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Review

Update on terbinafine with a focus on dermatophytoses

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Pages 49-63 | Published online: 21 Apr 2009

References

  • BrownMTraynorMTreatment of fungal nail infectionsDrug Delivery Report2007Spring–Summer1719
  • SuhDCShinHRautMTavakkolAUsage patterns of medical services and prescription drugs in patients with tinea capitisJ Am Acad Dermatol20045086
  • BirnbaumJEPharmacology of the allylaminesJ Am Acad Dermatol1990234 Pt 27827852229523
  • GanzingerUStutzAPetranyiGStephenAAllylamines: topical and oral treatment of dermatomycoses with a new class of antifungal agentsActa Derm Venereol Suppl (Stockh)19861211551603459341
  • RyderNSSpecific inhibition of fungal sterol biosynthesis by SF 86–327, a new allylamine antimycotic agentAntimicrob Agents Chemother19852722522564039119
  • RyderNSTerbinafine: mode of action and properties of the squalene epoxidase inhibitionBr J Dermatol1992126 Suppl 39271543672
  • RyderNSDupontMCInhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymesBiochem J198523037657703877503
  • ClaytonYMRelevance of broad-spectrum and fungicidal activity of antifungals in the treatment of dermatomycosesBr J Dermatol1994130 Suppl 43788186143
  • DixonDMPolakAIn vitro and in vivo drug studies with three agents of central nervous system phaeohyphomycosisChemotherapy19873321291403568799
  • OddsFCEffects of temperature on anti-Candida activities of antifungal antibioticsAntimicrob Agents Chemother19933746856918494363
  • PetranyiGMeingassnerJGMiethHActivity of terbinafine in experimental fungal infections of laboratory animalsAntimicrob Agents Chemother19873110155815613435103
  • PetranyiGMeingassnerJGMiethHAntifungal activity of the allylamine derivative terbinafine in vitroAntimicrob Agents Chemother1987319136513683674847
  • PetranyiGRyderNSStutzAAllylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidaseScience19842244654123912416547247
  • SchmittHJBernardEMAndradeJEdwardsFSchmittBArmstrongDMIC and fungicidal activity of terbinafine against clinical isolates of Aspergillus sppAntimicrob Agents Chemother19883257807813134851
  • ShadomySEspinel-IngroffAGebhartRJIn-vitro studies with SF 86–327, a new orally active allylamine derivativeSabouraudia19852321251322990057
  • VenugopalPVVenugopalTVAntidermatophytic activity of allyl-amine derivativesIndian J Pathol Microbiol19943743813887868170
  • Standards NCfCLReference method for broth dilution antifungal susceptibility testing of filamentous fungi. Approved StandardNCCLS document M38-A2Wayne, PAClinical and Laboratory Standards Institute2008
  • GohCLTayYKAliKBKohMTSeowCSIn vitro evaluation of griseofulvin, ketoconazole, and itraconazole against various dermatophytes in SingaporeInt J Dermatol199433107337378002147
  • GrantSMClissoldSPItraconazole. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycosesDrugs19893733103442540949
  • HeelRCBrogdenRNCarmineAMorleyPASpeightTMAveryGSKetoconazole: a review of its therapeutic efficacy in superficial and systemic fungal infectionsDrugs1982231–21366276122
  • HowardRAlyRFriedenIAnalysis of trychophyton tonsurans sensitivity to griseofulvin in vitro (abstract)Clin Res199341420A
  • VenugopalPVVenugopalTVDisk diffusion susceptibility testing of dermatophytes with allylaminesInt J Dermatol199433107307328002146
  • VenugopalPVVenugopalTVAntidermatophytic activity of garlic (Allium sativum) in vitroInt J Dermatol19953442782797790146
  • da Silva BarrosMEde Assis SantosDHamdanJSEvaluation of susceptibility of Trichophyton mentagrophytes and Trichophyton rubrum clinical isolates to antifungal drugs using a modified CLSI microdilution method (M38-A)J Med Microbiol200756Pt 451451817374893
  • GhannoumMAWraithLACaiBNyiradyJIshamNSusceptibility of dermatophyte isolates obtained from a large worldwide terbinafine tinea capitis clinical trialBr J Dermatol2008159371171318510668
  • CoelhoLMAquino-FerreiraRMaffeiCMMartinez-RossiNMIn vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidiaJ Antimicrob Chemother200862475876118552341
  • ZengYBQianYSMaLGuHNGenome-wide expression profiling of the response to terbinafine in Candida albicans using a cDNA microarray analysisChin Med J (Engl)2007120980781317531123
  • CervelattiEPFachinALFerreira-NozawaMSMartinez-RossiNMMolecular cloning and characterization of a novel ABC transporter gene in the human pathogen Trichophyton rubrumMed Mycol200644214114716519017
  • GraminhaMARochaEMPradeRAMartinez-RossiNMTerbinafine resistance mediated by salicylate 1-monooxygenase in Aspergillus nidulansAntimicrob Agents Chemother20044893530353515328121
