A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now?

References

• Tsao CW, Aday AW, Almarzooq ZI, et al. Heart disease and stroke statistics-2022 update: a report from the American heart association. Circulation. 2022;145(8):e153–e639.
   PubMed Web of Science ®Google Scholar
• Fischer NM, Pallazola VA, Xun H, Cainzos-Achirica M, Michos ED. The evolution of the heart-healthy diet for vascular health: a walk through time. Vasc Med. 2020;25(2):184–193.
   PubMed Web of Science ®Google Scholar
• Menotti A, Puddu PE. How the Seven Countries Study contributed to the definition and development of the Mediterranean diet concept: a 50-year journey. Nutr Metab Cardiovasc Dis. 2015;25(3):245–252.
   PubMed Web of Science ®Google Scholar
• Delarue J. Mediterranean Diet and cardiovascular health: an historical perspective. Br J Nutr. 2021;1–14.
   Web of Science ®Google Scholar
• Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364(9438):937–952.
   PubMed Web of Science ®Google Scholar
• Miller V, Mente A, Dehghan M, et al. Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study. Lancet. 2017;390(10107):2037–2049.
   PubMed Web of Science ®Google Scholar
• Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: executive Summary: a Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2019;74(10):1376–1414.
   PubMed Web of Science ®Google Scholar
• Visseren FLJ, Mach F, Smulders YM, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC). Eur Heart J. 2021;42(34):3227–3337.
   PubMed Web of Science ®Google Scholar
• Ferraro RA, Fischer NM, Xun H, Michos ED. Nutrition and physical activity recommendations from the United States and European cardiovascular guidelines: a comparative review. Curr Opin Cardiol. 2020;35(5):508–516.
   PubMed Web of Science ®Google Scholar
• Belardo D, Michos ED, Blankstein R, et al. Practical, Evidence-Based Approaches to Nutritional Modifications to Reduce Atherosclerotic Cardiovascular Disease: an American Society For Preventive Cardiology Clinical Practice Statement. Am J Prev Cardiol. 2022;10:100323.
   PubMedGoogle Scholar
• Badimon L, Chagas P, Chiva-Blanch G. Diet and Cardiovascular Disease: effects of Foods and Nutrients in Classical and Emerging Cardiovascular Risk Factors. Curr Med Chem. 2019;26(19):3639–3651.
   PubMed Web of Science ®Google Scholar
• Roth GA, Mensah GA, Johnson CO, et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: update From the GBD 2019 Study. J Am Coll Cardiol. 2020;76(25):2982–3021.
   PubMed Web of Science ®Google Scholar
• Divers J, Mayer-Davis EJ, Lawrence JM, et al. Trends in Incidence of Type 1 and Type 2 Diabetes Among Youths — selected Counties and Indian Reservations, United States, 2002–2015. MMWR Morb Mortal Wkly Rep. 2020;69:161–165.
   PubMed Web of Science ®Google Scholar
• International Diabetes Foundation. IDF Diabetes Atlas 10th Edition; 2021. Available from: https://diabetesatlas.org/. Accessed December 8, 2022.
   Google Scholar
• Muntner P, Hardy ST, Fine LJ, et al. Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018. JAMA. 2020;324(12):1190–1200.
   PubMed Web of Science ®Google Scholar
• World Health Organization. Obesity and overweight. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight#:. Accessed March 24, 2022.
   Google Scholar
• Hales CM, Carroll MD, Fryar CD, Ogden CL. Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017-2018. NCHS Data Brief. 2020;3(360):1–8.
   Google Scholar
• Powell-Wiley TM, Poirier P, Burke LE, et al. Obesity and Cardiovascular Disease: a Scientific Statement From the American Heart Association. Circulation. 2021;143(21):e984–e1010.
   PubMed Web of Science ®Google Scholar
• Lloyd-Jones DM, Allen NB, Anderson CAM, et al. Life’s Essential 8: updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: a Presidential Advisory From the American Heart Association. Circulation. 2022;146(5):e18–e43.
   PubMed Web of Science ®Google Scholar
• Benjamin EJ, Muntner P, Alonso A, et al. Heart Disease and Stroke Statistics-2019 Update: a Report From the American Heart Association. Circulation. 2019;139(10):e56–e528.
   PubMed Web of Science ®Google Scholar
• Gantenbein KV, Kanaka-Gantenbein C. Mediterranean Diet as an Antioxidant: the Impact on Metabolic Health and Overall Wellbeing. Nutrients. 2021;13(6):65.
   Web of Science ®Google Scholar
• de la Torre-Moral A, Fabregues S, Bach-Faig A, et al. Family Meals, Conviviality, and the Mediterranean Diet among Families with Adolescents. Int J Environ Res Public Health. 2021;18(5):47.
