Clinical and Diagnostic Value of Highly Sensitive Cardiac Troponins in Arterial Hypertension

References

• Kobayashi T, Jin L, de Tombe PP. Cardiac thin filament regulation. Pflugers Arch. 2008;457(1):37–46. doi:10.1007/s00424-008-0511-8
   PubMed Web of Science ®Google Scholar
• Tobacman LS. Thin filament-mediated regulation of cardiac contraction. Annu Rev Physiol. 1996;58:447–481. doi:10.1146/annurev.ph.58.030196.002311
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Karslyan LS, Duplyakov DV. Non-Coronarogenic Causes of Increased Cardiac Troponins in Clinical Practice. J Clin Practice. 2019;10(4):81–93. doi:10.17816/clinpract16309
   Google Scholar
• Duplyakov DV, Chaulin AM. Mutations of heart troponines, associated with cardiomyopathies. Kardiologiya. 2019;7(3):8–17. doi:10.24411/2309-1908-2019-13001
   Google Scholar
• Yotti R, Seidman CE, Seidman JG. Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies. Annu Rev Genomics Hum Genet. 2019;20:129–153. doi:10.1146/annurev-genom-083118-015306
   PubMed Web of Science ®Google Scholar
• Marques MA, de Oliveira GA. Cardiac Troponin and Tropomyosin: structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy Phenotype. Front Physiol. 2016;7:429. doi:10.3389/fphys.2016.00429
   PubMed Web of Science ®Google Scholar
• Thygesen K, Alpert JS, Jaffe AS, et al. Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction. Fourth Universal Definition of Myocardial Infarction (2018). Glob Heart. 2018;13(4):305–338. doi:10.1016/j.gheart.2018.08.004
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Duplyakov DV. Biomarkers of acute myocardial infarction: diagnostic and prognostic value. Part 1. J Clin Practice. 2020;11(3):75–84. doi:10.17816/clinpract34284
   Google Scholar
• Chaulin A. Cardiac Troponins: contemporary Biological Data and New Methods of Determination. Vasc Health Risk Manag. 2021;17:299–316. doi:10.2147/VHRM.S300002
   PubMed Web of Science ®Google Scholar
• Shah A, Griffiths M, Lee KK, et al. High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women. BMJ. 2015;350:g7873. doi:10.1136/bmj.g7873
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Karslyan LS, Bazyuk EV, et al. Clinical and diagnostic value of cardiac markers in human biological fluids. Kardiologiia. 2019;59(11):66–75. doi:10.18087/cardio.2019.11.n414 In Russian.
   PubMed Web of Science ®Google Scholar
• Katus HA, Looser S, Hallermayer K, et al. Development and in vitro characterization of a new immunoassay of cardiac troponin T. Clin Chem. 1992;38(3):386‐393. doi:10.1093/clinchem/38.3.386
   Web of Science ®Google Scholar
• Cummins B, Auckland ML, Cummins P. Cardiac-specific troponin-I radioimmunoassay in the diagnosis of acute myocardial infarction. Am Heart J. 1987;113(6):1333‐1344. doi:10.1016/0002-8703(87)90645-4
   PubMed Web of Science ®Google Scholar
• Kozinski M, Krintus M, Kubica J, Sypniewska G. High-sensitivity cardiac troponin assays: from improved analytical performance to enhanced risk stratification. Crit Rev Clin Lab Sci. 2017;54(3):143–172. doi:10.1080/10408363.2017.1285268
   PubMed Web of Science ®Google Scholar
• Brinkmann C, Schofer J. Allgemeine Definition des Myokardinfarkts 2018: was ist neu? [4th universal definition of myocardial infarction 2018: what is new?]. Herz. 2018;43(8):681–688. doi:10.1007/s00059-018-4763-6
   PubMed Web of Science ®Google Scholar
