Critical limb ischemia: current challenges and future prospects

References

• MurabitoJMEvansJCNietoKLarsonMGLevyDWilsonPWPrevalence and clinical correlates of peripheral arterial disease in the Framingham Offspring StudyAm Heart J2002143696196512075249
   PubMed Web of Science ®Google Scholar
• AdamDJBeardJDClevelandTBASIL trial participantsBypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trialLancet200536695011925193416325694
   PubMed Web of Science ®Google Scholar
• StoyioglouAJaffMRMedical treatment of peripheral arterial disease: a comprehensive reviewJ Vasc Interv Radiol200415111197120715525738
   PubMed Web of Science ®Google Scholar
• StegPGBhattDLWilsonPWREACH Registry InvestigatorsOne-year cardiovascular event rates in outpatients with atherothrombosisJAMA2007297111197120617374814
   PubMed Web of Science ®Google Scholar
• CaroJMigliaccio-WalleKIshakKJProskorovskyIThe morbidity and mortality following a diagnosis of peripheral arterial disease: long-term follow-up of a large databaseBMC Cardiovasc Disord200551415972099
   PubMedGoogle Scholar
• Abu DabrhAMSteffenMWUndavalliCThe natural history of untreated severe or critical limb ischemiaJ Vasc Surg20156261642165126391460
   PubMed Web of Science ®Google Scholar
• NorgrenLHiattWRDormandyJANehlerMRHarrisKAFowkesFGIntersociety consensus for the management of peripheral arterial disease (TASC II)J Vasc Surg200745suppl SS5S6717223489
   PubMed Web of Science ®Google Scholar
• StrandnessDJSumnerDHemodynamics for SurgeonsNew YorkGrune & Stratton1975278281
   Google Scholar
• CriquiMHFronekAKlauberMRBarret-ConnorEGabrielSThe sensitivity, specificity, and predictive value of traditional clinical evaluation of peripheral arterial disease: results from noninvasive testing in a defined populationCirculation19857135165223156007
   PubMed Web of Science ®Google Scholar
• OrchardJStrandnessDEJrAssessment of peripheral vascular disease in diabetes. Report and recommendations of an international workshop sponsored by the American Heart association and the American Diabetes AssociationDiabetes Care19931611191209
   Web of Science ®Google Scholar
• YoungMJAdamsJEAndersonGFBoultonAJCavanaghPRMedial arterial calcification in the feet of diabetic patients and matched non-diabetic control subjectsDiabetologia19933676156218359578
   PubMed Web of Science ®Google Scholar
• ParkSCChoiCYHaYIYangHEUtility of toe-brachial index for diagnosis of peripheral artery diseaseArch Plast Surg201239322723122783531
   PubMedGoogle Scholar
• BalladJLEkeCCBuntTJKillenJDA prospective evaluation of transcutaneous oxygen measurements in the management of diabetic foot problemsJ Vasc Surg19952244854907563410
   PubMed Web of Science ®Google Scholar
• BradburyAWAdamDJDiagnosis of peripheral arterial disease of the lower limbBMJ200733476061229123017569893
   PubMedGoogle Scholar
• VisserKHuninkMGPeripheral arterial disease: gadolinium-enhanced MR angiography versus color color-guided duplex: a meta-analysisRadiology20002161677710887229
   PubMed Web of Science ®Google Scholar
• HingoraniAAscherEMarksNPreprocedural imaging: new options to reduce need for contrast angiographySemin Vasc Surg2007201152817386360
   PubMed Web of Science ®Google Scholar
• PrinceMRZhangHMorrisMIncidence of nephrogenic systemic fibrosis at two large medical centersRadiology2008248380781618710976
   PubMed Web of Science ®Google Scholar
• RydahlCThomsenHSMarckmannPHigh prevalence of nephrogenic systemic fibrosis in chronic renal failure patients exposed to gadodiamide, a gadolinium-containing magnetic resonance contrast agentInvest Radiol200843214114418197066
