Strontium ranelate: a novel treatment for postmenopausal osteoporosis: a review of safety and efficacy

References

• AmmannPShenVRobinB2004Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female ratsJ Bone Miner Res1920122015537445
   PubMed Web of Science ®Google Scholar
• ApostoaeiAI2002Absorption of strontium from the gastrointestinal tract into plasma in healthy human adultsHealth Phys83566512075684
   PubMed Web of Science ®Google Scholar
• ArlotMEDelmasPBurt-PichatB2005The effects of strontium ranelate on bone remodelling and bone safety assessed by histomorphometry in patients with postmenopausal osteoporosisJ Bone Miner Res20Suppl 1S223
   Google Scholar
• BlackDMCummingsSRKarpfDB1996Randomised trial of the effect of alendronate on risk of fracture in women with existing vertebral fracturesLancet3481535418950879
   PubMed Web of Science ®Google Scholar
• BlakeGMFogelmanI2005Long-term effect of strontium ranelate treatment on BMDJ Bone Miner Res201901416234961
   PubMed Web of Science ®Google Scholar
• BlakeGMFogelmanI2006Theoretical model for the interpretation of BMD scans in patients stopping strontium ranelate treatmentJ Bone Miner Res2114172416939400
   PubMed Web of Science ®Google Scholar
• CanalisEHottMDeloffreP1996The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitroBone18517238805991
   PubMed Web of Science ®Google Scholar
• ChesnutCHSkagAChristiansenC2004Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosisJ Bone Miner Res191241915231010
   PubMed Web of Science ®Google Scholar
• DahlSGAllainPMariePJ2001Incorporation and distribution of strontium in boneBone284465311336927
   PubMed Web of Science ®Google Scholar
• EastellRBartonIHannonRA2003Relationship of early changes in bone resorption to the reduction in fracture risk with risedronateJ Bone Miner Res181051612817758
   PubMed Web of Science ®Google Scholar
• EttingerBBlackDMMitlakBH1999Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trialJAMA2826374510517716
   PubMed Web of Science ®Google Scholar
• FogelmanIBlakeGM2005Strontium ranelate for the treatment of osteoporosisBMJ3301400115961793
   PubMed Web of Science ®Google Scholar
• GarneroPShihWCJGineytsE1994Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatmentJ Clin Endocrinol Metab7916937007989477
   PubMed Web of Science ®Google Scholar
• GenantHKWuCYvan KuijkC1993Vertebral fracture assessment using a semiquantitative techniqueJ Bone Miner Res81137488237484
   PubMed Web of Science ®Google Scholar
• HarrisSTWattsNBGenantHK1999Effects of risedronate treatment on vertebral and non-vertebral fractures in women with postmenopausal osteoporosisJAMA28213445210527181
   PubMed Web of Science ®Google Scholar
• LibermanUAWeissSRBrollJ1995Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosisN Engl J Med3331437437477143
   PubMed Web of Science ®Google Scholar
• LindsayRNievesJFormicaC1997Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosisLancet35055059284777
   PubMed Web of Science ®Google Scholar
• LookerACWahnerHWDunnWL1998Updated data on proximal femur bone mineral levels of US adultsOsteoporosis Int846889
   PubMed Web of Science ®Google Scholar
• MariePJHottMModrowskiD1993An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient ratsJ Bone Miner Res8607158511988
   PubMed Web of Science ®Google Scholar
• MarshallJHLloydELRundoJ1973Alkaline earth metabolism in adult man. A report prepared by a task group of Committee 2 of the International Commission on Radiological Protection (ICRP Publication 20)Health Phys24129221
   Google Scholar
• MeunierPJSlosmanDODelmasPD2002Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis – a 2-year randomised placebo controlled trialJ Clin Endocrinol Metab872060611994341
   PubMed Web of Science ®Google Scholar
• MeunierPJRouxCSeemanE2004The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosisN Engl J Med3504596814749454
   PubMed Web of Science ®Google Scholar
• NeerRMArnaudCDZanchettaJR2001Effect of parathyroid hormone (1–34) on fractures and bone mineral density in postmenopausal women with osteoporosisN Engl J Med34414344111346808
   PubMed Web of Science ®Google Scholar
• Pors NielsenSSlosmanDSorensenOH1999Influence of strontium on bone mineral density and bone mineral content measurements by dual x-ray absorptiometryJ Clin Densitom2371910677790
   PubMed Web of Science ®Google Scholar
• ReginsterJYDeroisyRDougadosM2002Prevention of early postmenopausal bone loss by strontium ranelate: the randomised, two-year, double-masked, dose ranging, placebo-controlled PREVOS trialOsteoporosis Int1392531
   PubMed Web of Science ®Google Scholar
• ReginsterJYSeemanEDe VernejoulMC2005Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: treatment of peripheral osteoporosis (TROPOS) studyJ Clin Endocrinol Metab9028162215728210
   PubMed Web of Science ®Google Scholar
• ReginsterJYMeunierPJRouxC2006Strontium ranelate: an anti-osteoporotic treatment demonstrating vertebral and nonvertebral antifracture efficacy over 5 years in postmenopausal osteoporotic womenOsteoporosis Int17Suppl 2S138
   Google Scholar
• RouxCReginsterJYFechtenbaumJ2006Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factorsJ Bone Miner Res215364216598373
   PubMed Web of Science ®Google Scholar
• SeemanEVellasBBenhamouC2006Strontium ranelate reduces the risk of vertebral and nonverebral fractures in women eighty years of age and olderJ Bone Miner Res2111132016813532
   PubMed Web of Science ®Google Scholar
• SlosmanDORizzoliRPichardC1994Longitudinal measurements of regional and whole body bone mass in young healthy adultsOsteoporosis Int418590
   PubMed Web of Science ®Google Scholar
• SowdenEMStitchSR1957Trace elements in human tissue: estimation of the concentrations of stable strontium and calcium in human boneBiochem J67104913471518
   PubMed Web of Science ®Google Scholar
• [SPC] Summary of product characteristics2004Summary of product characteristics. Protelos (Strontium ranelate 2g granules)Neuilly-sur-Seine, FranceLes Laboratories Servier
   Google Scholar