   Web of Science ®Google Scholar
• Martinez-Gonzalez MA, Salas-Salvado J, Estruch R, et al. Benefits of the Mediterranean Diet: insights From the PREDIMED Study. Prog Cardiovasc Dis. 2015;58(1):50–60.
   PubMed Web of Science ®Google Scholar
• Estruch R, Martinez-Gonzalez MA, Corella D, et al. Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Int Med. 2006;145(1):1–11.
   PubMed Web of Science ®Google Scholar
• Richardson LA, Izuora K, Basu A. Mediterranean Diet and Its Association with Cardiovascular Disease Risk Factors: a Scoping Review. Int J Environ Res Public Health. 2022;19(19):45.
   Web of Science ®Google Scholar
• Ros E, Martinez-Gonzalez MA, Estruch R, et al. Mediterranean diet and cardiovascular health: teachings of the PREDIMED study. Adv Nutr. 2014;5(3):330S–336S.
   PubMed Web of Science ®Google Scholar
• Llorente-Cortes V, Estruch R, Mena MP, et al. Effect of Mediterranean diet on the expression of pro-atherogenic genes in a population at high cardiovascular risk. Atherosclerosis. 2010;208(2):442–450.
   PubMed Web of Science ®Google Scholar
• Keys A, Menotti A, Aravanis C, et al. The seven countries study: 2289 deaths in 15 years. Prev Med. 1984;13(2):141–154.
   PubMed Web of Science ®Google Scholar
• Trichopoulou A, Costacou T, Bamia C, Trichopoulos D. Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med. 2003;348(26):2599–2608.
   PubMed Web of Science ®Google Scholar
• Stewart RA, Wallentin L, Benatar J, et al. Dietary patterns and the risk of major adverse cardiovascular events in a global study of high-risk patients with stable coronary heart disease. Eur Heart J. 2016;37(25):1993–2001.
   PubMed Web of Science ®Google Scholar
• Minhas AS, Hong X, Wang G, et al. Mediterranean-Style Diet and Risk of Preeclampsia by Race in the Boston Birth Cohort. J Am Heart Assoc. 2022;11(9):e022589.
   PubMed Web of Science ®Google Scholar
• de Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation. 1999;99(6):779–785.
   PubMed Web of Science ®Google Scholar
• Kris-Etherton P, Eckel RH, Howard BV, et al. AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-style, National Cholesterol Education Program/American Heart Association Step I Dietary Pattern on Cardiovascular Disease. Circulation. 2001;103(13):1823–1825.
   PubMed Web of Science ®Google Scholar
• Estruch R, Ros E, Salas-Salvado J, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. N Engl J Med. 2018;378(25):e34.
   PubMed Web of Science ®Google Scholar
• Salas-Salvado J, Bullo M, Babio N, et al. Reduction in the incidence of type 2 diabetes with the Mediterranean diet: results of the PREDIMED-Reus nutrition intervention randomized trial. Diabetes Care. 2011;34(1):14–19.
   PubMed Web of Science ®Google Scholar
• Fito M, Estruch R, Salas-Salvado J, et al. Effect of the Mediterranean diet on heart failure biomarkers: a randomized sample from the PREDIMED trial. Eur J Heart Fail. 2014;16(5):543–550.
   PubMed Web of Science ®Google Scholar
• Xia M, Zhong Y, Peng Y, Qian C. Olive oil consumption and risk of cardiovascular disease and all-cause mortality: a meta-analysis of prospective cohort studies. Front Nutr. 2022;9:1041203.
   PubMed Web of Science ®Google Scholar
• Cronin P, Joyce SA, O’Toole PW, O’Connor EM. Dietary Fibre Modulates the Gut Microbiota. Nutrients. 2021;13(5):97.
   Web of Science ®Google Scholar
• Witkowski M, Weeks TL, Hazen SL. Gut Microbiota and Cardiovascular Disease. Circ Res. 2020;127(4):553–570.
   PubMed Web of Science ®Google Scholar
• Koeth RA, Levison BS, Culley MK, et al. gamma-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014;20(5):799–812.
   PubMed Web of Science ®Google Scholar
• Appel LJ, Moore TJ, Obarzanek E, et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med. 1997;336(16):1117–1124.
   PubMed Web of Science ®Google Scholar
• Appel LJ, Brands MW, Daniels SR, et al. Dietary approaches to prevent and treat hypertension: a scientific statement from the American Heart Association. Hypertension. 2006;47(2):296–308.
   PubMed Web of Science ®Google Scholar
• Wickman BE, Enkhmaa B, Ridberg R, et al. Dietary Management of Heart Failure: DASH Diet and Precision Nutrition Perspectives. Nutrients. 2021;13(12):4378.