   PubMed Web of Science ®Google Scholar
• WertmanRAltunEMartinDRRisk of nephrogenic systemic fibrosis: evaluation of gadolinium chelate contrast agents at four American UniversitiesRadiology2008248379980618632533
   PubMed Web of Science ®Google Scholar
• MetRBipatSLegemateDAReekersJAKoelemayMJDiagnostic performance of computed tomography angiography in peripheral arterial disease: a systematic review and meta-analysisJAMA2009301441542419176443
   PubMed Web of Science ®Google Scholar
• StegemannETegtmeierCBimpong-ButaNYCarbondioxide- aided angiography decreases contrast volume and preserves kidney function in peripheral vascular interventionsAngiology201667987588126535013
   PubMed Web of Science ®Google Scholar
• WilligendaelEMTeijinkJABartelinkMLPetersRJBullerHRPrinsMHSmoking and the patency of lower extremity bypass grafts: a meta-analysisJ Vasc Surg2005421677416012454
   PubMed Web of Science ®Google Scholar
• ArmstrongEJWuJSinghGDSmoking cessation is associated with decreased mortality and improved amputation-free survival among patients with symptomatic peripheral artery diseaseJ Vasc Surg20146061565157125282696
   PubMed Web of Science ®Google Scholar
• Heart Protection Study Collaborative GroupMRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trialLancet2002360932672212114036
   PubMed Web of Science ®Google Scholar
• HirschATHaskalZJHertzerNRACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): executive summary a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA task force on practice guidelines (writing committee to develop guidelines for the management of patients with peripheral arterial disease) endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; Trans-Atlantic Inter-Society Consensus; and Vascular Disease FoundationJ Am Coll Cardiol2006471239131216545667
   PubMed Web of Science ®Google Scholar
• RubinsHBRobinsSJCollinsDGemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans affairs high-density lipoprotein cholesterol intervention trial study groupN Engl J Med1999341641041810438259
   PubMed Web of Science ®Google Scholar
• ESH/ESC2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertensionJ Hypertens20032161011105312777938
   PubMed Web of Science ®Google Scholar
• XXXXIntensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) groupLancet199835291318378539742976
   PubMed Web of Science ®Google Scholar
• DormandyJACharbonnelBEcklandDJPROactive Investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular events): a randomised controlled trialLancet200536694931279128916214598
   PubMed Web of Science ®Google Scholar
• GiuratoLVainieriEMeloniMLimb salvage in patients with diabetes is not a temporary solution but a life-changing procedureDiabetes Care20153810e156e15726294664
   PubMed Web of Science ®Google Scholar
• UccioliLGandiniRGiuratoLLong-term outcomes of diabetic patients with critical limb ischemia followed in a tertiary referral diabetic foot clinicDiabetes Care201033597798220200304
   PubMed Web of Science ®Google Scholar
• OwenRJHiremathSMyersAFraser-HillMBarrettBJCanadian association of radiologists consensus guidelines for the prevention of contrast-induced nephropathy: update 2012Can Assoc Radiol J20146529610524559602
   PubMed Web of Science ®Google Scholar
• Antithrombotic Trialists’ CollaborationCollaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patientsBr Med J20023247329718611786451
   PubMed Web of Science ®Google Scholar
• AielloAAnichiniRBroccoETreatment of peripheral arterial disease in diabetes: a consensus of the Italian Societies of Diabetes (SID, AMD), Radiology (SIRM) and Vascular Endovascular Surgery (SICVE)Nutr Metab Cardiovasc Dis201424435536924486336