  • OsborneCSHofbauerBFavreBRyderNSIn vitro analysis of the ability of Trichophyton rubrum to become resistant to terbinafineAntimicrob Agents Chemother200347113634363614576134
  • OsborneCSLeitnerIFavreBRyderNSAmino acid substitution in Trichophyton rubrum squalene epoxidase associated with resistance to terbinafineAntimicrob Agents Chemother20054972840284415980358
  • OsborneCSLeitnerIHofbauerBFieldingCAFavreBRyderNSBiological, biochemical, and molecular characterization of a new clinical Trichophyton rubrum isolate resistant to terbinafineAntimicrob Agents Chemother20065062234223616723593
  • RochaEMAlmeidaCBMartinez-RossiNMIdentification of genes involved in terbinafine resistance in Aspergillus nidulansLett Appl Microbiol200235322823212180946
  • Martinez-RossiNMPeresNTRossiAAntifungal resistance mechanisms in dermatophytesMycopathologia20081665–636938318478356
  • Schuetzer-MuehlbauerMWillingerBKrapfGEnzingerSPresterlEKuchlerKThe Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofunginMol Microbiol200348122523512657057
  • KohliASmritiMukhopadhyayKRattanAPrasadRIn vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetryAntimicrob Agents Chemother20024641046105211897588
  • MagaldiSMataSHartungCVerdeGDeibisLRoldanYIn vitro susceptibility of 137 Candida sp isolates from HIV positive patients to several antifungal drugsMycopathologia20011492636811265163
  • vanden BosscheHMarichalPOddsFCLe JeuneLCoeneMCCharacterization of an azole-resistant Candida glabrata isolateAntimicrob Agents Chemother19923612260226101482129
  • RyderNSLeitnerIActivity of terbinafine against Aspergillus in vitro, in combination with amphotericin B or triazoles (Abstract E54)36th Interscience Conference on Antimicrobial Agents and Chemotherapy1996 Sept 15–18New Orleans, LA1996
  • FothergillAWLeitnerIMeingassnerJGRyderNSRinaldiMGCombination antifungal susceptibility testing of terbinafine and the triazoles fluconazole and itraconazole (Abstract E53)36th Interscience Conference on Antimicrobial Agents and Chemotherapy1996 September 15–18New Orleans, LA1996
  • RoderoLVitaleRHochenfellnerFCanteosCDavelGIn vitro activity of terbinafine in combination with triazole drugs against fluconazole resistant candida species (Abstract E56)36th Interscience Conference on Antimicrobial Agents and Chemotherapy1996 September 15–18New Orleans, LA1996
  • LiLWangZLiRLuoSSunXIn vitro evaluation of combination antifungal activity against Fusarium species isolated from ocular tissues of keratomycosis patientsAm J Ophthalmol2008146572472818707669
  • Abdel-RahmanSMHerronJFallon-FriedlanderSHauffeSHorowitzARiviereGJPharmacokinetics of terbinafine in young children treated for tinea capitisPediatr Infect Dis J2005241088689116220086
  • NejjamFZagulaMCabiacMDGuessousNHumbertHLakhdarHPilot study of terbinafine in children suffering from tinea capitis: evaluation of efficacy, safety and pharmacokineticsBr J Dermatol19951321981057756158
  • JiangXWangNZhangZJTianYChenYPharmacokinetics and comparative bioavailability of two terbinafine hydrochloride formulations after single-dose administration in Chinese healthy subjectsArzneimittelforschung200858736336618751504
  • KovarikJMMuellerEAZehenderHDenouelJCaplainHMilleriouxLMultiple-dose pharmacokinetics and distribution in tissue of terbinafine and metabolitesAntimicrob Agents Chemother19953912273827418593011
  • FaergemannJZehenderHDenouelJMilleriouxLLevels of terbinafine in plasma, stratum corneum, dermis-epidermis (without stratum corneum), sebum, hair and nails during and after 250 mg terbinafine orally once per day for four weeksActa Derm Venereol19937343053097904107
  • CramerJKshatriyaBSnoddyASkin pharmacokinetics of terbinafine in healthy subjects following once-daily application of 1% emulsion gel or 1% cream for 1, 5, or 7 daysAmerican College of Clinical Pharmacy Annual Meeting2006 October 26St. Louis, MO2006
  • DenouellJBurtinPKshatriyaBSnoddyAPharmacokinetics of terbinafine 1% emulsion gel in healthy volunteers and in patients with tinea cruris/corporisAmerican College of Clinical Pharmacy Annual Meeting2006St. Louis, MO20061026
  • KienzlerJLQueille-RousselCMugglestoneCOrtonneJPLarnierCStratum corneum pharmacokinetics of the anti-fungal drug, terbinafine, in a novel topical formulation, for single-dose application in dermatophytosesCurr Med Res Opin20072361293130217559730
  • GuptaAKSauderDNShearNHAntifungal agents: an overview. Part IIJ Am Acad Dermatol199430691133 quiz 34–67619094
  • JensenJCClinical pharmacokinetics of terbinafine (Lamisil)Clin Exp Dermatol19891421101132689012