   PubMed Web of Science ®Google Scholar
• Sacks FM, Svetkey LP, Vollmer WM, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med. 2001;344(1):3–10.
   PubMed Web of Science ®Google Scholar
• Kucharska A, Gajewska D, Kiedrowski M, et al. The impact of individualised nutritional therapy according to DASH diet on blood pressure, body mass, and selected biochemical parameters in overweight/obese patients with primary arterial hypertension: a prospective randomised study. Kardiol Pol. 2018;76(1):158–165.
   PubMed Web of Science ®Google Scholar
• Filippou C, Tatakis F, Polyzos D, et al. Overview of salt restriction in the Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean diet for blood pressure reduction. Rev Cardiovasc Med. 2022;23(1):36.
   PubMed Web of Science ®Google Scholar
• Chiavaroli L, Viguiliouk E, Nishi SK, et al. DASH Dietary Pattern and Cardiometabolic Outcomes: an Umbrella Review of Systematic Reviews and Meta-Analyses. Nutrients. 2019;11(2):209.
   PubMed Web of Science ®Google Scholar
• Campos CL, Wood A, Burke GL, Bahrami H, Bertoni AG. Dietary Approaches to Stop Hypertension Diet Concordance and Incident Heart Failure: the Multi-Ethnic Study of Atherosclerosis. Am J Prev Med. 2019;56(6):819–826.
   PubMed Web of Science ®Google Scholar
• Henzel J, Kepka C, Kruk M, et al. High-Risk Coronary Plaque Regression After Intensive Lifestyle Intervention in Nonobstructive Coronary Disease: a Randomized Study. JACC Cardiovasc Imaging. 2021;14(6):1192–1202.
   PubMed Web of Science ®Google Scholar
• Satija A, Hu FB. Plant-based diets and cardiovascular health. Trends Cardiovasc Med. 2018;28(7):437–441.
   PubMed Web of Science ®Google Scholar
• Satija A, Bhupathiraju SN, Spiegelman D, et al. Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults. J Am Coll Cardiol. 2017;70(4):411–422.
   PubMed Web of Science ®Google Scholar
• Jabri A, Kumar A, Verghese E, et al. Meta-analysis of Effect of Vegetarian Diet on Ischemic Heart Disease and All-cause Mortality. Am J Prev Cardiol. 2021;7:100182.
   PubMedGoogle Scholar
• Gomez-Donoso C, Martinez-Gonzalez MA, Martinez JA, et al. A Provegetarian Food Pattern Emphasizing Preference for Healthy Plant-Derived Foods Reduces the Risk of Overweight/Obesity in the SUN Cohort. Nutrients. 2019;11(7):97.
   PubMed Web of Science ®Google Scholar
• Orlich MJ, Singh PN, Sabate J, et al. Vegetarian dietary patterns and mortality in Adventist Health Study 2. JAMA Intern Med. 2013;173(13):1230–1238.
   PubMed Web of Science ®Google Scholar
• Matsumoto S, Beeson WL, Shavlik DJ, et al. Association between vegetarian diets and cardiovascular risk factors in non-Hispanic white participants of the Adventist Health Study-2. J Nutr Sci. 2019;8:e6.
   PubMed Web of Science ®Google Scholar
• Smith CE, Tucker KL. Health benefits of cereal fibre: a review of clinical trials. Nutr Res Rev. 2011;24(1):118–131.
   PubMed Web of Science ®Google Scholar
• Howarth NC, Saltzman E, Roberts SB. Dietary fiber and weight regulation. Nutr Rev. 2001;59(5):129–139.
   PubMed Web of Science ®Google Scholar
• Najjar RS, Feresin RG. Plant-Based Diets in the Reduction of Body Fat: physiological Effects and Biochemical Insights. Nutrients. 2019;11(11):64.
   Web of Science ®Google Scholar
• Martinez-Gonzalez MA, Sanchez-Tainta A, Corella D, et al. A provegetarian food pattern and reduction in total mortality in the Prevencion con Dieta Mediterranea (PREDIMED) study. Am J Clin Nutr. 2014;100 Suppl 1:320S–328S.
   PubMed Web of Science ®Google Scholar
• Choi Y, Larson N, Steffen LM, et al. Plant-Centered Diet and Risk of Incident Cardiovascular Disease During Young to Middle Adulthood. J Am Heart Assoc. 2021;10(16):e020718.
   PubMed Web of Science ®Google Scholar
• Yokoyama Y, Nishimura K, Barnard ND, et al. Vegetarian diets and blood pressure: a meta-analysis. JAMA Intern Med. 2014;174(4):577–587.