• Löfberg M, Tähtelä R, Härkönen M, Somer H. Myosin heavy-chain fragments and cardiac troponins in the serum in rhabdomyolysis. Diagnostic specificity of new biochemical markers. Arch Neurol. 1995;52(12):1210–1214. doi:10.1001/archneur.1995.00540360090020
   PubMedGoogle Scholar
• Müller-Bardorff M, Hallermayer K, Schröder A, et al. Improved troponin T ELISA specific for cardiac troponin T isoform: assay development and analytical and clinical validation. Clin Chem. 1997;43(3):458–466. doi:10.1093/clinchem/43.3.458
   PubMed Web of Science ®Google Scholar
• Siegel AJ, Lewandrowski KB, Strauss HW, Fischman AJ, Yasuda T. Normal post-race antimyosin myocardial scintigraphy in asymptomatic marathon runners with elevated serum creatine kinase MB isoenzyme and troponin T levels. Evidence against silent myocardial cell necrosis. Cardiology. 1995;86(6):451–456. doi:10.1159/000176922
   PubMed Web of Science ®Google Scholar
• Apple FS. Tissue specificity of cardiac troponin I, cardiac troponin T and creatine kinase-MB. Clin Chim Acta. 1999;284(2):151–159. doi:10.1016/s0009-8981(99)00077-7
   PubMed Web of Science ®Google Scholar
• Apple FS, Ricchiuti V, Voss EM, Anderson PA, Ney A, Odland M. Expression of cardiac troponin T isoforms in skeletal muscle of renal disease patients will not cause false-positive serum results by the second generation cardiac troponin T assay. Eur Heart J. 1998;19(Suppl):N:N30–3.
   PubMedGoogle Scholar
• Ricchiutti V, Apple FS. RNA expression of cardiac troponin T isoforms in diseased human skeletal muscle. Clin Chem. 1999;45(12):2129–2135. doi:10.1093/clinchem/45.12.2129
   PubMed Web of Science ®Google Scholar
• Messner B, Baum H, Fischer P, et al. Expression of messenger RNA of the cardiac isoforms of troponin T and I in myopathic skeletal muscle. Am J Clin Pathol. 2000;114(4):544–549. doi:10.1309/8KCL-UQRF-6EEL-36XK
   PubMed Web of Science ®Google Scholar
• McLaurin MD, Apple FS, Voss EM, Herzog CA, Sharkey SW. Cardiac troponin I, cardiac troponin T, and creatine kinase MB in dialysis patients without ischemic heart disease: evidence of cardiac troponin T expression in skeletal muscle. Clin Chem. 1997;43(6 Pt 1):976–982. doi:10.1093/clinchem/43.6.976
   PubMed Web of Science ®Google Scholar
• Jaffe AS, Vasile VC, Milone M, Saenger AK, Olson KN, Apple FS. Diseased skeletal muscle: a noncardiac source of increased circulating concentrations of cardiac troponin T. J Am Coll Cardiol. 2011;58(17):1819–1824. doi:10.1016/j.jacc.2011.08.026
   PubMed Web of Science ®Google Scholar
• Schmid J, Liesinger L, Birner-Gruenberger R, et al. Elevated Cardiac Troponin T in Patients With Skeletal Myopathies. J Am Coll Cardiol. 2018;71(14):1540–1549. doi:10.1016/j.jacc.2018.01.070
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Duplyakov DV. Increased cardiac troponins, not associated with acute coronary syndrome. Part 1. Kardiologiya. 2019;7(2):13–23. doi:10.24411/2309-1908-2019-12002
   Google Scholar
• Chaulin AM, Duplyakov DV. Increased cardiac troponins, not associated with acute coronary syndrome. Part 2. Kardiologiya. 2019;7(2):24–35. doi:10.24411/2309-1908-2019-12003
   Google Scholar
• Chaulin AM, Svechkov NA, Volkova SL, Grigoreva YV. Diagnostic value of cardiac troponins in elderly patients without myocardial infarction. Modern problems sci educ. 2020;6. doi:10.17513/spno.30302
   Google Scholar
• Chaulin AM, Karslyan LS, Grigorieva EV, Nurbaltaeva DA, Duplyakov DV. Metabolism of cardiac troponins (literature review). Complex Issues Cardiovascular Dis. 2019;8(4):103–115. doi:10.17802/2306-1278-2019-8-4-103-115