  • KovarikJMKirkesseliSHumbertHGrassPKutzKDose-proportional pharmacokinetics of terbinafine and its N-demethylated metabolite in healthy volunteersBr J Dermatol1992126 Suppl 398131543677
  • HillSThomasRSmithSGFinlayAYAn investigation of the pharmacokinetics of topical terbinafine (Lamisil) 1% creamBr J Dermatol199212743964001419761
  • TanumaHDoiMOhtaYNishiyamaSKatsuokaKKanekoSUsefulness of 1% terbinafine HCl (Lamisil) cream for hyperkeratotic-type tinea pedis and its transfer into the horny layerMycoses20004311–1241743211204359
  • JensenJCPharmacokinetics of Lamisil in humansJ Dermatol Treat19901 Suppl 21518
  • RyderNSFrankIInteraction of terbinafine with human serum and serum proteinsJ Med Vet Mycol19923064514601287164
  • KikuchiITanumaHMorimotoKKawanaSUsefulness and pharmacokinetic study of oral terbinafine for hyperkeratotic type tinea pedisMycoses200851171318076589
  • HumbertHCabiacMDDenouelJKirkesseliSPharmacokinetics of terbinafine and of its five main metabolites in plasma and urine, following a single oral dose in healthy subjectsBiopharm Drug Dispos19951686856948573687
  • Abdel-RahmanSMMarcucciKBogeTGotschallRRKearnsGLLeederJSPotent inhibition of cytochrome P-450 2D6-mediated dextromethorphan O-demethylation by terbinafineDrug Metab Dispos199927777077510383919
  • BackDJTjiaJFAbelSMAzoles, allylamines and drug metabolismBr J Dermatol1992126 Suppl 3914181311943
  • SchusterIThe interaction of representative members from two classes of antimycotics--the azoles and the allylamines--with cytochromes P-450 in steroidogenic tissues and liverXenobiotica19851565295464036174
  • VickersAESinclairJRZollingerMHeitzFGlanzelUJohansonLMultiple cytochrome P-450s involved in the metabolism of terbinafine suggest a limited potential for drug-drug interactionsDrug Metab Dispos19992791029103810460803
  • Abdel-RahmanSMGotschallRRKauffmanRELeederJSKearnsGLInvestigation of terbinafine as a CYP2D6 inhibitor in vivoClin Pharmacol Ther199965546547210340911
  • CastbergIHelleJAamoTOProlonged pharmacokinetic drug interaction between terbinafine and amitriptylineTher Drug Monit200527568068216175144
  • HynninenVVOlkkolaKTBertilssonLKurkinenKNeuvonenPJLaineKEffect of terbinafine and voriconazole on the pharmacokinetics of the antidepressant venlafaxineClin Pharmacol Ther200883234234817687273
  • MadaniSBarillaDCramerJWangYPaulCEffect of terbinafine on the pharmacokinetics and pharmacodynamics of desipramine in healthy volunteers identified as cytochrome P450 2D6 (CYP2D6) extensive metabolizersJ Clin Pharmacol200242111211121812412819
  • van der KuyPHHooymansPMNortriptyline intoxication induced by terbinafineBMJ199831671294419492672
  • VenkatakrishnanKvon MoltkeLLGreenblattDJEffects of the antifungal agents on oxidative drug metabolism: clinical relevanceClin Pharmacokinet200038211118010709776
  • Lamisil Package Insert. Sandoz Pharmaceutical Corporation. 1996
  • AhonenJOlkkolaKTNeuvonenPJEffect of itraconazole and terbinafine on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteersBr J Clin Pharmacol19954032702728527290
  • BackDJStevensonPTjiaJFComparative effects of two antimycotic agents, ketoconazole and terbinafine on the metabolism of tolbutamide, ethinyloestradiol, cyclosporin and ethoxycoumarin by human liver microsomes in vitroBr J Clin Pharmacol19892821661702775622
  • SeyfferREichelbaumMJensenJCKlotzUAntipyrine metabolism is not affected by terbinafine, a new antifungal agentEur J Clin Pharmacol19893732312332612536
  • ShahIAWhitingPHOmarGOrmerodADBurkeMDThe effects of retinoids and terbinafine on the human hepatic microsomal metabolism of cyclosporinBr J Dermatol199312943953988217751
  • BreckenridgeAClinical significance of interactions with antifungal agentsBr J Dermatol1992126 Suppl 3919221311944
  • ZehenderHCabiacMDDenouelJFaergemannJDonatschPKutzKElimination kinetics of terbinafine from human plasma and tissue following multiple-dose administration, and comparison with 3 main metabolitesDrug Invest19948203210
  • OdomRPathophysiology of dermatophyte infectionsJ Am Acad Dermatol1993285 Pt 1S2S78496407
  • FaragATahaMHalimSOne-week therapy with oral terbinafine in cases of tinea cruris/corporisBr J Dermatol199413156846867999601
  • EvansEGSeamanRAJamesIGShort-duration therapy with terbinafine 1% cream in dermatophyte skin infectionsBr J Dermatol1994130183878305323
  • BonifazASaulAComparative study between terbinafine 1% emulsion-gel versus ketoconazole 2% cream in tinea cruris and tinea corporisEur J Dermatol200010210710910694308