   PubMed Web of Science ®Google Scholar
• BradburyAWRuckleyCVFowkesFGRBypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trialLancet2002366200519251934
   Google Scholar
• RomitiMAlbersMBrochado-NetoFCDurazzoAEPereiraCADeLNMeta-analysis of infrapopliteal angioplasty for chronic critical limb ischemiaJ Vasc Surg200847597598118372148
   PubMed Web of Science ®Google Scholar
• AlbersMRomitiMBrochado-NetoFCPereiraCAMeta-analysis of alternate autologous vein bypass grafts to infrapopliteal arteriesJ Vasc Surg200542344945516171586
   PubMed Web of Science ®Google Scholar
• FagliaEClericiGCaminitiMQuarantielloACurciVMorabitoAPredictive values recorded of transcutaneous oxygen tension for above-the-ankle amputation in diabetic patients with critical limb ischemiaEur J Vasc Endovasc Surg200733673173617296318
   PubMed Web of Science ®Google Scholar
• SöderströmMIArvelaEMKorhonenMInfrapopliteal percutaneous transluminal angioplasty versus bypass surgery as first-line strategies in critical leg ischemia: a propensity score analysisAnn Surg2010252576577321037432
   PubMed Web of Science ®Google Scholar
• SchaperNCAndrosGApelqvistJDiagnosis and treatment of peripheral arterial disease in diabetic patients with a foot ulcer. A progress report of the International Working Group on the Diabetic FootDiabetes Metab Res Rev201228suppl 1236237
   PubMedGoogle Scholar
• HinchliffeRJAndrosGApelqvistJA systematic review of the effectiveness of revascularization of the ulcerated foot in patients with diabetes and peripheral arterial diseaseDiabetes Metab Res Rev201228suppl 117921722271740
   PubMedGoogle Scholar
• JohnsonBLGlickmanMHBandykDFEssesGEFailure of foot salvage in patients with end-stage renal disease after surgical revascularizationJ Vasc Surg19952232802857674471
   PubMed Web of Science ®Google Scholar
• VenermoMBiancariFArvelaEThe role of chronic kidney disease as a predictor of outcome after revascularisation of the ulcerated diabetic footDiabetologia201154122971297721845468
   PubMed Web of Science ®Google Scholar
• MeloniMGiuratoLIzzoVLong term outcomes of diabetic haemodialysis patients with critical limb ischemia and foot ulcerDiabetes Res Clin Pract201611611712227321326
   PubMed Web of Science ®Google Scholar
• FerraresiRCentolaMFerliniMLong-term outcomes after angioplasty of isolated, below-the-knee arteries in diabetic patients with critical limb ischaemiaEur J Vasc Endovasc Surg200937333634219112033
   PubMed Web of Science ®Google Scholar
• GiuratoLGandiniRMeloniMPercutaneous angioplasty in diabetic patients with critical limb ischemia and chronic kidney diseaseOpen J Endocr Metab Dis201333208212
   Google Scholar
• CaravaggiCDe GiglioRPritelliCExtensive use of peripheral angioplasty, particularly infrapopliteal, in the treatment of ischaemic diabetic foot ulcers: clinical results of a multicentric study of 221 consecutive diabetic subjectsJ Intern Med2002252322523212270002
   PubMed Web of Science ®Google Scholar
• GrazianiLPiaggesiAIndications and clinical outcomes for below knee endovascular therapy: review articleCatheter Cardiovasc Interv201075343344319937784
   PubMed Web of Science ®Google Scholar
• FagliaEClericiGClerissiJLong term prognosis of diabetic patients with critical limb ischemia: a population based cohort studyDiabetes Care200932582282719223609
   PubMed Web of Science ®Google Scholar
• Weis-MüllerBTRömmlerVLippeltICritical chronic peripheral arterial disease: does outcome justify crural or pedal bypass surgery in patients with advanced age or with comorbidities?Ann Vasc Surg201125678379521641181
