References
- Breast cancer statistics [webpage on the internet]LondonCancer Research UK [updated November 27, 2014 Available from: http://www.cancerresearchuk.org/cancer-info/cancerstats/types/breast/Accessed January 15, 2015
- YuDHungMCOverexpression of ErbB2 in cancer and ErbB2-targeting strategiesOncogene2000196115612111156524
- SlamonDJLeyland-JonesBShakSUse of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2N Engl J Med200134478379211248153
- Piccart-GebhartMJProcterMLeyland-JonesBHerceptin Adjuvant (HERA) Trial Study TeamTrastuzumab after adjuvant chemotherapy in HER2-positive breast cancerN Engl J Med20053531659167216236737
- MolinaMACodony-ServatJAlbanellJRojoFArribasJBaselgaJTrastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cellsCancer Res2001614744474911406546
- ZeglinskiMLudkeAJassalDSSingalPKTrastuzumab-induced cardiac dysfunction: a ‘dual-hit’Exp Clin Cardiol201116707422065936
- FloydJDNguyenDTLobinsRLBashirQDollDCPerryMCCardiotoxicity of cancer therapyJ Clin Oncol2005237685769616234530
- WadhwaDFallah-RadNGrenierDTrastuzumab mediated cardiotoxicity in the setting of adjuvant chemotherapy for breast cancer: a retrospective studyBreast Cancer Res Treat200911735736419082707
- GunaldiMDumanBBAfsarCURisk factors for developing cardiotoxicity of trastuzumab in breast cancer patients: an observational single-centre studyJ Oncol Pharm Pract Epub 172015
- SatarianoWARaglandDRThe effect of comorbidity on 3-year survival of women with primary breast cancerAnn Intern Med19941201041108256968
- ChoHSMasonKRamyarKXStructure of the extracellular region of HER2 alone and in complex with the Herceptin FabNature200342175676012610629
- SeshadriRFirgairaFAHorsfallDJMcCaulKSetlurVKitchenPClinical significance of HER-2/neu oncogene amplification in primary breast cancer. The South Australian Breast Cancer Study GroupJ Clin Oncol199311193619428105035
- BerchuckAKamelAWhitakerROverexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancerCancer Res199050408740911972347
- SlamonDJGodolphinWJonesLAStudies of the HER-2/neu proto-oncogene in human breast and ovarian cancerScience19892447077122470152
- LemmensKDoggenKDe KeulenaerGWRole of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failureCirculation200711695496017709650
- PentassugliaLTimolatiFSeifrizFAbudukadierKSuterTMZuppingerCInhibition of ErbB2/neuregulin signaling augments paclitaxel-induced cardiotoxicity in adult ventricular myocytesExp Cell Res20073131588160117400210
- SandooAKitasGDCarmichaelAREndothelial dysfunction as a determinant of trastuzumab-mediated cardiotoxicity in patients with breast cancerAnticancer Res2014341147115124596352
- KuramochiYGuoXSawyerDBNeuregulin activates erbB2-dependent src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytesJ Mol Cell Cardiol20064122823516769082
- SandooAvan ZantenJJMetsiosGSCarrollDKitasGDThe endothelium and its role in regulating vascular toneOpen Cardiovasc Med J2010430231221339899
- PentassugliaLSawyerDBThe role of Neuregulin-1beta/ErbB signaling in the heartExp Cell Res200931562763718801360
- WilcoxJNSubramanianRRSundellCLExpression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vesselsArterioscler Thromb Vasc Biol199717247924889409218
- CaiHHarrisonDGEndothelial dysfunction in cardiovascular diseases: the role of oxidant stressCirc Res20008784084411073878
- ZeglinskiMPremeczSLernerJCongenital absence of nitric oxide synthase 3 potentiates cardiac dysfunction and reduces survival in doxorubicin- and trastuzumab-mediated cardiomyopathyCan J Cardiol20143035936724484915
- ChoiJYBarlowWEAlbainKSNitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trialClin Cancer Res2009155258526619671875
- MortensenKHolckSChristensenIJEndothelial cell nitric oxide synthase in peritumoral microvessels is a favorable prognostic indicator in premenopausal breast cancer patientsClin Cancer Res199951093109710353743
- McNamaraDMHolubkovRPostavaLEffect of the Asp298 variant of endothelial nitric oxide synthase on survival for patients with congestive heart failureCirculation20031071598160212668492