  • BudimuljaUBramonoKUripKSBasukiSWidodoGRapatzGOnce daily treatment with terbinafine 1% cream (Lamisil) for one week is effective in the treatment of tinea corporis and cruris. A placebo-controlled studyMycoses2001447–830030611714065
  • GreerDLJollyHWJrTreatment of tinea cruris with topical terbinafineJ Am Acad Dermatol1990234 Pt 28008042229527
  • LebwohlMElewskiBEisenDSavinRCEfficacy and safety of terbinafine 1% solution in the treatment of interdigital tinea pedis and tinea corporis or tinea crurisCutis200167326126611270304
  • LedezmaELopezJCMarinPRomeroHFerraraGDe SousaLAjoene in the topical short-term treatment of tinea cruris and tinea corporis in humans. Randomized comparative study with terbinafineArzneimittelforschung199949654454710417874
  • MillikanLEEfficacy and tolerability of topical terbinafine in the treatment of tinea crurisJ Am Acad Dermatol1990234 Pt 27957992229526
  • ZaiasNBermanBCorderoCNHernandezAJacobsonCMillikanLEfficacy of a 1-week, once-daily regimen of terbinafine 1% cream in the treatment of tinea cruris and tinea corporisJ Am Acad Dermatol19932946466488408803
  • ColeGWStricklinGA comparison of a new oral antifungal, terbinafine, with griseofulvin as therapy for tinea corporisArch Dermatol198912511153715392684023
  • del Palacio HernandezALopez GomezSGonzalez LastraFMoreno PalancarPIglesias DiezLA comparative double-blind study of terbinafine (Lamisil) and griseofulvin in tinea corporis and tinea crurisClin Exp Dermatol19901532102162194715
  • VoravutinonVOral treatment of tinea corporis and tinea cruris with terbinafine and griseofulvin: a randomized double blind comparative studyJ Med Assoc Thai19937673883938089640
  • BudimuljaUKuswadjiKBramonoSBasukiJJudanarsoLSUntungSA double-blind, randomized, stratified controlled study of the treatment of tinea imbricata with oral terbinafine or itraconazoleBr J Dermatol1994130 Suppl 4329318186139
  • ShrumJPMillikanLEBatainehOSuperficial fungal infections in the tropicsDermatol Clin19941246876937805297
  • ElewskiBNagashima-WhalenLHoeprichPDJordanMCRonaldARSuperficial fungal infections of the skinInfectious Diseases- A treatise of infectious processes5th ed Philadelphia, PAJB Lippincott Company199410291049
  • HollmenKAKinnunenTKiistalaUVaananenASaarelainenIODeCCEfficacy and tolerability of terbinafine 1% emulsion gel in patients with tinea pedisJ Eur Acad Dermatol Venereol2002161878811952304
  • JamesIGLoria-KanzaYJonesTCShort-duration topical treatment of tinea pedis using terbinafine emulsion gel: results of a dose-ranging clinical trialJ Dermatolog Treat2007183163817538805
  • KortingHCTietzHJBrautigamMMayserPRapatzGPaulCOne week terbinafine 1% cream (Lamisil) once daily is effective in the treatment of interdigital tinea pedis: a vehicle controlled study. LAS-INT-06 Study GroupMed Mycol200139433534011556763
  • LedezmaEMarcanoKJorqueraADe SousaLPadillaMPulgarMEfficacy of ajoene in the treatment of tinea pedis: a double-blind and comparative study with terbinafineJ Am Acad Dermatol2000435 Pt 182983211050588
  • LeenutaphongVNiumpraditNTangwiwatSSritaveesuwanRMuanprasatCDouble-blind study of the efficacy of 1 week topical terbinafine cream compared to 4 weeks miconazole cream in patients with tinea pedisJ Med Assoc Thai199982101006101010561963
  • PatelABrookmanSDBullenMUMarleyJEllisDHWilliamsTTopical treatment of interdigital tinea pedis: terbinafine compared with clotrimazoleAustralas J Dermatol199940419720010570555
  • SchopfRHettlerOBrautigamMWeidingerGKabenUMayserPEfficacy and tolerability of terbinafine 1% topical solution used for 1 week compared with 4 weeks clotrimazole 1% topical solution in the treatment of interdigital tinea pedis: a randomized, double-blind, multi-centre, 8-week clinical trialMycoses1999425–641542010536434
  • de ChauvinMFViguie-VallanetCKienzlerJLLarnierCNovel, single-dose, topical treatment of tinea pedis using terbinafine: results of a dose-finding clinical trialMycoses20085111618076588
  • OrtonneJPKortingHCViguie-VallanetCLarnierCSavalunyEEfficacy and safety of a new single-dose terbinafine 1% formulation in patients with tinea pedis (athlete’s foot): a randomized, double-blind, placebo-controlled studyJ Eur Acad Dermatol Venereol200620101307131317062050
  • SavinRSuccessful treatment of chronic tinea pedis (moccasin type) with terbinafine (Lamisil)Clin Exp Dermatol19891421161192689014
  • SavinRCZaiasNTreatment of chronic moccasin-type tinea pedis with terbinafine: a double-blind, placebo-controlled trialJ Am Acad Dermatol1990234 Pt 28048072229528
  • De KeyserPDe BackerMMassartDLWestelinckKJTwo-week oral treatment of tinea pedis, comparing terbinafine (250 mg/day) with itraconazole (100 mg/day): a double-blind, multicentre studyBr J Dermatol1994130 Suppl 4322258186137