   PubMed Web of Science ®Google Scholar
• WerneckCCLindsay TibialTFangioplasty for limb salvage in high-risk patients and cost analysisAnn Vasc Surg200923555455919632085
   PubMed Web of Science ®Google Scholar
• PomposelliFBKansalNHamdanADA decade of experience with dorsalis pedis artery by-pass: analysis of outcome in more than 1000 casesJ Vasc Surg200337230731512563200
   PubMed Web of Science ®Google Scholar
• PomposelliFBJrMarcaccioEJGibbonsGWDorsalis pedis arterial bypass: durable limb salvage for foot ischemia in patients with diabetes mellitusJ Vasc Surg19952133753847877219
   PubMed Web of Science ®Google Scholar
• MeloniMIzzoVGiuratoLRisk of contrast induced nephropathy in diabetic patients affected by critical limb ischemia and diabetic foot ulcers treated by percutaneous transluminal angioplasty of lower limbsDiabetes Metab Res Rev2017333
   PubMed Web of Science ®Google Scholar
• FagliaEClericiGClerissiJAngioplasty for diabetic patients with failing bypass graft or residual critical ischemia after bypass graftEur J Vasc Endovasc Surg200836333133818538593
   PubMed Web of Science ®Google Scholar
• DickFDiehmNGalimanisAHusmannMSchmidliJBaumgartnerISurgical or endovascular revascularization in patients with critical limb ischemia: influence of diabetes mellitus on clinical outcomeJ Vasc Surg200745475176117306950
   PubMed Web of Science ®Google Scholar
• GandiniRChiappaRDi PrimioMRecanalization of the native artery in patients with bypass failureCardiovasc Intervent Radiol20093261146115319727939
   PubMed Web of Science ®Google Scholar
• DiehmNShangASilvestroAAssociation of cardiovascular risk factors with pattern of lower limb atherosclerosis in 2659 patients undergoing angioplastyEur J Vasc Endovasc Surg2006311596316269257
   PubMed Web of Science ®Google Scholar
• AmblerGKRadwanRHayesPDTwineCPAtherectomy for peripheral arterial diseaseCochrane Database Syst Rev20143CD006680
   Google Scholar
• SchmidtAUlrichMWinklerBAngiographic patency and clinical outcome after balloon-angioplasty for extensive infrapopliteal arterial diseaseCatheter Cardiovasc Interv20107671047105420518006
   PubMed Web of Science ®Google Scholar
• GargiuloMGiovanettiFBianchini MassoniCBypass to the ankle and foot in the era of endovascular therapy of tibial disease. Results and factors influencing the outcomeJ Cardiovasc Surg (Torino)2012553367374
   PubMed Web of Science ®Google Scholar
• BosiersMHartJPDelooseKVerbistJPeetersPEndovascular therapy as the primary approach for limb salvage in patients with critical limb ischemia: experience with 443 infrapopliteal proceduresVascular2006142636916956473
   PubMed Web of Science ®Google Scholar
• PapavassiliouVGWalkerSRBoliaAFishwickGLondonNTechniques for the endovascular management of complications following lower limb percutaneous transluminal angioplastyEur J Vasc Endovasc Surg200325212513012552472
   PubMed Web of Science ®Google Scholar
• SoderHKManninenHIJaakolaPProspective trial of infrapopliteal artery balloon angioplasty for critical limb ischemia: angiographic and clinical resultsJ Vasc Interv Radiol20001181021103110997465
   PubMed Web of Science ®Google Scholar
• GandiniRPipitoneVStefaniniMThe “Safari” technique to perform difficult subintimal infragenicular vesselsCardiovasc Intervent Radiol200730346947317295077
   PubMed Web of Science ®Google Scholar
• ManziMFusaroMCeccacciTClinical results of below-the knee intervention using pedal-plantar loop technique for the revascularization of foot arteriesJ Cardiovasc Surg (Torino)2009503331337
   PubMed Web of Science ®Google Scholar