   PubMed Web of Science ®Google Scholar
• Shah B, Newman JD, Woolf K, et al. Anti-Inflammatory Effects of a Vegan Diet Versus the American Heart Association-Recommended Diet in Coronary Artery Disease Trial. J Am Heart Assoc. 2018;7(23):e011367.
   PubMed Web of Science ®Google Scholar
• Rizzo NS, Sabate J, Jaceldo-Siegl K, Fraser GE. Vegetarian dietary patterns are associated with a lower risk of metabolic syndrome: the adventist health study 2. Diabetes Care. 2011;34(5):1225–1227.
   PubMed Web of Science ®Google Scholar
• Craig WJ, Mangels AR, Fresan U, et al. The Safe and Effective Use of Plant-Based Diets with Guidelines for Health Professionals. Nutrients. 2021;13(11):453.
   PubMed Web of Science ®Google Scholar
• Wang DD, Li Y, Bhupathiraju SN, et al. Fruit and Vegetable Intake and Mortality: results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies. Circulation. 2021;143(17):1642–1654.
   PubMed Web of Science ®Google Scholar
• Aune D, Keum N, Giovannucci E, et al. Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies. BMJ. 2016;353:i2716.
   PubMed Web of Science ®Google Scholar
• Aune D, Keum N, Giovannucci E, et al. Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies. BMC Med. 2016;14(1):207.
   PubMed Web of Science ®Google Scholar
• Juul F, Deierlein AL, Vaidean G, Quatromoni PA, Parekh N. Ultra-processed Foods and Cardiometabolic Health Outcomes: from Evidence to Practice. Curr Atheroscler Rep. 2022;24(11):849–860.
   PubMed Web of Science ®Google Scholar
• Monteiro CA, Cannon G, Moubarac JC, Levy RB, Louzada MLC, Jaime PC. The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing. Public Health Nutr. 2018;21(1):5–17.
   PubMed Web of Science ®Google Scholar
• Juul F, Vaidean G, Lin Y, Deierlein AL, Parekh N. Ultra-Processed Foods and Incident Cardiovascular Disease in the Framingham Offspring Study. J Am Coll Cardiol. 2021;77(12):1520–1531.
   PubMed Web of Science ®Google Scholar
• Rico-Campa A, Martinez-Gonzalez MA, Alvarez-Alvarez I, et al. Association between consumption of ultra-processed foods and all cause mortality: SUN prospective cohort study. BMJ. 2019;365:l1949.
   PubMedGoogle Scholar
• Hall KD, Ayuketah A, Brychta R, et al. Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: an Inpatient Randomized Controlled Trial of Ad Libitum Food Intake. Cell Metab. 2019;30(1):67–77 e63.
   PubMed Web of Science ®Google Scholar
• Kirkpatrick CF, Bolick JP, Kris-Etherton PM, et al. Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: a scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force. J Clin Lipidol. 2019;13(5):689–711 e681.
   PubMed Web of Science ®Google Scholar
• Kirkpatrick CF, Willard KE, Maki KC. Keto is Trending: implications for Body Weight and Lipid Management. Curr Cardiol Rep. 2022;24(9):1093–1100.
   PubMed Web of Science ®Google Scholar
• O’Neill B, Raggi P. The ketogenic diet: pros and cons. Atherosclerosis. 2020;292:119–126.
   PubMed Web of Science ®Google Scholar
• D’Andrea Meira I, Romao TT. Ketogenic Diet and Epilepsy: what We Know So Far. Front Neurosci. 2019;13:5.
   PubMed Web of Science ®Google Scholar
• Pinto A, Bonucci A, Maggi E, Corsi M, Businaro R. Anti-Oxidant and Anti-Inflammatory Activity of Ketogenic Diet: new Perspectives for Neuroprotection in Alzheimer’s Disease. Antioxidants. 2018;7(5):w365.
   Web of Science ®Google Scholar
• Hallberg SJ, McKenzie AL, Williams PT, et al. Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: an Open-Label, Non-Randomized, Controlled Study. Diabetes Ther. 2018;9(2):583–612.
   PubMed Web of Science ®Google Scholar
• Tinguely D, Gross J, Kosinski C. Efficacy of Ketogenic Diets on Type 2 Diabetes: a Systematic Review. Curr Diab Rep. 2021;21(9):32.
   PubMed Web of Science ®Google Scholar
• Choi YJ, Jeon SM, Shin S. Impact of a Ketogenic Diet on Metabolic Parameters in Patients with Obesity or Overweight and with or without Type 2 Diabetes: a Meta-Analysis of Randomized Controlled Trials. Nutrients. 2020;12(7):r45.
   Web of Science ®Google Scholar
• Bueno NB, de Melo IS, de Oliveira SL. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials. Br J Nutr. 2013;110(7):1178–1187.