  • HayRJMcGregorJMWuiteJRyattKSZieglerCClaytonYMA comparison of 2 weeks of terbinafine 250 mg/day with 4 weeks of itraconazole 100 mg/day in plantar-type tinea pedisBr J Dermatol199513246046087748753
  • ScherRKOnychomycosis is more than a cosmetic problemBr J Dermatol1994130 Suppl 43158186135
  • DegreefHOnychomycosisBr J Clin Pract Suppl19907191972151117
  • MidgleyGMooreMKCookJCPhanQGMycology of nail disordersJ Am Acad Dermatol1994313 Pt 2S68748077512
  • Baudraz-RosseletFRakosiTWiliPBKenzelmannRTreatment of onychomycosis with terbinafineBr J Dermatol1992126 Suppl 3940461531928
  • FarkasBPaulCDobozyAHunyadiJHorvathAFeketeGTerbinafine (Lamisil) treatment of toenail onychomycosis in patients with insulin-dependent and non-insulin-dependent diabetes mellitus: a multicentre trialBr J Dermatol2002146225426011903236
  • GoodfieldMJAndrewLEvansEGShort term treatment of dermatophyte onychomycosis with terbinafineBMJ19923046835115111541392793
  • PollakRBillsteinSAEfficacy of terbinafine for toenail onychomycosis. A multicenter trial of various treatment durationsJ Am Podiatr Med Assoc200191312713111266494
  • WatsonAMarleyJEllisDWilliamsTTerbinafine in onychomycosis of the toenail: a novel treatment protocolJ Am Acad Dermatol1995335 Pt 17757797593777
  • ZaiasNSerranoLThe successful treatment of finger Trichophyton rubrum onychomycosis with oral terbinafineClin Exp Dermatol19891421201232532084
  • GuptaAKGregurek-NovakTEfficacy of itraconazole, terbinafine, fluconazole, griseofulvin and ketoconazole in the treatment of Scopulariopsis brevicaulis causing onychomycosis of the toesDermatology2001202323523811385230
  • WarshawEMNelsonDCarverSMZielkeGRWebsterNLederleFAA pilot evaluation of pulse itraconazole vs terbinafine for treatment of Candida toenail onychomycosisInt J Dermatol200544978578816135154
  • WongCKChoYLVery short duration therapy with oral terbinafine for fingernail onychomycosisBr J Dermatol199513323293317547412
  • AlbaneseGDi CintioRMartiniCNicolettiAShort therapy for tinea unguium with terbinafine: four different courses of treatmentMycoses1995385–62112148531933
  • JenningsMBPollakRHarklessLBKianifardFTavakkolATreatment of toenail onychomycosis with oral terbinafine plus aggressive debridement: IRON-CLAD, a large, randomized, open-label, multicenter trialJ Am Podiatr Med Assoc200696646547317114599
  • AvnerSNirNHenriTCombination of oral terbinafine and topical ciclopirox compared to oral terbinafine for the treatment of onychomycosisJ Dermatolog Treat2005165–632733016428154
  • BaranRTopical amorolfine for 15 months combined with 12 weeks of oral terbinafine, a cost-effective treatment for onychomycosisBr J Dermatol2001145 Suppl 60151911777260
  • BaranRSigurgeirssonBde BerkerDKaufmannRLechaMFaergemannJA multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a combination therapy with amorolfine nail lacquer and oral terbinafine compared with oral terbinafine alone for the treatment of onychomycosis with matrix involvementBr J Dermatol2007157114915717553051
  • GuptaAKCiclopirox topical solution, 8% combined with oral terbinafine to treat onychomycosis: a randomized, evaluator-blinded studyJ Drugs Dermatol20054448148516004022
  • SigurgeirssonBElewskiBERichPAOpperCCaiBNyiradyJIntermittent versus continuous terbinafine in the treatment of toenail onychomycosis: a randomized, double-blind comparisonJ Dermatolog Treat2006171384416467022
  • WarshawEMFettDDBloomfieldHEGrillJPNelsonDBQuinteroVPulse versus continuous terbinafine for onychomycosis: a randomized, double-blind, controlled trialJ Am Acad Dermatol200553457858416198776
  • NakanoNHirumaMShirakiYChenXPorgpermdeeSIkedaSCombination of pulse therapy with terbinafine tablets and topical terbinafine cream for the treatment of dermatophyte onychomycosis: a pilot studyJ Dermatol2006331175375817073989
  • JaiswalASharmaRPGargAPAn open randomized comparative study to test the efficacy and safety of oral terbinafine pulse as a monotherapy and in combination with topical ciclopirox olamine 8% or topical amorolfine hydrochloride 5% in the treatment of onychomycosisIndian J Dermatol Venereol Leprol200773639339618032857
  • TakahataYHirumaMShirakiYTokuhisaYSugitaTMutoMTreatment of dermatophyte onychomycosis with three pulses of terbinafine (500 mg day for a week)Mycoses2009521727618444971
  • FaergemannJAndersonCHersleKHradilENordinPKaamanTDouble-blind, parallel-group comparison of terbinafine and griseofulvin in the treatment of toenail onychomycosisJ Am Acad Dermatol1995325 Pt 17507537722020
