendationsPalliat Med20082279680718838491
   PubMed Web of Science ®Google Scholar
• ManciniIBrueraEConstipationRipamontiCBrueraEGastrointestinal Symptoms in Advanced Cancer PatientsNew YorkOxford University Press2002193206
   Google Scholar
• ChangLFrom Rome to Los Angeles – The Rome III Criteria for the Functional GI DisordersGastroenterology20061301480149116678561
   PubMed Web of Science ®Google Scholar
• KurzASesslerDIOpioid-induced bowel dysfunction: pathophysiology and potential new therapiesDrugs20036364967112656645
   PubMed Web of Science ®Google Scholar
• MikusGCombining opioid agonists and antagonists as a solution for opioid-induced constipationEuropean Gastroenterology and Hepatology Review20097174
   Google Scholar
• RamsinBTrescotAMDattaSOpioid complications and side effectsPain Physician200811S105S12018443635
   PubMed Web of Science ®Google Scholar
• ThomasJOpioid-induced bowel dysfunctionJ Pain Symptom Manage20083510311317981003
   PubMed Web of Science ®Google Scholar
• FallonMTHanksGWMorphine, constipation and performance status in advanced cancer patientsPalliat Med19991315916010474699
   PubMed Web of Science ®Google Scholar
• StewartWFLibermannJNSandlerRSEpidemiology of constipation (EPOC) Study in the United States: relation of clinical subtypes to socioeconomic featuresAm J Gastroenterol1999943530353910606315
   PubMed Web of Science ®Google Scholar
• WanitschkeRGoergKJLoewDDifferential therapy of constipation – a reviewInt J Clin Pharmacol Ther200341142112564741
   PubMed Web of Science ®Google Scholar
• ClemensKEKlaschikEManagement of constipation in palliative care patientsCurr Opin Support Palliat Care20082222718685390
   PubMedGoogle Scholar
• ClemensKEKlaschikEManaging nausea, emesis and constipation in palliative careDtsch Arztebl2007104269278
   Google Scholar
• ManaraLBianchiGFerrettiPTavaniAInhibitation of gastrointestinal transit by morphine in rats results primarily from direct drug action on gut opioid investigational sitesJ Pharmacol Exp Ther19862379459493012075
   PubMed Web of Science ®Google Scholar
• TavaniABianchiGFerrettiPManaraLMorphine most effective on gastrointestinal propulsion in rats by intraperitoneal route: evidence for local actionLife Sci198027221122177207014
   PubMed Web of Science ®Google Scholar
• KaufmanPNKreveskyBMalmudLSRole of opiate receptors in the regulation of colonic transitGastroenterology199894135113562834257
   PubMedGoogle Scholar
• JurnaIBaldaufJRetardiert freigesetztes Naloxon oral: Aufhebung der Obstipation durch orales Morphin ohne Beseitigung der AnalgesieDer Schmerz199373142118415396
   PubMedGoogle Scholar
• MeissnerWSchmidtUHartmannMOral naloxone reverses opioid-associated constipationPain20008410510910601678
   PubMed Web of Science ®Google Scholar
• ShaiovaLRimFFriedmanDJahdiMA review of methylnaltrexone, a peripheral opioid receptor antagonist, and its role in opioid-induced constipationPalliate Support Care20075161166
   PubMedGoogle Scholar
• HerndonCMJacksonKCHalllinPAManagement of opiod-induced gastrointestinal effects in patients receiving palliative carePharmacotherapy20022224025011837561
   PubMed Web of Science ®Google Scholar
• BeckerGBlumHENovel opioid-antagonists for opioid-induced bowel dysfunction and postoperative ileusLancet20093731198120619217656
   PubMed Web of Science ®Google Scholar
• BrownDRGoldbergLIThe use of quaternary narcotic antagonist in opiate researchNeuropharmacology1985241811922986035
   PubMed Web of Science ®Google Scholar
• YuanCSFossJFMethylnaltrexone: investigation of clinical applicationsDrug Dev Res200050133141
   Web of Science ®Google Scholar
• DeHaven-HudkinsDLDeHavenRNLittlePJTechnerLMThe involvement of the opioid receptor in gastrointestinal pathophysiology: therapeutic opportunities for antagonism at this receptorPharmaco Ther2008117162187
