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ORIGINAL RESEARCH

Clinical Characteristics, Patterns of Use, and incidence of Adverse Events in Patients With Nonvalvular Atrial Fibrillation Treated With Oral Anticoagulants in Colombia

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Pages 157-167 | Received 08 Oct 2022, Accepted 27 Feb 2023, Published online: 27 Mar 2023

References

  • Molteni M, Polo Friz H, Primitz L, et al. The definition of valvular and non-valvular atrial fibrillation: results of a physicians’ survey. Europace. 2014;16(12):1720–1725.
  • Lip GY, Nieuwlaat R, Pisters R, et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest. 2010;137(2):263–272. doi:10.1378/chest.09-1584
  • Olesen JB, Lip GY, Lindhardsen J, et al. Risks of thromboembolism and bleeding with thromboprophylaxis in patients with atrial fibrillation: a net clinical benefit analysis using a ‘real world’ nationwide cohort study. Thromb Haemost. 2011;106(4):739–749. doi:10.1160/TH11-05-0364
  • Banerjee A, Lane DA, Torp-Pedersen C, et al. Net clinical benefit of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) versus no treatment in a ‘real world’ atrial fibrillation population: a modelling analysis based on a nationwide cohort study. Thromb Haemost. 2012;107(3):584–589. doi:10.1160/TH11-11-0784
  • Lip GYH, Keshishian A, Kang A, et al. Effectiveness and safety of oral anticoagulants among non-valvular atrial fibrillation patients with polypharmacy. Eur Heart J Cardiovasc Pharmacother. 2021;7(5):405–414. doi:10.1093/ehjcvp/pvaa117
  • Pinto DA, Sánchez-Vallejo CA, Pedraza AL, et al. Description of patients with non-valvular atrial fibrillation admitted to the emergency room. Rev Colomb Cardiol. 2016;23(4):270–276.
  • Archontakis-Barakakis P, Li W, Kalaitzoglou D, et al. Effectiveness and safety of intracranial events associated with the use of direct oral anticoagulants for atrial fibrillation: a systematic review and meta-analysis of 92 studies. Br J Clin Pharmacol. 2022;88(11):4663–4675. doi:10.1111/bcp.15464
  • Machado-Alba JE, Gaviria-Mendoza A, Machado-Duque ME, et al. Use of non-vitamin K antagonist oral anticoagulants in Colombia: a descriptive study using a national administrative healthcare database. Pharmacoepidemiol Drug Saf. 2021;30(4):426–434. doi:10.1002/pds.5124
  • Nguyen TN, Hilmer SN, Cumming RG. Review of epidemiology and management of atrial fibrillation in developing countries. Int J Cardiol. 2013;167(6):2412–2420. doi:10.1016/j.ijcard.2013.01.184
  • Rosselli D, Rodríguez AJ, García ÁA, et al. Atrial fibrillation prevalence in a Colombian university hospital. Rev Colom Cardiol. 2013;20(6):383–385.