   PubMed Web of Science ®Google Scholar
• Mansoor N, Vinknes KJ, Veierod MB, Retterstol K. Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials. Br J Nutr. 2016;115(3):466–479.
   PubMed Web of Science ®Google Scholar
• Sackner-Bernstein J, Kanter D, Kaul S. Dietary Intervention for Overweight and Obese Adults: comparison of Low-Carbohydrate and Low-Fat Diets. A Meta-Analysis. PLoS One. 2015;10(10):e0139817.
   PubMed Web of Science ®Google Scholar
• Johnstone AM, Horgan GW, Murison SD, Bremner DM, Lobley GE. Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum. Am J Clin Nutr. 2008;87(1):44–55.
   PubMed Web of Science ®Google Scholar
• Buren J, Ericsson M, Damasceno NRT, Sjodin A, Ketogenic Low-Carbohydrate A. High-Fat Diet Increases LDL Cholesterol in Healthy, Young, Normal-Weight Women: a Randomized Controlled Feeding Trial. Nutrients. 2021;13(3):45645.
   Web of Science ®Google Scholar
• Retterstol K, Svendsen M, Narverud I, Holven KB. Effect of low carbohydrate high fat diet on LDL cholesterol and gene expression in normal-weight, young adults: a randomized controlled study. Atherosclerosis. 2018;279:52–61.
   PubMed Web of Science ®Google Scholar
• Goldberg IJ, Ibrahim N, Bredefeld C, et al. Ketogenic diets, not for everyone. J Clin Lipidol. 2021;15(1):61–67.
   PubMed Web of Science ®Google Scholar
• Joo M, Moon S, Lee YS, Kim MG. Effects of very low-carbohydrate ketogenic diets on lipid profiles in normal-weight (body mass index < 25 kg/m2) adults: a meta-analysis. Nutr Rev. 2023;nuad017. doi:10.1093/nutrit/nuad017
   PubMed Web of Science ®Google Scholar
• Dong TA, Sandesara PB, Dhindsa DS, et al. Intermittent Fasting: a Heart Healthy Dietary Pattern? Am J Med. 2020;133(8):901–907.
   PubMed Web of Science ®Google Scholar
• Tinsley GM, Horne BD. Intermittent fasting and cardiovascular disease: current evidence and unresolved questions. Future Cardiol. 2018;14(1):47–54.
   PubMed Web of Science ®Google Scholar
• Crupi AN, Haase J, Brandhorst S, Longo VD. Periodic and Intermittent Fasting in Diabetes and Cardiovascular Disease. Curr Diab Rep. 2020;20(12):83.
   PubMed Web of Science ®Google Scholar
• Varady KA, Cienfuegos S, Ezpeleta M, Gabel K. Cardiometabolic Benefits of Intermittent Fasting. Annu Rev Nutr. 2021;41:333–361.
   PubMed Web of Science ®Google Scholar
• Allaf M, Elghazaly H, Mohamed OG, et al. Intermittent fasting for the prevention of cardiovascular disease. Cochrane Database Syst Rev. 2021;1(1):CD013496.
   PubMedGoogle Scholar
• Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Res Rev. 2017;39:46–58.
   PubMed Web of Science ®Google Scholar
• Wegman MP, Guo MH, Bennion DM, et al. Practicality of intermittent fasting in humans and its effect on oxidative stress and genes related to aging and metabolism. Rejuvenation Res. 2015;18(2):162–172.
   PubMed Web of Science ®Google Scholar
• Park J, Seo YG, Paek YJ, Song HJ, Park KH, Noh HM. Effect of alternate-day fasting on obesity and cardiometabolic risk: a systematic review and meta-analysis. Metabolism. 2020;111:154336.
   PubMed Web of Science ®Google Scholar
• Trepanowski JF, Kroeger CM, Barnosky A, et al. Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: a Randomized Clinical Trial. JAMA Intern Med. 2017;177(7):930–938.
   PubMed Web of Science ®Google Scholar
• Liu D, Huang Y, Huang C, et al. Calorie Restriction with or without Time-Restricted Eating in Weight Loss. N Engl J Med. 2022;386(16):1495–1504.
   PubMed Web of Science ®Google Scholar
• Moro T, Tinsley G, Bianco A, et al. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. J Transl Med. 2016;14(1):290.
   PubMedGoogle Scholar
• Schroder JD, Falqueto H, Manica A, et al. Effects of time-restricted feeding in weight loss, metabolic syndrome and cardiovascular risk in obese women. J Transl Med. 2021;19(1):3.
   PubMed Web of Science ®Google Scholar
• Wilkinson MJ, Manoogian ENC, Zadourian A, et al. Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome. Cell Metab. 2020;31(1):92–104 e105.