   PubMed Web of Science ®Google Scholar
• YuanCSIsraelRJMethylnaltrexone, a novel peripheral opioid receptor antagonist for the treatment of opioid side effectsExpert Opin Investig Drugs200615541552
   PubMed Web of Science ®Google Scholar
• ReichleFMConzenPFMethylnaltrexone, a new peripheral μ-receptor antagonist for the prevention and treatment of opioid-induced extracerebral side effectsCurr Opin Investig Drugs2008990100
   PubMedGoogle Scholar
• YuanSCDoshanHCharneyMRTolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humansJ Clin Pharmacol20054553854615831777
   PubMed Web of Science ®Google Scholar
• HolzerPNew approaches to the treatment of opioid-induced constipationEur Rev Medi Pharmacol Sci200812119127
   PubMed Web of Science ®Google Scholar
• RosowCEGomeryPChenTYStefanovichPStamblerNIsraelRReversal of opioid-induced bladder dysfunction by intravenous naloxone and methylnaltrexoneClin Pharmacol Ther200782485317392726
   PubMed Web of Science ®Google Scholar
• MurphyDBSuttonJAPrescottLFMurphyMBOpioid-induced delay in gastric emptying: a peripheral mechanism in humansAnesthesiology1997877657709357876
   PubMed Web of Science ®Google Scholar
• YuanCSFossJFO’ConnorMToledanoARoizenMFMossJMethylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: a double-blind randomized placebo-controlled trialClin Pharmacol Ther1996594694758612393
   PubMed Web of Science ®Google Scholar
• YuanCSFossJFOsinksiJToledanoARoizenMFMossJThe safety and efficacy of oral methylnaltrexone in preventing morphine-induced delay in oral-cecal transit-timeClin Pharmacol Ther1997614674759129564
   PubMed Web of Science ®Google Scholar
• YuanCSWeiGFossJFO’ConnorMKarrisonTOsinskiJEffects of subcutaneous methylnaltrexone on morphine-induced peripherally mediated side-effects: a double-blind randomized placebo-controlled trialJ Pharmacol Exp Ther200230011812311752106
   PubMed Web of Science ®Google Scholar
• ThomasJKarverSCooneyGAMethylnaltrexone for opioid-induced constipation in advanced illnessN Engl J Med20083582332234318509120
   PubMed Web of Science ®Google Scholar
• YuanCSFossJFO’ConnorMMethylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trialJAMA200028336737210647800
   PubMed Web of Science ®Google Scholar
• YuanCSFossFJOral methylnaltrexone for opioid-induced constipationJAMA2000111383138410989399
   PubMedGoogle Scholar
• BerdeCNurkoSOpioid side effects – mechanism-based therapyN Engl J Med20083582400240218509126
   PubMed Web of Science ®Google Scholar
• BeattieDTCheruvuMMaiNThe in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexoneNaunyn-Schmiedeberg’s Arch Pharmacol2007375205220
   Google Scholar
• McNicolEDBoyceDSchumannRCarrDBMu-opioid antagonists for opioid-induced bowel dysfunctionCochrane Database Syst Rev20082CD00633218425947
   PubMed Web of Science ®Google Scholar
• HerbertMKHolzerPStandardized concept for the treatment of gastrointestinal dysmotility in critically ill patients – current status and future optionsClin Nutr200827254117933437
   PubMed Web of Science ®Google Scholar
• YuanCSFossJFO’ConnorMOsinksiJRoizenMFMossJEffects of intravenous methylnaltrexone on opioid-induced gut motility and transit time changes in subjects receiving chronic methadone therapy: a pilot studyJ Pain199983631635
   Google Scholar
• NearyPDelaneyCPAlvimopanExpert Opin Investig Drugs200514479488
   PubMed Web of Science ®Google Scholar
• KotakeANKuwaharaSKBurtonEMcCoyCEGoldbergLIVariations in demethylation of N-methylnaterxone in mice, rats, dog, and humansXenobiotica198919124712542618077
   PubMed Web of Science ®Google Scholar
• European Medicines Agency (EMEA) URL: http://www.emea.europa.eu/, accessed 19 September 2009.
   Google Scholar