- GrazetteLPBoeckerWMatsuiTInhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathyJ Am Coll Cardiol2004442231223815582322
- NakagamiHTakemotoMLiaoJKNADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophyJ Mol Cell Cardiol20033585185912818576
- CardinaleDColomboASandriMTPrevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibitionCirculation20061142474248117101852
- Di CosimoSHeart to heart with trastuzumab: a review on cardiac toxicityTarget Oncol2011618919522125051
- GordonLIBurkeMASinghATBlockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathwaysJ Biol Chem20092842080208719017630
- FischerDRossaSLandmesserUEndothelial dysfunction in patients with chronic heart failure is independently associated with increased incidence of hospitalization, cardiac transplantation, or deathEur Heart J200526656915615801
- de BerrazuetaJRGuerra-RuizAGarcía-UnzuetaMTEndothelial dysfunction, measured by reactive hyperaemia using strain-gauge plethysmography, is an independent predictor of adverse outcome in heart failureEur J Heart Fail20101247748320354033
- HornigBMaierVDrexlerHPhysical training improves endothelial function in patients with chronic heart failureCirculation1996932102148548890
- HornigBArakawaNKohlerCDrexlerHVitamin C improves endothelial function of conduit arteries in patients with chronic heart failureCirculation1998973633689468210
- BrutsaertDLFransenPAndriesLJDe KeulenaerGWSysSUCardiac endothelium and myocardial functionCardiovasc Res1998382812909709389
- LinkeARecchiaFZhangXHintzeTHAcute and chronic endothelial dysfunction: implications for the development of heart failureHeart Fail Rev20038879712652162
- AlkaitisMSCrabtreeMJRecoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recyclingCurr Heart Fail Rep2012920021022711313
- MoensALTakimotoETocchettiCGReversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategyCirculation20081172626263618474817
- SeddonMMelikianNDworakowskiREffects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivoCirculation20091192656266219433760
- HornigBArakawaNHaussmannDDrexlerHDifferential effects of quinaprilat and enalaprilat on endothelial function of conduit arteries in patients with chronic heart failureCirculation199898284228489860785
- GiannattasioCAchilliFGrappioloARadial artery flow-mediated dilatation in heart failure patients: effects of pharmacological and nonpharmacological treatmentHypertension2001381451145511751734
- OlivaSCioffiGFrattiniSItalian Cardio-Oncological NetworkAdministration of angiotensin-converting enzyme inhibitors and β-blockers during adjuvant trastuzumab chemotherapy for nonmetastatic breast cancer: marker of risk or cardioprotection in the real world?Oncologist20121791792422673631
- HerrmannJHerrmannSMHaddadTCNew-onset heart failure in association with severe hypertension during trastuzumab therapyMayo Clin Proc2014891734173925441402
- NadarSBlannADLipGYEndothelial dysfunction: methods of assessment and application to hypertensionCurr Pharm Des2004103591360515579056
- BuusNHBøttcherMHermansenFSanderMNielsenTTMulvanyMJInfluence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemiaCirculation20011042305231011696470
- AndersonTJUehataAGerhardMDClose relation of endothelial function in the human coronary and peripheral circulationsJ Am Coll Cardiol199526123512417594037
- TakaseBHamabeASatomuraKClose relationship between the vasodilator response to acetylcholine in the brachial and coronary artery in suspected coronary artery diseaseInt J Cardiol2005105586616207546
- GokceNKeaneyJFJrHunterLMPredictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular diseaseJ Am Coll Cardiol2003411769177512767663
- SchächingerVBrittenMBZeiherAMPrognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart diseaseCirculation20001011899190610779454
- RossiRNuzzoAOriglianiGModenaMGPrognostic role of flow-mediated dilation and cardiac risk factors in post-menopausal womenJ Am Coll Cardiol200851997100218325438