   Google Scholar
• Zhao H, Lin Q, Huang L, et al. Ultrasensitive chemiluminescence immunoassay with enhanced precision for the detection of cTnI amplified by acridinium ester-loaded microspheres and internally calibrated by magnetic fluorescent nanoparticles. Nanoscale. 2021;13(5):3275–3284. doi:10.1039/d0nr08008j
   PubMed Web of Science ®Google Scholar
• Garcia-Osuna A, Gaze D, Grau-Agramunt M, et al. Ultrasensitive quantification of cardiac troponin I by a single molecule counting method: analytical validation and biological features. Clin Chim Acta. 2018;486:224‐231. doi:10.1016/j.cca.2018.08.015
   PubMed Web of Science ®Google Scholar
• Bohn MK, Higgins V, Kavsak P, Hoffman B, Adeli K. High-Sensitivity Generation 5 Cardiac Troponin T Sex- and Age-Specific 99th Percentiles in the CALIPER Cohort of Healthy Children and Adolescents. Clin Chem. 2019;65(4):589–591. doi:10.1373/clinchem.2018.299156
   PubMed Web of Science ®Google Scholar
• Widera C, Giannitsis E, Mueller-Hennessen M, et al. Diagnostic and prognostic value of sex- and age-specific cutpoints for high-sensitivity Troponin T in non-ST-elevation acute coronary syndrome. Int J Cardiol. 2019;275:13–19. doi:10.1016/j.ijcard.2018.10.027
   PubMed Web of Science ®Google Scholar
• Monneret D, Gellerstedt M, Bonnefont-Rousselot D. Determination of age- and sex-specific 99th percentiles for high-sensitive troponin T from patients: an analytical imprecision- and partitioning-based approach. Clin Chem Lab Med. 2018;56(5):818–829. doi:10.1515/cclm-2017-0256
   PubMed Web of Science ®Google Scholar
• Klinkenberg LJJ, Wildi K, van der Linden N, et al. Diurnal rhythm of cardiac troponin: consequences for the diagnosis of acute myocardial infarction. Clin Chem. 2016;62(12):1602–1611. doi:10.1373/clinchem.2016.257485
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Duplyakova PD, Duplyakov DV. Circadian rhythms of cardiac troponins: mechanisms and clinical significance. Russ J Cardiol. 2020;25(3):4061. doi:10.15829/1560-4071-2020-4061
   Google Scholar
• Chaulin AM, Duplyakov DV. High-sensitivity cardiac troponins: circadian rhythms. Cardiovasc Ther Prev. 2021;20(1):2639. doi:10.15829/1728-8800-2021-2639
   Google Scholar
• Chaulin AM, Duplyakov DV. Environmental factors and cardiovascular diseases. Hygiene Sanitation. 2021;100(3):223–228. doi:10.47470/0016-9900-2021-100-3-223-228
   Google Scholar
• van der Linden N, Cornelis T, Klinkenberg LJJ, et al. Strong diurnal rhythm of troponin T, but not troponin I, in a patient with renal dysfunction. Int J Cardiol. 2016;221:287–288. doi:10.1016/j.ijcard.2016.06.268
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Duplyakov DV. On the potential effect of circadian rhythms of cardiac troponins on the diagnosis of acute myocardial infarction. Signa Vitae. 2021;17(3):79–84. doi:10.22514/sv.2021.050
   Web of Science ®Google Scholar
• Chaulin AM, Duplyakov DV. Comorbidity in chronic obstructive pulmonary disease and cardiovascular disease. Cardiovascular Therapy Prevent. 2021;20(3):2539. doi:10.15829/1728-8800-2021-2539
   Google Scholar
• Sigurdardottir FD, Lyngbakken MN, Holmen OL, et al. Relative Prognostic Value of Cardiac Troponin I and C-Reactive Protein in the General Population (from the Nord-Trøndelag Health [HUNT] Study). Am J Cardiol. 2018;121(8):949–955. doi:10.1016/j.amjcard.2018.01.004
