References
- GoASBaumanMAColeman KingSMAn effective approach to high blood pressure control: A science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and PreventionJ Am Coll Cardiol201463121230123824246165
- KostisJBCabreraJChengJQAssociation between chlorthalidone treatment of systolic hypertension and long-term survivalJAMA2011306232588259322187278
- McalisterFAWilkinsKJoffresMChanges in the rates of awareness, treatment and control of hypertension in Canada over the past two decadesCMAJ201118391007101321576297
- TuKCampbellNRCDuong-HuaMMcalisterFAHypertension management in the elderly has improved - Ontario prescribing trends, 1994–2002Hypertension2005451113111815851629
- OliverasAArmarioPLucasSde La SierraACOMBICONTROL Study InvestigatorsBlood pressure control is similar in treated hypertensive patients with optimal or with high-normal albuminuriaAm J Hypertens20142791185119024646879
- Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of HypertensionJ Clin Hypertens2014161426
- SPRINT Research GroupWrightJTWilliamsonJDA randomized trial of intensive versus standard blood-pressure controlN Engl J Med2015373222103211626551272
- ACCORD Study GroupCushmanWCEvansGWEffects of intensive blood-pressure control in type 2 diabetes mellitusN Engl J Med2010362171575158520228401
- BurgessEEplerenone in hypertensionExpert Opin Pharmacother20045122573258115571474
- JansenPMFrenkelWJvan den BornBJDeterminants of blood pressure reduction by eplerenone in uncontrolled hypertensionJ Hypertens201331240441323249826
- KarnsADBralJMHartmanDPeppardTSchumacherCStudy of aldosterone synthase inhibition as an add-on therapy in resistant hypertensionJ Clin Hypertens2013153186192
- WilliamsBMacdonaldTMMorantSSpironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trialLancet2015386100082059206826414968
- BombackASKlemmerPJThe incidence and implications of aldosterone breakthroughNat Clin Pract Nephrol20073948649217717561
- ZannadFMcMurrayJJKrumHEplerenone in patients with systolic heart failure and mild symptomsN Engl J Med20113641112121073363
- PittBZannadFRemmeWJThe effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study InvestigatorsN Engl J Med19993411070971710471456
- PittBRemmeWZannadFEplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarctionN Engl J Med2003348141309132112668699
- BatterinkJStablerSNTejaniAMFowkesCTSpironolactone for hypertensionCochrane Database Syst Rev20108CD00816920687095
- CroomKFPerryCMEplerenone: a review of its use in essential hypertensionAm J Cardiovasc Drugs200551516915631538
- Rafestin-OblinMERudolphAFaggartJEplerenone: a selective aldosterone blockerJ Hypertens200321Suppl 4202
- de GasparoMJossURamjouéHPThree new epoxy-spirolactone derivatives: characterization in vivo and in vitroJ Pharmacol Exp Ther198724026506562949071
- GarthwaiteSMMcMahonEGThe evolution of aldosterone antagonistsMol Cell Endocrinol20042171–2273115134797
- Pfizer Canada IncINSPRA Product Monograph2014
- YamajiMTsutamotoTKawaharaCNishiyamaKYamamotoTFujiiMHorieMEffect of eplerenone versus spironolactone on cortisol and hemoglobin A1(c) levels in patients with chronic heart failureAm Heart J2010160591592121095280
- LainscakMPellicciaFRosanoGSafety profile of mineralocorticoid receptor antagonists: spironolactone and eplerenoneInt J Cardiol2015200252926404748
- JankowskaEABielBMajdaJAnabolic deficiency in men with chronic heart failure: prevalence and detrimental impact on survivalCirculation20061141829183717030678
- Pfizer IncINSPRA US Package Insert2016
- PellicciaFPattiGRosanoGGrecoCGaudioCEfficacy and safety of eplerenone in the management of mild to moderate arterial hypertension: systematic review and meta-analysisInt J Cardiol2014177121922825499383
- TamTSWuMHMassonSCEplerenone for hypertensionCochrane Database Syst Rev20172CD00899628245343
- PrestonRAMatersonBJRedaDJWilliamsDWPlacebo-associated blood pressure response and adverse effects in the treatment of hypertension: observations from a Department of Veterans Affairs Cooperative StudyArch Intern Med2000160101449145410826457
- GuQBurtVLDillonCFYoonSTrends in antihypertensive medication use and blood pressure control among United States adults with hypertension. The National Health and Nutrition Evaluation Survey, 2001–2010Circulation2012126172105211423091084
- WeinbergerMHEplerenone, a selective aldosterone blocker, in mild-to-moderate hypertensionAm J Hypertens20021570971612160194