   PubMed Web of Science ®Google Scholar
• Manoogian ENC, Zadourian A, Lo HC, et al. Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: the Healthy Heroes randomized control trial. Cell Metab. 2022;34(10):1442–1456 e1447.
   PubMed Web of Science ®Google Scholar
• Longo VD, Panda S. Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan. Cell Metab. 2016;23(6):1048–1059.
   PubMed Web of Science ®Google Scholar
• de Goede P, Foppen E, Ritsema W, Korpel NL, Yi CX, Kalsbeek A. Time-Restricted Feeding Improves Glucose Tolerance in Rats, but Only When in Line With the Circadian Timing System. Front Endocrinol. 2019;10:554.
   PubMed Web of Science ®Google Scholar
• Sanchez-Rodriguez E, Egea-Zorrilla A, Plaza-Diaz J, et al. The Gut Microbiota and Its Implication in the Development of Atherosclerosis and Related Cardiovascular Diseases. Nutrients. 2020;12(3):605.
   PubMed Web of Science ®Google Scholar
• Smits LP, Kootte RS, Levin E, et al. Effect of Vegan Fecal Microbiota Transplantation on Carnitine- and Choline-Derived Trimethylamine-N-Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome. J Am Heart Assoc. 2018;7(7):e008342.
   PubMed Web of Science ®Google Scholar
• Reynolds A, Mann J, Cummings J, Winter N, Mete E, Te Morenga L. Carbohydrate quality and human health: a series of systematic reviews and meta-analyses. Lancet. 2019;393(10170):434–445.
   PubMed Web of Science ®Google Scholar
• Guo Y, Li X, Wang Z, Yu B. Gut Microbiota Dysbiosis in Human Hypertension: a Systematic Review of Observational Studies. Front Cardiovasc Med. 2021;8:650227.
   PubMed Web of Science ®Google Scholar
• Richards EM, Li J, Stevens BR, Pepine CJ, Raizada MK, Microbiome G. Neuroinflammation in Hypertension. Circ Res. 2022;130(3):401–417.
   PubMed Web of Science ®Google Scholar
• Nakai M, Ribeiro RV, Stevens BR, et al. Essential Hypertension Is Associated With Changes in Gut Microbial Metabolic Pathways: a Multisite Analysis of Ambulatory Blood Pressure. Hypertension. 2021;78(3):804–815.
   PubMed Web of Science ®Google Scholar
• Lee Y, Nemet I, Wang Z, et al. Longitudinal Plasma Measures of Trimethylamine N-Oxide and Risk of Atherosclerotic Cardiovascular Disease Events in Community-Based Older Adults. J Am Heart Assoc. 2021;10(17):e020646.
   PubMed Web of Science ®Google Scholar
• Duttaroy AK. Role of Gut Microbiota and Their Metabolites on Atherosclerosis, Hypertension and Human Blood Platelet Function: a Review. Nutrients. 2021;13(1):144.
   PubMed Web of Science ®Google Scholar
• Lichtenstein AH, Appel LJ, Vadiveloo M, et al. 2021 Dietary Guidance to Improve Cardiovascular Health: a Scientific Statement From the American Heart Association. Circulation. 2021;144(23):e472–e487.
   PubMed Web of Science ®Google Scholar
• Minich DM. A Review of the Science of Colorful, Plant-Based Food and Practical Strategies for “Eating the Rainbow”. J Nutr Metab. 2019;2019:2125070.
   PubMed Web of Science ®Google Scholar
• Kwok CS, Gulati M, Michos ED, et al. Dietary components and risk of cardiovascular disease and all-cause mortality: a review of evidence from meta-analyses. Eur J Prev Cardiol. 2019;26(13):1415–1429.
   PubMed Web of Science ®Google Scholar
• Jiang L, Wang J, Xiong K, Xu L, Zhang B, Ma A. Intake of Fish and Marine n-3 Polyunsaturated Fatty Acids and Risk of Cardiovascular Disease Mortality: a Meta-Analysis of Prospective Cohort Studies. Nutrients. 2021;13:7.
   Web of Science ®Google Scholar
• Bhupathi V, Mazariegos M, Cruz Rodriguez JB, Deoker A. Dairy Intake and Risk of Cardiovascular Disease. Curr Cardiol Rep. 2020;22(3):11.
   PubMed Web of Science ®Google Scholar
• Papier K, Knuppel A, Syam N, Jebb SA, Key TJ. Meat consumption and risk of ischemic heart disease: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2021;1–12.
   Web of Science ®Google Scholar
• Orlich MJ, Sabate J, Mashchak A, et al. Ultra-processed food intake and animal-based food intake and mortality in the Adventist Health Study-2. Am J Clin Nutr. 2022;115(6):1589–1601.