  • Franco JS, Vizcaya D. Availability of secondary healthcare data for conducting pharmacoepidemiology studies in Colombia: a systematic review. Pharmacol Res Perspect. 2020;8(5):e00661. doi:10.1002/prp2.661
  • Medina-Morales DA, Machado-Duque ME, Gaviria-Mendoza A, et al. Clinical characteristics and stratification of the cerebrovascular accident risk among patients with atrial fibrillation in Colombia, 2011–2016. Expert Rev Cardiovasc Ther. 2021;19(2):181–187. doi:10.1080/14779072.2021.1873766
  • Sakuma I, Uchiyama S, Atarashi H, et al. Clinical risk factors of stroke and major bleeding in patients with non-valvular atrial fibrillation under rivaroxaban: the EXPAND Study sub-analysis. Heart Vessels. 2019;34(11):1839–1851. doi:10.1007/s00380-019-01425-x
  • Brown JD, Shewale AR, Dherange P, et al. A comparison of oral anticoagulant use for atrial fibrillation in the pre- and post-DOAC Eras. Drugs Aging. 2016;33(6):427–436. doi:10.1007/s40266-016-0369-y
  • Bodega F, Russi A, Melillo F, et al. INSigHT (Italian DOACs San Raffaele Hospital) registry investigators. Direct oral anticoagulants in patients with nonvalvular atrial fibrillation and extreme body weight. Eur J Clin Invest. 2022;52(1):e13658. doi:10.1111/eci.13658
  • Gedikli Ö, Altay S, Ünlü S, et al. Real-life data of major and minor bleeding events with direct oral anticoagulants in the one-year follow-up period: the NOAC-Turk study. Anatol J Cardiol. 2021;25(3):196–204. doi:10.5152/AnatolJCardiol.2021.57635
  • Almas T, Musheer A, Ejaz A, et al. Efficacy and safety of direct oral anticoagulants with and without Aspirin: a systematic review and Meta-analysis. Int J Cardiol Heart Vasc. 2022;40:101016. doi:10.1016/j.ijcha.2022.101016
  • van den Ham HA, Souverein PC, Klungel OH, et al. Major bleeding in users of direct oral anticoagulants in atrial fibrillation: a pooled analysis of results from multiple population-based cohort studies. Pharmacoepidemiol Drug Saf. 2021;30(10):1339–1352. doi:10.1002/pds.5317
  • Lobraico-Fernandez J, Baksh S, Nemec E. Elderly bleeding risk of direct oral anticoagulants in nonvalvular atrial fibrillation: a systematic review and meta-analysis of cohort studies. Drugs R D. 2019;19(3):235–245. doi:10.1007/s40268-019-0275-y
  • Giner-Soriano M, Cortes J, Gomez-Lumbreras A, et al. The use and adherence of oral anticoagulants in primary health care in catalunya, Spain: a real-world data cohort study. Aten Primaria. 2020;52(8):529–538. doi:10.1016/j.aprim.2020.05.016
  • Hindricks G, Potpara T, Dagres N, et al.; ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European association for cardio-thoracic surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special contribution of the European heart rhythm association (EHRA) of the ESC. Eur Heart J. 2021;42(5):373–498. doi:10.1093/eurheartj/ehaa612
  • Rogula S, Gąsecka A, Mazurek T, et al. Safety and efficacy of DOACs in patients with advanced and end-stage renal disease. Int J Environ Res Public Health. 2022;19(3):1436. doi:10.3390/ijerph19031436
  • Ellinghaus P, Perzborn E, Hauenschild P, et al. Expression of pro-inflammatory genes in human endothelial cells: comparison of rivaroxaban and dabigatran. Thromb Res. 2016;142:44–51. doi:10.1016/j.thromres.2016.04.008
  • Ishibashi Y, Matsui T, Yamagishi S. Apixaban exerts anti-inflammatory effects in mesangial cells by blocking thrombin/protease-activated receptor-1 system. Thromb Res. 2014;134(6):1365–1367. doi:10.1016/j.thromres.2014.09.028
  • Machado-Alba JE, Machado-Duque ME, Gaviria-Mendoza A. Extreme polypharmacy: the need to mint a new term. Pharmacoepidemiol Drug Saf. 2020;29(2):224–225. doi:10.1002/pds.4942
  • Castro-Rodríguez A, Machado-Duque ME, Gaviria-Mendoza A, et al. Factors related to excessive polypharmacy (≥15 medications) in an outpatient population from Colombia. Int J Clin Pract;2018. e13278. doi:10.1111/ijcp.13278