• FusaroMAgostoniPBiondi-ZoccaiG“Trans-collateral” angioplasty for a challenging chronic total occlusion of the tibial vessels: a novel approach to percutaneous revascularization in critical lower limb ischemiaCatheter Cardiovasc Interv200871226827218327847
   PubMed Web of Science ®Google Scholar
• PalenaLMManziMExtreme below-the-knee interventions: retrograde transmetatarsal or transplantar arch access for foot salvage in challenging cases of critical limb ischemiaJ Endovasc Ther201219680581123210880
   PubMed Web of Science ®Google Scholar
• GandiniRUccioliLSpinelliAAlternative techniques for treatment of complex below-the knee arterial occlusions in diabetic patients with critical limb ischemiaCardiovasc Intervent Radiol2013361758322278664
   PubMed Web of Science ®Google Scholar
• TaylorGIPalmerJHThe vascular territories (angiosomes) of the body: experimental study and clinical applicationsBr J Plast Surg19874021131413567445
   PubMedGoogle Scholar
• AttingerCEEvansKKBulanEBlumePCooperPAngiosomes of the foot and ankle and clinical implications for limb salvage: reconstruction, incisions, and revascularizationPlast Reconstr Surg2006117suppl 7261S293S16799395
   PubMed Web of Science ®Google Scholar
• FossacecaRGuzzardiGCeriniPEndovascular treatment of diabetic foot in a selected population of patients with below-the-knee disease: is the angiosome model effective?Cardiovasc Intervent Radiol201336363764423358605
   PubMed Web of Science ®Google Scholar
• AlexandrescuVVincentGAzdadKA reliable approach to diabetic neuroischemic foot wounds: below-the-knee angiosome-oriented angioplastyJ Endovasc Ther201118337638721679080
   PubMed Web of Science ®Google Scholar
• IidaOSogaYHiranoKLong-term results of direct and indirect endovascular revascularization based on the angiosome concept in patients with critical limb ischemia presenting with isolated below-the-knee lesionsJ Vasc Surg2012552363370.e522051875
   PubMed Web of Science ®Google Scholar
• SöderströmMAlbäckABiancariFLappalainenKLepäntaloMVenermoMAngiosome-targeted infrapopliteal endovascular revascularization for treatment of diabetic foot ulcersJ Vasc Surg201357242743523219512
   PubMed Web of Science ®Google Scholar
• LejayAGeorgYTartagliaELong-term outcomes of direct and indirect below-the-knee open revascularization based on the angiosome concept in diabetic patients with critical limb ischemiaAnn Vasc Surg201328498398924333196
   PubMed Web of Science ®Google Scholar
• IzzoVMeloniMFabianoSTranscutaneous oximetry is a useful tool to highlight ischemia of the heelCardiovasc Intervent Radiol201740112012427488199
   PubMed Web of Science ®Google Scholar
• BrosiPBaumgartnerISilvestroABelow-the-knee angioplasty in patients with end-stage renal diseaseJ Endovasc Ther200512670471316363900
   PubMed Web of Science ®Google Scholar
• EdmondsMEBlundellMPMorrisMEThomasEMCottonLTWatkinsPJImproved survival of the diabetic foot: the role of a specialized foot clinicQ J Med1986602327637713774959
   PubMedGoogle Scholar
• GandiniRMerollaSScaggianteJEndovascular distal plantar venous arterialization in dialyzed patients with critical limb ischemia and posterior tibial artery occlusion: a technical note of a new frontier of Limb Salvage in a challenging subset of patientsJ Endovasc Ther201825112713229264998
   PubMed Web of Science ®Google Scholar
• Francois-FranckMNote a propos de la communication de M Raimond Petit sur la susture arterio-veneuseCompt Rend Hebd Soc Biol189648150
   Google Scholar
• MatoloNMCohenSWWolfmanEFUse of an arteriovenous fistula for treatment of the severely ischemic extremity: experimental evaluationAnn Surg19761845622625984932