   PubMed Web of Science ®Google Scholar
• Clerico A, Padoan A, Zaninotto M, Passino K, Plebani M. Clinical relevance of biological variation of cardiac troponins. Clin Chem Lab Med. 2020. doi:10.1515/cclm-2020-1433
   Web of Science ®Google Scholar
• Postigo A, Vernooij RWM, Fernández-Avilés F, Martínez-Sellés M. Cardiac troponin and infective endocarditis prognosis: a systematic review and meta-analysis. Eur Heart J Acute Cardiovasc Care. 2021;10(3):356–366. doi:10.1093/ehjacc/zuab008
   PubMed Web of Science ®Google Scholar
• Weckbach LT, Curta A, Bieber S, et al. Myocardial Inflammation and Dysfunction in COVID-19-Associated Myocardial Injury. Circ Cardiovasc Imaging. 2021;14(1):e012220. doi:10.1161/CIRCIMAGING.120.011713
   PubMed Web of Science ®Google Scholar
• Gommans DHF, Cramer GE, Fouraux MA, et al. Usefulness of High-Sensitivity Cardiac Troponin T to Predict Long-Term Outcome in Patients with Hypertrophic Cardiomyopathy. Am J Cardiol. 2021;152:120–124. doi:10.1016/j.amjcard.2021.04.040
   PubMed Web of Science ®Google Scholar
• Wang K, Zelnick LR, Anderson A, et al. Cardiac Biomarkers and Risk of Mortality in CKD (the CRIC Study). Kidney Int Rep. 2020;5(11):2002–2012. doi:10.1016/j.ekir.2020.08.028
   PubMed Web of Science ®Google Scholar
• Chaudary N, Geraci SA. Prognostic value of cardiac-specific troponins in chronic obstructive pulmonary disease exacerbations: a systematic review. J Miss State Med Assoc. 2014;55(2):40–44.
   PubMedGoogle Scholar
• Chaulin AM, Abashina OE, Duplyakov DV. Pathophysiological mechanisms of cardiotoxicity in chemotherapeutic agents. Russian Open Med J. 2020;9:e0305. doi:10.15275/rusomj.2020.0305
   Web of Science ®Google Scholar
• Chaulin AM, Duplyakov DV. Arrhythmogenic effects of doxorubicin. Complex Issues Cardiovascular Dis. 2020;9(3):69–80. doi:10.17802/2306-1278-2020-9-3-69-80
   Google Scholar
• Samaha E, Brown J, Brown F, et al. High-sensitivity cardiac troponin T increases after stress echocardiography. Clin Biochem. 2019;63:18–23. doi:10.1016/j.clinbiochem.2018.11.013
   PubMed Web of Science ®Google Scholar
• Li F, Hopkins WG, Wang X, et al. Moderators and Reference Limits of Exercise-Induced Elevation of Cardiac Troponin T in Athletes: a Systematic Review and Meta-Analysis. Front Physiol. 2021;12:651851. doi:10.3389/fphys.2021.651851
   PubMed Web of Science ®Google Scholar
• Caligiuri SP, Austria JA, Pierce GN. Alarming Prevalence of Emergency Hypertension Levels in the General Public Identified by a Hypertension Awareness Campaign. Am J Hypertens. 2017;30(3):236–239. doi:10.1093/ajh/hpw136
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Grigorieva Y, Pavlova TV, Duplyakov DV. Diagnostic significance of complete blood count in cardiovascular patients; Samara State Medical University. Russian J Cardiol. 2020;25(12):3923. doi:10.15829/1560-4071-2020-3923
   Google Scholar
• Lawes CM, Vander Hoorn S, Rodgers A. International Society of Hypertension. Global burden of blood-pressure-related disease, 2001. Lancet. 2008;371(9623):1513–1518. doi:10.1016/S0140-6736(08)60655-8
   PubMed Web of Science ®Google Scholar
• World Health Organization. A Global Brief on Hypertension: Silent Killer, Global Public Health Crisis. 2 ed. Geneva, Switzerland: World Health Organization; 2013. https://apps.who.int/iris/bitstream/handle/10665/79059/WHO_DCO_WHD_2013.2_rus.pdf?sequence=5&isAllowed=y. Accessed July 8, 2021.