  • Machado-Duque ME, Castaño-Montoya JP, Medina-Morales DA, et al. Drugs with anticholinergic potential and risk of falls with hip fracture in the elderly patients: a case-control study. J Geriatr Psychiatry Neurol. 2018;31(2):63–69. doi:10.1177/0891988718757370
  • Machado-Duque ME, Castaño-Montoya JP, Medina-Morales DA, et al. Association between the use of benzodiazepines and opioids with the risk of falls and Hip fractures in older adults. Int Psychogeriatr. 2018;30(7):941–946. doi:10.1017/S1041610217002745
  • Lip GY, Clementy N, Pericart L, et al. Stroke and major bleeding risk in elderly patients aged ≥75 years with atrial fibrillation: the Loire Valley atrial fibrillation project. Stroke. 2015;46(1):143–150. doi:10.1161/STROKEAHA.114.007199
  • Steinberg BA, Kim S, Thomas L, et al. Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigators and Patients. Lack of concordance between empirical scores and physician assessments of stroke and bleeding risk in atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation (ORBIT-AF) registry. Circulation. 2014;129(20):2005–2012. doi:10.1161/CIRCULATIONAHA.114.008643
  • Sanghai SR, Liu W, Wang W, et al. Prevalence of frailty and associations with oral anticoagulant prescribing in atrial fibrillation. J Gen Intern Med. 2022;37(4):730–736. doi:10.1007/s11606-021-06834-1
  • Sasaki S, Sotomi Y, Hirata A, et al. Comparison of low-dose direct oral anticoagulants for patients <80 Versus ≥80 years of age with atrial fibrillation. Am J Cardiol. 2022;162:86–91. doi:10.1016/j.amjcard.2021.09.019
  • Zhang XL, Zhang XW, Wang TY, et al. Off-label under- and overdosing of direct oral anticoagulants in patients with atrial fibrillation: a meta-analysis. Circ Cardiovasc Qual Outcomes. 2021;14(12):e007971. doi:10.1161/CIRCOUTCOMES.121.007971
  • Toorop MMA, Chen Q, Tichelaar VYIG, et al. Predictors, time course, and outcomes of persistence patterns in oral anticoagulation for non-valvular atrial fibrillation: a Dutch nationwide cohort study. Eur Heart J. 2021;42(40):4126–4137. doi:10.1093/eurheartj/ehab421
  • Banerjee A, Benedetto V, Gichuru P, et al. Adherence and persistence to direct oral anticoagulants in atrial fibrillation: a population-based study. Heart. 2020;106(2):119–126. doi:10.1136/heartjnl-2019-315307
  • Hadžibegović I, Jurin I, Letilović T, et al. Changes of recommended anticoagulation therapy in patients with atrial fibrillation and high thrombotic risk: long-term follow-up data from two hospital centers. Expert Rev Cardiovasc Ther. 2021;19(9):857–863. doi:10.1080/14779072.2021.1962293
  • Kirchmayer U, Narduzzi S, Mayer F, et al. Safety and effectiveness of direct oral anticoagulants versus vitamin K antagonists: results from 3 Italian regions. Recenti Prog Med. 2019;110(4):195–202. doi:10.1701/3154.31345
  • ROCKET AF Study Investigators. Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation: rationale and design of the ROCKET AF study. Am Heart J. 2010;159(3):340–347.e1. doi:10.1016/j.ahj.2009.11.025
  • Bahit MC, Lopes RD, Wojdyla DM, et al. Apixaban in patients with atrial fibrillation and prior coronary artery disease: insights from the ARISTOTLE trial. Int J Cardiol. 2013;170(2):215–220. doi:10.1016/j.ijcard.2013.10.062
  • Carnicelli AP, Hong H, Connolly SJ, et al. COMBINE AF (A collaboration between multiple institutions to better investigate non-vitamin K antagonist oral anticoagulant use in atrial fibrillation) investigators. Direct oral anticoagulants versus warfarin in patients with atrial fibrillation: patient-level network meta-analyses of randomized clinical trials with interaction testing by age and sex. Circulation. 2022;145(4):242–255. doi:10.1161/CIRCULATIONAHA.121.056355