References
- Collaborative overview of randomised trials of antiplatelet therapy. In: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients Antiplatelet Trialists’ CollaborationBMJ19943086921811068298418
- WeismanSMGrahamDYEvaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular eventsArch Intern Med2002162192197220212390062
- YeomansNLanasALabenzJEfficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirinAm J Gastroenterol2008103102465247318637091
- LaineLReview article: gastrointestinal bleeding with low-dose aspirin – what’s the riskAliment Pharmacol Ther200691524689790816948802
- DerrySLokeYKRisk of gastrointestinal haemorrhage with long term use of aspirin: meta-analysisBMJ200032172701183118711073508
- WolfeMMLichtensteinDRSinghGGastrointestinal toxicity of nonsteroidal antiinflammatory drugsN Engl J Med1999340241888189910369853
- LanasAPerez-AisaMAFeuFA nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal antiinflammatory drug useAm J Gastroenterol200510081685169316086703
- NakayamaMIwakiriRHaraMLow-dose aspirin is a prominent cause of bleeding ulcers in patients who underwent emergency endoscopyJ Gastroenterol200944991291819436943
- VaneJRInhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugsNat New Biol1971231252322355284360
- RobertACytoprotection by prostaglandinsGastroenterology1979774 Pt 176176738173
- FeldmanMShewmakeKCryerBTime course inhibition of gastric and platelet COX activity by acetylsalicylic acid in humansAm J Physiol Gastrointest Liver Physiol20002795G11131112011053009
- McQuaidKRLaineLSystematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trialsAm J Med20068119862463816887404
- SorensenHTMellemkjaerLBlotWJRisk of upper gastrointestinal bleeding associated with use of low-dose aspirinAm J Gastroenterol20009592218222411007221
- LanasABajadorESerranoPNitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleedingN Engl J Med20003431283483910995862
- SerranoPLanasAArroyoMTFerreiraIJRisk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseasesAliment Pharmacol Ther200216111945195312390104
- WeilJColin-JonesDLangmanMProphylactic aspirin and risk of peptic ulcer bleedingBMJ199531069838278307711618
- HuangJQSridharSHuntRHRole of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in pepticulcer disease: a meta-analysisLancet20023599300142211809181
- ChanFKChungSCSuenBYPreventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxenN Engl J Med20013441396797311274623
- LaiKCLamSKChuKMLansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin useN Engl J Med2002346262033203812087138
- ChanFKLong-term incidence of ulcer bleeding with low-dose aspiring after eradication of H. pylori: A 4-year prospective cohort study [abstract]Gastroenterology2005128A133
- PilottoAFranceschiMLongoaMGHelicobacter pylori infection and the prevention of peptic ulcer with proton pump inhibitors in elderly subjects taking low-dose aspirinDig Liver Dis2004361066667015506665
- YusufSZhaoFMehtaSRChrolaviciusSTognoniGFoxKKEffects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevationN Engl J Med2001345749450211519503
- DienerHCBogousslavskyJBrassLMAspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trialLancet2004364943133133715276392
- BhattDLFoxKAHackeWClopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic eventsN Engl J Med2006354161706171716531616
- HanssonLZanchettiACarruthersSGEffects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study GroupLancet19983519118175517629635947
- PatronoCGarcia RodriguezLALandolfiRBaigentCLow-dose aspirin for the prevention of atherothrombosisN Engl J Med2005353222373238316319386
- AndreottiFTestaLBiondi-ZoccaiGGCreaFAspirin plus warfarin compared to aspirin alone after acute coronary syndromes: an updated and comprehensive meta-analysis of 25,307 patientsEur Heart J200627551952616143706
- NielsenGLSorensenHTMellemkjoerLRisk of hospitalization resulting from upper gastrointestinal bleeding among patients taking corticosteroids: a register-based cohort studyAm J Med2001111754154511705430
- de AbajoFJGarcia RodriguezLARisk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulationsBMC Clin Pharmacol20011111228592
- TaylorDWBarnettHJHaynesRBLow-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial. ASA and Carotid Endarterectomy (ACE) Trial CollaboratorsLancet199935391712179218410392981
- BaronJAColeBFSandlerRSA randomized trial of aspirin to prevent colorectal adenomasN Engl J Med20033481089189912621133
- KellyJPKaufmanDWJurgelonJMSheehanJKoffRSShapiroSRisk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered productLancet19963489039141314168937281
- PenneyAGAndrewsFJO’BrienPEEffects of misoprostol on delayed ulcer healing induced by aspirinDig Dis Sci19943959349398174434
- RothSAgrawalNMahowaldMMisoprostol heals gastroduodenal injury in patients with rheumatoid arthritis receiving aspirinArch Intern Med198914947757792495779
- WatanabeTSugimoriSKamedaNSmall bowel injury by low-dose enteric-coated aspirin and treatment with misoprostol: a pilot studyClin Gastroenterol Hepatol20086111279128218995219
- DonnellyMTGoddardAFFilipowiczBMorantSVShieldMJHawkeyCJLow-dose misoprostol for the prevention of low-dose aspirin-induced gastroduodenal injuryAliment Pharmacol Ther200014552953410792114
- RostomADubeCWellsGPrevention of NSAID-induced gastro-duodenal ulcersCochrane Database Syst Rev20024CD00229612519573
- LeontiadisGISreedharanADorwardSSystematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleedingHealth Technol Assess20071151iiiiv1164
- HawkeyCJKarraschJASzczepanskiLOmeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study GroupN Engl J Med1998338117277349494149
- YeomansNDTulassayZJuhaszLA comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-associated Ulcer Treatment (ASTRONAUT) Study GroupN Engl J Med1998338117197269494148
- LanasARodrigoLMarquezJLLow frequency of upper gastrointestinal complications in a cohort of high-risk patients taking low-dose aspirin or NSAIDS and omeprazoleScand J Gastroenterol200338769370012889553
- GoldsteinJLJohansonJFSuchowerLJBrownKAHealing of gastric ulcers with esomeprazole versus ranitidine in patients who continued to receive NSAID therapy: a randomized trialAm J Gastroenterol2005100122650265716393215
- ScheimanJMYeomansNDTalleyNJPrevention of ulcers by esomeprazole in at-risk patients using non-selective NSAIDs and COX-2 inhibitorsAm J Gastroenterol2006101470171016494585
- ChanFKChingJYHungLCClopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleedingN Engl J Med2005352323824415659723
- LaiKCChuKMHuiWMEsomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complicationsClin Gastroenterol Hepatol20064786086516797240
- VachhaniROldsGVelanovichVEsomeprazole: a proton pump inhibitorExpert Rev Gastroenterol Hepatol200931152719210109
- NiaziMAnderssonTNauclerESundinMNaesdalJEvaluation of the pharmacokinetic interaction between esomeprazole (40 mg) and acetylsalicylic acid (325 mg) in healthy volunteersInt J Clin Pharmacol Ther200947956456919761715
- BhattDLScheimanJAbrahamNSACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID useAm J Gastroenterol2008103112890290718853965
- LaineLHennekensCProton pump inhibitor and clopidogrel interaction: fact or fiction?Am J Gastroenterol20101051344119904241