  • HanekeETauschIBrautigamMWeidingerGWelzelDShort-duration treatment of fingernail dermatophytosis: a randomized, double-blind study with terbinafine and griseofulvin. LAGOS III Study GroupJ Am Acad Dermatol199532172777822520
  • HofmannHBrautigamMWeidingerGZaunHTreatment of toenail onychomycosis. A randomized, double-blind study with terbinafine and griseofulvin. LAGOS II Study GroupArch Dermatol199513189199227632064
  • ArenasRDominguez-CheritJFernandezLMOpen randomized comparison of itraconazole versus terbinafine in onychomycosisInt J Dermatol19953421381437737776
  • BrautigamMNoltingSSchopfREWeidingerGRandomised double blind comparison of terbinafine and itraconazole for treatment of toenail tinea infection. Seventh Lamisil German Onychomycosis Study GroupBMJ199531170109199227580551
  • DegreefHdel PalacioAMygindSGinterGPinto SoaresAZuluaga de CadenaARandomized double-blind comparison of short-term itraconazole and terbinafine therapy for toenail onychomycosisActa Derm Venereol199979322122310384922
  • ArcaETastanHBAkarAKurumluZGurARAn open, randomized, comparative study of oral fluconazole, itraconazole and terbinafine therapy in onychomycosisJ Dermatolog Treat20021313912006131
  • GuptaAKGoverMDLyndeCWPulse itraconazole vs continuous terbinafine for the treatment of dermatophyte toenail onychomycosis in patients with diabetes mellitusJ Eur Acad Dermatol Venereol200620101188119317062029
  • KejdaJItraconazole pulse therapy vs continuous terbinafine dosing for toenail onychomycosisPostgrad Med1999Spec No: 12–15
  • MishraMPandaPTripathySSenguptaSMishraKAn open randomized comparative study of oral itraconazole pulse and terbinafine pulse in the treatment of onychomycosisIndian J Dermatol Venereol Leprol200571426226616394436
  • SigurgeirssonBBillsteinSRantanenTRuzickaTdi FonzoEVermeerBJL.I.ON. Study: efficacy and tolerability of continuous terbinafine (Lamisil) compared to intermittent itraconazole in the treatment of toenail onychomycosis. Lamisil vs Itraconazole in OnychomycosisBr J Dermatol1999141 Suppl 5651410730908
  • HeikkilaHStubbSLong-term results in patients with onychomycosis treated with terbinafine or itraconazoleBr J Dermatol2002146225025311903235
  • SigurgeirssonBOlafssonJHSteinssonJBPaulCBillsteinSEvansEGLong-term effectiveness of treatment with terbinafine vs itraconazole in onychomycosis: a 5-year blinded prospective follow-up studyArch Dermatol2002138335335711902986
  • HavuVHeikkilaHKuokkanenKNuutinenMRantanenTSaariSA double-blind, randomized study to compare the efficacy and safety of terbinafine (Lamisil) with fluconazole (Diflucan) in the treatment of onychomycosisBr J Dermatol200014219710210651701
  • BaranRde DonckerPLateral edge nail involvement indicates poor prognosis for treating onychomycosis with the new systemic antifungalsActa Derm Venereol199676182838721507
  • SigurgeirssonBPaulCCurranDEvansEGPrognostic factors of mycological cure following treatment of onychomycosis with oral antifungal agentsBr J Dermatol200214761241124312452877
  • SommerSSheehan-DareRAGoodfieldMJEvansEGPrediction of outcome in the treatment of onychomycosisClin Exp Dermatol200328442542812823307
  • RobertsDTEvansEGSubungual dermatophytoma complicating dermatophyte onychomycosisBr J Dermatol199813811891909536247
  • O’BrienJMCommon skin problems of infancy, childhood, and adolescencePrim Care1995221991157777640
  • Abdel-RahmanSMNahataMCPowellDAResponse to initial griseofulvin therapy in pediatric patients with tinea capitisAnn Pharmacother19973144064109100999
  • BronsonDMDesaiDRBarskySFoleySMAn epidemic of infection with Trichophyton tonsurans revealed in a 20-year survey of fungal infections in ChicagoJ Am Acad Dermatol1983833223306220031
  • LaudeTAShahBRLynfieldYTinea capitis in BrooklynAm J Dis Child198213612104710507148756
  • PrevostENonfluorescent tinea capitis in Charleston, SC. A diagnostic problemJAMA19792421617651767480604
  • FriedlanderSFAlyRKrafchikBBlumerJHonigPStewartDTerbinafine in the treatment of Trichophyton tinea capitis: a randomized, double-blind, parallel-group, duration-finding studyPediatrics2002109460260711927703
  • HammHSchwinnABrautigamMWeidingerGShort duration treatment with terbinafine for tinea capitis caused by Trichophyton or Microsporum species. The Study GroupBr J Dermatol1999140348048210233270
  • HaroonTSHussainIMahmoodANagiAHAhmadIZahidMAn open clinical pilot study of the efficacy and safety of oral terbinafine in dry non-inflammatory tinea capitisBr J Dermatol1992126 Suppl 3947501543673
  • KrafchikBPelletierJAn open study of tinea capitis in 50 children treated with a 2-week course of oral terbinafineJ Am Acad Dermatol1999411606310411412