   PubMed Web of Science ®Google Scholar
• Zhong VW, Van Horn L, Greenland P, et al. Associations of Processed Meat, Unprocessed Red Meat, Poultry, or Fish Intake With Incident Cardiovascular Disease and All-Cause Mortality. JAMA Intern Med. 2020;180(4):503–512.
   PubMed Web of Science ®Google Scholar
• Wang M, Wang Z, Lee Y, et al. Dietary Meat, Trimethylamine N-Oxide-Related Metabolites, and Incident Cardiovascular Disease Among Older Adults: the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2022;42(9):e273–e288.
   PubMed Web of Science ®Google Scholar
• Koeth RA, Wang Z, Levison BS, et al. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med. 2013;19(5):576–585.
   PubMed Web of Science ®Google Scholar
• Sacks FM, Katan M. Randomized clinical trials on the effects of dietary fat and carbohydrate on plasma lipoproteins and cardiovascular disease. Am J Med. 2002;113:13S–24S.
   PubMed Web of Science ®Google Scholar
• Khaw KT, Sharp SJ, Finikarides L, et al. Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women. BMJ Open. 2018;8(3):e020167.
   PubMed Web of Science ®Google Scholar
• Neelakantan N, Seah JYH, van Dam RM. The Effect of Coconut Oil Consumption on Cardiovascular Risk Factors: a Systematic Review and Meta-Analysis of Clinical Trials. Circulation. 2020;141(10):803–814.
   PubMed Web of Science ®Google Scholar
• Innes JK, Calder PC. Omega-6 fatty acids and inflammation. Prostaglandins Leukot Essent Fatty Acids. 2018;132:41–48.
   PubMed Web of Science ®Google Scholar
• Marklund M, Wu JHY, Imamura F, et al. Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality. Circulation. 2019;139(21):2422–2436.
   PubMed Web of Science ®Google Scholar
• Sanders TAB. Omega-6 Fatty Acids and Cardiovascular Disease. Circulation. 2019;139(21):2437–2439.
   PubMed Web of Science ®Google Scholar
• Naghshi S, Aune D, Beyene J, Mobarak S, Asadi M, Sadeghi O. Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies. BMJ. 2021;375:n2213.
   PubMedGoogle Scholar
• Zhou Y, Wang T, Zhai S, Li W, Meng Q. Linoleic acid and breast cancer risk: a meta-analysis. Public Health Nutr. 2016;19(8):1457–1463.
   PubMed Web of Science ®Google Scholar
• Lu X, Yu H, Ma Q, Shen S, Das UN. Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction. Lipids Health Dis. 2010;9:106.
   PubMed Web of Science ®Google Scholar
• Zock PL, Katan MB. Linoleic acid intake and cancer risk: a review and meta-analysis. Am J Clin Nutr. 1998;68(1):142–153.
   PubMed Web of Science ®Google Scholar
• Rippe JM, Angelopoulos TJ. Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: current Understanding. Nutrients. 2016;8(11):526.
   PubMed Web of Science ®Google Scholar
• Yang Q, Zhang Z, Gregg EW, Flanders WD, Merritt R, Hu FB. Added sugar intake and cardiovascular diseases mortality among US adults. JAMA Intern Med. 2014;174(4):516–524.
   PubMed Web of Science ®Google Scholar
• Hoek AG, Oort S, Mukamal KJ, Beulens JWJ. Alcohol Consumption and Cardiovascular Disease Risk: placing New Data in Context. Curr Atheroscler Rep. 2022;24(1):51–59.
   PubMed Web of Science ®Google Scholar
• Marcus GM, Vittinghoff E, Whitman IR, et al. Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events. An Intern Med. 2021;174(11):1503–1509.
   PubMed Web of Science ®Google Scholar
• Hashimi H, Boggs K, Harada CN. Cooking demonstrations to teach nutrition counseling and social determinants of health. Educ Health. 2020;33(2):74–78.
   PubMed Web of Science ®Google Scholar
• Spahn JM, Reeves RS, Keim KS, et al. State of the evidence regarding behavior change theories and strategies in nutrition counseling to facilitate health and food behavior change. J Am Diet Assoc. 2010;110(6):879–891.
   PubMedGoogle Scholar
• Aggarwal M, Grady A, Desai D, et al. Successful Implementation of Healthful Nutrition Initiatives into Hospitals. Am J Med. 2020;133(1):19–25.
   PubMed Web of Science ®Google Scholar
• Matsuzaki K, Fukushima N, Saito Y, et al. The Effects of Long-Term Nutrition Counseling According to the Behavioral Modification Stages in Patients with Cardiovascular Disease. Nutrients. 2021;13(2):e4.
