Functional and gene expression analysis of hTERT overexpressed endothelial cells

References

• AssmusBUrbichCAicherA2003HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genesCir. Res92104955
   PubMed Web of Science ®Google Scholar
• BodnarAGOuelletteMFrolkisM1998Extension of life-span by introduction of telomerase into normal human cellsScience279349529454332
   PubMed Web of Science ®Google Scholar
• CarmelietPLampugnaniMGMoonsL1999Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesisCell981475710428027
   PubMed Web of Science ®Google Scholar
• CrowderRJFreemanRS1998Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neuronsJ Neurosci182933439526010
   PubMed Web of Science ®Google Scholar
• EvesEMXiongWBellacosaA1998Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell lineMol Cell Biol182143529528786
   PubMed Web of Science ®Google Scholar
• FrankeTFKaplanDRCantleyLC1997Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bishosphateScience27566589005852
   PubMed Web of Science ®Google Scholar
• FreedmanDAFolkmanJ2004Maintenance of G1 checkpoint controls in telomerase-immortalized endothelial cellsCell Cycle38111615118409
   PubMed Web of Science ®Google Scholar
• GagnonECattaruzziPGriffithM2002Human vascular endothelial cells with extended life spans: in vitro cell response, protein expression, and angiogenesisAngiogenesis5213312549857
   PubMedGoogle Scholar
• GerberHPMcMurtreyAKowalskiJ1998Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3’-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activationJ Biol Chem27330336439804796
   PubMed Web of Science ®Google Scholar
• GreiderCW1990Telomerase, telomerase and senescenceBioessays1236392241933
   PubMed Web of Science ®Google Scholar
• GriendlingKKUshio-FukaiM2000Reactive oxygen species as mediators of angiotensin II signalingRegul Pept9121710967199
   PubMed Web of Science ®Google Scholar
• HaendelerJHoffmannJDiehlJF2004Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cellsCirc Res94703515059938
   PubMed Web of Science ®Google Scholar
• HarleyCBFutcherABGreiderCW1990Telomerase shorten during ageing of human fibroblastsNature345458602342578
   PubMed Web of Science ®Google Scholar
• HastieNDDempsterMDunlopMG1990Telomere reduction in human colorectal carcinoma and with agingNature34686682392154
   PubMed Web of Science ®Google Scholar
• JiangXRJimenezGChangE1999Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotypeNat Genet21111149916802
   PubMed Web of Science ®Google Scholar
• KimIKimHGSoJN2000Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3’-Kinase/Akt signal transduction pathwayCirc Res8624910625301
   PubMed Web of Science ®Google Scholar
• KiyonoTFosterSAKoopJI1998Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cellsNature3968489817205
   PubMed Web of Science ®Google Scholar
• KontosCDStaufferTPYangWP1998Tyrosin 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and AktMol Cell Biol184131409632797
   PubMed Web of Science ®Google Scholar
• KureishiYLuoZShiojimaI2000The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animaksNat Med610041010973320
   PubMed Web of Science ®Google Scholar
• KurzDJDecarySHongY2004Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cellsJ Cell Sci11724172615126641
   PubMed Web of Science ®Google Scholar
• LuoZFujioYKureishiY2000Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivoJ Clin Invest106493910953024
   PubMed Web of Science ®Google Scholar
• MoralesCPHoltSEOuelletteM1999Absence of cancer-associated changes in human fibroblasts immortalized with telomeraseNat Genet21115189916803
   PubMed Web of Science ®Google Scholar
• MurasawaSLlevadotJSilverM2002Constitutive human telomerase reverse trascriptase expression enhances regenerative properties of expression enhances regenerative properties of endothelial progenitor cellsCirculation1061133912196341
   PubMed Web of Science ®Google Scholar
• NakamuraTMMorinGBChapmanKB1997Telomerase catalytic subunit homologs from fission yeast and humanScience27795599252327
   PubMed Web of Science ®Google Scholar
• NisatoREHarrisonJABuserR2004Generation and characterization of telomerase-transfected human lymphatic endothelial cells with an extended life spanAm J Pathol165112415215158
   PubMed Web of Science ®Google Scholar
• NishidaMMaruyamaYTanakaR2000Gαi and Gαo are target proteins of reactive oxygen speciesNature408492511100733
   PubMed Web of Science ®Google Scholar
• NishidaMScheyKLTakagaharaS2002Activation mechanism of Gi and Go by reactive oxygen speciesJ Biol Chem27790364211781308
   PubMed Web of Science ®Google Scholar
• PapapetropoulosAFultonDMahboubiK2000Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathwayJ Biol Chem2759102510734041
   PubMed Web of Science ®Google Scholar
• ShaoRGuoX2004Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of invitro angiogenesisBiochem Biophys Res Commun3217889415358096
   PubMed Web of Science ®Google Scholar
• UlrichEDuwelAKauffmann-ZehA1998Specific TrkA survival signals interfere with different apoptotic pathwaysOncogene16825329484773
   PubMed Web of Science ®Google Scholar
• WrightWEShayJW1992The two-stage mechanism controlling cellular senescence and immortalizationExp Gerontol2738391333985
   PubMed Web of Science ®Google Scholar
• YangJChangECherryAM1999Human endothelial cell life extension by telomerase expressionJ Biol Chem27426141810473565
   PubMed Web of Science ®Google Scholar
• ZaccagniniGGaetanoCDella PietraL2005Telomerase mediates vascular endothelial growth factor-dependent responsiveness in a rat model of hind limb ischemiaJ Biol Chem28014790815687494
   PubMed Web of Science ®Google Scholar