   Google Scholar
• Lindner G, Pfortmueller CA, Braun CT, Exadaktylos AK. Non-acute myocardial infarction-related causes of elevated high-sensitive troponin T in the emergency room: a cross-sectional analysis. Intern Emerg Med. 2014;9(3):335–339. doi:10.1007/s11739-013-1030-y
   PubMed Web of Science ®Google Scholar
• Long B, Long DA, Tannenbaum L, Koyfman A. An emergency medicine approach to troponin elevation due to causes other than occlusion myocardial infarction. Am J Emerg Med. 2020;38(5):998–1006. doi:10.1016/j.ajem.2019.12.007
   PubMed Web of Science ®Google Scholar
• Masri W, Le Guillou E, Hamdi E, et al. Troponin elevation in other conditions than acute coronary syndromes. Ann Biol Clin (Paris). 2017;75(4):411–419. doi:10.1684/abc.2017.1262
   PubMed Web of Science ®Google Scholar
• Stabouli S, Kotsis V, Rizos Z, et al. Left ventricular mass in normotensive, prehypertensive and hypertensive children and adolescents. Pediatr Nephrol. 2009;24(8):1545–1551. doi:10.1007/s00467-009-1165-2
   PubMed Web of Science ®Google Scholar
• McEvoy JW, Chen Y, Nambi V, et al. High-Sensitivity Cardiac Troponin T and Risk of Hypertension. Circulation. 2015;132(9):825–833. doi:10.1161/CIRCULATIONAHA.114.014364
   PubMed Web of Science ®Google Scholar
• de Lemos JA, Drazner MH, Omland T, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA. 2010;304(22):2503–2512. doi:10.1001/jama.2010.1768
   PubMed Web of Science ®Google Scholar
• Uçar H, Gür M, Kivrak A, et al. High-sensitivity cardiac troponin T levels in newly diagnosed hypertensive patients with different left ventricle geometry. Blood Press. 2014;23(4):240–247. doi:10.3109/08037051.2013.840429
   PubMed Web of Science ®Google Scholar
• Harvell B, Henrie N, Ernst AA, et al. The meaning of elevated troponin I levels: not always acute coronary syndromes. Am J Emerg Med. 2016;34(2):145–148. doi:10.1016/j.ajem.2015.09.037
   PubMed Web of Science ®Google Scholar
• Afonso L, Bandaru H, Rathod A, et al. Prevalence, determinants, and clinical significance of cardiac troponin-I elevation in individuals admitted for a hypertensive emergency. J Clin Hypertens. 2011;13(8):551–556. doi:10.1111/j.1751-7176.2011.00476.x
   PubMed Web of Science ®Google Scholar
• Papadopoulos DP, Sanidas EA, Viniou NA, et al. Cardiovascular hypertensive emergencies. Curr Hypertens Rep. 2015;17(2):5. doi:10.1007/s11906-014-0515-z
   PubMed Web of Science ®Google Scholar
• Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: a Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2018;71(19):e127–e248. doi:10.1016/j.jacc.2017.11.006
   PubMed Web of Science ®Google Scholar
• Acosta G, Amro A, Aguilar R, et al. Clinical Determinants of Myocardial Injury, Detectable and Serial Troponin Levels among Patients with Hypertensive Crisis. Cureus. 2020;12(1):e6787. doi:10.7759/cureus.6787
   PubMed Web of Science ®Google Scholar
• Pattanshetty DJ, Bhat PK, Aneja A, Pillai DP. Elevated troponin predicts long-term adverse cardiovascular outcomes in hypertensive crisis: a retrospective study. J Hypertens. 2012;30(12):2410–2415. doi:10.1097/HJH.0b013e3283599b4f
   PubMed Web of Science ®Google Scholar
• Talha AM, Torres C, Del Cid J, Khan M, Rasool W, Aijaz T. The prognostic significance of highly sensitive cardiac troponin i elevation in patients presenting with hypertensive crisis. Circulation. 2019;140:A16333.