   PubMed Web of Science ®Google Scholar
• UccioliLGiuratoLMeloniMComment on Hoffstad et al. diabetes, lower-extremity amputation, and death. Diabetes Care 2015;38:1852–1857Diabetes Care2016391e726696668
   PubMedGoogle Scholar
• HoffstadOMitraNWalshJMargolisDJDiabetes, lower-extremity amputation, and deathDiabetes Care201538101852185726203063
   PubMed Web of Science ®Google Scholar
• RajagopalanSMohlerERLedermanRJRegional angiogenesis with vascular endothelial growth factor in peripheral arterial disease – a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudicationCirculation2003108161933193814504183
   PubMed Web of Science ®Google Scholar
• PowellRJSimonsMMendelsohnFOResults of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemiaCirculation20081181586518559703
   PubMed Web of Science ®Google Scholar
• NikolSBaumgartnerIVan BelleETherapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critical limb ischemiaMol Ther2008165972978
   PubMed Web of Science ®Google Scholar
• KoSHBandykDFTherapeutic angiogenesis for critical limb ischemiaSemin Vasc Surg2014271233125812756
   PubMed Web of Science ®Google Scholar
• FadiniGPAgostiniCAvogaroAAutologous stem cell therapy for peripheral arterial disease meta-analysis and systematic review of the literatureAtherosclerosis20102091101719740466
   PubMed Web of Science ®Google Scholar
• LawallHBramlagePAmannBStem cell and progenitor cell therapy in peripheral artery disease. A critical appraisalThromb Haemost2010103469670920174766
   PubMed Web of Science ®Google Scholar
• LiuYXuYFangFZhangJGuoLWengZTherapeutic efficacy of stem cell-based therapy in peripheral arterial disease: a meta-analysisPLoS One2015104e012503225923119
   PubMed Web of Science ®Google Scholar
• WangZXLiDCaoJXEfficacy of autologous bone marrow mononuclear cell therapy in patients with peripheral arterial diseaseJ Atheroscler Thromb201421111183119625078066
   PubMed Web of Science ®Google Scholar
• TongersJRoncalliJGLosordoDWTherapeutic angiogenesis for critical limb ischemia – microvascular therapies coming of ageCirculation2008118191618591450
   PubMed Web of Science ®Google Scholar
• Peeters WeemSMTeraaMde BorstGJVerhaarMCMollFLBone marrow derived cell therapy in critical limb ischemia: a meta-analysis of randomized placebo controlled trialsEur J Vasc Endovasc Surg201550677578326460286
   PubMed Web of Science ®Google Scholar
• TeraaMSprengersRWvan der GraafYPetersCEMollFLVerhaarMCAutologous bone marrow-derived cell therapy in patients with critical limb ischemia: a meta-analysis of randomized controlled clinical trialsAnn Surg2013258692292923426345
   PubMed Web of Science ®Google Scholar
• GremmelsHTeraaMQuaxPHden OudenKFledderusJOVerhaarMCNeovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controlsMol Ther201422111960197025174586
   PubMed Web of Science ®Google Scholar
• CatrinaSBOkamotoKPereiraTBrismarKPoellingerLHyperglycemia regulates hypoxia-inducible factor 1-alpha protein stability and functionDiabetes200453123226323215561954
   PubMed Web of Science ®Google Scholar
• UccioliLIzzoVMeloniMVainieriERuotoloVGiuratoLNon-healing foot ulcers in diabetic patients: general and local interfering conditions and management options with advanced wound dressingsJ Wound Care2015244 suppl354225853647
   PubMed Web of Science ®Google Scholar
• BuschmannISchaperWArteriogenesis versus angiogenesis: two mechanisms of vessels growthNews Physiol Sci19991412112511390835
   PubMedGoogle Scholar
• HalsteadAEVaughanRTArteriovenous anastomosis in the treatment of gangrene of the extremitiesSurg Gynecol Obstet1912141
   Google Scholar