  • AsteNPauMTinea capitis caused by Microsporum canis treated with terbinafineMycoses2004479–1042843015504128
  • KoumantakiEKakourouTRallisERigaPGeorgallaSDoubled dose of oral terbinafine is required for Microsporum canis tinea capitisPediatr Dermatol200118433934211576412
  • SilmHKarelsonMTerbinafine: efficacy and tolerability in young children with tinea capitis due to Microsporum canisJ Eur Acad Dermatol Venereol200216322823012195561
  • AlviKHIqbalNKhanKAHaroonTSHussainIAmanSShusterSJafaryMHA randomized double-blind trial of the efficacy and tolerability of terbinafine once daily compared to griseofulvin once daily in the treatment of tinea capitisRoyal Society of Medicine Services International Congress Series19923540
  • Caceres-RiosHRuedaMBallonaRBustamanteBComparison of terbinafine and griseofulvin in the treatment of tinea capitisJ Am Acad Dermatol2000421 Pt 1808410607324
  • FullerLCSmithCHCerioRMarsdenRAMidgleyGBeardALA randomized comparison of 4 weeks of terbinafine vs 8 weeks of griseofulvin for the treatment of tinea capitisBr J Dermatol2001144232132711251566
  • LipozencicJSkerlevMOrofino-CostaRZaitzVCHorvathAChouelaEA randomized, double-blind, parallel-group, duration-finding study of oral terbinafine and open-label, high-dose griseofulvin in children with tinea capitis due to Microsporum speciesBr J Dermatol2002146581682312000378
  • UngpakornRAyutyanontTReangchainamSSupanyaSTreatment of Microsporum spp. tinea capitis with pulsed oral terbinafineClin Exp Dermatol200429330030315115516
  • GuptaAKAdamPDlovaNLyndeCWHofstaderSMorarNTherapeutic options for the treatment of tinea capitis caused by Trichophyton species: griseofulvin versus the new oral antifungal agents, terbinafine, itraconazole, and fluconazolePediatr Dermatol200118543343811737692
  • ElewskiBECaceresHWDeLeonLEl ShimySHunterJAKorotkiyNTerbinafine hydrochloride oral granules versus oral griseofulvin suspension in children with tinea capitis: results of two randomized, investigator-blinded, multicenter, international, controlled trialsJ Am Acad Dermatol2008591415418378354
  • FaergemannJZehenderHBoukhabzaASmithSGJonesTCA double-blind comparison of levels of terbinafine and itraconazole in plasma, skin, sebum, hair and nails during and after oral medicationActa Derm Venereol199777174769059688
  • JungEGHaasPJBrautigamMWeidingerGSystemic treatment of skin candidosis: a randomized comparison of terbinafine and ketoconazoleMycoses1994379–103613657746297
  • GianniCRomanoCClinical and histological aspects of toenail onychomycosis caused by Aspergillus spp: 34 cases treated with weekly intermittent terbinafineDermatology2004209210411015316163
  • LiDMXiuDRLiRYSamsonRAde HoogGSWangDLAspergillus flavus myositis in a patient after liver transplantationClin Transplant200822450851118767206
  • Krishnan-NatesanaSChandrasekaraPHManavathuaEKRevankarSGSuccessful treatment of primary cutaneous Aspergillus ustus infection with surgical debridement and a combination of voriconazole and terbinafineDiagn Microbiol Infect Dis200862444344618842377
  • EsterrePInzanCKRamarcelERAndriantsimahavandyARatsioharanaMPecarrereJLTreatment of chromomycosis with terbinafine: preliminary results of an open pilot studyBr J Dermatol1996134Suppl 463336 discussion 408763467
  • XibaoZChangxingLQuanLYuqingHTreatment of chromoblastomycosis with terbinafine: a report of four casesJ Dermatolog Treat200516212112416019628
  • BryanCSSmithCWBergDEKarpRBCurvularia lunata endocarditis treated with terbinafine: case reportClin Infect Dis199316130328448316
  • ZhangJXiLLuCLiXXieTZhangHSuccessful treatment for chromoblastomycosis caused by Fonsecae monophona: a report of three cases in Guangdong, ChinaMycoses200952217618118627476
  • AndersonKLMitraSSaloutiRPhamTATaylorHRFungal keratitis caused by Paecilomyces lilacinus associated with a retained intracorneal hairCornea200423551652115220739
  • FordJGAgeeSGreenhawSTSuccessful medical treatment of a case of Paecilomyces lilacinus keratitisCornea20082791077107918812777
  • OllagueJMde ZuritaAMCaleroGParacoccidioidomycosis (South American blastomycosis) successfully treated with terbinafine: first case reportBr J Dermatol2000143118819110886159
  • GipLTerbinafine for black piedraLancet1993341885311648097860
  • WongPKChingWTKwon-ChungKJMeyerRDDisseminated Phialophora parasitica infection in humans: case report and reviewRev Infect Dis19891157707752682949
  • CoskunBSaralYAkpolatNAtasevenACicekDSporotrichosis successfully treated with terbinafine and potassium iodide: case report and review of the literatureMycopathologia20041581535615487321
  • HullPRVismerHFTreatment of cutaneous sporotrichosis with terbinafineBr J Dermatol1992126 Suppl 3951551543674