   Web of Science ®Google Scholar
• Omondi A, Villablanca P, Kargoli F, et al. Prevalence and prognostic significance of cardiac troponin-T elevation in patients admitted with hypertensive crises. JACC. 2017;69:1803. doi:10.1016/S0735-1097(17)35192-6
   Google Scholar
• Cheng W, Li B, Kajstura J, et al. Stretch-induced programmed myocyte cell death. J Clin Invest. 1995;96(5):2247–2259. doi:10.1172/JCI118280
   PubMed Web of Science ®Google Scholar
• Singh K, Communal C, Sawyer DB, Colucci WS. Adrenergic regulation of myocardial apoptosis. Cardiovasc Res. 2000;45(3):713–719. doi:10.1016/s0008-6363(99)00370-3
   PubMed Web of Science ®Google Scholar
• Singh K, Xiao L, Remondino A, Sawyer DB, Colucci WS. Adrenergic regulation of cardiac myocyte apoptosis. J Cell Physiol. 2001;189(3):257–265. doi:10.1002/jcp.10024
   PubMed Web of Science ®Google Scholar
• Dalal S, Connelly B, Singh M, Singh K. NF2 signaling pathway plays a pro-apoptotic role in β-adrenergic receptor stimulated cardiac myocyte apoptosis. PLoS One. 2018;13(4):e0196626. doi:10.1371/journal.pone.0196626
   PubMed Web of Science ®Google Scholar
• Weil BR, Suzuki G, Young RF, Iyer V, Canty JM. Troponin Release and Reversible Left Ventricular Dysfunction After Transient Pressure Overload. J Am Coll Cardiol. 2018;71(25):2906–2916. doi:10.1016/j.jacc.2018.04.029
   PubMed Web of Science ®Google Scholar
• Ruwhof C, van der Laarse A. Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways. Cardiovasc Res. 2000;47(1):23–37. doi:10.1016/s0008-6363(00)00076-6
   PubMed Web of Science ®Google Scholar
• van der Wees CG, Bax WH, van der Valk EJ, van der Laarse A. Integrin stimulation induces calcium signalling in rat cardiomyocytes by a NO-dependent mechanism. Pflugers Arch. 2006;451(4):588–595. doi:10.1007/s00424-005-1402-x
   PubMed Web of Science ®Google Scholar
• Kandasamy AD, Chow AK, Ali MA, Schulz R. Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix. Cardiovasc Res. 2010;85(3):413–423. doi:10.1093/cvr/cvp268
   PubMed Web of Science ®Google Scholar
• Wang W, Schulze CJ, Suarez-Pinzon WL, Dyck JR, Sawicki G, Schulz R. Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation. 2002;106(12):1543–1549. doi:10.1161/01.cir.0000028818.33488.7b
   PubMed Web of Science ®Google Scholar
• Feng J, Schaus BJ, Fallavollita JA, Lee TC, Canty JM. Preload induces troponin I degradation independently of myocardial ischemia. Circulation. 2001;103(16):2035–2037. doi:10.1161/01.cir.103.16.2035
   PubMed Web of Science ®Google Scholar
• Maekawa A, Lee JK, Nagaya T, et al. Overexpression of calpastatin by gene transfer prevents troponin I degradation and ameliorates contractile dysfunction in rat hearts subjected to ischemia/reperfusion. J Mol Cell Cardiol. 2003;35(10):1277–1284. doi:10.1016/s0022-2828(03)00238-4
   PubMed Web of Science ®Google Scholar
• Katrukha IA, Kogan AE, Vylegzhanina AV, et al. Thrombin-Mediated Degradation of Human Cardiac Troponin T. Clin Chem. 2017;63(6):1094–1100. doi:10.1373/clinchem.2016.266635
   PubMed Web of Science ®Google Scholar
• van den Born BJ, Löwenberg EC, van der Hoeven NV, et al. Endothelial dysfunction, platelet activation, thrombogenesis and fibrinolysis in patients with hypertensive crisis. J Hypertens. 2011;29(5):922–927. doi:10.1097/HJH.0b013e328345023d
   PubMed Web of Science ®Google Scholar