   Web of Science ®Google Scholar
• LeBlanc-Morales N. Culinary Medicine: patient Education for Therapeutic Lifestyle Changes. Crit Care Nurs Clin North Am. 2019;31(1):109–123.
   PubMed Web of Science ®Google Scholar
• Donohue JA, Severson T, Martin LP. The food pharmacy: theory, implementation, and opportunities. Am J Prev Cardiol. 2021;5:100145.
   PubMedGoogle Scholar
• Metcalfe JJ, McCaffrey J, Schumacher M, Kownacki C, Prescott MP. Community-based nutrition education and hands-on cooking intervention increases farmers’ market use and vegetable servings. Public Health Nutr. 2022;25(9):2601–2613.
   PubMed Web of Science ®Google Scholar
• O’Connor M. DOCTOR’S ORDERS ‘Shop With Your Doc’ program improves food choices. Hosp Health Netw. 2017;91(2):13.
   Google Scholar
• Petersen MR, Freeman AM, Madrid M, Aggarwal M. Strategies for Incorporating Lifestyle Medicine in Everyday Hospital Practice. Am J Lifestyle Med. 2021;15(5):531–537.
   PubMed Web of Science ®Google Scholar
• Steca P, Monzani D, Greco A, et al. Stability and change of lifestyle profiles in cardiovascular patients after their first acute coronary event. PLoS One. 2017;12(8):e0183905.
   PubMed Web of Science ®Google Scholar
• Moran A, Krepp EM, Johnson Curtis C, Lederer A. An Intervention to Increase Availability of Healthy Foods and Beverages in New York City Hospitals: the Healthy Hospital Food Initiative, 2010-2014. Prev Chronic Dis. 2016;13:E77.
   PubMed Web of Science ®Google Scholar
• Fischer NM, Duffy EY, Michos ED. Protecting Our Youth: support Policy to Combat Health Disparities Fueled by Targeted Food Advertising. J Am Heart Assoc. 2021;10(1):e018900.
   PubMed Web of Science ®Google Scholar
• Ramesh G, Belardo D, Gulati M, Ostfeld RJ, Michos ED. Agricultural policy and societal factors influence patients’ ability to follow a healthy diet. Am J Prev Cardiol. 2021;8:100285.
   PubMedGoogle Scholar
• Cooksey-Stowers K, Schwartz MB, Brownell KD. Food Swamps Predict Obesity Rates Better Than Food Deserts in the United States. Int J Environ Res Public Health. 2017;14(11):34.
   Web of Science ®Google Scholar
• Mannoh I, Hussien M, Commodore-Mensah Y, Michos ED. Impact of social determinants of health on cardiovascular disease prevention. Curr Opin Cardiol. 2021;36(5):572–579.
   PubMed Web of Science ®Google Scholar
• Caceres BA, Bynon M, Doan D, Makarem N, McClain AC, VanKim N. Diet, Food Insecurity, and CVD Risk in Sexual and Gender Minority Adults. Current Atheroscler Rep. 2022;24(1):41–50.
   PubMed Web of Science ®Google Scholar
• Shahu A, Okunrintemi V, Tibuakuu M, et al. Income disparity and utilization of cardiovascular preventive care services among U.S. adults. Am J Prev Cardiol. 2021;8:100286.
   PubMedGoogle Scholar
• Decker D, Flynn M. Food Insecurity and Chronic Disease: addressing Food Access as a Healthcare Issue. R I Med J. 2018;101(4):28–30.
   Google Scholar
• Dhurandhar EJ. The food-insecurity obesity paradox: a resource scarcity hypothesis. Physiol Behav. 2016;162:88–92.
   PubMed Web of Science ®Google Scholar
• Liu Y, Eicher-Miller HA. Food Insecurity and Cardiovascular Disease Risk. Curr Atheroscler Rep. 2021;23(6):24.
   PubMed Web of Science ®Google Scholar
• Allicock M, Johnson LS, Leone L, et al. Promoting fruit and vegetable consumption among members of black churches, Michigan and North Carolina, 2008-2010. Prev Chronic Dis. 2013;10:E33.
   PubMed Web of Science ®Google Scholar
• Vedanthan R, Bansilal S, Soto AV, et al. Family-Based Approaches to Cardiovascular Health Promotion. J Am Coll Cardiol. 2016;67(14):1725–1737.
   PubMed Web of Science ®Google Scholar
• Van Horn L, Lenders CM, Pratt CA, et al. Advancing Nutrition Education, Training, and Research for Medical Students, Residents, Fellows, Attending Physicians, and Other Clinicians: building Competencies and Interdisciplinary Coordination. Adv Nutr. 2019;10(6):1181–1200.
   PubMed Web of Science ®Google Scholar