  • FinlayAYGlobal overview of LamisilBr J Dermatol1994130 Suppl 43138186133
  • PollakRBillsteinSASafety of oral terbinafine for toenail onychomycosisJ Am Podiatr Med Assoc199787125655709425805
  • VillarsVJonesTCClinical efficacy and tolerability of terbinafine (Lamisil)--a new topical and systemic fungicidal drug for treatment of dermatomycosesClin Exp Dermatol19891421241272689015
  • De BackerMDe VroeyCLesaffreEScheysIDe KeyserPTwelve weeks of continuous oral therapy for toenail onychomycosis caused by dermatophytes: a double-blind comparative trial of terbinafine 250 mg/day versus itraconazole 200 mg/dayJ Am Acad Dermatol1998385 Pt 3S57S639594939
  • DrakeLAShearNHArletteJPCloutierRDanbyFWElewskiBEOral terbinafine in the treatment of toenail onychomycosis: North American multicenter trialJ Am Acad Dermatol1997375 Pt 17407459366820
  • ChangCHYoung-XuYKurthTOravJEChanAKThe safety of oral antifungal treatments for superficial dermatophytosis and onychomycosis: a meta-analysisAm J Med2007120979179817765049
  • HallMMonkaCKruppPO’SullivanDSafety of oral terbinafine: results of a postmarketing surveillance study in 25,884 patientsArch Dermatol199713310121312199382559
  • AgarwalKManasDMHudsonMTerbinafine and fulminant hepatic failureN Engl J Med1999340161292129310215503
  • FernandesNFGellerSAFongTLTerbinafine hepatotoxicity: case report and review of the literatureAm J Gastroenterol19989334594609517658
  • BrownPCAdministration FaDNDA 22–047; Lamisil® (terbinafine hydrochloride) Oral Granules2007
  • LoweGGreenCJenningsPHepatitis associated with terbinafine treatmentBMJ199330668722488443524
  • ParedesAHLewisJHTerbinafine-induced acute autoimmune hepatitis in the setting of hepatitis B virus infectionAnn Pharmacother200741588088417426078
  • CommitteeADRATerbinafine and blood dyscrasiasAustralian Adverse Drug Reactions Bulletin20042319
  • BeltraminelliHSLerchMArnoldABircherAJHaeusermannPAcute generalized exanthematous pustulosis induced by the antifungal terbinafine: case report and review of the literatureBr J Dermatol2005152478078315840114
  • HivnorCMHudkinsMLBonnerBTerbinafine-induced subacute cutaneous lupus erythematosusCutis200881215615718441768
  • MagroCMSchaeferJTWaldmanJKnightDSeilstadKHearneDTerbinafine-induced dermatomyositis: a case report and literature review of drug-induced dermatomyositisJ Cutan Pathol2008351748118096000
  • CarstensJWendelboePSogaardHThestrup-PedersenKToxic epidermal necrolysis and erythema multiforme following therapy with terbinafineActa Derm Venereol19947453913927817681
  • GuptaAKPorgesAJHypersensitivity syndrome reaction to oral terbinafineAustralas J Dermatol19983931711729737044
  • KovacsMJAlshammariSGuentherLBourcierMNeutropenia and pancytopenia associated with oral terbinafineJ Am Acad Dermatol1994315 Pt 18067929931
  • RzanyBMockenhauptMGehringWSchopfEStevens- Johnson syndrome after terbinafine therapyJ Am Acad Dermatol19943035098113475
  • ToddPHalpernSMunroDDOral terbinafine and erythema multiformeClin Exp Dermatol19952032472487671425
  • WachFStolzWHeinRLandthalerMSevere erythema anulare centrifugum-like psoriatic drug eruption induced by terbinafineArch Dermatol199513189609617632075
  • BeutlerMHartmannKKuhnMGartmannJTaste disorders and terbinafineBMJ19933076895268343667
  • BongJLLuckeTWEvansCDPersistent impairment of taste resulting from terbinafineBr J Dermatol199813947477489892929
  • DotyRLHaxelBRObjective assessment of terbinafine-induced taste lossLaryngoscope2005115112035203716319619
  • DuxburyAJOliverRJPembertonMNPersistent impairment of taste associated with terbinafineBr Dent J2000188629529610800234
  • JuhlinLLoss of taste and terbinafineLancet1992339880714831351157
  • LemontHSaboMTerbinafine-associated taste disturbance with normal taste threshold scoresJ Am Podiatr Med Assoc2001911054054111734612
  • OttervangerJPStrickerBHLoss of taste and terbinafineLancet199234088217281355823
  • StrickerBHVan RiemsdijkMMSturkenboomMCOttervangerJPTaste loss to terbinafine: a case-control study of potential risk factorsBr J Clin Pharmacol19964233133188877021
  • GuptaAKGonderJRShearNHDilworthGRThe development of green vision in association with terbinafine therapyArch Dermatol199613278458468678591
  • PriceTStallmanJDretlerRHAnterior uveitis in a patient with AIDS who was treated with terbinafine for oral candidiasis: a potential drug-induced reactionClin Infect Dis19972537527539314484
  • YulekFCagilNCakmakHBAkcayEKSimsekSKansuTBilateral anterior optic neuropathy associated with use of terbinafineClin Experiment Ophthalmol200836548848918925921