• Derhaschnig U, Testori C, Riedmueller E, Aschauer S, Wolzt M, Jilma B. Hypertensive emergencies are associated with elevated markers of inflammation, coagulation, platelet activation and fibrinolysis. J Hum Hypertens. 2013;27(6):368–373. doi:10.1038/jhh.2012.53
   PubMed Web of Science ®Google Scholar
• Bleier J, Vorderwinkler KP, Falkensammer J, et al. Different intracellular compartmentations of cardiac troponins and myosin heavy chains: a causal connection to their different early release after myocardial damage. Clin Chem. 1998;44(9):1912–1918. doi:10.1093/clinchem/44.9.1912
   PubMed Web of Science ®Google Scholar
• Lazzarino AI, Hamer M, Gaze D, Collinson P, Steptoe A. The association between cortisol response to mental stress and high sensitivity cardiac troponin T plasma concentration in healthy adults. J Am Coll Cardiol. 2013;62(18):1694–1701. doi:10.1016/j.jacc.2013.05.070
   PubMed Web of Science ®Google Scholar
• Richardson AJ, Leckie T, Watkins ER, et al. Post marathon cardiac troponin T is associated with relative exercise intensity. J Sci Med Sport. 2018;21(9):880–884. doi:10.1016/j.jsams.2018.02.005
   PubMed Web of Science ®Google Scholar
• Hessel MH, Atsma DE, van der Valk EJ, Bax WH, Schalij MJ, van der Laarse A. Release of cardiac troponin I from viable cardiomyocytes is mediated by integrin stimulation. Pflugers Arch. 2008;455(6):979–986. doi:10.1007/s00424-007-0354-8
   PubMed Web of Science ®Google Scholar
• deFilippi C, Seliger SL, Kelley W, et al. Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome. Clin Chem. 2012;58(9):1342–1351. doi:10.1373/clinchem.2012.185322
   PubMed Web of Science ®Google Scholar
• Diris JH, Hackeng CM, Kooman JP, Pinto YM, Hermens WT, van Dieijen-visser MP. Impaired renal clearance explains elevated troponin T fragments in hemodialysis patients. Circulation. 2004;109(1):23–25. doi:10.1161/01.CIR.0000109483.45211.8F
   PubMed Web of Science ®Google Scholar
• Di Lullo L, Barbera V, Santoboni A, et al. Malattia renale cronica e sindrome coronarica acuta: il ruolo della troponina [Troponins and chronic kidney disease]. G Ital Nefrol. 2015;32(4):254.
   Google Scholar
• Dubin RF, Li Y, He J; CRIC Study Investigators, et al. Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC). BMC Nephrol. 2013;14:229. doi:10.1186/1471-2369-14-229
   PubMed Web of Science ®Google Scholar
• Ziebig R, Lun A, Hocher B, et al. Renal elimination of troponin T and troponin I. Clin Chem. 2003;49(7):1191–1193. doi:10.1373/49.7.1191
   PubMed Web of Science ®Google Scholar
• Maruta T, Li T, Morrissey J, et al. 252: urinary Cardiac Troponin I is Detectable in Patients with Myocardial Injury Using a High-Sensitive Immunoassay. Crit Care Med. 2012;40:1–328. doi:10.1097/01.ccm.0000424470.26633.42
   PubMed Web of Science ®Google Scholar
• Pervan P, Svagusa T, Prkacin I, Savuk A, Bakos M, Perkov S. Urine high sensitive Troponin I measuring in patients with hypertension. Signa Vitae. 2017;13:62–64. doi:10.22514/SV133.062017.13
   Google Scholar
• Muslimovic A, Fridén V, Tenstad O, et al. The Liver and Kidneys mediate clearance of cardiac troponin in the rat. Sci Rep. 2020;10(1):6791. doi:10.1038/s41598-020-63744-8
   PubMed Web of Science ®Google Scholar
• Kostyukevich OI. Arterial hypertension and liver diseases: in search of a compromise. Russian Med J. 2011;19(5):338–342.
   Google Scholar
• Shah AS, Chin CW, Vassiliou V, et al. Left ventricular hypertrophy with strain and aortic stenosis. Circulation. 2014;130(18):1607–1616. doi:10.1161/CIRCULATIONAHA.114.011085
   PubMed Web of Science ®Google Scholar
• Shah AS, Griffiths M, Lee KK, et al. High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women: prospective cohort study. BMJ. 2015;350:g7873. doi:10.1136/bmj.g7873
   PubMed Web of Science ®Google Scholar
• Gore MO, Seliger SL, Defilippi CR, et al. Age- and sex-dependent upper reference limits for the high-sensitivity cardiac troponin T assay. J Am Coll Cardiol. 2014;63(14):1441–1448. doi:10.1016/j.jacc.2013.12.032
   PubMed Web of Science ®Google Scholar
• High-Sensitivity Cardiac Troponin I and T Assay Analytical Characteristics Designated by Manufacturer IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB). Available from: https://www.ifcc.org/media/478231/high-sensitivity-cardiac-troponin-i-and-t-assay-analytical-characteristics-designated-by-manufacturer-v122019.pdf. Accessed July 8, 2021.
   Google Scholar
• Morrow DA, Cannon CP, Jesse RL, et al.; National Academy of Clinical Biochemistry. National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes. Circulation. 2007;115(13):e356–75. doi:10.1161/CIRCULATIONAHA.107.182882
   PubMedGoogle Scholar
• Chaulin AM, Abashina OE, Duplyakov DV. High-sensitivity cardiac troponins: detection and central analytical characteristics. Cardiovascular Therapy Prevent. 2021;20(2):2590. doi:10.15829/1728-8800-2021-2590
   Google Scholar
• Jeremias A, Gibson CM. Narrative review: alternative causes for elevated cardiac troponin levels when acute coronary syndromes are excluded. Ann Intern Med. 2005;142(9):786–791. doi:10.7326/0003-4819-142-9-200505030-00015
   PubMed Web of Science ®Google Scholar
• Horwich TB, Patel J, MacLellan WR, Fonarow GC. Cardiac troponin I is associated with impaired hemodynamics, progressive left ventricular dysfunction, and increased mortality rates in advanced heart failure. Circulation. 2003;108(7):833–838. doi:10.1161/01.CIR.0000084543.79097.34
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Duplyakova PD, Bikbaeva GR, Tukhbatova AA, Grigorieva EV, Duplyakov DV. Concentration of high-sensitivity cardiac troponin I in the oral fluid in patients with acute myocardial infarction: a pilot study. Russian J Cardiol. 2020;25(12):3814. doi:10.15829/1560-4071-2020-3814
   Google Scholar
• Chaulin AM, Karslyan LS, Bazyuk EV, Nurbaltaeva DA, Duplyakov DV. Clinical and Diagnostic Value of Cardiac Markers in Human Biological Fluids. Kardiologiia. 2019;59(11):66–75. doi:10.18087/cardio.2019.11.n414
   PubMed Web of Science ®Google Scholar
• Chaulin AM, Duplyakov DV. Increased natriuretic peptides not associated with heart failure. Russian J Cardiol. 2020;25:4140. doi:10.15829/1560-4071-2020-4140
   Google Scholar
• Joharimoghadam A, Tajdini M, Bozorgi A. Salivary B-type natriuretic peptide: a new method for heart failure diagnosis and follow-up. Kardiol Pol. 2017;75(1):71–77. doi:10.5603/KP.a2016.0097
   PubMed Web of Science ®Google Scholar
• Chen JY, Lee SY, Li YH, Lin CY, Shieh MD, Ciou DS. Urine High-Sensitivity Troponin I Predict Incident Cardiovascular Events in Patients with Diabetes Mellitus. J Clin Med. 2020;9(12):3917. doi:10.3390/jcm9123917
   PubMed Web of Science ®Google Scholar
• Potkonjak AM, Sabolović Rudman S, Nikolac Gabaj N, et al. Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia. Med Hypotheses. 2020;144:110252. doi:10.1016/j.mehy.2020.110252
   PubMed Web of Science ®Google Scholar